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The map label for this gene is xdhA [H]

Identifier: 218884048

GI number: 218884048

Start: 705371

End: 707713

Strand: Reverse

Name: xdhA [H]

Synonym: DKAM_0737

Alternate gene names: 218884048

Gene position: 707713-705371 (Counterclockwise)

Preceding gene: 218884049

Following gene: 218884047

Centisome position: 51.84

GC content: 48.23

Gene sequence:

>2343_bases
GTGTACTCCTTCATTGGTAAGAGGAGTATTAGAAAGGATGCATTACCTAAGACCAGTGGTACCATTAAATTCGTCAACGA
CTTAGAGGCCCCGGGGATGCTTATTGGTAGGATACTTAGAAGCCCCTATGCCTTCGCCGATATAAGGAGGATAGATGCAA
GCGAGGCAGAGAGACTTGGCGTTGTGGTTTTAACGCCTGATGATATCCCGCAGAAGCCATTTAATCCACGATTAGTAAGC
ATCCATGAGGTGACCTATAAGGATACATACGTCTTAACCAAGAAGCCGAGGTACGTAGGTGACGCTATCGCGGCTGTAGC
TGCTCCAAGCGAGGAGCTTGCACAGAGGGCTATTGAATCGATTAGGATCGAATACGAGAGGATATATGAGCCGATACTGG
ATCCCTTTAAAGCAATGGAACCCGGTGCCCCGTTGATACATGAAAGGATTATGAAGGGCAGTGAATGGGTTAATGTGGAG
AGAAATATAGCTACTACGTTAAATTATGTCGAGGGGGATGTGGATAAGGCTTTCAGGGAATCTAATATCGTTATTGAGAG
GAGGTTTAAGACCGGTAAGAGATACCATATGCAGTTAGAGCCTAAATCTGTTTTATGCATACCTGAACCAGGCGGTAAGC
TGACAATATATGCAACGACGCAGACTATACATAACACCAGGATACTGGTAAGCCAGATCTTCGATATACCGTTAAGCAAG
GTGAATGTGGTTAAGGTACCTATAGGCGGATCCTTCGGCTCCAGTATCCAGGTAAACTACTTGGTTCCAATAGCTGTAGC
ATTATGCCTTAAATCAGGTAAACCCGTCAAGATATCTTATACACGTGAGGAGGATATACTAGACCACTCTAACTTCGTAT
TCCACTTCAGGATGAAGATAGGGGCTAGGAGAGACGGGGTGTTAATGGGTGCCGAATTCGAGAACATCCTCGACGTGGGA
GCTCACCAGGTACAGCCATATCCCCTCCTGGGCACGAGCCTTGGATGGTTTGTCTCGATGTATAAGTGGAGGAATATAAG
GTATATTAGTAAAGCAGTGTACACGAATAAGGTGCCGGCCTGTGCTTTAAGAGGGTACGGGGCACCTGAGGTGCAATGGG
CTGTTGAAACAATGATGGATGAGCTGGCTGAAGAATTGAAGATCGATCCGATAGAGCTCAGGCTGAAGAACTACGTTGGA
AGAGGAGAGATATTCTGGGGGCAGGGACCCACAGTTAAATCAGTTATTAAATCAGATGGAGTCCCCGAGTTACTTGAAAA
AGGAAGAAAGTTAATAGGCTGGGAGAAGAGGAGTCACCCAAGCAGGAAAAAGGGAAGATATAGGAGAGGCATTGGACTGG
CCAGGGGCTTCCATACATCTGGTGCTGGGGGGCCTATCAGCGGGGAGGTAATAGATTATACCGGCTGCATACTCAAGCTC
AACGAAGATGGGACACTTGACTATATAACAGCACTACAAGACCATGGAGGCGGCACCCTCGACGCACATGTCAAGATCAT
CTCAGAGGTCCTAGGGGTACCCCCGGAGCTAGTAAACCTTGCTACTGCTTCAACGGAGAACACGCCGTACGATGTGTGCA
CTCATGCATCAAGGGGAACTTACGCTGGTGGCGAGGCAGCTAGGAGAGCAGCTGAAATAGTTAGATCCAAGATATTCGAG
TACGCGGCCAGGATCGTGGGTAGAGTCGTCAATCCGGAGGCATTCAAGATAAAGTACGATGAAGAGTTGAAGCAAGCCAT
TGTATACGTTGAAGGCACAGATATAAAGATCCCTCTTAGCGAGATAGCTAGGATAGCTTGGCAAAAGAACTGGGGAACAA
TAGGTGCCTTCGTATCCTATAGGGCTACCTCGGCTCCACCAAGCTTCACAGTCTACTTCGTTGAGGTTGAAGTAGATACC
TGGACAGGTAAGGTGAGGCCTATAAGGGTTATAGCCGGCGCAGACGTTGGTACATTGGTAAACCCAGATATGGTTGAGGG
GCAGCTCCACGGTGGCTTTGCAATGGCATGGGGTATGACATTCACGGAGAACACTGTGTACGAGGAGAACGGTGAGTTAG
CTGGGAGAGGCTTGATAACAGATTACAAGATACCAACCATAACGGATACGCCCACACCAGAGGACTTCATTGTTATAACA
GCTGATACCTATGAGCCCACGGGGCCCTTCGGCGCTAAGGGGCTTGGTGAGGCGGCTATGAACCCGGCTGTTGGCGCCAT
AGCCAACGCTATCTACAACGCTATTGGTGTGAGATTCTACGAGCTCCCCATAACGCCTGATAAAATAGTGAAGGCGTTGA
GGGAGAGAGGTGAGATTCCATGA

Upstream 100 bases:

>100_bases
GGATGACGTAGCCAGATACCTGGGGAACCTATGCAGGTGCACCGGCTACATTAAGATAGCTAAAGCCGTGTGGAACGTGG
CAAGTGGGGTGAGGAAGTAA

Downstream 100 bases:

>100_bases
GTATTAAGCCATCGTTGATAAATTATAGGAACACGCATATAATACCGTTTAGATTCGAGTACTATGAACCGGGATCTCTT
AAAGAAGTATTCGAGATACT

Product: Aerobic-type carbon monoxide dehydrogenase, large subunit CoxL/CutL-like protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 780; Mature: 780

Protein sequence:

>780_residues
MYSFIGKRSIRKDALPKTSGTIKFVNDLEAPGMLIGRILRSPYAFADIRRIDASEAERLGVVVLTPDDIPQKPFNPRLVS
IHEVTYKDTYVLTKKPRYVGDAIAAVAAPSEELAQRAIESIRIEYERIYEPILDPFKAMEPGAPLIHERIMKGSEWVNVE
RNIATTLNYVEGDVDKAFRESNIVIERRFKTGKRYHMQLEPKSVLCIPEPGGKLTIYATTQTIHNTRILVSQIFDIPLSK
VNVVKVPIGGSFGSSIQVNYLVPIAVALCLKSGKPVKISYTREEDILDHSNFVFHFRMKIGARRDGVLMGAEFENILDVG
AHQVQPYPLLGTSLGWFVSMYKWRNIRYISKAVYTNKVPACALRGYGAPEVQWAVETMMDELAEELKIDPIELRLKNYVG
RGEIFWGQGPTVKSVIKSDGVPELLEKGRKLIGWEKRSHPSRKKGRYRRGIGLARGFHTSGAGGPISGEVIDYTGCILKL
NEDGTLDYITALQDHGGGTLDAHVKIISEVLGVPPELVNLATASTENTPYDVCTHASRGTYAGGEAARRAAEIVRSKIFE
YAARIVGRVVNPEAFKIKYDEELKQAIVYVEGTDIKIPLSEIARIAWQKNWGTIGAFVSYRATSAPPSFTVYFVEVEVDT
WTGKVRPIRVIAGADVGTLVNPDMVEGQLHGGFAMAWGMTFTENTVYEENGELAGRGLITDYKIPTITDTPTPEDFIVIT
ADTYEPTGPFGAKGLGEAAMNPAVGAIANAIYNAIGVRFYELPITPDKIVKALRERGEIP

Sequences:

>Translated_780_residues
MYSFIGKRSIRKDALPKTSGTIKFVNDLEAPGMLIGRILRSPYAFADIRRIDASEAERLGVVVLTPDDIPQKPFNPRLVS
IHEVTYKDTYVLTKKPRYVGDAIAAVAAPSEELAQRAIESIRIEYERIYEPILDPFKAMEPGAPLIHERIMKGSEWVNVE
RNIATTLNYVEGDVDKAFRESNIVIERRFKTGKRYHMQLEPKSVLCIPEPGGKLTIYATTQTIHNTRILVSQIFDIPLSK
VNVVKVPIGGSFGSSIQVNYLVPIAVALCLKSGKPVKISYTREEDILDHSNFVFHFRMKIGARRDGVLMGAEFENILDVG
AHQVQPYPLLGTSLGWFVSMYKWRNIRYISKAVYTNKVPACALRGYGAPEVQWAVETMMDELAEELKIDPIELRLKNYVG
RGEIFWGQGPTVKSVIKSDGVPELLEKGRKLIGWEKRSHPSRKKGRYRRGIGLARGFHTSGAGGPISGEVIDYTGCILKL
NEDGTLDYITALQDHGGGTLDAHVKIISEVLGVPPELVNLATASTENTPYDVCTHASRGTYAGGEAARRAAEIVRSKIFE
YAARIVGRVVNPEAFKIKYDEELKQAIVYVEGTDIKIPLSEIARIAWQKNWGTIGAFVSYRATSAPPSFTVYFVEVEVDT
WTGKVRPIRVIAGADVGTLVNPDMVEGQLHGGFAMAWGMTFTENTVYEENGELAGRGLITDYKIPTITDTPTPEDFIVIT
ADTYEPTGPFGAKGLGEAAMNPAVGAIANAIYNAIGVRFYELPITPDKIVKALRERGEIP
>Mature_780_residues
MYSFIGKRSIRKDALPKTSGTIKFVNDLEAPGMLIGRILRSPYAFADIRRIDASEAERLGVVVLTPDDIPQKPFNPRLVS
IHEVTYKDTYVLTKKPRYVGDAIAAVAAPSEELAQRAIESIRIEYERIYEPILDPFKAMEPGAPLIHERIMKGSEWVNVE
RNIATTLNYVEGDVDKAFRESNIVIERRFKTGKRYHMQLEPKSVLCIPEPGGKLTIYATTQTIHNTRILVSQIFDIPLSK
VNVVKVPIGGSFGSSIQVNYLVPIAVALCLKSGKPVKISYTREEDILDHSNFVFHFRMKIGARRDGVLMGAEFENILDVG
AHQVQPYPLLGTSLGWFVSMYKWRNIRYISKAVYTNKVPACALRGYGAPEVQWAVETMMDELAEELKIDPIELRLKNYVG
RGEIFWGQGPTVKSVIKSDGVPELLEKGRKLIGWEKRSHPSRKKGRYRRGIGLARGFHTSGAGGPISGEVIDYTGCILKL
NEDGTLDYITALQDHGGGTLDAHVKIISEVLGVPPELVNLATASTENTPYDVCTHASRGTYAGGEAARRAAEIVRSKIFE
YAARIVGRVVNPEAFKIKYDEELKQAIVYVEGTDIKIPLSEIARIAWQKNWGTIGAFVSYRATSAPPSFTVYFVEVEVDT
WTGKVRPIRVIAGADVGTLVNPDMVEGQLHGGFAMAWGMTFTENTVYEENGELAGRGLITDYKIPTITDTPTPEDFIVIT
ADTYEPTGPFGAKGLGEAAMNPAVGAIANAIYNAIGVRFYELPITPDKIVKALRERGEIP

Specific function: Presumed to be a dehydrogenase, but possibly an oxidase. Participates in limited purine salvage (requires aspartate) but does not support aerobic growth on purines as the sole carbon source (purine catabolism) [H]

COG id: COG1529

COG function: function code C; Aerobic-type carbon monoxide dehydrogenase, large subunit CoxL/CutL homologs

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the xanthine dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI91823271, Length=765, Percent_Identity=24.3137254901961, Blast_Score=171, Evalue=2e-42,
Organism=Homo sapiens, GI71773480, Length=757, Percent_Identity=24.4385733157199, Blast_Score=155, Evalue=1e-37,
Organism=Escherichia coli, GI1789230, Length=786, Percent_Identity=31.2977099236641, Blast_Score=329, Evalue=5e-91,
Organism=Escherichia coli, GI1789246, Length=812, Percent_Identity=31.4039408866995, Blast_Score=322, Evalue=6e-89,
Organism=Escherichia coli, GI1786478, Length=795, Percent_Identity=24.4025157232704, Blast_Score=141, Evalue=1e-34,
Organism=Caenorhabditis elegans, GI17539860, Length=768, Percent_Identity=24.7395833333333, Blast_Score=142, Evalue=5e-34,
Organism=Caenorhabditis elegans, GI17540638, Length=790, Percent_Identity=22.1518987341772, Blast_Score=141, Evalue=1e-33,
Organism=Caenorhabditis elegans, GI32566215, Length=595, Percent_Identity=24.0336134453782, Blast_Score=134, Evalue=2e-31,
Organism=Drosophila melanogaster, GI17737937, Length=782, Percent_Identity=22.8900255754476, Blast_Score=150, Evalue=3e-36,
Organism=Drosophila melanogaster, GI24647193, Length=763, Percent_Identity=22.1494102228047, Blast_Score=104, Evalue=2e-22,
Organism=Drosophila melanogaster, GI24647199, Length=752, Percent_Identity=23.0053191489362, Blast_Score=100, Evalue=5e-21,
Organism=Drosophila melanogaster, GI24647201, Length=756, Percent_Identity=21.5608465608466, Blast_Score=82, Evalue=2e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000674
- InterPro:   IPR008274 [H]

Pfam domain/function: PF01315 Ald_Xan_dh_C; PF02738 Ald_Xan_dh_C2 [H]

EC number: =1.17.1.4 [H]

Molecular weight: Translated: 86328; Mature: 86328

Theoretical pI: Translated: 7.92; Mature: 7.92

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MYSFIGKRSIRKDALPKTSGTIKFVNDLEAPGMLIGRILRSPYAFADIRRIDASEAERLG
CCCCCCCCHHHHHCCCCCCCCEEEECCCCCCHHHHHHHHHCCCHHHHHHHCCCCHHHHCE
VVVLTPDDIPQKPFNPRLVSIHEVTYKDTYVLTKKPRYVGDAIAAVAAPSEELAQRAIES
EEEECCCCCCCCCCCCCEEEEEEEEECCEEEEECCCCHHHHHHHHHCCCHHHHHHHHHHH
IRIEYERIYEPILDPFKAMEPGAPLIHERIMKGSEWVNVERNIATTLNYVEGDVDKAFRE
HHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHCCCCEEEECCHHHHHHHHHCCCHHHHHHH
SNIVIERRFKTGKRYHMQLEPKSVLCIPEPGGKLTIYATTQTIHNTRILVSQIFDIPLSK
CCCEEEEECCCCCEEEEEECCCEEEEEECCCCEEEEEEEEEECCCHHHHHHHHHCCCCCC
VNVVKVPIGGSFGSSIQVNYLVPIAVALCLKSGKPVKISYTREEDILDHSNFVFHFRMKI
EEEEEEECCCCCCCCEEEEEHHHHHHHHHHCCCCCEEEEECCCHHCCCCCCEEEEEEEEE
GARRDGVLMGAEFENILDVGAHQVQPYPLLGTSLGWFVSMYKWRNIRYISKAVYTNKVPA
CCCCCCEEECCCHHHHHHCCHHHCCCCCEECCCHHHHHHHHHHCCHHHHHHHHHCCCCCH
CALRGYGAPEVQWAVETMMDELAEELKIDPIELRLKNYVGRGEIFWGQGPTVKSVIKSDG
HHHCCCCCCHHHHHHHHHHHHHHHHHCCCHHEEHHHHCCCCCEEEECCCCHHHHHHHCCC
VPELLEKGRKLIGWEKRSHPSRKKGRYRRGIGLARGFHTSGAGGPISGEVIDYTGCILKL
CHHHHHCCCCEECCCCCCCCCHHHCCHHHCCCHHCCCCCCCCCCCCCCCEEEEEEEEEEE
NEDGTLDYITALQDHGGGTLDAHVKIISEVLGVPPELVNLATASTENTPYDVCTHASRGT
CCCCCEEEEEHHHHCCCCCHHHHHHHHHHHHCCCHHHHHHEECCCCCCCHHHHCCCCCCC
YAGGEAARRAAEIVRSKIFEYAARIVGRVVNPEAFKIKYDEELKQAIVYVEGTDIKIPLS
CCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEHHHHCEEEEEEECCCEEECHH
EIARIAWQKNWGTIGAFVSYRATSAPPSFTVYFVEVEVDTWTGKVRPIRVIAGADVGTLV
HHHHHHHHCCCCCEEHEEEEECCCCCCCEEEEEEEEEEECCCCCCEEEEEEECCCCCCCC
NPDMVEGQLHGGFAMAWGMTFTENTVYEENGELAGRGLITDYKIPTITDTPTPEDFIVIT
CCCCCCCCCCCCEEEEECCEECCCEEEECCCCCCCCCEEECCCCCCCCCCCCCCCEEEEE
ADTYEPTGPFGAKGLGEAAMNPAVGAIANAIYNAIGVRFYELPITPDKIVKALRERGEIP
ECCCCCCCCCCCCCCCHHHCCCHHHHHHHHHHHHHCCEEEEECCCHHHHHHHHHHCCCCC
>Mature Secondary Structure
MYSFIGKRSIRKDALPKTSGTIKFVNDLEAPGMLIGRILRSPYAFADIRRIDASEAERLG
CCCCCCCCHHHHHCCCCCCCCEEEECCCCCCHHHHHHHHHCCCHHHHHHHCCCCHHHHCE
VVVLTPDDIPQKPFNPRLVSIHEVTYKDTYVLTKKPRYVGDAIAAVAAPSEELAQRAIES
EEEECCCCCCCCCCCCCEEEEEEEEECCEEEEECCCCHHHHHHHHHCCCHHHHHHHHHHH
IRIEYERIYEPILDPFKAMEPGAPLIHERIMKGSEWVNVERNIATTLNYVEGDVDKAFRE
HHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHCCCCEEEECCHHHHHHHHHCCCHHHHHHH
SNIVIERRFKTGKRYHMQLEPKSVLCIPEPGGKLTIYATTQTIHNTRILVSQIFDIPLSK
CCCEEEEECCCCCEEEEEECCCEEEEEECCCCEEEEEEEEEECCCHHHHHHHHHCCCCCC
VNVVKVPIGGSFGSSIQVNYLVPIAVALCLKSGKPVKISYTREEDILDHSNFVFHFRMKI
EEEEEEECCCCCCCCEEEEEHHHHHHHHHHCCCCCEEEEECCCHHCCCCCCEEEEEEEEE
GARRDGVLMGAEFENILDVGAHQVQPYPLLGTSLGWFVSMYKWRNIRYISKAVYTNKVPA
CCCCCCEEECCCHHHHHHCCHHHCCCCCEECCCHHHHHHHHHHCCHHHHHHHHHCCCCCH
CALRGYGAPEVQWAVETMMDELAEELKIDPIELRLKNYVGRGEIFWGQGPTVKSVIKSDG
HHHCCCCCCHHHHHHHHHHHHHHHHHCCCHHEEHHHHCCCCCEEEECCCCHHHHHHHCCC
VPELLEKGRKLIGWEKRSHPSRKKGRYRRGIGLARGFHTSGAGGPISGEVIDYTGCILKL
CHHHHHCCCCEECCCCCCCCCHHHCCHHHCCCHHCCCCCCCCCCCCCCCEEEEEEEEEEE
NEDGTLDYITALQDHGGGTLDAHVKIISEVLGVPPELVNLATASTENTPYDVCTHASRGT
CCCCCEEEEEHHHHCCCCCHHHHHHHHHHHHCCCHHHHHHEECCCCCCCHHHHCCCCCCC
YAGGEAARRAAEIVRSKIFEYAARIVGRVVNPEAFKIKYDEELKQAIVYVEGTDIKIPLS
CCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEHHHHCEEEEEEECCCEEECHH
EIARIAWQKNWGTIGAFVSYRATSAPPSFTVYFVEVEVDTWTGKVRPIRVIAGADVGTLV
HHHHHHHHCCCCCEEHEEEEECCCCCCCEEEEEEEEEEECCCCCCEEEEEEECCCCCCCC
NPDMVEGQLHGGFAMAWGMTFTENTVYEENGELAGRGLITDYKIPTITDTPTPEDFIVIT
CCCCCCCCCCCCEEEEECCEECCCEEEECCCCCCCCCEEECCCCCCCCCCCCCCCEEEEE
ADTYEPTGPFGAKGLGEAAMNPAVGAIANAIYNAIGVRFYELPITPDKIVKALRERGEIP
ECCCCCCCCCCCCCCCHHHCCCHHHHHHHHHHHHHCCEEEEECCCHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]