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The map label for this gene is rlmH [H]

Identifier: 218906651

GI number: 218906651

Start: 5274175

End: 5274678

Strand: Reverse

Name: rlmH [H]

Synonym: BCAH820_5565

Alternate gene names: 218906651

Gene position: 5274678-5274175 (Counterclockwise)

Preceding gene: 218906652

Following gene: 218906650

Centisome position: 99.47

GC content: 33.33

Gene sequence:

>504_bases
ATGTTTGTAAGGTGGGGAATACGTGTGAATATCTCGATTATTTCAATTGGGAAATTAAAAGAAAAATATTTAAAACAAGG
TATAGCAGAATACTTAAAACGATTATCTGCATACGCAAAAGTAGAAGTAATTGAATTGCCAGATGAAAAGGCACCAGAAA
ATTTAAGTGAAGCAGAAATGTTAATTGTAAAAGAAAAAGAAGGTATCCGTATACTGGATAAAATTTCTGATGATACGCAT
GTGATCGCGTTAGCGATAGAAGGAAAACAAAAATCATCAGAAGAATTTGCAGTAAGTTTAGATCGTCTTGCTACATATGG
GAAGAGTAAAGTTGCATTCGTAATTGGTGGATCACTTGGACTAAGTTCAGAAGTAATGAAGCGTTCAAATGAATCTCTTT
CTTTTTCAAAAATGACATTACCACATCAATTAATGCGATTAGTGTTACTTGAGCAAGTGTATAGGGCATTTCGTATTAAT
CGTGGTGAACCGTATCACAAATGA

Upstream 100 bases:

>100_bases
AATTTTGTCAAAATGAGGCGACATATGTTGTATCGAACACAGATTCTCACACAATATGTGGGTAACAATTGTGGATATGT
GGATAAGTTATGTGGATAAC

Downstream 100 bases:

>100_bases
TGGTAAACATGAAAGTGGAATTGTTAGAACAAATAAGAAAACAAGTGAAACCATAGAGAATTAAGATAGATTTTTGACAG
ATAAACGAAATGCTTTTTTG

Product: rRNA large subunit methyltransferase

Products: NA

Alternate protein names: 23S rRNA m3Psi1915 methyltransferase; rRNA (pseudouridine-N3-)-methyltransferase rlmH [H]

Number of amino acids: Translated: 167; Mature: 167

Protein sequence:

>167_residues
MFVRWGIRVNISIISIGKLKEKYLKQGIAEYLKRLSAYAKVEVIELPDEKAPENLSEAEMLIVKEKEGIRILDKISDDTH
VIALAIEGKQKSSEEFAVSLDRLATYGKSKVAFVIGGSLGLSSEVMKRSNESLSFSKMTLPHQLMRLVLLEQVYRAFRIN
RGEPYHK

Sequences:

>Translated_167_residues
MFVRWGIRVNISIISIGKLKEKYLKQGIAEYLKRLSAYAKVEVIELPDEKAPENLSEAEMLIVKEKEGIRILDKISDDTH
VIALAIEGKQKSSEEFAVSLDRLATYGKSKVAFVIGGSLGLSSEVMKRSNESLSFSKMTLPHQLMRLVLLEQVYRAFRIN
RGEPYHK
>Mature_167_residues
MFVRWGIRVNISIISIGKLKEKYLKQGIAEYLKRLSAYAKVEVIELPDEKAPENLSEAEMLIVKEKEGIRILDKISDDTH
VIALAIEGKQKSSEEFAVSLDRLATYGKSKVAFVIGGSLGLSSEVMKRSNESLSFSKMTLPHQLMRLVLLEQVYRAFRIN
RGEPYHK

Specific function: Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA [H]

COG id: COG1576

COG function: function code S; Uncharacterized conserved protein

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the RNA methyltransferase rlmH family [H]

Homologues:

Organism=Escherichia coli, GI1786855, Length=159, Percent_Identity=30.8176100628931, Blast_Score=90, Evalue=6e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016051
- InterPro:   IPR003742 [H]

Pfam domain/function: PF02590 SPOUT_MTase [H]

EC number: NA

Molecular weight: Translated: 18941; Mature: 18941

Theoretical pI: Translated: 9.87; Mature: 9.87

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFVRWGIRVNISIISIGKLKEKYLKQGIAEYLKRLSAYAKVEVIELPDEKAPENLSEAEM
CEEEECEEEEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHEEEEEECCCCCCCCCCCCCEE
LIVKEKEGIRILDKISDDTHVIALAIEGKQKSSEEFAVSLDRLATYGKSKVAFVIGGSLG
EEEECCCCCEEEECCCCCCEEEEEEEECCCCCCHHHHHHHHHHHHCCCCEEEEEEECCCC
LSSEVMKRSNESLSFSKMTLPHQLMRLVLLEQVYRAFRINRGEPYHK
CCHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCC
>Mature Secondary Structure
MFVRWGIRVNISIISIGKLKEKYLKQGIAEYLKRLSAYAKVEVIELPDEKAPENLSEAEM
CEEEECEEEEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHEEEEEECCCCCCCCCCCCCEE
LIVKEKEGIRILDKISDDTHVIALAIEGKQKSSEEFAVSLDRLATYGKSKVAFVIGGSLG
EEEECCCCCEEEECCCCCCEEEEEEEECCCCCCHHHHHHHHHHHHCCCCEEEEEEECCCC
LSSEVMKRSNESLSFSKMTLPHQLMRLVLLEQVYRAFRINRGEPYHK
CCHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA