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The map label for this gene is cdc6

Identifier: 218884688

GI number: 218884688

Start: 1279912

End: 1281096

Strand: Direct

Name: cdc6

Synonym: DKAM_1377

Alternate gene names: 218884688

Gene position: 1279912-1281096 (Clockwise)

Preceding gene: 218884663

Following gene: 218884689

Centisome position: 93.75

GC content: 45.15

Gene sequence:

>1185_bases
TTGGCTGATATCATCGACGAGCTCATTAGGAAGCGAGGATTTGCATCAAGGATATTTAGGAACAGAGAGGTCCTCCACCC
AGACTACATACCTGATACTCTGCCCCATAGAGAAAACGAGATCAGGAGGCTTGCAGAGCATCTTCTTGTTTCTGCACAGG
GTATGAGGCCCAGTAATGTCCTAATCTATGGTTTAACAGGTACTGGTAAAACCGTTGTGGTGAAGTATGTCGTATCCAAG
CTCAAGGAGAAGGCATCATCATTGAATAAGAGGCTTGACTACGCTTATGTTAACACGAGGAAGCTTGACACAACCTATAG
GGTGATAGCTAGTATAGCTCAAAGCATCGGGTTAAGGGTGCCTCACACCGGGCTAGCGATAAGTGAAGTATATAGAAGAT
ATATTAATGCGTTGGATAGCTGGGGAGGCCTCCACATAATCGTCTTAGACGAGGTGGATTACTATGTTAAGCGTGAAGGA
GATGATCTAATATACAAGCTTGTGAGAGCCAATGAGGAATTAAGCAAGGCTAAGATAGTCTTGATCGGTATAACAAACGA
CGTCAACTTCGTCGAGAACCTTGATCCAAGGGTTAGGTCTAGTATGGGGGAGATAGAGATGGTTTTCCCGCCATATAATG
CCGAGCAATTATTCACCATATTGAAGCAGAGGGCTGAACTAGCGTTCAATCAGGGCGTAATAGAGGATGGTGTGATATCA
TACTGTTCAGCCCTGGCTGCAAGAGAACACGGAGATGCCAGGAGAGCGCTGGATTTACTCAGAGTGTCCGGTGAAATAGC
TGAAAGAGAGGGTGCTGAGAGGGTTACAATAGAGTATGTGAAGAAAGCCACCCTTGAGATCGAGGAGGGCAGGATATACC
AGAGCGTCGTCACGCTACCTCTTCACCAGAAGCTCGTGTTGAAGAAGATAGTGGAGCTTGTTGAGGCCAAGGAATCCACG
ACAACCGGGGAAGTATATACAGCATACTCCAATATAATGAGGAACCTTAAATACGAGCCGCTCTCTCTGCGCAGGATCAG
TGAGATTATTTCACAACTAGATATGATGGGGCTGATTATCTCAGAGGTGGTTAATAGAGGCAAATATGGTATCACGAGGA
TAATAAAGATAAGAAAGGATATGCTCCCAGTCATTAAGGATGCATTAAAGGATGTTGAAGCATAG

Upstream 100 bases:

>100_bases
GCTCTCAGGGAAAAAATAAATATTTGAAGGGAGATATGGGATGTCTAGTATTATTTATAGCTATAGTGTTTAACCGTATC
AAAGCTTATGGGTGTGTATC

Downstream 100 bases:

>100_bases
CCCCCAAGTGTTTCATAATGACTAAACACTGTTGTATCATAGAGGCCTATGACGACGGGTTTTTCCCTCCCGAATTCAAG
GGCGGGAGGGGAGACACCTT

Product: cell division control protein 6-like protein, cdc6

Products: NA

Alternate protein names: CDC6 homolog

Number of amino acids: Translated: 394; Mature: 393

Protein sequence:

>394_residues
MADIIDELIRKRGFASRIFRNREVLHPDYIPDTLPHRENEIRRLAEHLLVSAQGMRPSNVLIYGLTGTGKTVVVKYVVSK
LKEKASSLNKRLDYAYVNTRKLDTTYRVIASIAQSIGLRVPHTGLAISEVYRRYINALDSWGGLHIIVLDEVDYYVKREG
DDLIYKLVRANEELSKAKIVLIGITNDVNFVENLDPRVRSSMGEIEMVFPPYNAEQLFTILKQRAELAFNQGVIEDGVIS
YCSALAAREHGDARRALDLLRVSGEIAEREGAERVTIEYVKKATLEIEEGRIYQSVVTLPLHQKLVLKKIVELVEAKEST
TTGEVYTAYSNIMRNLKYEPLSLRRISEIISQLDMMGLIISEVVNRGKYGITRIIKIRKDMLPVIKDALKDVEA

Sequences:

>Translated_394_residues
MADIIDELIRKRGFASRIFRNREVLHPDYIPDTLPHRENEIRRLAEHLLVSAQGMRPSNVLIYGLTGTGKTVVVKYVVSK
LKEKASSLNKRLDYAYVNTRKLDTTYRVIASIAQSIGLRVPHTGLAISEVYRRYINALDSWGGLHIIVLDEVDYYVKREG
DDLIYKLVRANEELSKAKIVLIGITNDVNFVENLDPRVRSSMGEIEMVFPPYNAEQLFTILKQRAELAFNQGVIEDGVIS
YCSALAAREHGDARRALDLLRVSGEIAEREGAERVTIEYVKKATLEIEEGRIYQSVVTLPLHQKLVLKKIVELVEAKEST
TTGEVYTAYSNIMRNLKYEPLSLRRISEIISQLDMMGLIISEVVNRGKYGITRIIKIRKDMLPVIKDALKDVEA
>Mature_393_residues
ADIIDELIRKRGFASRIFRNREVLHPDYIPDTLPHRENEIRRLAEHLLVSAQGMRPSNVLIYGLTGTGKTVVVKYVVSKL
KEKASSLNKRLDYAYVNTRKLDTTYRVIASIAQSIGLRVPHTGLAISEVYRRYINALDSWGGLHIIVLDEVDYYVKREGD
DLIYKLVRANEELSKAKIVLIGITNDVNFVENLDPRVRSSMGEIEMVFPPYNAEQLFTILKQRAELAFNQGVIEDGVISY
CSALAAREHGDARRALDLLRVSGEIAEREGAERVTIEYVKKATLEIEEGRIYQSVVTLPLHQKLVLKKIVELVEAKESTT
TGEVYTAYSNIMRNLKYEPLSLRRISEIISQLDMMGLIISEVVNRGKYGITRIIKIRKDMLPVIKDALKDVEA

Specific function: Might be involved in the initiation of DNA replication

COG id: COG1474

COG function: function code LO; Cdc6-related protein, AAA superfamily ATPase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the CDC6/cdc18 family

Homologues:

Organism=Homo sapiens, GI4502703, Length=337, Percent_Identity=26.7062314540059, Blast_Score=101, Evalue=1e-21,
Organism=Homo sapiens, GI299890795, Length=249, Percent_Identity=27.3092369477912, Blast_Score=72, Evalue=9e-13,
Organism=Homo sapiens, GI299890793, Length=249, Percent_Identity=27.3092369477912, Blast_Score=72, Evalue=9e-13,
Organism=Homo sapiens, GI31795544, Length=249, Percent_Identity=27.3092369477912, Blast_Score=72, Evalue=9e-13,
Organism=Caenorhabditis elegans, GI17555708, Length=342, Percent_Identity=24.8538011695906, Blast_Score=84, Evalue=9e-17,
Organism=Drosophila melanogaster, GI17137456, Length=368, Percent_Identity=25.8152173913043, Blast_Score=85, Evalue=1e-16,
Organism=Drosophila melanogaster, GI21355681, Length=240, Percent_Identity=25.8333333333333, Blast_Score=67, Evalue=3e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): CDC6_DESK1 (B8D6H2)

Other databases:

- EMBL:   CP001140
- RefSeq:   YP_002429070.1
- GeneID:   7171419
- GenomeReviews:   CP001140_GR
- KEGG:   dka:DKAM_1377
- HOGENOM:   HBG553472
- OMA:   IPMTGWP
- ProtClustDB:   CLSK2399579
- HAMAP:   MF_01407
- InterPro:   IPR003593
- InterPro:   IPR003959
- InterPro:   IPR015163
- InterPro:   IPR014277
- InterPro:   IPR011991
- Gene3D:   G3DSA:1.10.10.10
- PANTHER:   PTHR10763:SF8
- SMART:   SM00382
- TIGRFAMs:   TIGR02928

Pfam domain/function: PF00004 AAA; PF09079 Cdc6_C

EC number: NA

Molecular weight: Translated: 44775; Mature: 44643

Theoretical pI: Translated: 9.14; Mature: 9.14

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MADIIDELIRKRGFASRIFRNREVLHPDYIPDTLPHRENEIRRLAEHLLVSAQGMRPSNV
CHHHHHHHHHHCCHHHHHHCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCE
LIYGLTGTGKTVVVKYVVSKLKEKASSLNKRLDYAYVNTRKLDTTYRVIASIAQSIGLRV
EEEEECCCCHHHHHHHHHHHHHHHHHHHHHHCCHHEECCHHHHHHHHHHHHHHHHCCCCC
PHTGLAISEVYRRYINALDSWGGLHIIVLDEVDYYVKREGDDLIYKLVRANEELSKAKIV
CCCCHHHHHHHHHHHHHHHCCCCEEEEEEECCCHHHHCCCHHHHHHHHHCCCHHCCCEEE
LIGITNDVNFVENLDPRVRSSMGEIEMVFPPYNAEQLFTILKQRAELAFNQGVIEDGVIS
EEEECCCCHHHHCCCHHHHHCCCCEEEEECCCCHHHHHHHHHHHHHHHHHCCCCHHHHHH
YCSALAAREHGDARRALDLLRVSGEIAEREGAERVTIEYVKKATLEIEEGRIYQSVVTLP
HHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHEECCCHHHHHHHHHH
LHQKLVLKKIVELVEAKESTTTGEVYTAYSNIMRNLKYEPLSLRRISEIISQLDMMGLII
HHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHH
SEVVNRGKYGITRIIKIRKDMLPVIKDALKDVEA
HHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
ADIIDELIRKRGFASRIFRNREVLHPDYIPDTLPHRENEIRRLAEHLLVSAQGMRPSNV
HHHHHHHHHHCCHHHHHHCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCE
LIYGLTGTGKTVVVKYVVSKLKEKASSLNKRLDYAYVNTRKLDTTYRVIASIAQSIGLRV
EEEEECCCCHHHHHHHHHHHHHHHHHHHHHHCCHHEECCHHHHHHHHHHHHHHHHCCCCC
PHTGLAISEVYRRYINALDSWGGLHIIVLDEVDYYVKREGDDLIYKLVRANEELSKAKIV
CCCCHHHHHHHHHHHHHHHCCCCEEEEEEECCCHHHHCCCHHHHHHHHHCCCHHCCCEEE
LIGITNDVNFVENLDPRVRSSMGEIEMVFPPYNAEQLFTILKQRAELAFNQGVIEDGVIS
EEEECCCCHHHHCCCHHHHHCCCCEEEEECCCCHHHHHHHHHHHHHHHHHCCCCHHHHHH
YCSALAAREHGDARRALDLLRVSGEIAEREGAERVTIEYVKKATLEIEEGRIYQSVVTLP
HHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHEECCCHHHHHHHHHH
LHQKLVLKKIVELVEAKESTTTGEVYTAYSNIMRNLKYEPLSLRRISEIISQLDMMGLII
HHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHH
SEVVNRGKYGITRIIKIRKDMLPVIKDALKDVEA
HHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA