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The map label for this gene is serB [H]

Identifier: 218927641

GI number: 218927641

Start: 462755

End: 463735

Strand: Direct

Name: serB [H]

Synonym: YPO0442

Alternate gene names: 218927641

Gene position: 462755-463735 (Clockwise)

Preceding gene: 218927639

Following gene: 218927642

Centisome position: 9.94

GC content: 51.89

Gene sequence:

>981_bases
ATGTCTAATAGTCTGACCTATTGCGATCTGCCTTCGGAGATCTATCAATGGCCGGGTTTGCCACTTTCACTCAGTGGCGA
CGAAGTGATGCCGCTGGATTATCGTGCCGGTCATACAGGTTGGCTGTTGTATGGTAGAAAACTGGATAAACAGCGGATTA
CCGATTTTCAACGTCAGCTTGGTGCGGCCATGGTGATTGTTTCTGCCTGGTGTGTGGAAGATTATCAGGTGATCCGGCTA
GCGGGTAGCCTAACACCACGAATTAAAACGCTGGCCGATGAGAGCGGCCTTGATGTCGCGCCATTGGGGGCGATACCGCA
TCTACGGACTCCCGGCCTGCTGGTCATGGATATGGATTCCACCGCGATCCAAATCGAATGCATTGATGAAATTGCCAAAC
TGGCAGGTGTGGGCGATGAGGTGGCGGCGGTCACTGAACGCGCCATGCAAGGTGAGTTGGATTTCTCGGCCAGTCTGCGC
CAGCGGGTGGCGGCACTGAAAGGAGCCGATGCCAATATTTTGAAGCAAGTCCGTGACGACTTGCCATTGATGCCGGGGTT
GGTCAGCCTGGTGCGTAAACTTCAGGCGTTGGATTGGCATGTGGCTATTGCTTCTGGCGGTTTTACCTATTATGCCGAAT
ACCTGCGTGACAAATTGCGGTTGGTTCATGTTGCCGCGAATGAGCTTGAAATCAAAGACGGCAAACTGACCGGGTGTGTA
CTGGGGCCAATTGTTGATGCGCAATATAAAGCAGATACCCTTATCAAGCTGGCGGAGAAATTGAATATCCCGCTGGCACA
GACTATTGCTATCGGCGATGGCGCTAATGACCTGAAAATGATGCAGGTTGCGGGTTTAGGTTTGGCTTTCCACGCCAAAC
CGAAGGTTTATGCCAAAGCGAAAGTGGCGATCCGTCACGGTGATTTACTGAGTGTTCTCTGCATTTTGACCGGTAGCTTA
AAGCACGAGAGTGGCAAGTAG

Upstream 100 bases:

>100_bases
GCGATAGGATAGCTTGATGCGTTGTTTTACTTGATGCGTTAGTTTTAAATGAGCCGTATATATATATATTGCGTTGTCCC
GGTTTCTACAGGAGTAATTC

Downstream 100 bases:

>100_bases
GCCATTCGTTGATAAATCATTTAGTTATAATCAAGTGTTTAATGATTTTTTTCGTAAAGTATGCGCGCATAAGATTGAGG
TGATGACATGGCGAAAGCAC

Product: phosphoserine phosphatase

Products: NA

Alternate protein names: PSP; PSPase; O-phosphoserine phosphohydrolase [H]

Number of amino acids: Translated: 326; Mature: 325

Protein sequence:

>326_residues
MSNSLTYCDLPSEIYQWPGLPLSLSGDEVMPLDYRAGHTGWLLYGRKLDKQRITDFQRQLGAAMVIVSAWCVEDYQVIRL
AGSLTPRIKTLADESGLDVAPLGAIPHLRTPGLLVMDMDSTAIQIECIDEIAKLAGVGDEVAAVTERAMQGELDFSASLR
QRVAALKGADANILKQVRDDLPLMPGLVSLVRKLQALDWHVAIASGGFTYYAEYLRDKLRLVHVAANELEIKDGKLTGCV
LGPIVDAQYKADTLIKLAEKLNIPLAQTIAIGDGANDLKMMQVAGLGLAFHAKPKVYAKAKVAIRHGDLLSVLCILTGSL
KHESGK

Sequences:

>Translated_326_residues
MSNSLTYCDLPSEIYQWPGLPLSLSGDEVMPLDYRAGHTGWLLYGRKLDKQRITDFQRQLGAAMVIVSAWCVEDYQVIRL
AGSLTPRIKTLADESGLDVAPLGAIPHLRTPGLLVMDMDSTAIQIECIDEIAKLAGVGDEVAAVTERAMQGELDFSASLR
QRVAALKGADANILKQVRDDLPLMPGLVSLVRKLQALDWHVAIASGGFTYYAEYLRDKLRLVHVAANELEIKDGKLTGCV
LGPIVDAQYKADTLIKLAEKLNIPLAQTIAIGDGANDLKMMQVAGLGLAFHAKPKVYAKAKVAIRHGDLLSVLCILTGSL
KHESGK
>Mature_325_residues
SNSLTYCDLPSEIYQWPGLPLSLSGDEVMPLDYRAGHTGWLLYGRKLDKQRITDFQRQLGAAMVIVSAWCVEDYQVIRLA
GSLTPRIKTLADESGLDVAPLGAIPHLRTPGLLVMDMDSTAIQIECIDEIAKLAGVGDEVAAVTERAMQGELDFSASLRQ
RVAALKGADANILKQVRDDLPLMPGLVSLVRKLQALDWHVAIASGGFTYYAEYLRDKLRLVHVAANELEIKDGKLTGCVL
GPIVDAQYKADTLIKLAEKLNIPLAQTIAIGDGANDLKMMQVAGLGLAFHAKPKVYAKAKVAIRHGDLLSVLCILTGSLK
HESGK

Specific function: Unknown

COG id: COG0560

COG function: function code E; Phosphoserine phosphatase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the serB family [H]

Homologues:

Organism=Homo sapiens, GI46249388, Length=171, Percent_Identity=34.5029239766082, Blast_Score=88, Evalue=1e-17,
Organism=Escherichia coli, GI1790849, Length=320, Percent_Identity=75, Blast_Score=496, Evalue=1e-142,
Organism=Caenorhabditis elegans, GI115534454, Length=265, Percent_Identity=29.4339622641509, Blast_Score=65, Evalue=4e-11,
Organism=Saccharomyces cerevisiae, GI6321647, Length=247, Percent_Identity=38.4615384615385, Blast_Score=161, Evalue=2e-40,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005834
- InterPro:   IPR023214
- InterPro:   IPR006383
- InterPro:   IPR023190
- InterPro:   IPR004469 [H]

Pfam domain/function: PF00702 Hydrolase [H]

EC number: =3.1.3.3 [H]

Molecular weight: Translated: 35355; Mature: 35223

Theoretical pI: Translated: 6.63; Mature: 6.63

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSNSLTYCDLPSEIYQWPGLPLSLSGDEVMPLDYRAGHTGWLLYGRKLDKQRITDFQRQL
CCCCCEEECCCHHHHHCCCCEEEECCCEEEECCCCCCCCEEEEECCCCCHHHHHHHHHHH
GAAMVIVSAWCVEDYQVIRLAGSLTPRIKTLADESGLDVAPLGAIPHLRTPGLLVMDMDS
HHHHHHHHHHHHCCHHEEHHHCCCCCHHHHHCCCCCCCEECCCCCCCCCCCCEEEEECCC
TAIQIECIDEIAKLAGVGDEVAAVTERAMQGELDFSASLRQRVAALKGADANILKQVRDD
CEEEEHHHHHHHHHHCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCCHHHHHHHHHC
LPLMPGLVSLVRKLQALDWHVAIASGGFTYYAEYLRDKLRLVHVAANELEIKDGKLTGCV
CCCCHHHHHHHHHHHHCCEEEEEECCCHHHHHHHHHHHHHEEEEECCCEEECCCCEEEEE
LGPIVDAQYKADTLIKLAEKLNIPLAQTIAIGDGANDLKMMQVAGLGLAFHAKPKVYAKA
ECCCCCCCCCHHHHHHHHHHHCCCHHHEEEECCCCCHHHHHHHHCCCEEEECCCCEEEEE
KVAIRHGDLLSVLCILTGSLKHESGK
EEEEECCHHHHHHHHHHCCCCCCCCC
>Mature Secondary Structure 
SNSLTYCDLPSEIYQWPGLPLSLSGDEVMPLDYRAGHTGWLLYGRKLDKQRITDFQRQL
CCCCEEECCCHHHHHCCCCEEEECCCEEEECCCCCCCCEEEEECCCCCHHHHHHHHHHH
GAAMVIVSAWCVEDYQVIRLAGSLTPRIKTLADESGLDVAPLGAIPHLRTPGLLVMDMDS
HHHHHHHHHHHHCCHHEEHHHCCCCCHHHHHCCCCCCCEECCCCCCCCCCCCEEEEECCC
TAIQIECIDEIAKLAGVGDEVAAVTERAMQGELDFSASLRQRVAALKGADANILKQVRDD
CEEEEHHHHHHHHHHCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCCHHHHHHHHHC
LPLMPGLVSLVRKLQALDWHVAIASGGFTYYAEYLRDKLRLVHVAANELEIKDGKLTGCV
CCCCHHHHHHHHHHHHCCEEEEEECCCHHHHHHHHHHHHHEEEEECCCEEECCCCEEEEE
LGPIVDAQYKADTLIKLAEKLNIPLAQTIAIGDGANDLKMMQVAGLGLAFHAKPKVYAKA
ECCCCCCCCCHHHHHHHHHHHCCCHHHEEEECCCCCHHHHHHHHCCCEEEECCCCEEEEE
KVAIRHGDLLSVLCILTGSLKHESGK
EEEEECCHHHHHHHHHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]