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The map label for this gene is 218883968

Identifier: 218883968

GI number: 218883968

Start: 631719

End: 632813

Strand: Reverse

Name: 218883968

Synonym: DKAM_0657

Alternate gene names: NA

Gene position: 632813-631719 (Counterclockwise)

Preceding gene: 218883970

Following gene: 218883966

Centisome position: 46.35

GC content: 45.21

Gene sequence:

>1095_bases
ATGGTTTTGACTATAGACTGGGACGAAGTCAGGAAGAAGCGCGAGGAATTCTGGAGCAGTAGTCCTGTTTACAAGGCTAT
TTATGATAGGCTAGTGAAGCAGGGCTATCACTTGATAGGTACTATAGGAGCTGTTAAAAGATGTCACTGGAGCAAGGAAG
CCGTATTGAGGAATAGGTATTGCTATAAGTGTCTATGGTACGGTATTGAGAGCCATAGATGTATACAGATGACGCCTGTA
GTAGCATGGTGCTGGAATAGGTGCCTTCACTGCTGGAGGCTCCAGCCAGAGGATATAGGCATGCACTGGGATGACACGCG
TCCCCCAGTGATCGATGATCCAGAGATCCTGGTCGAAGAAAGTATTAGGGCCCACAGAGAGATCATGGCTGGTTTCAAGG
GCAATCCAAGGGCTGATCAAAAACTGGTTGAAGAAGCATTGAATCCCAAGCATGCAGCCATAAGCCTAACCGGTGAACCA
ATACTTTATCCAAGGCTTGGTGAGCTAATAAGCGAGTATCATAAGAGAGGCATCACTACATTCCTTGTCACACATGGTAC
AAGGCCTGATACTCTCAGGAACCTTGAAACAGAGCCGAGTCAGCTGTATATAAGTATAGAGTCATGGGATAAAGATAGCT
ACGAGCACTTTAACCGCCCCTTAGTACCAAGGGCATGGGAGTTATTTAATGAAACACTTGAATTAATACCCAGCTTCAAG
TCTCCCACGGTATTCAGGTTCACGATAGTAAAGGGGTTCAACGATCATGAAATAGCTCTTAAGAACTTCGCTAAATTCGT
TGAAAAAGCACAACCATCATACGTAGAGGTCAAGGCATACATGTATATCGGGGGAAGCAGAGGTAGGTTATTCAAAAACA
ATATGCCAAGCCATATAGAGGTAAGGGAAATAGCCAGGAAAATAGCTGAGTTAACAGGTTACACAGTGATGAGCGAGTCC
GTACCAAGCCGTATAGTTCTCTTAAGCAGGGTAGGTAAGCCGAAAAGACATGGTAGGGGATGCCCTGATGGGGTGGAGAA
CCCTGAGAAATATGTACCGGTATTAACGGAGGAGTATGAGGAAATACAGGATTAG

Upstream 100 bases:

>100_bases
ACACGGGTTCGCTCATCACTATACTTAACTATTAGTTGGGAGTGGTTAAATACCTTTGATTTATAACTCTGTTAAAACAT
TAGTAGACATGAAAAGGTGA

Downstream 100 bases:

>100_bases
TCCTTCACAATATTATGGATCCTGTATTTCACGCGTTGACCAAGCGGTATTCTTTCCCAGCGTATAATATTACAAGCATT
TCATTCCTCATCTCGTTTAA

Product: tRNA-modifying enzyme

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 364; Mature: 364

Protein sequence:

>364_residues
MVLTIDWDEVRKKREEFWSSSPVYKAIYDRLVKQGYHLIGTIGAVKRCHWSKEAVLRNRYCYKCLWYGIESHRCIQMTPV
VAWCWNRCLHCWRLQPEDIGMHWDDTRPPVIDDPEILVEESIRAHREIMAGFKGNPRADQKLVEEALNPKHAAISLTGEP
ILYPRLGELISEYHKRGITTFLVTHGTRPDTLRNLETEPSQLYISIESWDKDSYEHFNRPLVPRAWELFNETLELIPSFK
SPTVFRFTIVKGFNDHEIALKNFAKFVEKAQPSYVEVKAYMYIGGSRGRLFKNNMPSHIEVREIARKIAELTGYTVMSES
VPSRIVLLSRVGKPKRHGRGCPDGVENPEKYVPVLTEEYEEIQD

Sequences:

>Translated_364_residues
MVLTIDWDEVRKKREEFWSSSPVYKAIYDRLVKQGYHLIGTIGAVKRCHWSKEAVLRNRYCYKCLWYGIESHRCIQMTPV
VAWCWNRCLHCWRLQPEDIGMHWDDTRPPVIDDPEILVEESIRAHREIMAGFKGNPRADQKLVEEALNPKHAAISLTGEP
ILYPRLGELISEYHKRGITTFLVTHGTRPDTLRNLETEPSQLYISIESWDKDSYEHFNRPLVPRAWELFNETLELIPSFK
SPTVFRFTIVKGFNDHEIALKNFAKFVEKAQPSYVEVKAYMYIGGSRGRLFKNNMPSHIEVREIARKIAELTGYTVMSES
VPSRIVLLSRVGKPKRHGRGCPDGVENPEKYVPVLTEEYEEIQD
>Mature_364_residues
MVLTIDWDEVRKKREEFWSSSPVYKAIYDRLVKQGYHLIGTIGAVKRCHWSKEAVLRNRYCYKCLWYGIESHRCIQMTPV
VAWCWNRCLHCWRLQPEDIGMHWDDTRPPVIDDPEILVEESIRAHREIMAGFKGNPRADQKLVEEALNPKHAAISLTGEP
ILYPRLGELISEYHKRGITTFLVTHGTRPDTLRNLETEPSQLYISIESWDKDSYEHFNRPLVPRAWELFNETLELIPSFK
SPTVFRFTIVKGFNDHEIALKNFAKFVEKAQPSYVEVKAYMYIGGSRGRLFKNNMPSHIEVREIARKIAELTGYTVMSES
VPSRIVLLSRVGKPKRHGRGCPDGVENPEKYVPVLTEEYEEIQD

Specific function: Unknown

COG id: COG0731

COG function: function code C; Fe-S oxidoreductases

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the UPF0026 family [H]

Homologues:

Organism=Homo sapiens, GI50726981, Length=307, Percent_Identity=37.1335504885993, Blast_Score=203, Evalue=2e-52,
Organism=Homo sapiens, GI224282123, Length=262, Percent_Identity=34.3511450381679, Blast_Score=159, Evalue=3e-39,
Organism=Homo sapiens, GI224282125, Length=275, Percent_Identity=33.8181818181818, Blast_Score=159, Evalue=5e-39,
Organism=Saccharomyces cerevisiae, GI6325049, Length=291, Percent_Identity=34.3642611683849, Blast_Score=182, Evalue=7e-47,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006638
- InterPro:   IPR007197
- InterPro:   IPR013917 [H]

Pfam domain/function: PF04055 Radical_SAM; PF08608 Wyosine_form [H]

EC number: NA

Molecular weight: Translated: 42435; Mature: 42435

Theoretical pI: Translated: 7.81; Mature: 7.81

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.2 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
2.2 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVLTIDWDEVRKKREEFWSSSPVYKAIYDRLVKQGYHLIGTIGAVKRCHWSKEAVLRNRY
CEEEECHHHHHHHHHHHCCCCCHHHHHHHHHHHCCHHHHHHHHHHHHHCCCHHHHHHHHH
CYKCLWYGIESHRCIQMTPVVAWCWNRCLHCWRLQPEDIGMHWDDTRPPVIDDPEILVEE
HHHHHHHCCCCCCEEEEHHHHHHHHHHHHHHHCCCHHHCCCCCCCCCCCCCCCHHHHHHH
SIRAHREIMAGFKGNPRADQKLVEEALNPKHAAISLTGEPILYPRLGELISEYHKRGITT
HHHHHHHHHHCCCCCCCHHHHHHHHHCCCCCEEEEECCCCEECHHHHHHHHHHHHCCCEE
FLVTHGTRPDTLRNLETEPSQLYISIESWDKDSYEHFNRPLVPRAWELFNETLELIPSFK
EEEECCCCCHHHHCCCCCCCEEEEEEECCCCHHHHHCCCCCCHHHHHHHHHHHHHCCCCC
SPTVFRFTIVKGFNDHEIALKNFAKFVEKAQPSYVEVKAYMYIGGSRGRLFKNNMPSHIE
CCEEEEEEEEECCCCHHHHHHHHHHHHHHCCCCEEEEEEEEEEECCCCCEECCCCCCCCH
VREIARKIAELTGYTVMSESVPSRIVLLSRVGKPKRHGRGCPDGVENPEKYVPVLTEEYE
HHHHHHHHHHHHCCCHHHCCCCHHHHHHHHCCCCHHCCCCCCCCCCCHHHHCCHHHHHHH
EIQD
HHCC
>Mature Secondary Structure
MVLTIDWDEVRKKREEFWSSSPVYKAIYDRLVKQGYHLIGTIGAVKRCHWSKEAVLRNRY
CEEEECHHHHHHHHHHHCCCCCHHHHHHHHHHHCCHHHHHHHHHHHHHCCCHHHHHHHHH
CYKCLWYGIESHRCIQMTPVVAWCWNRCLHCWRLQPEDIGMHWDDTRPPVIDDPEILVEE
HHHHHHHCCCCCCEEEEHHHHHHHHHHHHHHHCCCHHHCCCCCCCCCCCCCCCHHHHHHH
SIRAHREIMAGFKGNPRADQKLVEEALNPKHAAISLTGEPILYPRLGELISEYHKRGITT
HHHHHHHHHHCCCCCCCHHHHHHHHHCCCCCEEEEECCCCEECHHHHHHHHHHHHCCCEE
FLVTHGTRPDTLRNLETEPSQLYISIESWDKDSYEHFNRPLVPRAWELFNETLELIPSFK
EEEECCCCCHHHHCCCCCCCEEEEEEECCCCHHHHHCCCCCCHHHHHHHHHHHHHCCCCC
SPTVFRFTIVKGFNDHEIALKNFAKFVEKAQPSYVEVKAYMYIGGSRGRLFKNNMPSHIE
CCEEEEEEEEECCCCHHHHHHHHHHHHHHCCCCEEEEEEEEEEECCCCCEECCCCCCCCH
VREIARKIAELTGYTVMSESVPSRIVLLSRVGKPKRHGRGCPDGVENPEKYVPVLTEEYE
HHHHHHHHHHHHCCCHHHCCCCHHHHHHHHCCCCHHCCCCCCCCCCCHHHHCCHHHHHHH
EIQD
HHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]