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The map label for this gene is appC [H]

Identifier: 218902116

GI number: 218902116

Start: 965091

End: 965942

Strand: Direct

Name: appC [H]

Synonym: BCAH820_0998

Alternate gene names: 218902116

Gene position: 965091-965942 (Clockwise)

Preceding gene: 218902115

Following gene: 218902117

Centisome position: 18.2

GC content: 37.37

Gene sequence:

>852_bases
ATGAATAATAGGAGATTTCAAACGATAAAGCATAGTTTTACAAAAAATAAGTTTGTTGCAATGGGAGTTATTATACTTGC
GGTTTTAACGGTCGCATCGATTTTCGCATTCGTATCGCCTTACGATCCTAGTAAAATGTCAATTCCAGATCGCTTACAAG
AACCAAGTGTGAGTTATCCTTTCGGAACGGATGATTACGGAAGAGATTACTTAACTAGGGCGTTATATGGTGGACGCGTT
TCACTTGCGGTTGGTTTCCTTGCRATGGTTGTATCTGTTACAATCGGTACCGCAGTTGGAACAATTAGCGGATATTTTGG
CGGAAAGTTAGACAACTTCTTAATGCGAGTTGTTGAAGTGCTTATGTCAATTCCATCATTCTTCTTAATGTTACTATTAA
ATGCTTATTTAAAACCAGGAATTACAACGTTAGTTCTTATTATCGGATTACTAACATGGATGGACACCGCTCGTATCGTA
AGGGCAGAGACTTTATCTGTAAAAGAGCGTGAGTACGTTTTATATGCAAAAGTGTCAGGACAAAAATCACTCACGATTAT
TGTAAGACATATCATTCCTAACATTTTATCAACCATTATTATCGCCGCGACATTAACAATTGCGACATCGATTTTAATGG
AATCATCACTTAGTTTCTTAGGTTTAGGTATTAGAGAACCAGATTCTTCTTGGGGCAGTATGCTAAACAATGCGCAAGGA
TATATTGGCGAAGCTTGGTATTTAACACTCTTCCCAGGATTCCTTATCCTTTTAACGGTACTAAGTTTTAACGTAATTGG
TGAAGCATTGAAGAAAGCTTTCGCACCAAAAGGAGCTGGAAATGAAAACTAA

Upstream 100 bases:

>100_bases
TACATTATTATCATCATTCATGTTGATTCTTGGTAACTTAATTGCTGATATTTTATATGGCGTAGTAGATCCGCGCATTC
GAATGAGGGGGTGATTTGGA

Downstream 100 bases:

>100_bases
AGTGTTAAGTGAAAGGAGGGAGAAGCGTGTCTGAAAAACTACTAGAAGTGAAAAATTTAAAGACTTCTTTTTTCATAGAA
AGTGGAGAAGTGGAAGCCGT

Product: oligopeptide ABC transporter, permease protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 283; Mature: 283

Protein sequence:

>283_residues
MNNRRFQTIKHSFTKNKFVAMGVIILAVLTVASIFAFVSPYDPSKMSIPDRLQEPSVSYPFGTDDYGRDYLTRALYGGRV
SLAVGFLAMVVSVTIGTAVGTISGYFGGKLDNFLMRVVEVLMSIPSFFLMLLLNAYLKPGITTLVLIIGLLTWMDTARIV
RAETLSVKEREYVLYAKVSGQKSLTIIVRHIIPNILSTIIIAATLTIATSILMESSLSFLGLGIREPDSSWGSMLNNAQG
YIGEAWYLTLFPGFLILLTVLSFNVIGEALKKAFAPKGAGNEN

Sequences:

>Translated_283_residues
MNNRRFQTIKHSFTKNKFVAMGVIILAVLTVASIFAFVSPYDPSKMSIPDRLQEPSVSYPFGTDDYGRDYLTRALYGGRV
SLAVGFLAMVVSVTIGTAVGTISGYFGGKLDNFLMRVVEVLMSIPSFFLMLLLNAYLKPGITTLVLIIGLLTWMDTARIV
RAETLSVKEREYVLYAKVSGQKSLTIIVRHIIPNILSTIIIAATLTIATSILMESSLSFLGLGIREPDSSWGSMLNNAQG
YIGEAWYLTLFPGFLILLTVLSFNVIGEALKKAFAPKGAGNEN
>Mature_283_residues
MNNRRFQTIKHSFTKNKFVAMGVIILAVLTVASIFAFVSPYDPSKMSIPDRLQEPSVSYPFGTDDYGRDYLTRALYGGRV
SLAVGFLAMVVSVTIGTAVGTISGYFGGKLDNFLMRVVEVLMSIPSFFLMLLLNAYLKPGITTLVLIIGLLTWMDTARIV
RAETLSVKEREYVLYAKVSGQKSLTIIVRHIIPNILSTIIIAATLTIATSILMESSLSFLGLGIREPDSSWGSMLNNAQG
YIGEAWYLTLFPGFLILLTVLSFNVIGEALKKAFAPKGAGNEN

Specific function: This protein is a component of an oligopeptide permease, a binding protein-dependent transport system. This APP system can completely substitute for the OPP system in both sporulation and genetic competence, though, unlike OPP, is incapable of transportin

COG id: COG1173

COG function: function code EP; ABC-type dipeptide/oligopeptide/nickel transport systems, permease components

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transmembrane type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI1787054, Length=279, Percent_Identity=36.5591397849462, Blast_Score=187, Evalue=8e-49,
Organism=Escherichia coli, GI1787760, Length=265, Percent_Identity=33.9622641509434, Blast_Score=181, Evalue=5e-47,
Organism=Escherichia coli, GI1787498, Length=278, Percent_Identity=38.4892086330935, Blast_Score=178, Evalue=4e-46,
Organism=Escherichia coli, GI1789964, Length=278, Percent_Identity=36.6906474820144, Blast_Score=161, Evalue=4e-41,
Organism=Escherichia coli, GI1789889, Length=238, Percent_Identity=33.1932773109244, Blast_Score=160, Evalue=6e-41,
Organism=Escherichia coli, GI1788505, Length=226, Percent_Identity=34.9557522123894, Blast_Score=130, Evalue=8e-32,
Organism=Escherichia coli, GI1787549, Length=275, Percent_Identity=28, Blast_Score=115, Evalue=3e-27,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000515 [H]

Pfam domain/function: PF00528 BPD_transp_1 [H]

EC number: NA

Molecular weight: Translated: 30986; Mature: 30986

Theoretical pI: Translated: 9.83; Mature: 9.83

Prosite motif: PS50928 ABC_TM1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNNRRFQTIKHSFTKNKFVAMGVIILAVLTVASIFAFVSPYDPSKMSIPDRLQEPSVSYP
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHCCCCCCCC
FGTDDYGRDYLTRALYGGRVSLAVGFLAMVVSVTIGTAVGTISGYFGGKLDNFLMRVVEV
CCCCCCCHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHH
LMSIPSFFLMLLLNAYLKPGITTLVLIIGLLTWMDTARIVRAETLSVKEREYVLYAKVSG
HHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEECC
QKSLTIIVRHIIPNILSTIIIAATLTIATSILMESSLSFLGLGIREPDSSWGSMLNNAQG
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHCCCC
YIGEAWYLTLFPGFLILLTVLSFNVIGEALKKAFAPKGAGNEN
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCC
>Mature Secondary Structure
MNNRRFQTIKHSFTKNKFVAMGVIILAVLTVASIFAFVSPYDPSKMSIPDRLQEPSVSYP
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHCCCCCCCC
FGTDDYGRDYLTRALYGGRVSLAVGFLAMVVSVTIGTAVGTISGYFGGKLDNFLMRVVEV
CCCCCCCHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHH
LMSIPSFFLMLLLNAYLKPGITTLVLIIGLLTWMDTARIVRAETLSVKEREYVLYAKVSG
HHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEECC
QKSLTIIVRHIIPNILSTIIIAATLTIATSILMESSLSFLGLGIREPDSSWGSMLNNAQG
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHCCCC
YIGEAWYLTLFPGFLILLTVLSFNVIGEALKKAFAPKGAGNEN
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 7997159; 9384377 [H]