Click here to switch to the map view.

The map label for this gene is tgtA [H]

Identifier: 218884567

GI number: 218884567

Start: 1175571

End: 1176062

Strand: Direct

Name: tgtA [H]

Synonym: DKAM_1256

Alternate gene names: 218884567

Gene position: 1175571-1176062 (Clockwise)

Preceding gene: 218884566

Following gene: 218884568

Centisome position: 86.11

GC content: 43.09

Gene sequence:

>492_bases
GTGTACTCTATGGGCTTCATTAAGCGTAAACCCAGCGATAGGGAGCTAGATGAGTTAAGATGGATCGCTAAAATACAGTT
CGGCGTAGGCAGAGACTTCATACCCGACGACATAGATGTTGTTTTAAGCCGGAGCACTCTTAAAATACGTCTCCTACTAT
TAAATGGTGAAAAATATTTAACGCTGAGAGCTGGAGACTACAGGTTCAACCTTCACATAGCCTCAGGTAAAGTCCTCAAC
AGGATTCTTCCTCACCCAAAATACAGGGTATACATTAAAGACGAGTATATCGAATTCGTTGCCGGAGGAGGGAATTTATT
CAATAAGCATGTCTTAATGGCCGACCCCGGTATCAAGCCAAATGATGAGGTACTGGTTACATCGAGCAATGGAGAACTCA
TAGCTGTTGGCCGGGCTATCATACCTGGCTTTGAAATGGTTTACTATAAAAGAGGGGAAGCTGTTAGAGTTAGGGAGGGT
GTTAAAAAATGA

Upstream 100 bases:

>100_bases
GCATCGCTGAAACTGGAGTCGATGAGTGTGAGAATAGACTCGATGACGCGTGAGCAGGAGGAGTATGTTAAATCATGGAG
GCATGGAACTTGACCACCTG

Downstream 100 bases:

>100_bases
GTTCATTGATATCCCTTGTTAAGACGTCAGAACTCGATCTACGTGAGCTAAGCCCGTCATACTTTATAACTGGCTATCAA
GGATTCGGTATGCTAGGATA

Product: Prefoldin, molecular chaperone implicated in de novo protein folding subunit alpha

Products: NA

Alternate protein names: Archaeal tRNA-guanine transglycosylase [H]

Number of amino acids: Translated: 163; Mature: 163

Protein sequence:

>163_residues
MYSMGFIKRKPSDRELDELRWIAKIQFGVGRDFIPDDIDVVLSRSTLKIRLLLLNGEKYLTLRAGDYRFNLHIASGKVLN
RILPHPKYRVYIKDEYIEFVAGGGNLFNKHVLMADPGIKPNDEVLVTSSNGELIAVGRAIIPGFEMVYYKRGEAVRVREG
VKK

Sequences:

>Translated_163_residues
MYSMGFIKRKPSDRELDELRWIAKIQFGVGRDFIPDDIDVVLSRSTLKIRLLLLNGEKYLTLRAGDYRFNLHIASGKVLN
RILPHPKYRVYIKDEYIEFVAGGGNLFNKHVLMADPGIKPNDEVLVTSSNGELIAVGRAIIPGFEMVYYKRGEAVRVREG
VKK
>Mature_163_residues
MYSMGFIKRKPSDRELDELRWIAKIQFGVGRDFIPDDIDVVLSRSTLKIRLLLLNGEKYLTLRAGDYRFNLHIASGKVLN
RILPHPKYRVYIKDEYIEFVAGGGNLFNKHVLMADPGIKPNDEVLVTSSNGELIAVGRAIIPGFEMVYYKRGEAVRVREG
VKK

Specific function: Exchanges the guanine residue with 7-cyano-7- deazaguanine (preQ0) at position 15 in the dihydrouridine loop (D- loop) of archaeal tRNAs [H]

COG id: COG1370

COG function: function code O; Prefoldin, molecular chaperone implicated in de novo protein folding, alpha subunit

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PUA domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004804
- InterPro:   IPR002478
- InterPro:   IPR015947
- InterPro:   IPR002616
- InterPro:   IPR004521 [H]

Pfam domain/function: PF01472 PUA; PF01702 TGT [H]

EC number: NA

Molecular weight: Translated: 18611; Mature: 18611

Theoretical pI: Translated: 10.08; Mature: 10.08

Prosite motif: PS50890 PUA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MYSMGFIKRKPSDRELDELRWIAKIQFGVGRDFIPDDIDVVLSRSTLKIRLLLLNGEKYL
CCCCCCEECCCCCCCHHHHHEEEEEEECCCCCCCCCCCEEEEECCEEEEEEEEECCCEEE
TLRAGDYRFNLHIASGKVLNRILPHPKYRVYIKDEYIEFVAGGGNLFNKHVLMADPGIKP
EEEECCEEEEEEEECCHHHHHHCCCCCEEEEEEECEEEEEECCCCCCCCEEEEECCCCCC
NDEVLVTSSNGELIAVGRAIIPGFEMVYYKRGEAVRVREGVKK
CCCEEEECCCCCEEEECCCCCCCEEEEEEECCCEEEECCCCCC
>Mature Secondary Structure
MYSMGFIKRKPSDRELDELRWIAKIQFGVGRDFIPDDIDVVLSRSTLKIRLLLLNGEKYL
CCCCCCEECCCCCCCHHHHHEEEEEEECCCCCCCCCCCEEEEECCEEEEEEEEECCCEEE
TLRAGDYRFNLHIASGKVLNRILPHPKYRVYIKDEYIEFVAGGGNLFNKHVLMADPGIKP
EEEECCEEEEEEEECCHHHHHHCCCCCEEEEEEECEEEEEECCCCCCCCEEEEECCCCCC
NDEVLVTSSNGELIAVGRAIIPGFEMVYYKRGEAVRVREGVKK
CCCEEEECCCCCEEEECCCCCCCEEEEEEECCCEEEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9679194 [H]