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The map label for this gene is dnaC [H]

Identifier: 218906660

GI number: 218906660

Start: 5284080

End: 5285441

Strand: Reverse

Name: dnaC [H]

Synonym: BCAH820_5578

Alternate gene names: 218906660

Gene position: 5285441-5284080 (Counterclockwise)

Preceding gene: 218906661

Following gene: 218906659

Centisome position: 99.67

GC content: 40.6

Gene sequence:

>1362_bases
ATGAGTGATGTAATGGCTGATCGTACCCCTCCGCATAATATAGAAGCCGAGCAGGCAGTCCTAGGTGCTATATTGATTGA
TCAGGATGCATTAACTTCAGCATCGGAACTATTGGTACCTGACTCATTTTATCGAACAAAACATCAAAAGATTTTTGAAG
TTATGCTTGGATTATCGGATAAGGGGGAACCAATCGACTTAGTAATGATGACGTCAGCGATGGCTGATCAGGGATTACTA
GAAGAAGTTGGTGGGGTTTCTTACTTAGCAGAATTAGCAGAAGTTGTTCCGACTGCTGCTAACGTAGAATATTATGCACG
AATCATAGCTGAAAAAGCACTGTTACGTCGTTTAATTCGAACGGCAACTCATATCGTGTCTGATGGATATGAGAGAGAAG
ATGATGTGGATGGCCTTTTAAATGAGGCTGAGAAAAAAATATTAGAAGTATCTCATCAGACGAATGCGAAAGCATTTCAA
AATATTAAAGACGTTCTTGTAGATGCTTATGATAAAATCGAACTTTTGCATAATCAAAAAGGTGAAGTTACCGGGATACC
AACTGGGTTTACTGAATTAGATAAGATGACGGCAGGGTTCCAGCGAAATGATTTAATCATCGTGGCGGCACGTCCATCGG
TAGGGAAAACGGCATTTTCATTAAATATCGCACAAAACGTAGCGACGAAAACAGATGAAAATGTAGCGATTTTTAGTCTA
GAGATGGGTGCTGATCAGCTTGTTATGCGTATGCTATGTGCAGAAGGAAATATTGATGCGCAAAGACTTCGTACTGGATC
ATTAACTTCTGATGATTGGGCGAAATTAACGATGGCAATGGGTAGCCTTTCTAATGCTGGAATCTATATTGATGATACGC
CGGGGATTAAAGTAAATGAGATTCGAGCAAAATGTCGTAGATTAAAACAAGAACAGGGTCTTGGTATGATCTTGATTGAC
TACTTGCAGCTTATTCAAGGAAGTGGGAAATCAGGAGAGAACCGTCAGCAGGAAGTATCTGAGATTTCTCGTACACTAAA
AGGGATTGCGCGTGAATTACAAGTGCCTGTTATTGCCTTGTCACAGTTATCTCGTGGTGTAGAATCTCGTCAAGATAAAC
GTCCGATGATGTCTGATATTCGTGAATCGGGAAGTATCGAGCAGGATGCTGATATTGTAGCCTTTCTATATCGTGAGGAT
TACTATGACCGAGAAACGGAAAATAAAAATACGATTGAAATTATTATTGCAAAGCAGCGTAATGGTCCAGTAGGCTCAGT
AGAGCTTGCATTCGTTAAGGAGTTCAATAAGTTCGTTAACTTAGAACGTCGCTTCGAAGATGGACATGCACCGCCGGCAT
AA

Upstream 100 bases:

>100_bases
CTATACAAATGTTACTGTGAAATTGCATCCGCAAGTAACAGCAACAGTAAAAGTTCATGTTAGTGAACAATAAAAATACG
TTAAGCAAGGAGGATTGCGT

Downstream 100 bases:

>100_bases
AGATAGTATAAAAAAGAAACGCATTTCTTATAATAAGATGTGTTTCTTTTTTTTTATATAAAAGATAAGGCTTTCATAAT
GTAAAAATATAATTCTTACG

Product: replicative DNA helicase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 453; Mature: 452

Protein sequence:

>453_residues
MSDVMADRTPPHNIEAEQAVLGAILIDQDALTSASELLVPDSFYRTKHQKIFEVMLGLSDKGEPIDLVMMTSAMADQGLL
EEVGGVSYLAELAEVVPTAANVEYYARIIAEKALLRRLIRTATHIVSDGYEREDDVDGLLNEAEKKILEVSHQTNAKAFQ
NIKDVLVDAYDKIELLHNQKGEVTGIPTGFTELDKMTAGFQRNDLIIVAARPSVGKTAFSLNIAQNVATKTDENVAIFSL
EMGADQLVMRMLCAEGNIDAQRLRTGSLTSDDWAKLTMAMGSLSNAGIYIDDTPGIKVNEIRAKCRRLKQEQGLGMILID
YLQLIQGSGKSGENRQQEVSEISRTLKGIARELQVPVIALSQLSRGVESRQDKRPMMSDIRESGSIEQDADIVAFLYRED
YYDRETENKNTIEIIIAKQRNGPVGSVELAFVKEFNKFVNLERRFEDGHAPPA

Sequences:

>Translated_453_residues
MSDVMADRTPPHNIEAEQAVLGAILIDQDALTSASELLVPDSFYRTKHQKIFEVMLGLSDKGEPIDLVMMTSAMADQGLL
EEVGGVSYLAELAEVVPTAANVEYYARIIAEKALLRRLIRTATHIVSDGYEREDDVDGLLNEAEKKILEVSHQTNAKAFQ
NIKDVLVDAYDKIELLHNQKGEVTGIPTGFTELDKMTAGFQRNDLIIVAARPSVGKTAFSLNIAQNVATKTDENVAIFSL
EMGADQLVMRMLCAEGNIDAQRLRTGSLTSDDWAKLTMAMGSLSNAGIYIDDTPGIKVNEIRAKCRRLKQEQGLGMILID
YLQLIQGSGKSGENRQQEVSEISRTLKGIARELQVPVIALSQLSRGVESRQDKRPMMSDIRESGSIEQDADIVAFLYRED
YYDRETENKNTIEIIIAKQRNGPVGSVELAFVKEFNKFVNLERRFEDGHAPPA
>Mature_452_residues
SDVMADRTPPHNIEAEQAVLGAILIDQDALTSASELLVPDSFYRTKHQKIFEVMLGLSDKGEPIDLVMMTSAMADQGLLE
EVGGVSYLAELAEVVPTAANVEYYARIIAEKALLRRLIRTATHIVSDGYEREDDVDGLLNEAEKKILEVSHQTNAKAFQN
IKDVLVDAYDKIELLHNQKGEVTGIPTGFTELDKMTAGFQRNDLIIVAARPSVGKTAFSLNIAQNVATKTDENVAIFSLE
MGADQLVMRMLCAEGNIDAQRLRTGSLTSDDWAKLTMAMGSLSNAGIYIDDTPGIKVNEIRAKCRRLKQEQGLGMILIDY
LQLIQGSGKSGENRQQEVSEISRTLKGIARELQVPVIALSQLSRGVESRQDKRPMMSDIRESGSIEQDADIVAFLYREDY
YDRETENKNTIEIIIAKQRNGPVGSVELAFVKEFNKFVNLERRFEDGHAPPA

Specific function: Participates In Initiation And Elongation During Chromosome Replication; It Exhibits DNA-Dependent ATPase Activity And Contains Distinct Active Sites For ATP Binding, DNA Binding, And Interaction With DNAc Protein, Primase, And Other Prepriming Proteins.

COG id: COG0305

COG function: function code L; Replicative DNA helicase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 SF4 helicase domain [H]

Homologues:

Organism=Escherichia coli, GI1790486, Length=439, Percent_Identity=45.3302961275626, Blast_Score=390, Evalue=1e-109,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR007692
- InterPro:   IPR007694
- InterPro:   IPR007693
- InterPro:   IPR016136 [H]

Pfam domain/function: PF00772 DnaB; PF03796 DnaB_C [H]

EC number: =3.6.4.12 [H]

Molecular weight: Translated: 50196; Mature: 50065

Theoretical pI: Translated: 4.63; Mature: 4.63

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSDVMADRTPPHNIEAEQAVLGAILIDQDALTSASELLVPDSFYRTKHQKIFEVMLGLSD
CCCCCCCCCCCCCCCHHHHHHHHHEECCHHHCCHHHHCCCCHHHHHHHHHHHHHHHCCCC
KGEPIDLVMMTSAMADQGLLEEVGGVSYLAELAEVVPTAANVEYYARIIAEKALLRRLIR
CCCCEEEEEEHHHHHHHHHHHHHCHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHH
TATHIVSDGYEREDDVDGLLNEAEKKILEVSHQTNAKAFQNIKDVLVDAYDKIELLHNQK
HHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHCCC
GEVTGIPTGFTELDKMTAGFQRNDLIIVAARPSVGKTAFSLNIAQNVATKTDENVAIFSL
CCEECCCCCHHHHHHHHCCCCCCCEEEEEECCCCCCCEEEEEHHHHHHCCCCCCEEEEEE
EMGADQLVMRMLCAEGNIDAQRLRTGSLTSDDWAKLTMAMGSLSNAGIYIDDTPGIKVNE
ECCHHHHHHHHHHCCCCCCHHHHCCCCCCCHHHHHHHHHHHCCCCCCEEEECCCCCCHHH
IRAKCRRLKQEQGLGMILIDYLQLIQGSGKSGENRQQEVSEISRTLKGIARELQVPVIAL
HHHHHHHHHHHCCCCHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHCCHHHHH
SQLSRGVESRQDKRPMMSDIRESGSIEQDADIVAFLYREDYYDRETENKNTIEIIIAKQR
HHHHHHHHHHHCCCHHHHHHHHCCCCCCCCHHHHHHHHHHCCCCCCCCCCEEEEEEEECC
NGPVGSVELAFVKEFNKFVNLERRFEDGHAPPA
CCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCC
>Mature Secondary Structure 
SDVMADRTPPHNIEAEQAVLGAILIDQDALTSASELLVPDSFYRTKHQKIFEVMLGLSD
CCCCCCCCCCCCCCHHHHHHHHHEECCHHHCCHHHHCCCCHHHHHHHHHHHHHHHCCCC
KGEPIDLVMMTSAMADQGLLEEVGGVSYLAELAEVVPTAANVEYYARIIAEKALLRRLIR
CCCCEEEEEEHHHHHHHHHHHHHCHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHH
TATHIVSDGYEREDDVDGLLNEAEKKILEVSHQTNAKAFQNIKDVLVDAYDKIELLHNQK
HHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHCCC
GEVTGIPTGFTELDKMTAGFQRNDLIIVAARPSVGKTAFSLNIAQNVATKTDENVAIFSL
CCEECCCCCHHHHHHHHCCCCCCCEEEEEECCCCCCCEEEEEHHHHHHCCCCCCEEEEEE
EMGADQLVMRMLCAEGNIDAQRLRTGSLTSDDWAKLTMAMGSLSNAGIYIDDTPGIKVNE
ECCHHHHHHHHHHCCCCCCHHHHCCCCCCCHHHHHHHHHHHCCCCCCEEEECCCCCCHHH
IRAKCRRLKQEQGLGMILIDYLQLIQGSGKSGENRQQEVSEISRTLKGIARELQVPVIAL
HHHHHHHHHHHCCCCHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHCCHHHHH
SQLSRGVESRQDKRPMMSDIRESGSIEQDADIVAFLYREDYYDRETENKNTIEIIIAKQR
HHHHHHHHHHHCCCHHHHHHHHCCCCCCCCHHHHHHHHHHCCCCCCCCCCEEEEEEEECC
NGPVGSVELAFVKEFNKFVNLERRFEDGHAPPA
CCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7584024; 9384377; 1312531 [H]