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The map label for this gene is xdhB [H]

Identifier: 218884047

GI number: 218884047

Start: 704469

End: 705374

Strand: Reverse

Name: xdhB [H]

Synonym: DKAM_0736

Alternate gene names: 218884047

Gene position: 705374-704469 (Counterclockwise)

Preceding gene: 218884048

Following gene: 218884046

Centisome position: 51.67

GC content: 47.13

Gene sequence:

>906_bases
ATGAGTATTAAGCCATCGTTGATAAATTATAGGAACACGCATATAATACCGTTTAGATTCGAGTACTATGAACCGGGATC
TCTTAAAGAAGTATTCGAGATACTTGAAAAACTAGGTAATGCAGCTAAGATACTTGCGGGTGGCACTGATCTACTGGTTA
AAATGAAGACTAGGCAAGTGGAGCCGAAGGCACTCGTCAACATTAAGAGGATCAAGGAGCTGAAGGGCATAGTTGACGAG
GGAGATAGGATCAGGATTGGCGCGTTAACAACCCTGAGAGAGCTCGAGGAATCATCACTAATAGCAATGCATCTCCCCGC
ATTACATGACGCGGTTAAACAAATGGCCAGTATACAGATAAGGAATATGGCTACTATTGGTGGTAATCTCTGTAATGCCT
CTCCAGCAGCTGATACAGCACCACCACTACTAGTCCACGAGGCCCTCGTGAAGACCGCCAGCATCGAGGGCGAGAGAATA
ATACCAATCACAGAATTCTTCAAAGGGCCGGGGCTTACAGTGTTGAAGCCAACCGAGTTACTAGTGGAGATCATTGTTAA
CAAGGAAAATGGTTCCTCAGCCTTTAGTAAAATGGGGAGGATAGCGATGGATCTAGCTATCGCCAGTGTAGCTATCTACT
TGAAGACCAGGGGAGATGTCGTTGAGGATGTAAGGGTAGCTGCCGGCGCGGTAGCCCCTACACCGATTAGATGCCCGAGA
ACCGAGACCATGTTAAAGGGGCGTATGATAAATGAGGTAAGCGTTGAGCTGGTCAGAGTAATTGAAGAGGAGGTGAAACC
AATAAGCGACGTTAGGGCGACGGCCGAATACCGTAGACACCTAGTGAAAATCCTGGCCTACGATGTCTTCCATAAGGCGG
TTGAGAGGAGTAGGGGTGGTACTTAA

Upstream 100 bases:

>100_bases
TAGCCAACGCTATCTACAACGCTATTGGTGTGAGATTCTACGAGCTCCCCATAACGCCTGATAAAATAGTGAAGGCGTTG
AGGGAGAGAGGTGAGATTCC

Downstream 100 bases:

>100_bases
TGGTGAAAGTCGTATTCGAGGTTAACGGGAGAACCGTTGAGCTAGATATTGAGCCCAATGAGTTGTTGATCAACACGCTT
AGGAACAGGCTTGGATTAAC

Product: aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM/CutM-like protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 301; Mature: 300

Protein sequence:

>301_residues
MSIKPSLINYRNTHIIPFRFEYYEPGSLKEVFEILEKLGNAAKILAGGTDLLVKMKTRQVEPKALVNIKRIKELKGIVDE
GDRIRIGALTTLRELEESSLIAMHLPALHDAVKQMASIQIRNMATIGGNLCNASPAADTAPPLLVHEALVKTASIEGERI
IPITEFFKGPGLTVLKPTELLVEIIVNKENGSSAFSKMGRIAMDLAIASVAIYLKTRGDVVEDVRVAAGAVAPTPIRCPR
TETMLKGRMINEVSVELVRVIEEEVKPISDVRATAEYRRHLVKILAYDVFHKAVERSRGGT

Sequences:

>Translated_301_residues
MSIKPSLINYRNTHIIPFRFEYYEPGSLKEVFEILEKLGNAAKILAGGTDLLVKMKTRQVEPKALVNIKRIKELKGIVDE
GDRIRIGALTTLRELEESSLIAMHLPALHDAVKQMASIQIRNMATIGGNLCNASPAADTAPPLLVHEALVKTASIEGERI
IPITEFFKGPGLTVLKPTELLVEIIVNKENGSSAFSKMGRIAMDLAIASVAIYLKTRGDVVEDVRVAAGAVAPTPIRCPR
TETMLKGRMINEVSVELVRVIEEEVKPISDVRATAEYRRHLVKILAYDVFHKAVERSRGGT
>Mature_300_residues
SIKPSLINYRNTHIIPFRFEYYEPGSLKEVFEILEKLGNAAKILAGGTDLLVKMKTRQVEPKALVNIKRIKELKGIVDEG
DRIRIGALTTLRELEESSLIAMHLPALHDAVKQMASIQIRNMATIGGNLCNASPAADTAPPLLVHEALVKTASIEGERII
PITEFFKGPGLTVLKPTELLVEIIVNKENGSSAFSKMGRIAMDLAIASVAIYLKTRGDVVEDVRVAAGAVAPTPIRCPRT
ETMLKGRMINEVSVELVRVIEEEVKPISDVRATAEYRRHLVKILAYDVFHKAVERSRGGT

Specific function: Presumed to be a dehydrogenase, but possibly an oxidase. Participates in limited purine salvage (requires aspartate) but does not support aerobic growth on purines as the sole carbon source (purine catabolism) [H]

COG id: COG1319

COG function: function code C; Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM/CutM homologs

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 FAD-binding PCMH-type domain [H]

Homologues:

Organism=Homo sapiens, GI71773480, Length=290, Percent_Identity=27.2413793103448, Blast_Score=81, Evalue=1e-15,
Organism=Escherichia coli, GI1789231, Length=289, Percent_Identity=34.2560553633218, Blast_Score=167, Evalue=9e-43,
Organism=Escherichia coli, GI1789245, Length=271, Percent_Identity=22.140221402214, Blast_Score=63, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI17540638, Length=288, Percent_Identity=25.6944444444444, Blast_Score=87, Evalue=8e-18,
Organism=Drosophila melanogaster, GI17737937, Length=300, Percent_Identity=29.3333333333333, Blast_Score=94, Evalue=1e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005107
- InterPro:   IPR016169
- InterPro:   IPR016166
- InterPro:   IPR016167
- InterPro:   IPR002346 [H]

Pfam domain/function: PF03450 CO_deh_flav_C; PF00941 FAD_binding_5 [H]

EC number: =1.17.1.4 [H]

Molecular weight: Translated: 33139; Mature: 33008

Theoretical pI: Translated: 9.51; Mature: 9.51

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSIKPSLINYRNTHIIPFRFEYYEPGSLKEVFEILEKLGNAAKILAGGTDLLVKMKTRQV
CCCCCCHHCCCCCEEEEEEEECCCCCCHHHHHHHHHHHCCHHEEEECCCCEEEEECCCCC
EPKALVNIKRIKELKGIVDEGDRIRIGALTTLRELEESSLIAMHLPALHDAVKQMASIQI
CHHHHHHHHHHHHHHHHHCCCCEEEEEHHHHHHHHHHCCEEEEECHHHHHHHHHHHHHHH
RNMATIGGNLCNASPAADTAPPLLVHEALVKTASIEGERIIPITEFFKGPGLTVLKPTEL
HHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCEECCHHHHHCCCCCEEECHHHH
LVEIIVNKENGSSAFSKMGRIAMDLAIASVAIYLKTRGDVVEDVRVAAGAVAPTPIRCPR
HHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHEEECCCCHHHHHHHHHCCCCCCCCCCCC
TETMLKGRMINEVSVELVRVIEEEVKPISDVRATAEYRRHLVKILAYDVFHKAVERSRGG
HHHHHHCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
T
C
>Mature Secondary Structure 
SIKPSLINYRNTHIIPFRFEYYEPGSLKEVFEILEKLGNAAKILAGGTDLLVKMKTRQV
CCCCCHHCCCCCEEEEEEEECCCCCCHHHHHHHHHHHCCHHEEEECCCCEEEEECCCCC
EPKALVNIKRIKELKGIVDEGDRIRIGALTTLRELEESSLIAMHLPALHDAVKQMASIQI
CHHHHHHHHHHHHHHHHHCCCCEEEEEHHHHHHHHHHCCEEEEECHHHHHHHHHHHHHHH
RNMATIGGNLCNASPAADTAPPLLVHEALVKTASIEGERIIPITEFFKGPGLTVLKPTEL
HHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCEECCHHHHHCCCCCEEECHHHH
LVEIIVNKENGSSAFSKMGRIAMDLAIASVAIYLKTRGDVVEDVRVAAGAVAPTPIRCPR
HHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHEEECCCCHHHHHHHHHCCCCCCCCCCCC
TETMLKGRMINEVSVELVRVIEEEVKPISDVRATAEYRRHLVKILAYDVFHKAVERSRGG
HHHHHHCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
T
C

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]