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The map label for this gene is hyfC [H]

Identifier: 218884331

GI number: 218884331

Start: 969822

End: 970697

Strand: Direct

Name: hyfC [H]

Synonym: DKAM_1020

Alternate gene names: 218884331

Gene position: 969822-970697 (Clockwise)

Preceding gene: 218884330

Following gene: 218884332

Centisome position: 71.04

GC content: 44.86

Gene sequence:

>876_bases
GTGGAGCAATTACTTGCCTTAACAGCTGTAGCTCTCGCAATCCTATTACCAGTATTATATGATGGCATCGAGCGGAAAAC
AAAGGCCATACTACAGAGTAGGGTGGGTCCACCACTTCATCAATCACTGCTGGACCTAGGTAAACTATTATCTAAGGAGC
CTGTGGAGTTCCCATCGTATCCACTAGTATTCTACACCACAGTACTCTCAATAATCCTAGAGTTCGCAGTGATACTAGTA
TTAAATATAGCAGTACTAGGGATAAACACCTCATTGTTAATGCCGGTGGCCATAGCATTAGTAACTGTGGCACAGACCGC
AAACATATCCATGCCGCTCCTAGTCTCGAATCCTTACTCACAGATCGGAGGTATGAGGGAAGTCATGTTAGCGCTTGTGA
ACGAGTTCTCCCTAGTGGCTGGGCTCGCCTTGTTCTACTACTACACAGTCTCCCAACACCCATCCAGCATTATGGGCTGG
GTGATCACTATGCCACTCATAATATTGGTTACCACAGCAACCTATGTTCTATCTGGTAGGGTACCATTCGACATCGCTGA
GGCCGAGGTAGAGCTCGCATCCGGTGTACTTATAGAGTTAAGTGGTAGAGTCCTCGCTTTATACCTGTACTCAATATACT
TGAAGCGATATGTTTCATCCATGCTTGCAGCGGTAGTAGTGTTTACGTTGATGCCGTTGAACCCCTTGACAAGATTCATC
CTGGTGAACGTATCTATCCCCTTCATATGGATACTGTACTCTATAACCAGTGTGATGCTTGGGAGGAGCCGTATAGATCT
CGCTCCAGGCACCTTATTTAAGGTATATATAGTCCTGTTAACGATATCTATAACAGGGTTATTGGTGATTAAATAA

Upstream 100 bases:

>100_bases
CCAGTTCACCATGATAGAGTCTATGTTACTAGCATCACTATGGTTCGGCTTTATAGCAATACTCCTAGTTATTGTGACTA
TATTACTTGGGTGATGAGCC

Downstream 100 bases:

>100_bases
TGCATTCCCAGACGCTTCTAGATAGATACATCCAGCTAGCTGGGAAACTAGGCGGCAAGCATCTCGTGGAAGGAGACATG
GTACACTTATACATACCCCG

Product: hydrogenase-4 component C

Products: H2; oxidized ferredoxin [C]

Alternate protein names: NA

Number of amino acids: Translated: 291; Mature: 291

Protein sequence:

>291_residues
MEQLLALTAVALAILLPVLYDGIERKTKAILQSRVGPPLHQSLLDLGKLLSKEPVEFPSYPLVFYTTVLSIILEFAVILV
LNIAVLGINTSLLMPVAIALVTVAQTANISMPLLVSNPYSQIGGMREVMLALVNEFSLVAGLALFYYYTVSQHPSSIMGW
VITMPLIILVTTATYVLSGRVPFDIAEAEVELASGVLIELSGRVLALYLYSIYLKRYVSSMLAAVVVFTLMPLNPLTRFI
LVNVSIPFIWILYSITSVMLGRSRIDLAPGTLFKVYIVLLTISITGLLVIK

Sequences:

>Translated_291_residues
MEQLLALTAVALAILLPVLYDGIERKTKAILQSRVGPPLHQSLLDLGKLLSKEPVEFPSYPLVFYTTVLSIILEFAVILV
LNIAVLGINTSLLMPVAIALVTVAQTANISMPLLVSNPYSQIGGMREVMLALVNEFSLVAGLALFYYYTVSQHPSSIMGW
VITMPLIILVTTATYVLSGRVPFDIAEAEVELASGVLIELSGRVLALYLYSIYLKRYVSSMLAAVVVFTLMPLNPLTRFI
LVNVSIPFIWILYSITSVMLGRSRIDLAPGTLFKVYIVLLTISITGLLVIK
>Mature_291_residues
MEQLLALTAVALAILLPVLYDGIERKTKAILQSRVGPPLHQSLLDLGKLLSKEPVEFPSYPLVFYTTVLSIILEFAVILV
LNIAVLGINTSLLMPVAIALVTVAQTANISMPLLVSNPYSQIGGMREVMLALVNEFSLVAGLALFYYYTVSQHPSSIMGW
VITMPLIILVTTATYVLSGRVPFDIAEAEVELASGVLIELSGRVLALYLYSIYLKRYVSSMLAAVVVFTLMPLNPLTRFI
LVNVSIPFIWILYSITSVMLGRSRIDLAPGTLFKVYIVLLTISITGLLVIK

Specific function: Unknown

COG id: COG0650

COG function: function code C; Formate hydrogenlyase subunit 4

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the complex I subunit 1 family [H]

Homologues:

Organism=Escherichia coli, GI87082115, Length=242, Percent_Identity=28.9256198347107, Blast_Score=72, Evalue=5e-14,
Organism=Escherichia coli, GI1789077, Length=233, Percent_Identity=32.618025751073, Blast_Score=70, Evalue=2e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001694
- InterPro:   IPR018086 [H]

Pfam domain/function: PF00146 NADHdh [H]

EC number: 1.-.-.- [C]

Molecular weight: Translated: 31847; Mature: 31847

Theoretical pI: Translated: 8.63; Mature: 8.63

Prosite motif: PS00668 COMPLEX1_ND1_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEQLLALTAVALAILLPVLYDGIERKTKAILQSRVGPPLHQSLLDLGKLLSKEPVEFPSY
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCCCCCCC
PLVFYTTVLSIILEFAVILVLNIAVLGINTSLLMPVAIALVTVAQTANISMPLLVSNPYS
CHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCCCEEEECCCHH
QIGGMREVMLALVNEFSLVAGLALFYYYTVSQHPSSIMGWVITMPLIILVTTATYVLSGR
HHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHCCC
VPFDIAEAEVELASGVLIELSGRVLALYLYSIYLKRYVSSMLAAVVVFTLMPLNPLTRFI
CCCHHHHHHHHHHCCEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHH
LVNVSIPFIWILYSITSVMLGRSRIDLAPGTLFKVYIVLLTISITGLLVIK
HHCCHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHEEEEC
>Mature Secondary Structure
MEQLLALTAVALAILLPVLYDGIERKTKAILQSRVGPPLHQSLLDLGKLLSKEPVEFPSY
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCCCCCCC
PLVFYTTVLSIILEFAVILVLNIAVLGINTSLLMPVAIALVTVAQTANISMPLLVSNPYS
CHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCCCEEEECCCHH
QIGGMREVMLALVNEFSLVAGLALFYYYTVSQHPSSIMGWVITMPLIILVTTATYVLSGR
HHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHCCC
VPFDIAEAEVELASGVLIELSGRVLALYLYSIYLKRYVSSMLAAVVVFTLMPLNPLTRFI
CCCHHHHHHHHHHCCEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHH
LVNVSIPFIWILYSITSVMLGRSRIDLAPGTLFKVYIVLLTISITGLLVIK
HHCCHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Proton; reduced ferredoxin [C]

Specific reaction: Proton + reduced ferredoxin = H2 + oxidized ferredoxin [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 9205837; 9278503 [H]