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The map label for this gene is mraY [H]

Identifier: 218927748

GI number: 218927748

Start: 596493

End: 597575

Strand: Direct

Name: mraY [H]

Synonym: YPO0552

Alternate gene names: 218927748

Gene position: 596493-597575 (Clockwise)

Preceding gene: 218927747

Following gene: 218927749

Centisome position: 12.82

GC content: 49.77

Gene sequence:

>1083_bases
ATGTTAGTTTGGTTGGCTGAATACTTAGTGAAATTTTACTCAGGCTTTAACGTCTTTTCCTATTTGACGTTCCGCGCCAT
CGTGAGTCTATTAACCGCACTGTTTATTTCATTGTGGATGGGGCCGCACTTGATTGCCTGGTTGCAAAAGCTGCAAATCG
GTCAGGTTGTGCGTAACGATGGGCCAGAGTCGCATTTCAGTAAGCGCGGTACGCCAACCATGGGCGGCCTGATGATCCTC
TTCTCCATCACCATTTCGGTTCTGATGTGGGCTTATCCCTCTAACCCATATGTCTGGTGTGTGCTGTTCATTCTTATAGG
TTATGGCATCGTCGGTTTTATTGATGATTACCGCAAAGTTGTGCGTAAAAACACCAAGGGTTTGATCGCGCGCTGGAAGT
ATTTCTGGCAGTCAATTATTGCCTTGGCTGCGGCATTCACGATGTACAGCATTGGCAAAGATACCTCGGCCACTGAATTA
GTCGTGCCCTTCTTTAAAGACATCATGCCGCAATTGGGCTTGCTGTATGTCCTGCTGGCATATTTCGTGATTGTGGGTAC
CAGTAACGCGGTTAACCTGACGGATGGGCTGGATGGGTTGGCAATTATGCCGACGGTGTTCGTTGCGGCAGGTTTTGCCT
TAGTCGCTTGGGCAACCGGTAATGTGAACTTTGCCGCTTATCTGCATATTCCTTACCTGCGCCATGCGGGTGAATTGGTC
ATTGTCTGTACCGCGATTGTCGGTGCGGGTTTAGGTTTCTTATGGTTTAACACCTACCCGGCGCAAGTGTTCATGGGCGA
TGTTGGCTCACTGGCACTGGGTGGCGCATTAGGCACTATCGCCGTATTACTGCGTCAGGAATTCTTATTAGTCATTATGG
GTGGGGTCTTCGTGGTTGAAACCCTGTCCGTTATCTTGCAGGTTGGGTCCTTTAAGTTACGTGGGCAGCGTATTTTCCGC
ATGGCTCCGATTCACCATCACTACGAACTGAAAGGCTGGCCAGAACCACGGGTGATCGTGCGTTTCTGGATTATTTCGCT
GATGCTGGTGCTGATTGGCCTGGCGACGCTGAAGGTGCGGTAA

Upstream 100 bases:

>100_bases
ACGCGTTGCTGAACGAATATCCGGTTATCACTGTTTTAATTAAAGGTTCACGTAGCGCCGCTATGGAAAATGTCGTGCGT
GCGTTACAGGAGAAGGCATC

Downstream 100 bases:

>100_bases
TTATGGTTGATTATCAGGGTAAAAAAGTGGTCATCATCGGGCTGGGGCTAACCGGCCTTTCCTGCGTTGATTTCTTTATA
GCGCGTGGTGTCACGCCGCG

Product: phospho-N-acetylmuramoyl-pentapeptide- transferase

Products: NA

Alternate protein names: UDP-MurNAc-pentapeptide phosphotransferase [H]

Number of amino acids: Translated: 360; Mature: 360

Protein sequence:

>360_residues
MLVWLAEYLVKFYSGFNVFSYLTFRAIVSLLTALFISLWMGPHLIAWLQKLQIGQVVRNDGPESHFSKRGTPTMGGLMIL
FSITISVLMWAYPSNPYVWCVLFILIGYGIVGFIDDYRKVVRKNTKGLIARWKYFWQSIIALAAAFTMYSIGKDTSATEL
VVPFFKDIMPQLGLLYVLLAYFVIVGTSNAVNLTDGLDGLAIMPTVFVAAGFALVAWATGNVNFAAYLHIPYLRHAGELV
IVCTAIVGAGLGFLWFNTYPAQVFMGDVGSLALGGALGTIAVLLRQEFLLVIMGGVFVVETLSVILQVGSFKLRGQRIFR
MAPIHHHYELKGWPEPRVIVRFWIISLMLVLIGLATLKVR

Sequences:

>Translated_360_residues
MLVWLAEYLVKFYSGFNVFSYLTFRAIVSLLTALFISLWMGPHLIAWLQKLQIGQVVRNDGPESHFSKRGTPTMGGLMIL
FSITISVLMWAYPSNPYVWCVLFILIGYGIVGFIDDYRKVVRKNTKGLIARWKYFWQSIIALAAAFTMYSIGKDTSATEL
VVPFFKDIMPQLGLLYVLLAYFVIVGTSNAVNLTDGLDGLAIMPTVFVAAGFALVAWATGNVNFAAYLHIPYLRHAGELV
IVCTAIVGAGLGFLWFNTYPAQVFMGDVGSLALGGALGTIAVLLRQEFLLVIMGGVFVVETLSVILQVGSFKLRGQRIFR
MAPIHHHYELKGWPEPRVIVRFWIISLMLVLIGLATLKVR
>Mature_360_residues
MLVWLAEYLVKFYSGFNVFSYLTFRAIVSLLTALFISLWMGPHLIAWLQKLQIGQVVRNDGPESHFSKRGTPTMGGLMIL
FSITISVLMWAYPSNPYVWCVLFILIGYGIVGFIDDYRKVVRKNTKGLIARWKYFWQSIIALAAAFTMYSIGKDTSATEL
VVPFFKDIMPQLGLLYVLLAYFVIVGTSNAVNLTDGLDGLAIMPTVFVAAGFALVAWATGNVNFAAYLHIPYLRHAGELV
IVCTAIVGAGLGFLWFNTYPAQVFMGDVGSLALGGALGTIAVLLRQEFLLVIMGGVFVVETLSVILQVGSFKLRGQRIFR
MAPIHHHYELKGWPEPRVIVRFWIISLMLVLIGLATLKVR

Specific function: First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan [H]

COG id: COG0472

COG function: function code M; UDP-N-acetylmuramyl pentapeptide phosphotransferase/UDP-N-acetylglucosamine-1-phosphate transferase

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glycosyltransferase 4 family. MraY subfamily [H]

Homologues:

Organism=Escherichia coli, GI1786275, Length=360, Percent_Identity=89.7222222222222, Blast_Score=642, Evalue=0.0,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000715
- InterPro:   IPR003524
- InterPro:   IPR018480 [H]

Pfam domain/function: PF00953 Glycos_transf_4; PF10555 MraY_sig1 [H]

EC number: =2.7.8.13 [H]

Molecular weight: Translated: 40077; Mature: 40077

Theoretical pI: Translated: 9.90; Mature: 9.90

Prosite motif: PS01347 MRAY_1 ; PS01348 MRAY_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLVWLAEYLVKFYSGFNVFSYLTFRAIVSLLTALFISLWMGPHLIAWLQKLQIGQVVRND
CEEHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHCC
GPESHFSKRGTPTMGGLMILFSITISVLMWAYPSNPYVWCVLFILIGYGIVGFIDDYRKV
CCHHHHCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
VRKNTKGLIARWKYFWQSIIALAAAFTMYSIGKDTSATELVVPFFKDIMPQLGLLYVLLA
HHCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHH
YFVIVGTSNAVNLTDGLDGLAIMPTVFVAAGFALVAWATGNVNFAAYLHIPYLRHAGELV
HHHHHCCCCCEECCCCCCCHHHHHHHHHHHHHHHEEEECCCCEEEEEEECHHHHHCCCHH
IVCTAIVGAGLGFLWFNTYPAQVFMGDVGSLALGGALGTIAVLLRQEFLLVIMGGVFVVE
HHHHHHHHCCHHHHHHCCCCHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
TLSVILQVGSFKLRGQRIFRMAPIHHHYELKGWPEPRVIVRFWIISLMLVLIGLATLKVR
HHHHHHHHCCCCCCCCHHEEECCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MLVWLAEYLVKFYSGFNVFSYLTFRAIVSLLTALFISLWMGPHLIAWLQKLQIGQVVRND
CEEHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHCC
GPESHFSKRGTPTMGGLMILFSITISVLMWAYPSNPYVWCVLFILIGYGIVGFIDDYRKV
CCHHHHCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
VRKNTKGLIARWKYFWQSIIALAAAFTMYSIGKDTSATELVVPFFKDIMPQLGLLYVLLA
HHCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHH
YFVIVGTSNAVNLTDGLDGLAIMPTVFVAAGFALVAWATGNVNFAAYLHIPYLRHAGELV
HHHHHCCCCCEECCCCCCCHHHHHHHHHHHHHHHEEEECCCCEEEEEEECHHHHHCCCHH
IVCTAIVGAGLGFLWFNTYPAQVFMGDVGSLALGGALGTIAVLLRQEFLLVIMGGVFVVE
HHHHHHHHCCHHHHHHCCCCHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
TLSVILQVGSFKLRGQRIFRMAPIHHHYELKGWPEPRVIVRFWIISLMLVLIGLATLKVR
HHHHHHHHCCCCCCCCHHEEECCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA