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The map label for this gene is deoD [H]

Identifier: 218927639

GI number: 218927639

Start: 460991

End: 461710

Strand: Direct

Name: deoD [H]

Synonym: YPO0440

Alternate gene names: 218927639

Gene position: 460991-461710 (Clockwise)

Preceding gene: 218927638

Following gene: 218927641

Centisome position: 9.91

GC content: 50.0

Gene sequence:

>720_bases
ATGGCAACGCCACATATTAATGCTGAAATGGGTGATTTCGCCGACGTTGTATTGATGCCAGGGGACCCACTGCGGGCAAA
GTTTATTGCAGAAACTTTCCTGCAAGACGTGCGTGAAGTGAATAACGTACGCGGCATGTTGGGTTTCACCGGCACCTATA
AAGGCCGGAAGATTTCTGTGATGGGCCATGGCATGGGGATCCCATCCTGTTCTATCTATGCTAAAGAGCTGATCACTGAT
TTTGGTGTGAAGAAAATCATCCGCGTGGGCTCCTGTGGTGCCGTACGCACCGATGTTAAACTGCGTGATGTAGTGATCGG
AATGGGGGCGTGCACGGATTCCAAAGTTAACCGTATGCGTTTTAAAGATCACGACTATGCGGCGATTGCTGATTTTGAGA
TGACCCGTAATGCGGTTGATGCAGCCAAAGCGAAAGGGGTCAATGTCCGTGTCGGTAACCTCTTCTCTGCGGATCTTTTC
TACACACCAGATCCACAAATGTTTGATGTGATGGAAAAATACGGCATCTTGGGCGTAGAAATGGAAGCCGCCGGTATCTG
CGGCGTAGCGGCAGAGTTTGGTGCGAAGGCACTGACTATCTGCACCGTTTCTGACCATATCCGTACCGGCGAGCAGACTA
CCGCGGCTGAACGTCAGACCACTTTTAATGACATGATTGAGATCGCACTGGAATCTGTGTTACTGGGTGATAACGCGTAA

Upstream 100 bases:

>100_bases
CAGTTCGGCGATTAACATTTCAATTAGGTTAAGGCCTCTATTAGGTTAAAACCGCAATTAAGTTAACATATTAATTCTCT
GATTTTTAAGGAAAGTGATT

Downstream 100 bases:

>100_bases
TCGCGTCTCAAGCTTCTCCCTTTCCAGCGGTTTTTTCTTTCTTCAGCGGTAGAGATCTCTGCCGCTGAATTGATTTATTC
CTCTCTGAATCACTAACGTG

Product: purine nucleoside phosphorylase

Products: NA

Alternate protein names: PNP [H]

Number of amino acids: Translated: 239; Mature: 238

Protein sequence:

>239_residues
MATPHINAEMGDFADVVLMPGDPLRAKFIAETFLQDVREVNNVRGMLGFTGTYKGRKISVMGHGMGIPSCSIYAKELITD
FGVKKIIRVGSCGAVRTDVKLRDVVIGMGACTDSKVNRMRFKDHDYAAIADFEMTRNAVDAAKAKGVNVRVGNLFSADLF
YTPDPQMFDVMEKYGILGVEMEAAGICGVAAEFGAKALTICTVSDHIRTGEQTTAAERQTTFNDMIEIALESVLLGDNA

Sequences:

>Translated_239_residues
MATPHINAEMGDFADVVLMPGDPLRAKFIAETFLQDVREVNNVRGMLGFTGTYKGRKISVMGHGMGIPSCSIYAKELITD
FGVKKIIRVGSCGAVRTDVKLRDVVIGMGACTDSKVNRMRFKDHDYAAIADFEMTRNAVDAAKAKGVNVRVGNLFSADLF
YTPDPQMFDVMEKYGILGVEMEAAGICGVAAEFGAKALTICTVSDHIRTGEQTTAAERQTTFNDMIEIALESVLLGDNA
>Mature_238_residues
ATPHINAEMGDFADVVLMPGDPLRAKFIAETFLQDVREVNNVRGMLGFTGTYKGRKISVMGHGMGIPSCSIYAKELITDF
GVKKIIRVGSCGAVRTDVKLRDVVIGMGACTDSKVNRMRFKDHDYAAIADFEMTRNAVDAAKAKGVNVRVGNLFSADLFY
TPDPQMFDVMEKYGILGVEMEAAGICGVAAEFGAKALTICTVSDHIRTGEQTTAAERQTTFNDMIEIALESVLLGDNA

Specific function: Cleavage Of Guanosine Or Inosine To Respective Bases And Sugar-1-Phosphate Molecules. [C]

COG id: COG0813

COG function: function code F; Purine-nucleoside phosphorylase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the PNP/UDP phosphorylase family [H]

Homologues:

Organism=Escherichia coli, GI1790844, Length=238, Percent_Identity=90.7563025210084, Blast_Score=443, Evalue=1e-126,
Organism=Escherichia coli, GI1790265, Length=234, Percent_Identity=26.9230769230769, Blast_Score=82, Evalue=3e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004402
- InterPro:   IPR018017
- InterPro:   IPR018016
- InterPro:   IPR000845 [H]

Pfam domain/function: PF01048 PNP_UDP_1 [H]

EC number: =2.4.2.1 [H]

Molecular weight: Translated: 25876; Mature: 25745

Theoretical pI: Translated: 5.37; Mature: 5.37

Prosite motif: PS01232 PNP_UDP_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.1 %Cys     (Translated Protein)
5.4 %Met     (Translated Protein)
7.5 %Cys+Met (Translated Protein)
2.1 %Cys     (Mature Protein)
5.0 %Met     (Mature Protein)
7.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MATPHINAEMGDFADVVLMPGDPLRAKFIAETFLQDVREVNNVRGMLGFTGTYKGRKISV
CCCCCCCCCCCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHHCEEEEECCCCCCCEEEE
MGHGMGIPSCSIYAKELITDFGVKKIIRVGSCGAVRTDVKLRDVVIGMGACTDSKVNRMR
EECCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCEECCCEEEHEEEECCCCCCCHHHHHC
FKDHDYAAIADFEMTRNAVDAAKAKGVNVRVGNLFSADLFYTPDPQMFDVMEKYGILGVE
CCCCCCEEEEHHHHHHHHHHHHHHCCCEEEECCEEEECEEECCCCHHHHHHHHCCCEEEE
MEAAGICGVAAEFGAKALTICTVSDHIRTGEQTTAAERQTTFNDMIEIALESVLLGDNA
ECCCCHHHHHHHCCCCEEEEEEEHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure 
ATPHINAEMGDFADVVLMPGDPLRAKFIAETFLQDVREVNNVRGMLGFTGTYKGRKISV
CCCCCCCCCCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHHCEEEEECCCCCCCEEEE
MGHGMGIPSCSIYAKELITDFGVKKIIRVGSCGAVRTDVKLRDVVIGMGACTDSKVNRMR
EECCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCEECCCEEEHEEEECCCCCCCHHHHHC
FKDHDYAAIADFEMTRNAVDAAKAKGVNVRVGNLFSADLFYTPDPQMFDVMEKYGILGVE
CCCCCCEEEEHHHHHHHHHHHHHHCCCEEEECCEEEECEEECCCCHHHHHHHHCCCEEEE
MEAAGICGVAAEFGAKALTICTVSDHIRTGEQTTAAERQTTFNDMIEIALESVLLGDNA
ECCCCHHHHHHHCCCCEEEEEEEHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA