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The map label for this gene is nhaR [H]

Identifier: 218927668

GI number: 218927668

Start: 502057

End: 502956

Strand: Direct

Name: nhaR [H]

Synonym: YPO0471

Alternate gene names: 218927668

Gene position: 502057-502956 (Clockwise)

Preceding gene: 218927667

Following gene: 218927671

Centisome position: 10.79

GC content: 45.78

Gene sequence:

>900_bases
ATGCGAATGTCACATATTAATTTCAATCATCTTTATTATTTTTGGCAGGTTTGTAAAGAAGGCTCGGTTGTGGGAGCCGC
AGAGGCACTGTTTCTGACTCCGCAAACAATCACCGGCCAAATTAAAGCGCTGGAAGGGCGCTTAGGCGGTAAGCTATTTA
AGCGGCGGGGGCGGGGATTGGTCCCTTCAGAATTGGGGCAACTGGTTTTCCGCTACGCGGATAAAATGTTTATGCTTAGC
CAGGAAATGCTGGATATCGTTAACTACCGTAAAGAATCCCACCTGTTATTCGATGTCGGCGTCGCCGATGCATTATCGAA
GCGTTTAGTGAGTCAGGTTCTGGAAACTGCGGTGGTTGAGCATGAAAAAATTCATCTACGCTGTTTTGAATCCACCCATG
AGATGTTGTTAGAACAACTCAGTCAGCACAAATTGGATATGATCTTGTCTGATTGCCCGGTTGACTCCAGTCAGCAAGAG
GGGTTGTTCTCAGTGAAACTGGGGGAATGCAGTGTCAGTTTCTATTGTCGCCAGCCTGTCCCCGATCTACCTTTCCCTGC
CAGTTTGCAGCAAAAGCGTTTATTGATCCCCGGTCGCCGCTCAATGTTAGGGCGAAAATTACTCAACTGGATTAACAGTA
AAGGCCTGAAGGTAGAGGTTTTGGGGGAATTTGACGATGCTGCCCTGATGAATGCGTTTGCTGTCTATCATGACGCTATC
TTTGTCGCACCAACGATATACGCCGCTGATACTTATGCTAACGATAGTGAAATTATTGAAATTGGTCGTTTAGATAACGT
ACAGGAAGAGTACTACGTTATTTTTGCTGAGCGGATGATCCAACATCCGGCAGTACAGCGGGTATGTAACAAAGATTTTT
CAGCGTTGTTTAACTGTTAA

Upstream 100 bases:

>100_bases
CTGCCCAAGCGCAGGCAGCAATGCTTGGTGGAATTTAAAGATGGTTTGTCGTGCATGAGGCCATGTATCTGGCTTGGCGG
TATGTTAAGGAGATAACAAC

Downstream 100 bases:

>100_bases
GTCAATTCGCTGCAAACAGGCCCACTGCAACTGAGTAGTGGAGCCACTACTGAACGTCATAATTGCCAAACGATAGAGAT
AAAAAAACCGGCCTAAGCCG

Product: transcriptional activator NhaR

Products: NA

Alternate protein names: Na(+)/H(+) antiporter regulatory protein [H]

Number of amino acids: Translated: 299; Mature: 299

Protein sequence:

>299_residues
MRMSHINFNHLYYFWQVCKEGSVVGAAEALFLTPQTITGQIKALEGRLGGKLFKRRGRGLVPSELGQLVFRYADKMFMLS
QEMLDIVNYRKESHLLFDVGVADALSKRLVSQVLETAVVEHEKIHLRCFESTHEMLLEQLSQHKLDMILSDCPVDSSQQE
GLFSVKLGECSVSFYCRQPVPDLPFPASLQQKRLLIPGRRSMLGRKLLNWINSKGLKVEVLGEFDDAALMNAFAVYHDAI
FVAPTIYAADTYANDSEIIEIGRLDNVQEEYYVIFAERMIQHPAVQRVCNKDFSALFNC

Sequences:

>Translated_299_residues
MRMSHINFNHLYYFWQVCKEGSVVGAAEALFLTPQTITGQIKALEGRLGGKLFKRRGRGLVPSELGQLVFRYADKMFMLS
QEMLDIVNYRKESHLLFDVGVADALSKRLVSQVLETAVVEHEKIHLRCFESTHEMLLEQLSQHKLDMILSDCPVDSSQQE
GLFSVKLGECSVSFYCRQPVPDLPFPASLQQKRLLIPGRRSMLGRKLLNWINSKGLKVEVLGEFDDAALMNAFAVYHDAI
FVAPTIYAADTYANDSEIIEIGRLDNVQEEYYVIFAERMIQHPAVQRVCNKDFSALFNC
>Mature_299_residues
MRMSHINFNHLYYFWQVCKEGSVVGAAEALFLTPQTITGQIKALEGRLGGKLFKRRGRGLVPSELGQLVFRYADKMFMLS
QEMLDIVNYRKESHLLFDVGVADALSKRLVSQVLETAVVEHEKIHLRCFESTHEMLLEQLSQHKLDMILSDCPVDSSQQE
GLFSVKLGECSVSFYCRQPVPDLPFPASLQQKRLLIPGRRSMLGRKLLNWINSKGLKVEVLGEFDDAALMNAFAVYHDAI
FVAPTIYAADTYANDSEIIEIGRLDNVQEEYYVIFAERMIQHPAVQRVCNKDFSALFNC

Specific function: Plays a role in the positive regulation of nhaA [H]

COG id: COG0583

COG function: function code K; Transcriptional regulator

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1786202, Length=298, Percent_Identity=79.5302013422819, Blast_Score=503, Evalue=1e-144,
Organism=Escherichia coli, GI1788297, Length=248, Percent_Identity=26.6129032258064, Blast_Score=69, Evalue=3e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 34033; Mature: 34033

Theoretical pI: Translated: 6.60; Mature: 6.60

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.3 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
5.7 %Cys+Met (Translated Protein)
2.3 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
5.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRMSHINFNHLYYFWQVCKEGSVVGAAEALFLTPQTITGQIKALEGRLGGKLFKRRGRGL
CCCCCCCHHHHHHHHHHHHCCCEEECCCEEEECCCHHCCHHHHHHHHHHHHHHHHCCCCC
VPSELGQLVFRYADKMFMLSQEMLDIVNYRKESHLLFDVGVADALSKRLVSQVLETAVVE
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCHHHHHHHHHHHHHHHHHHHH
HEKIHLRCFESTHEMLLEQLSQHKLDMILSDCPVDSSQQEGLFSVKLGECSVSFYCRQPV
HHHHEEEEHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEEEECCEEEEEEECCCC
PDLPFPASLQQKRLLIPGRRSMLGRKLLNWINSKGLKVEVLGEFDDAALMNAFAVYHDAI
CCCCCCCCCCCCEECCCCHHHHHHHHHHHHHCCCCCEEEEECCCCHHHHHHHHHHHHHHH
FVAPTIYAADTYANDSEIIEIGRLDNVQEEYYVIFAERMIQHPAVQRVCNKDFSALFNC
HCCCEEEEECCCCCCCCEEEECCCCCCCHHHHHHHHHHHHHCHHHHHHHCHHHHHHCCC
>Mature Secondary Structure
MRMSHINFNHLYYFWQVCKEGSVVGAAEALFLTPQTITGQIKALEGRLGGKLFKRRGRGL
CCCCCCCHHHHHHHHHHHHCCCEEECCCEEEECCCHHCCHHHHHHHHHHHHHHHHCCCCC
VPSELGQLVFRYADKMFMLSQEMLDIVNYRKESHLLFDVGVADALSKRLVSQVLETAVVE
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCHHHHHHHHHHHHHHHHHHHH
HEKIHLRCFESTHEMLLEQLSQHKLDMILSDCPVDSSQQEGLFSVKLGECSVSFYCRQPV
HHHHEEEEHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEEEECCEEEEEEECCCC
PDLPFPASLQQKRLLIPGRRSMLGRKLLNWINSKGLKVEVLGEFDDAALMNAFAVYHDAI
CCCCCCCCCCCCEECCCCHHHHHHHHHHHHHCCCCCEEEEECCCCHHHHHHHHHHHHHHH
FVAPTIYAADTYANDSEIIEIGRLDNVQEEYYVIFAERMIQHPAVQRVCNKDFSALFNC
HCCCEEEEECCCCCCCCEEEECCCCCCCHHHHHHHHHHHHHCHHHHHHHCHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 2429258; 1630901; 9278503; 3413113; 1316901; 8168494 [H]