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The map label for this gene is pyrF [H]

Identifier: 218905013

GI number: 218905013

Start: 3734882

End: 3735598

Strand: Reverse

Name: pyrF [H]

Synonym: BCAH820_3897

Alternate gene names: 218905013

Gene position: 3735598-3734882 (Counterclockwise)

Preceding gene: 218905014

Following gene: 218905012

Centisome position: 70.45

GC content: 40.17

Gene sequence:

>717_bases
ATGTCACAGTCGTTAATCGTTGCACTAGATTTCCCAGGGAAACAAGATGTAGAACAATTCTTGCGCCACTTTGAAGGGGA
AGAGTTATTTGTCAAAGTTGGTATGGAGTTATTTTACAAAGAAGGCCCTGCGATTATTACGTACTTAAAAGAAAAAGGAC
ATAAAATCTTTCTAGATTTAAAACTTCATGATATTCCGAATACAGTAAAAAGCGCTATGCGTAGCCTAGCTAGTCTAGAT
GTAGATATGGTAAATGTTCATGCTGCTGGGGGAAGCAGTATGATGAAAGCTGCGATTGAGGGATTAGAGGAAGGTAAGCA
AGAAGGAAAAGAGAGACCGATTTGTATTGCAGTTACACAACTAACAAGCACTTCGGAAACTATGATGAAAAAAGAGATTG
GCATTGAGAAAACGTTAGAAGAAGCGGTTGCTCATTATGCAAAACTAACGAAAGAAAGTGGACTTGATGGCGTTGTTTGC
TCAACACTTGAAGTTCCAAAATTACGTGAAGTATGCGGAAGTGAATTTGTAACAGTAACACCGGGGATTCGTCTTGCAAG
CGATGATGTAAATGACCAGGTGCGCGTAGCAACACCGAAACGTGCGAGGGAACTTGGCTCAAGCTATATCGTAGTTGGAC
GTAGTATTACAAAAGCAGAAAATCCGCTTGAAGCGTATAAAACAGTAAAACAACAGTGGGAAGGTGTAACAGTATGA

Upstream 100 bases:

>100_bases
CGTTCGTATGTCCGACAATTATTGAGGAGTTACCAGCATTACTAGATGAATTAGGATTTGATCACATTTCGGAATGTCAA
GGAAGGAGCTGGAAGCAAAC

Downstream 100 bases:

>100_bases
AAAAAGAAATCGCATCGCATTTATTAGAAATTGGAGCAGTATTTTTACAACCAAATGATCCATTCACATGGTCTTCAGGT
ATGAAATCACCAATTTATTG

Product: orotidine 5'-phosphate decarboxylase

Products: NA

Alternate protein names: OMP decarboxylase; OMPDCase; OMPdecase [H]

Number of amino acids: Translated: 238; Mature: 237

Protein sequence:

>238_residues
MSQSLIVALDFPGKQDVEQFLRHFEGEELFVKVGMELFYKEGPAIITYLKEKGHKIFLDLKLHDIPNTVKSAMRSLASLD
VDMVNVHAAGGSSMMKAAIEGLEEGKQEGKERPICIAVTQLTSTSETMMKKEIGIEKTLEEAVAHYAKLTKESGLDGVVC
STLEVPKLREVCGSEFVTVTPGIRLASDDVNDQVRVATPKRARELGSSYIVVGRSITKAENPLEAYKTVKQQWEGVTV

Sequences:

>Translated_238_residues
MSQSLIVALDFPGKQDVEQFLRHFEGEELFVKVGMELFYKEGPAIITYLKEKGHKIFLDLKLHDIPNTVKSAMRSLASLD
VDMVNVHAAGGSSMMKAAIEGLEEGKQEGKERPICIAVTQLTSTSETMMKKEIGIEKTLEEAVAHYAKLTKESGLDGVVC
STLEVPKLREVCGSEFVTVTPGIRLASDDVNDQVRVATPKRARELGSSYIVVGRSITKAENPLEAYKTVKQQWEGVTV
>Mature_237_residues
SQSLIVALDFPGKQDVEQFLRHFEGEELFVKVGMELFYKEGPAIITYLKEKGHKIFLDLKLHDIPNTVKSAMRSLASLDV
DMVNVHAAGGSSMMKAAIEGLEEGKQEGKERPICIAVTQLTSTSETMMKKEIGIEKTLEEAVAHYAKLTKESGLDGVVCS
TLEVPKLREVCGSEFVTVTPGIRLASDDVNDQVRVATPKRARELGSSYIVVGRSITKAENPLEAYKTVKQQWEGVTV

Specific function: Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP) [H]

COG id: COG0284

COG function: function code F; Orotidine-5'-phosphate decarboxylase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the OMP decarboxylase family. Type 1 subfamily [H]

Homologues:

Organism=Escherichia coli, GI1787537, Length=226, Percent_Identity=40.7079646017699, Blast_Score=167, Evalue=5e-43,

Paralogues:

None

Copy number: 6,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013785
- InterPro:   IPR014732
- InterPro:   IPR018089
- InterPro:   IPR001754
- InterPro:   IPR011060 [H]

Pfam domain/function: PF00215 OMPdecase [H]

EC number: =4.1.1.23 [H]

Molecular weight: Translated: 26202; Mature: 26070

Theoretical pI: Translated: 5.73; Mature: 5.73

Prosite motif: PS00156 OMPDECASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSQSLIVALDFPGKQDVEQFLRHFEGEELFVKVGMELFYKEGPAIITYLKEKGHKIFLDL
CCCCEEEEEECCCHHHHHHHHHHCCCCCEEHHHHHHHHHCCCCEEEEEEHHCCCEEEEEE
KLHDIPNTVKSAMRSLASLDVDMVNVHAAGGSSMMKAAIEGLEEGKQEGKERPICIAVTQ
EECCCCHHHHHHHHHHHHCCCEEEEEEECCCHHHHHHHHHHHHHHHHCCCCCCEEEEEEE
LTSTSETMMKKEIGIEKTLEEAVAHYAKLTKESGLDGVVCSTLEVPKLREVCGSEFVTVT
CCCHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCCCCEEECCCCCHHHHHHHCCCEEEEC
PGIRLASDDVNDQVRVATPKRARELGSSYIVVGRSITKAENPLEAYKTVKQQWEGVTV
CCCEEECCCCCCCEEEECCHHHHHCCCCEEEECCCHHCCCCHHHHHHHHHHHCCCCCC
>Mature Secondary Structure 
SQSLIVALDFPGKQDVEQFLRHFEGEELFVKVGMELFYKEGPAIITYLKEKGHKIFLDL
CCCEEEEEECCCHHHHHHHHHHCCCCCEEHHHHHHHHHCCCCEEEEEEHHCCCEEEEEE
KLHDIPNTVKSAMRSLASLDVDMVNVHAAGGSSMMKAAIEGLEEGKQEGKERPICIAVTQ
EECCCCHHHHHHHHHHHHCCCEEEEEEECCCHHHHHHHHHHHHHHHHCCCCCCEEEEEEE
LTSTSETMMKKEIGIEKTLEEAVAHYAKLTKESGLDGVVCSTLEVPKLREVCGSEFVTVT
CCCHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCCCCEEECCCCCHHHHHHHCCCEEEEC
PGIRLASDDVNDQVRVATPKRARELGSSYIVVGRSITKAENPLEAYKTVKQQWEGVTV
CCCEEECCCCCCCEEEECCHHHHHCCCCEEEECCCHHCCCCHHHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA