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The map label for this gene is ilvH [H]

Identifier: 218927737

GI number: 218927737

Start: 585747

End: 586241

Strand: Direct

Name: ilvH [H]

Synonym: YPO0540

Alternate gene names: 218927737

Gene position: 585747-586241 (Clockwise)

Preceding gene: 218927736

Following gene: 218927738

Centisome position: 12.59

GC content: 52.32

Gene sequence:

>495_bases
ATGCGCCGCCGGATTTTATCAGTACTGCTGGAAAATGAGTCAGGTGCACTCTCACGGGTGGTGGGGCTGTTTTCTCAGCG
TGGCTATAATATCGAAAGCCTGACGGTCGCGCCAACCGATGACCCAACGCTTTCCCGCATGACCATCCAGACCGTGGGTG
ATGCCAAGGTTCTGGAGCAGATTGAAAAGCAGCTGCACAAGTTGGTGGACGTCTTACGTGTCAGTGAGTTGGTTTCTGGC
TCACATGTTGAGCGCGAAATCATGTTGGTGAAGTTGCAAGCCAGTGGTTATGGCCGTGAAGAGGTGAAGCGTTGTGCAGA
AATCTTCCGTGGGCAAATTGTGGATGTGACCGCAACGCTCTATACCGTTCAGCTAGCGGGTACTAGCGAGAAGCTGGATG
CGTTTTTGAATGCGGTGCGTGAAGTCGCTGAAATAGTGGAAGTTGCTCGCTCTGGGATTGTCGGCGTATCGCGTGGTGAC
AAAATCATGCGTTAA

Upstream 100 bases:

>100_bases
TGGATGTGACTGTCGATGAAACAGAACATGTTTACCCGATGCAGATTCGTGGTGGTGGCATGGACGAAATGTGGCTAAGC
AAAACGGAGAGGACTTAATT

Downstream 100 bases:

>100_bases
TTAATGCTGATTTCGCTCTAATGATCGGGCTCAGCGCATAGCGTTGAGCTTTTTTGTGCCCAGAAAACCCCCAGCTAGGC
TGGGGGTTCAGTAAAGCTTT

Product: acetolactate synthase 3 regulatory subunit

Products: NA

Alternate protein names: ALS-III; Acetohydroxy-acid synthase III small subunit; AHAS-III [H]

Number of amino acids: Translated: 164; Mature: 164

Protein sequence:

>164_residues
MRRRILSVLLENESGALSRVVGLFSQRGYNIESLTVAPTDDPTLSRMTIQTVGDAKVLEQIEKQLHKLVDVLRVSELVSG
SHVEREIMLVKLQASGYGREEVKRCAEIFRGQIVDVTATLYTVQLAGTSEKLDAFLNAVREVAEIVEVARSGIVGVSRGD
KIMR

Sequences:

>Translated_164_residues
MRRRILSVLLENESGALSRVVGLFSQRGYNIESLTVAPTDDPTLSRMTIQTVGDAKVLEQIEKQLHKLVDVLRVSELVSG
SHVEREIMLVKLQASGYGREEVKRCAEIFRGQIVDVTATLYTVQLAGTSEKLDAFLNAVREVAEIVEVARSGIVGVSRGD
KIMR
>Mature_164_residues
MRRRILSVLLENESGALSRVVGLFSQRGYNIESLTVAPTDDPTLSRMTIQTVGDAKVLEQIEKQLHKLVDVLRVSELVSG
SHVEREIMLVKLQASGYGREEVKRCAEIFRGQIVDVTATLYTVQLAGTSEKLDAFLNAVREVAEIVEVARSGIVGVSRGD
KIMR

Specific function: Valine and isoleucine biosynthesis; first step. [C]

COG id: COG0440

COG function: function code E; Acetolactate synthase, small (regulatory) subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ACT domain [H]

Homologues:

Organism=Escherichia coli, GI1786266, Length=162, Percent_Identity=87.6543209876543, Blast_Score=287, Evalue=3e-79,
Organism=Saccharomyces cerevisiae, GI6319837, Length=206, Percent_Identity=27.6699029126214, Blast_Score=71, Evalue=8e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004789
- InterPro:   IPR019455
- InterPro:   IPR002912 [H]

Pfam domain/function: PF01842 ACT; PF10369 ALS_ss_C [H]

EC number: =2.2.1.6 [H]

Molecular weight: Translated: 18125; Mature: 18125

Theoretical pI: Translated: 7.52; Mature: 7.52

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRRRILSVLLENESGALSRVVGLFSQRGYNIESLTVAPTDDPTLSRMTIQTVGDAKVLEQ
CHHHHHHHHHCCCCCHHHHHHHHHHHCCCCCCEEEECCCCCCCHHHHHHHHCCCHHHHHH
IEKQLHKLVDVLRVSELVSGSHVEREIMLVKLQASGYGREEVKRCAEIFRGQIVDVTATL
HHHHHHHHHHHHHHHHHHCCCCCCEEEEEEEEECCCCCHHHHHHHHHHHCCCHHEEEEEE
YTVQLAGTSEKLDAFLNAVREVAEIVEVARSGIVGVSRGDKIMR
EEEEECCCHHHHHHHHHHHHHHHHHHHHHHCCCEECCCCCCCCC
>Mature Secondary Structure
MRRRILSVLLENESGALSRVVGLFSQRGYNIESLTVAPTDDPTLSRMTIQTVGDAKVLEQ
CHHHHHHHHHCCCCCHHHHHHHHHHHCCCCCCEEEECCCCCCCHHHHHHHHCCCHHHHHH
IEKQLHKLVDVLRVSELVSGSHVEREIMLVKLQASGYGREEVKRCAEIFRGQIVDVTATL
HHHHHHHHHHHHHHHHHHCCCCCCEEEEEEEEECCCCCHHHHHHHHHHHCCCHHEEEEEE
YTVQLAGTSEKLDAFLNAVREVAEIVEVARSGIVGVSRGDKIMR
EEEEECCCHHHHHHHHHHHHHHHHHHHHHHCCCEECCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 6308579; 1630901; 9278503; 1851954; 2198273 [H]