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The map label for this gene is cisA [H]

Identifier: 218906639

GI number: 218906639

Start: 5262655

End: 5264202

Strand: Reverse

Name: cisA [H]

Synonym: BCAH820_5553

Alternate gene names: 218906639

Gene position: 5264202-5262655 (Counterclockwise)

Preceding gene: 218906640

Following gene: 218906638

Centisome position: 99.27

GC content: 30.23

Gene sequence:

>1548_bases
ATGAATAAGAAGGTAAAGGCAGGAATTTATATAAGGGTATCAACAGAGGAGCAAAAACAAGGTCATTCATTAGAAGCACA
AGAAAGCATGCTAAAGGAATTTGCAGATAGAAAGGGTTATGAAATATATGATGTATATAATGACGGTGGATATTCAGGAA
AGAATTTTAATAGACCTGAAATTCAAAGGTTATTAAGGGATTTAAAGGATGATAAAATTGATGTGATTTTAGTATGGAAG
GTTGATCGATTATCCCGTAATAATACTGATGTTATGTCACTAATAGATACTGAATTAACACCAAGGAAGAAGAATTTGAT
TATTACTTCCATTGATATGGATTCATCTTCACCGACAGGACATATGTTTATATCCTTACTTAGTACATTTGCAAGGTACG
AAAGGGCAACTATTATAGACCGTGTAAAAGCAGGAATGCAAAAGAGAGCCGAAAAAGGCTACTGGAATGGTGGCTCAATT
TTAGGATATGATTCAGTAGATAAAAAGTTAATTATTAATGAGAATGAGAGTGAAATTGTTAGAGAAATATTTCAACTTAG
AGCAGAAGGGAAAGGATACAAATTTATAGTTAATATCTTAAATGAAAAGGGGATTAAAACTAAGACAGGTAAAAACTTCA
GTATTCCAGCAATTAAAGTAATTGTTAATAATCATATATATAATGGTAAGATGGTATGGAAAAAACATCAAGACTGGAAT
ACAAGGAGGAGAACAGGAAAGTCAGAGCCTATAATTGTAGAAGGTATACATGATGCTATTATAGATGAGGGGTTATGGAC
GAGGGTACAAAAAGTTAATGAGCTCCAAAAGAATTCATTCTCTTCTAATAGAAATTTTAATGGAAACTTTCTTTTAACTG
GAATACTAAAATGCCCCAAATGCGGGGCGGGTACTGTTATGAGTAAAACAAAAAAGAGAAATAGTGATGATTACCATCTA
TATTATATGTGTCAAGCTTATCACAATAAGGGATCAAGTGTATGTAGCGCAAATTTAATAAGAAAAGACCAAGTTGAACA
ACAAGTATTAAATATAATATCACTTTTAGTGAATGAAAATGATATTATAAATGCATTGATAGATGAATTGAATAGTGATA
ATAATAAAACTAATGAGTCACATATAGCACATATAAAAATGTTAAAAAAACAACTTGGCAAAGCATATGACAAACGTAAA
AAATTGGATAATGATTACTTTGAGGGAAATATAGAAGGTAGTACTTATAATCGATTAATGAACGAGCTACAGTTAGATAT
TAATAAATTAAAAAGAAATGTTAGAGAATCTGAGAGTGAAATTATAAAAAATGACTCTACGATAAACAAAGAAGAAGTAA
TATATGCTCTTGAAAATTTTAATAAGCTCTTTAAGATAGTAAATGATGAAGAAAAAAAGTTACTTATAAGGTCTTTAATT
AGAGAAGTTCAAATGGAAGCGAATCGGAAAGATGTAAAAGAAATAACCTTCTGGTTTTTACCCAGTAGTGTTTTACCATC
TAATAAAGTGCGCAGAACCGTATCATAA

Upstream 100 bases:

>100_bases
AAAGAATGAAGCAATTAAAGTAATGGCACAGCTTATCAGAAAGTATATGGAGGAATTAACAAAAGAAGGATAGGATTAAA
TATTAAGGGAAGGGAAAAAA

Downstream 100 bases:

>100_bases
GTAAAATTACTTTTTGCATATAAAAAGAGTAAAAAAGACCATTGGACAAAAATCACCGATGGTCTTTTACACATTAATAG
GTGTTATATAGATTTCCTAA

Product: resolvase domain protein

Products: NA

Alternate protein names: Stage IV sporulation protein CA [H]

Number of amino acids: Translated: 515; Mature: 515

Protein sequence:

>515_residues
MNKKVKAGIYIRVSTEEQKQGHSLEAQESMLKEFADRKGYEIYDVYNDGGYSGKNFNRPEIQRLLRDLKDDKIDVILVWK
VDRLSRNNTDVMSLIDTELTPRKKNLIITSIDMDSSSPTGHMFISLLSTFARYERATIIDRVKAGMQKRAEKGYWNGGSI
LGYDSVDKKLIINENESEIVREIFQLRAEGKGYKFIVNILNEKGIKTKTGKNFSIPAIKVIVNNHIYNGKMVWKKHQDWN
TRRRTGKSEPIIVEGIHDAIIDEGLWTRVQKVNELQKNSFSSNRNFNGNFLLTGILKCPKCGAGTVMSKTKKRNSDDYHL
YYMCQAYHNKGSSVCSANLIRKDQVEQQVLNIISLLVNENDIINALIDELNSDNNKTNESHIAHIKMLKKQLGKAYDKRK
KLDNDYFEGNIEGSTYNRLMNELQLDINKLKRNVRESESEIIKNDSTINKEEVIYALENFNKLFKIVNDEEKKLLIRSLI
REVQMEANRKDVKEITFWFLPSSVLPSNKVRRTVS

Sequences:

>Translated_515_residues
MNKKVKAGIYIRVSTEEQKQGHSLEAQESMLKEFADRKGYEIYDVYNDGGYSGKNFNRPEIQRLLRDLKDDKIDVILVWK
VDRLSRNNTDVMSLIDTELTPRKKNLIITSIDMDSSSPTGHMFISLLSTFARYERATIIDRVKAGMQKRAEKGYWNGGSI
LGYDSVDKKLIINENESEIVREIFQLRAEGKGYKFIVNILNEKGIKTKTGKNFSIPAIKVIVNNHIYNGKMVWKKHQDWN
TRRRTGKSEPIIVEGIHDAIIDEGLWTRVQKVNELQKNSFSSNRNFNGNFLLTGILKCPKCGAGTVMSKTKKRNSDDYHL
YYMCQAYHNKGSSVCSANLIRKDQVEQQVLNIISLLVNENDIINALIDELNSDNNKTNESHIAHIKMLKKQLGKAYDKRK
KLDNDYFEGNIEGSTYNRLMNELQLDINKLKRNVRESESEIIKNDSTINKEEVIYALENFNKLFKIVNDEEKKLLIRSLI
REVQMEANRKDVKEITFWFLPSSVLPSNKVRRTVS
>Mature_515_residues
MNKKVKAGIYIRVSTEEQKQGHSLEAQESMLKEFADRKGYEIYDVYNDGGYSGKNFNRPEIQRLLRDLKDDKIDVILVWK
VDRLSRNNTDVMSLIDTELTPRKKNLIITSIDMDSSSPTGHMFISLLSTFARYERATIIDRVKAGMQKRAEKGYWNGGSI
LGYDSVDKKLIINENESEIVREIFQLRAEGKGYKFIVNILNEKGIKTKTGKNFSIPAIKVIVNNHIYNGKMVWKKHQDWN
TRRRTGKSEPIIVEGIHDAIIDEGLWTRVQKVNELQKNSFSSNRNFNGNFLLTGILKCPKCGAGTVMSKTKKRNSDDYHL
YYMCQAYHNKGSSVCSANLIRKDQVEQQVLNIISLLVNENDIINALIDELNSDNNKTNESHIAHIKMLKKQLGKAYDKRK
KLDNDYFEGNIEGSTYNRLMNELQLDINKLKRNVRESESEIIKNDSTINKEEVIYALENFNKLFKIVNDEEKKLLIRSLI
REVQMEANRKDVKEITFWFLPSSVLPSNKVRRTVS

Specific function: Putative site-specific recombinase having a very important role in sporulation. It probably plays a role in the recombination of spoIIIC and spoIVCB to form sigma K factor [H]

COG id: COG1961

COG function: function code L; Site-specific recombinases, DNA invertase Pin homologs

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 recombinase domain [H]

Homologues:

Organism=Escherichia coli, GI1787404, Length=148, Percent_Identity=31.7567567567568, Blast_Score=67, Evalue=3e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011109
- InterPro:   IPR006118
- InterPro:   IPR006119 [H]

Pfam domain/function: PF07508 Recombinase; PF00239 Resolvase [H]

EC number: NA

Molecular weight: Translated: 59523; Mature: 59523

Theoretical pI: Translated: 9.85; Mature: 9.85

Prosite motif: PS00397 RECOMBINASES_1 ; PS00290 IG_MHC

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNKKVKAGIYIRVSTEEQKQGHSLEAQESMLKEFADRKGYEIYDVYNDGGYSGKNFNRPE
CCCCEEEEEEEEEECCHHHCCCCCHHHHHHHHHHHHCCCCEEEEEECCCCCCCCCCCCHH
IQRLLRDLKDDKIDVILVWKVDRLSRNNTDVMSLIDTELTPRKKNLIITSIDMDSSSPTG
HHHHHHHCCCCCCCEEEEEEEHHCCCCCCHHHHHHHCCCCCCCCCEEEEEEECCCCCCHH
HMFISLLSTFARYERATIIDRVKAGMQKRAEKGYWNGGSILGYDSVDKKLIINENESEIV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEECCCCCCEEEEECCHHHHH
REIFQLRAEGKGYKFIVNILNEKGIKTKTGKNFSIPAIKVIVNNHIYNGKMVWKKHQDWN
HHHHHHHCCCCCCEEEEEEHHCCCCCCCCCCCCCCCEEEEEEECEEECCEEEEEECCCCC
TRRRTGKSEPIIVEGIHDAIIDEGLWTRVQKVNELQKNSFSSNRNFNGNFLLTGILKCPK
HHHHCCCCCCEEEECHHHHHHCCHHHHHHHHHHHHHHHCCCCCCCCCCCEEEEEECCCCC
CGAGTVMSKTKKRNSDDYHLYYMCQAYHNKGSSVCSANLIRKDQVEQQVLNIISLLVNEN
CCCCHHHHHHHCCCCCCEEEEEEEEEHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCC
DIINALIDELNSDNNKTNESHIAHIKMLKKQLGKAYDKRKKLDNDYFEGNIEGSTYNRLM
HHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHH
NELQLDINKLKRNVRESESEIIKNDSTINKEEVIYALENFNKLFKIVNDEEKKLLIRSLI
HHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHH
REVQMEANRKDVKEITFWFLPSSVLPSNKVRRTVS
HHHHHHCCHHHHHHHHHHCCCCCCCCCHHHHCCCC
>Mature Secondary Structure
MNKKVKAGIYIRVSTEEQKQGHSLEAQESMLKEFADRKGYEIYDVYNDGGYSGKNFNRPE
CCCCEEEEEEEEEECCHHHCCCCCHHHHHHHHHHHHCCCCEEEEEECCCCCCCCCCCCHH
IQRLLRDLKDDKIDVILVWKVDRLSRNNTDVMSLIDTELTPRKKNLIITSIDMDSSSPTG
HHHHHHHCCCCCCCEEEEEEEHHCCCCCCHHHHHHHCCCCCCCCCEEEEEEECCCCCCHH
HMFISLLSTFARYERATIIDRVKAGMQKRAEKGYWNGGSILGYDSVDKKLIINENESEIV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEECCCCCCEEEEECCHHHHH
REIFQLRAEGKGYKFIVNILNEKGIKTKTGKNFSIPAIKVIVNNHIYNGKMVWKKHQDWN
HHHHHHHCCCCCCEEEEEEHHCCCCCCCCCCCCCCCEEEEEEECEEECCEEEEEECCCCC
TRRRTGKSEPIIVEGIHDAIIDEGLWTRVQKVNELQKNSFSSNRNFNGNFLLTGILKCPK
HHHHCCCCCCEEEECHHHHHHCCHHHHHHHHHHHHHHHCCCCCCCCCCCEEEEEECCCCC
CGAGTVMSKTKKRNSDDYHLYYMCQAYHNKGSSVCSANLIRKDQVEQQVLNIISLLVNEN
CCCCHHHHHHHCCCCCCEEEEEEEEEHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCC
DIINALIDELNSDNNKTNESHIAHIKMLKKQLGKAYDKRKKLDNDYFEGNIEGSTYNRLM
HHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHH
NELQLDINKLKRNVRESESEIIKNDSTINKEEVIYALENFNKLFKIVNDEEKKLLIRSLI
HHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHH
REVQMEANRKDVKEITFWFLPSSVLPSNKVRRTVS
HHHHHHCCHHHHHHHHHHCCCCCCCCCHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 2105293; 7704261; 8969508; 9384377 [H]