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The map label for this gene is tmk [H]

Identifier: 218906650

GI number: 218906650

Start: 5272936

End: 5273922

Strand: Reverse

Name: tmk [H]

Synonym: BCAH820_5564

Alternate gene names: 218906650

Gene position: 5273922-5272936 (Counterclockwise)

Preceding gene: 218906651

Following gene: 218906649

Centisome position: 99.46

GC content: 30.09

Gene sequence:

>987_bases
ATGAGTTCATTATTAAATATTATTGAAAAGTTTCAGTATAGGGAAGATTTCTTTTTGGATACTGAGGATTTACCTGAGAA
ATTAATAAATAAATTATTAAAATGGTATGATGGAAATCCTTATAATAAGTCAGATAAAAGAATAAAAGATGCATTTCATA
TTCTTTCATGGTGCTATGATAAATCGGATATAGATTATTTACCTCGAGATATGAGAGCGAAGCGATTTGAAGCAGCAGCA
CAGGCTTTAAACATATCTCATGAAAAATTAGTAAAGCTTTTTAATTCTCACACAAAAGTTTTGTTCCCTGGTCCAAAAGA
AACAAAGATAATTGCAGTTGAAGGTATTGATGGTAGTGGAAAAACAGTTCAAATGTCTTTACTAGAGGAACAGCTTAAGG
AAAAGGATAAACAGGTAATAATAAAATCCTTCCCTGTTTACGATAGCTTTTTTGGGAAAAATATTGGACAATTTTTATCG
GGAAACGAAGAGGTTAATGCAAACAATGTAGATCCTAAATCAATGTCTTTATGGTATGCTTTAGATAGATGGAAAGAATT
TGAAAACTTTAATTATATTAATTATGATTATTTATTATTGAATCGATTTACGCTTTCAAGTGCTGTATATCAAAGCTCTA
GGGTAGAACCAGAATTAAGAGAAGAATTTATACAATGGATATTTGAGTTAGAGCATTCCCAATTAGGATTACCCTCTCCA
GATTTATACATAGTTTTCGATCTTAATGCAGAAACTTCTAAAAAAAATGTATCAAATAAAGGATTTCGGGATTATGTGGG
AGAAAAAGCGGATGTATATGAAGAATCTGCTGATATAATGAGTAACGCAAGGGGAATTTATCAAGATTTAGCGAAAAAAT
ATAATAACATTGTTATTATTAATTGTTTGGACGAAAACAACAAGATGAAAACACCGGAAGAAATCAATCAAATTGTGATG
AAGGTGATAGAAGATGGGGAATATTAA

Upstream 100 bases:

>100_bases
ATATATATTTTATTATTATTAGTCAATCTTTTACCTTATAATGAGGATAAGATAAAAGAATTGTATAAAGGTATACAAAG
TTCAAAAAGGTGGTACAAAA

Downstream 100 bases:

>100_bases
GTACGATTCAGATTTAAACGAGTTTTATAGTTCAGGTAGTGATGAAGTATCAATTTTACCACAAATTATATGGCATATTA
CGGACAGGTGTTTTTTATCC

Product: thymidylate kinase, putative

Products: NA

Alternate protein names: Thymidine monophosphate kinase; dTMP kinase; TMPK [H]

Number of amino acids: Translated: 328; Mature: 327

Protein sequence:

>328_residues
MSSLLNIIEKFQYREDFFLDTEDLPEKLINKLLKWYDGNPYNKSDKRIKDAFHILSWCYDKSDIDYLPRDMRAKRFEAAA
QALNISHEKLVKLFNSHTKVLFPGPKETKIIAVEGIDGSGKTVQMSLLEEQLKEKDKQVIIKSFPVYDSFFGKNIGQFLS
GNEEVNANNVDPKSMSLWYALDRWKEFENFNYINYDYLLLNRFTLSSAVYQSSRVEPELREEFIQWIFELEHSQLGLPSP
DLYIVFDLNAETSKKNVSNKGFRDYVGEKADVYEESADIMSNARGIYQDLAKKYNNIVIINCLDENNKMKTPEEINQIVM
KVIEDGEY

Sequences:

>Translated_328_residues
MSSLLNIIEKFQYREDFFLDTEDLPEKLINKLLKWYDGNPYNKSDKRIKDAFHILSWCYDKSDIDYLPRDMRAKRFEAAA
QALNISHEKLVKLFNSHTKVLFPGPKETKIIAVEGIDGSGKTVQMSLLEEQLKEKDKQVIIKSFPVYDSFFGKNIGQFLS
GNEEVNANNVDPKSMSLWYALDRWKEFENFNYINYDYLLLNRFTLSSAVYQSSRVEPELREEFIQWIFELEHSQLGLPSP
DLYIVFDLNAETSKKNVSNKGFRDYVGEKADVYEESADIMSNARGIYQDLAKKYNNIVIINCLDENNKMKTPEEINQIVM
KVIEDGEY
>Mature_327_residues
SSLLNIIEKFQYREDFFLDTEDLPEKLINKLLKWYDGNPYNKSDKRIKDAFHILSWCYDKSDIDYLPRDMRAKRFEAAAQ
ALNISHEKLVKLFNSHTKVLFPGPKETKIIAVEGIDGSGKTVQMSLLEEQLKEKDKQVIIKSFPVYDSFFGKNIGQFLSG
NEEVNANNVDPKSMSLWYALDRWKEFENFNYINYDYLLLNRFTLSSAVYQSSRVEPELREEFIQWIFELEHSQLGLPSPD
LYIVFDLNAETSKKNVSNKGFRDYVGEKADVYEESADIMSNARGIYQDLAKKYNNIVIINCLDENNKMKTPEEINQIVMK
VIEDGEY

Specific function: Catalyzes the reversible phosphorylation of deoxythymidine monophosphate (dTMP) to deoxythymidine diphosphate (dTDP), using ATP as its preferred phosphoryl donor. Situated at the junction of both de novo and salvage pathways of deoxythymidine triphosphate

COG id: COG0125

COG function: function code F; Thymidylate kinase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the thymidylate kinase family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR018095
- InterPro:   IPR018094 [H]

Pfam domain/function: PF02223 Thymidylate_kin [H]

EC number: =2.7.4.9 [H]

Molecular weight: Translated: 38331; Mature: 38200

Theoretical pI: Translated: 4.78; Mature: 4.78

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSSLLNIIEKFQYREDFFLDTEDLPEKLINKLLKWYDGNPYNKSDKRIKDAFHILSWCYD
CHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHC
KSDIDYLPRDMRAKRFEAAAQALNISHEKLVKLFNSHTKVLFPGPKETKIIAVEGIDGSG
CCCCCCCCHHHHHHHHHHHHHHHCCCHHHHHHHHCCCCEEEECCCCCCEEEEEECCCCCC
KTVQMSLLEEQLKEKDKQVIIKSFPVYDSFFGKNIGQFLSGNEEVNANNVDPKSMSLWYA
CEEEHHHHHHHHHHHHHHEEHHHCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHH
LDRWKEFENFNYINYDYLLLNRFTLSSAVYQSSRVEPELREEFIQWIFELEHSQLGLPSP
HHHHHHHCCCCCCEEHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCCCC
DLYIVFDLNAETSKKNVSNKGFRDYVGEKADVYEESADIMSNARGIYQDLAKKYNNIVII
CEEEEEECCCCCCCCCCCCCCHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEE
NCLDENNKMKTPEEINQIVMKVIEDGEY
EEECCCCCCCCHHHHHHHHHHHHHCCCC
>Mature Secondary Structure 
SSLLNIIEKFQYREDFFLDTEDLPEKLINKLLKWYDGNPYNKSDKRIKDAFHILSWCYD
HHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHC
KSDIDYLPRDMRAKRFEAAAQALNISHEKLVKLFNSHTKVLFPGPKETKIIAVEGIDGSG
CCCCCCCCHHHHHHHHHHHHHHHCCCHHHHHHHHCCCCEEEECCCCCCEEEEEECCCCCC
KTVQMSLLEEQLKEKDKQVIIKSFPVYDSFFGKNIGQFLSGNEEVNANNVDPKSMSLWYA
CEEEHHHHHHHHHHHHHHEEHHHCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHH
LDRWKEFENFNYINYDYLLLNRFTLSSAVYQSSRVEPELREEFIQWIFELEHSQLGLPSP
HHHHHHHCCCCCCEEHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCCCC
DLYIVFDLNAETSKKNVSNKGFRDYVGEKADVYEESADIMSNARGIYQDLAKKYNNIVII
CEEEEEECCCCCCCCCCCCCCHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEE
NCLDENNKMKTPEEINQIVMKVIEDGEY
EEECCCCCCCCHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9634230; 12218036; 11369858; 10666613; 11469859; 11914484; 12454011; 12662932 [H]