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The map label for this gene is ybeM [H]

Identifier: 218884032

GI number: 218884032

Start: 693972

End: 694790

Strand: Direct

Name: ybeM [H]

Synonym: DKAM_0721

Alternate gene names: 218884032

Gene position: 693972-694790 (Clockwise)

Preceding gene: 218884031

Following gene: 218884037

Centisome position: 50.83

GC content: 46.89

Gene sequence:

>819_bases
ATGTCATCGATCACGATTGGAATAGTGCAGGCAGGATTCAATGATCTCCCAGCGGAGAACGCTGGTAAGGCTATTGATAT
AGTGAGGAAGAATTATAAGGAGGCTGATATAGTAGTTCTCCCCGAGTACAGTATGTTGAACCCGTTGAAGATAGGGGATC
CAAGACTAGTATACAGCTACTCGGAGACACCGCTTACAAGCAGGTACCTGACTGAGATGGCTAAGCTTGCTGGAGAGCTA
GGGGTGTTCATACTGGTACATTTTATAGAGAAAACAGATACTCCACCGCTAACCATGAGCACGAGCATAATAGTGACTGA
TAGAGGCGAGGCGATACCGGTCTACAGCAAGATGCACTTGTTTGACGCATACGGCTTCAGGGAGTCAAGCTTCTTCAAGC
CGGGCAATGTACCGGGTAAGATAATATCGATTAAAGGAGTCAAGATAGGTTTCACGATATGTTACGACCTACGCTTCCCA
GAGCTGTACAGGATCACCGCTTTAATGGGCAGCGAGATAATAATCGTGCAGGCAGGCTGGGTGAAGGGACCGCATAAAGA
GGAGATACTTGATAAACTAGCAAGCATAAGGGCACATGAGAACACTGTCTACATAGTCCTAGCTGATCAAACAGGCGATA
TGTTCGTGGGAAGAAGCGGCGTGTTCAATCCGTGGGGCTACAGGGAGCTGGATCTAGGCTGGAGGGAAGCATACGTTGAA
TACACGATAGATGCATCCCTCATAAGTGAGGTAAGGGAGAAACTACCAGTTCTACAACAATCGAAGAATAAATGGGAGAT
AAGGCTGTTGATGCAATAG

Upstream 100 bases:

>100_bases
TTTACTTCCTGCATCGTGTTTAATCCCTAGCATCTTGGATAATATTTGGCCTCACTGGTTAAATAGGTTTCCATGATGCA
TTATTCAAAAAGGGGATGCT

Downstream 100 bases:

>100_bases
GGGCAGCCAGTTAAAACGGGTCAAGCACCGCTAGGAAGCATTGAGGGACTTCCCAATCTTCGATGCAACGTCAGCACCCA
TGTATTTACCATGAACCTTC

Product: Nitrilase/cyanide hydratase and apolipoprotein N-acyltransferase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 272; Mature: 271

Protein sequence:

>272_residues
MSSITIGIVQAGFNDLPAENAGKAIDIVRKNYKEADIVVLPEYSMLNPLKIGDPRLVYSYSETPLTSRYLTEMAKLAGEL
GVFILVHFIEKTDTPPLTMSTSIIVTDRGEAIPVYSKMHLFDAYGFRESSFFKPGNVPGKIISIKGVKIGFTICYDLRFP
ELYRITALMGSEIIIVQAGWVKGPHKEEILDKLASIRAHENTVYIVLADQTGDMFVGRSGVFNPWGYRELDLGWREAYVE
YTIDASLISEVREKLPVLQQSKNKWEIRLLMQ

Sequences:

>Translated_272_residues
MSSITIGIVQAGFNDLPAENAGKAIDIVRKNYKEADIVVLPEYSMLNPLKIGDPRLVYSYSETPLTSRYLTEMAKLAGEL
GVFILVHFIEKTDTPPLTMSTSIIVTDRGEAIPVYSKMHLFDAYGFRESSFFKPGNVPGKIISIKGVKIGFTICYDLRFP
ELYRITALMGSEIIIVQAGWVKGPHKEEILDKLASIRAHENTVYIVLADQTGDMFVGRSGVFNPWGYRELDLGWREAYVE
YTIDASLISEVREKLPVLQQSKNKWEIRLLMQ
>Mature_271_residues
SSITIGIVQAGFNDLPAENAGKAIDIVRKNYKEADIVVLPEYSMLNPLKIGDPRLVYSYSETPLTSRYLTEMAKLAGELG
VFILVHFIEKTDTPPLTMSTSIIVTDRGEAIPVYSKMHLFDAYGFRESSFFKPGNVPGKIISIKGVKIGFTICYDLRFPE
LYRITALMGSEIIIVQAGWVKGPHKEEILDKLASIRAHENTVYIVLADQTGDMFVGRSGVFNPWGYRELDLGWREAYVEY
TIDASLISEVREKLPVLQQSKNKWEIRLLMQ

Specific function: Unknown

COG id: COG0388

COG function: function code R; Predicted amidohydrolase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 CN hydrolase domain [H]

Homologues:

Organism=Homo sapiens, GI9910460, Length=276, Percent_Identity=26.8115942028986, Blast_Score=96, Evalue=4e-20,
Organism=Homo sapiens, GI297632350, Length=226, Percent_Identity=30.0884955752212, Blast_Score=82, Evalue=4e-16,
Organism=Homo sapiens, GI297632348, Length=226, Percent_Identity=30.0884955752212, Blast_Score=82, Evalue=4e-16,
Organism=Homo sapiens, GI5031947, Length=226, Percent_Identity=30.0884955752212, Blast_Score=82, Evalue=5e-16,
Organism=Caenorhabditis elegans, GI17556280, Length=268, Percent_Identity=25.7462686567164, Blast_Score=66, Evalue=1e-11,
Organism=Saccharomyces cerevisiae, GI6323383, Length=283, Percent_Identity=29.3286219081272, Blast_Score=75, Evalue=8e-15,
Organism=Drosophila melanogaster, GI21355835, Length=215, Percent_Identity=31.6279069767442, Blast_Score=88, Evalue=7e-18,
Organism=Drosophila melanogaster, GI17933642, Length=281, Percent_Identity=24.5551601423488, Blast_Score=74, Evalue=8e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003010
- InterPro:   IPR001110 [H]

Pfam domain/function: PF00795 CN_hydrolase [H]

EC number: 3.5.-.- [C]

Molecular weight: Translated: 30662; Mature: 30531

Theoretical pI: Translated: 6.15; Mature: 6.15

Prosite motif: PS50263 CN_HYDROLASE ; PS01227 UPF0012

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSSITIGIVQAGFNDLPAENAGKAIDIVRKNYKEADIVVLPEYSMLNPLKIGDPRLVYSY
CCCEEEEEEECCCCCCCCCCCCCCHHHHHHCCCCCCEEEECCCCCCCCEECCCCEEEEEE
SETPLTSRYLTEMAKLAGELGVFILVHFIEKTDTPPLTMSTSIIVTDRGEAIPVYSKMHL
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEEEEECCCCEEEEHHHEEE
FDAYGFRESSFFKPGNVPGKIISIKGVKIGFTICYDLRFPELYRITALMGSEIIIVQAGW
EECCCCCCCCCCCCCCCCCEEEEEECEEEEEEEEEECCCCHHHHHHHHHCCEEEEEEECC
VKGPHKEEILDKLASIRAHENTVYIVLADQTGDMFVGRSGVFNPWGYRELDLGWREAYVE
CCCCCHHHHHHHHHHHEECCCEEEEEEECCCCCEEECCCCCCCCCCCEEECCCHHHEEEE
YTIDASLISEVREKLPVLQQSKNKWEIRLLMQ
EEECHHHHHHHHHHCCHHHCCCCCEEEEEEEC
>Mature Secondary Structure 
SSITIGIVQAGFNDLPAENAGKAIDIVRKNYKEADIVVLPEYSMLNPLKIGDPRLVYSY
CCEEEEEEECCCCCCCCCCCCCCHHHHHHCCCCCCEEEECCCCCCCCEECCCCEEEEEE
SETPLTSRYLTEMAKLAGELGVFILVHFIEKTDTPPLTMSTSIIVTDRGEAIPVYSKMHL
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEEEEECCCCEEEEHHHEEE
FDAYGFRESSFFKPGNVPGKIISIKGVKIGFTICYDLRFPELYRITALMGSEIIIVQAGW
EECCCCCCCCCCCCCCCCCEEEEEECEEEEEEEEEECCCCHHHHHHHHHCCEEEEEEECC
VKGPHKEEILDKLASIRAHENTVYIVLADQTGDMFVGRSGVFNPWGYRELDLGWREAYVE
CCCCCHHHHHHHHHHHEECCCEEEEEEECCCCCEEECCCCCCCCCCCEEECCCHHHEEEE
YTIDASLISEVREKLPVLQQSKNKWEIRLLMQ
EEECHHHHHHHHHHCCHHHCCCCCEEEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]