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The map label for this gene is lysS [H]

Identifier: 218883933

GI number: 218883933

Start: 590132

End: 591772

Strand: Reverse

Name: lysS [H]

Synonym: DKAM_0622

Alternate gene names: 218883933

Gene position: 591772-590132 (Counterclockwise)

Preceding gene: 218883938

Following gene: 218883928

Centisome position: 43.35

GC content: 45.4

Gene sequence:

>1641_bases
ATGGTTAGACACTGGATCGACGAGCTGGCCGACAACATCTACAACGCATTGACAAAGAGAGGTAAAGAGGTATATGTATT
CAATGGTGGGCTCTCAGTCTCAGGACTACAGCATGTTGGAAGACTACGCGGTGAAATAATAATAGCTGAGACGTTGAGGA
AAATACTCAGTGAACGAGGACTCAAGATAAAACAATACCTCACACTCTACACGCAAGATGCTTGGAAGGGAAAGGAGCAA
CAATTGAAGCAGTTCCCCAATCCAGGTGAGGCAGCAAGGTACAAGGGTAATCCATTAATTAGAGTACCTGATCCAAAGGG
GTGCCATGGTAACTGGGTTGAACACTATTGGAGTGATTTTGGGCCATTCATCAACGAGTTCACAGACGGCAATATCGAGG
TAATTACAACAACAGACATGTATAAGGACAAGATGAAGCAATTCATAAAGCTAACGCTTGAGAAGCGAGAAGAGGTCAGG
AAAACAATCAACAAGTACAGGGGTAGAAAACCATACTCTGAGGGATGGATACCAATCGAGCCAGTATGCGAGAAATGCGG
GAGAATAGATACAACAGAGGCTGTAAGGCTAATCGATGAAGACCACGTCGAATATGTCTGCGAGCACTGTGGTTACAAAG
GGGTTACAGAGATAAGTAATGGGAAACTAATGTGGAGAATAGAATGGGTTGGCATATGGTGGACGCTTGGAGTAGACTTC
GAACCCTACGGCAAGGATCATGCGATGCCTGGTGGAAGCAGAGATAGCTGTGTAGACCTAGCGGTAAACGTCTATGGGAT
AAAACCACCGGAGGGGCTACCATACGAGTGGGTGGAGTGGAGGACACCCACAGGACAAATAGCAGACATGGGAAGCAGTG
ATTTTCTGGGATTCACGCCAAGGGACTGGGTGGAGGTAGCGCATCCACATATATATAGGTTTATCGTGTTGAAGACGCCG
CCAATGAAGAAATATGCTGTTGGATTACACGAAGTCCCCCAGTATTATAGCCAGTACTACAAGGCTGAGAGAATATATTA
CGGGCTAGAGAAAGCGAAGGATGAAGAGGAGGAAGTCATATTAAAGAGGAGCTATGAGCTAAGCTATCCAAAGGGAGCCC
CACCAAGGGAACCTCCCGAGCAAATACCCTATACACACCTCGCTGTTCTAGCCCAGATAATACCAAGGGATAAATGGGTT
GATGAGGGCTTAAAGAGATTGAAGAACATTGGGTTACTCCCAGCTGAACCAAGTCGCTACGGGGTTCAAAGAGTCCTTGA
AACTATTCCAAGGGCTTATATATGGGCAGTTAAATATGGTGGCGAGGCAAACGTATTCACATTGAATACTATTGAAGAGG
CCGGCAAGAAGGCTCGGGAAATACCAGGAGAGTATATAGGGCTATTCATACGGTTATATGAGGGGCTCTCAACATTAAGC
GAGTGGAGTGAGGAAGCAATTAAGAATATAATGGTTAATATAACGAGCTCACTGGAGAAAAACAAGGTTAACGACTTCTA
TAAATACTTTTACATGCTGTACATTGGAAAACCAAGTGGACCTAGGGCCGCCCCATTACTCGCTCTAATGGGTAGGGAGC
AGGCACTCAGGTACCTCGAAGTATTTAAATACACTAAGTGA

Upstream 100 bases:

>100_bases
CCCAATAACATTTTATAATCGTTACAATACACTAATAGAGCTGAAAATACATTAATAAGCCTTTGACACCACTATCCATT
TATGGCATGGTGCATTTGAG

Downstream 100 bases:

>100_bases
GAACCGGACTTAAACCTGGTTTTCAAAATTTAAGTGAATACTAAGAGGAAGGAAAAGAAGAAAAAGCTTTTTGATAAAAG
CTATATGCTATACTGTCTTT

Product: lysyl-tRNA synthetase

Products: NA

Alternate protein names: Lysine--tRNA ligase; LysRS [H]

Number of amino acids: Translated: 546; Mature: 546

Protein sequence:

>546_residues
MVRHWIDELADNIYNALTKRGKEVYVFNGGLSVSGLQHVGRLRGEIIIAETLRKILSERGLKIKQYLTLYTQDAWKGKEQ
QLKQFPNPGEAARYKGNPLIRVPDPKGCHGNWVEHYWSDFGPFINEFTDGNIEVITTTDMYKDKMKQFIKLTLEKREEVR
KTINKYRGRKPYSEGWIPIEPVCEKCGRIDTTEAVRLIDEDHVEYVCEHCGYKGVTEISNGKLMWRIEWVGIWWTLGVDF
EPYGKDHAMPGGSRDSCVDLAVNVYGIKPPEGLPYEWVEWRTPTGQIADMGSSDFLGFTPRDWVEVAHPHIYRFIVLKTP
PMKKYAVGLHEVPQYYSQYYKAERIYYGLEKAKDEEEEVILKRSYELSYPKGAPPREPPEQIPYTHLAVLAQIIPRDKWV
DEGLKRLKNIGLLPAEPSRYGVQRVLETIPRAYIWAVKYGGEANVFTLNTIEEAGKKAREIPGEYIGLFIRLYEGLSTLS
EWSEEAIKNIMVNITSSLEKNKVNDFYKYFYMLYIGKPSGPRAAPLLALMGREQALRYLEVFKYTK

Sequences:

>Translated_546_residues
MVRHWIDELADNIYNALTKRGKEVYVFNGGLSVSGLQHVGRLRGEIIIAETLRKILSERGLKIKQYLTLYTQDAWKGKEQ
QLKQFPNPGEAARYKGNPLIRVPDPKGCHGNWVEHYWSDFGPFINEFTDGNIEVITTTDMYKDKMKQFIKLTLEKREEVR
KTINKYRGRKPYSEGWIPIEPVCEKCGRIDTTEAVRLIDEDHVEYVCEHCGYKGVTEISNGKLMWRIEWVGIWWTLGVDF
EPYGKDHAMPGGSRDSCVDLAVNVYGIKPPEGLPYEWVEWRTPTGQIADMGSSDFLGFTPRDWVEVAHPHIYRFIVLKTP
PMKKYAVGLHEVPQYYSQYYKAERIYYGLEKAKDEEEEVILKRSYELSYPKGAPPREPPEQIPYTHLAVLAQIIPRDKWV
DEGLKRLKNIGLLPAEPSRYGVQRVLETIPRAYIWAVKYGGEANVFTLNTIEEAGKKAREIPGEYIGLFIRLYEGLSTLS
EWSEEAIKNIMVNITSSLEKNKVNDFYKYFYMLYIGKPSGPRAAPLLALMGREQALRYLEVFKYTK
>Mature_546_residues
MVRHWIDELADNIYNALTKRGKEVYVFNGGLSVSGLQHVGRLRGEIIIAETLRKILSERGLKIKQYLTLYTQDAWKGKEQ
QLKQFPNPGEAARYKGNPLIRVPDPKGCHGNWVEHYWSDFGPFINEFTDGNIEVITTTDMYKDKMKQFIKLTLEKREEVR
KTINKYRGRKPYSEGWIPIEPVCEKCGRIDTTEAVRLIDEDHVEYVCEHCGYKGVTEISNGKLMWRIEWVGIWWTLGVDF
EPYGKDHAMPGGSRDSCVDLAVNVYGIKPPEGLPYEWVEWRTPTGQIADMGSSDFLGFTPRDWVEVAHPHIYRFIVLKTP
PMKKYAVGLHEVPQYYSQYYKAERIYYGLEKAKDEEEEVILKRSYELSYPKGAPPREPPEQIPYTHLAVLAQIIPRDKWV
DEGLKRLKNIGLLPAEPSRYGVQRVLETIPRAYIWAVKYGGEANVFTLNTIEEAGKKAREIPGEYIGLFIRLYEGLSTLS
EWSEEAIKNIMVNITSSLEKNKVNDFYKYFYMLYIGKPSGPRAAPLLALMGREQALRYLEVFKYTK

Specific function: Unknown

COG id: COG1384

COG function: function code J; Lysyl-tRNA synthetase (class I)

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I aminoacyl-tRNA synthetase family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008925
- InterPro:   IPR020751
- InterPro:   IPR002904
- InterPro:   IPR020754
- InterPro:   IPR020756
- InterPro:   IPR014729 [H]

Pfam domain/function: PF01921 tRNA-synt_1f [H]

EC number: =6.1.1.6 [H]

Molecular weight: Translated: 63168; Mature: 63168

Theoretical pI: Translated: 8.08; Mature: 8.08

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVRHWIDELADNIYNALTKRGKEVYVFNGGLSVSGLQHVGRLRGEIIIAETLRKILSERG
CCHHHHHHHHHHHHHHHHHCCCEEEEEECCCCHHHHHHHHHHHCCEEHHHHHHHHHHHCC
LKIKQYLTLYTQDAWKGKEQQLKQFPNPGEAARYKGNPLIRVPDPKGCHGNWVEHYWSDF
CCHHHHHHHHHHHHCCCHHHHHHHCCCCCCCCCCCCCCEEECCCCCCCCCCHHHHHHHHH
GPFINEFTDGNIEVITTTDMYKDKMKQFIKLTLEKREEVRKTINKYRGRKPYSEGWIPIE
HHHHHHCCCCCEEEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHH
PVCEKCGRIDTTEAVRLIDEDHVEYVCEHCGYKGVTEISNGKLMWRIEWVGIWWTLGVDF
HHHHHCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEEEEEEEEEEEEECCCC
EPYGKDHAMPGGSRDSCVDLAVNVYGIKPPEGLPYEWVEWRTPTGQIADMGSSDFLGFTP
CCCCCCCCCCCCCCCCCEEEEEEEEECCCCCCCCCCCEEECCCCCHHHCCCCCCCCCCCC
RDWVEVAHPHIYRFIVLKTPPMKKYAVGLHEVPQYYSQYYKAERIYYGLEKAKDEEEEVI
HHHHHHCCCCEEEEEEEECCCCHHHHCCHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHH
LKRSYELSYPKGAPPREPPEQIPYTHLAVLAQIIPRDKWVDEGLKRLKNIGLLPAEPSRY
HHHCCCCCCCCCCCCCCCHHHCCHHHHHHHHHHHCCHHHHHHHHHHHHHCCCCCCCCHHH
GVQRVLETIPRAYIWAVKYGGEANVFTLNTIEEAGKKAREIPGEYIGLFIRLYEGLSTLS
HHHHHHHHCCHHEEEEEEECCCCCEEEEHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHH
EWSEEAIKNIMVNITSSLEKNKVNDFYKYFYMLYIGKPSGPRAAPLLALMGREQALRYLE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEECCCCCCHHHHHHHHCHHHHHHHHH
VFKYTK
HHHCCC
>Mature Secondary Structure
MVRHWIDELADNIYNALTKRGKEVYVFNGGLSVSGLQHVGRLRGEIIIAETLRKILSERG
CCHHHHHHHHHHHHHHHHHCCCEEEEEECCCCHHHHHHHHHHHCCEEHHHHHHHHHHHCC
LKIKQYLTLYTQDAWKGKEQQLKQFPNPGEAARYKGNPLIRVPDPKGCHGNWVEHYWSDF
CCHHHHHHHHHHHHCCCHHHHHHHCCCCCCCCCCCCCCEEECCCCCCCCCCHHHHHHHHH
GPFINEFTDGNIEVITTTDMYKDKMKQFIKLTLEKREEVRKTINKYRGRKPYSEGWIPIE
HHHHHHCCCCCEEEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHH
PVCEKCGRIDTTEAVRLIDEDHVEYVCEHCGYKGVTEISNGKLMWRIEWVGIWWTLGVDF
HHHHHCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEEEEEEEEEEEEECCCC
EPYGKDHAMPGGSRDSCVDLAVNVYGIKPPEGLPYEWVEWRTPTGQIADMGSSDFLGFTP
CCCCCCCCCCCCCCCCCEEEEEEEEECCCCCCCCCCCEEECCCCCHHHCCCCCCCCCCCC
RDWVEVAHPHIYRFIVLKTPPMKKYAVGLHEVPQYYSQYYKAERIYYGLEKAKDEEEEVI
HHHHHHCCCCEEEEEEEECCCCHHHHCCHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHH
LKRSYELSYPKGAPPREPPEQIPYTHLAVLAQIIPRDKWVDEGLKRLKNIGLLPAEPSRY
HHHCCCCCCCCCCCCCCCHHHCCHHHHHHHHHHHCCHHHHHHHHHHHHHCCCCCCCCHHH
GVQRVLETIPRAYIWAVKYGGEANVFTLNTIEEAGKKAREIPGEYIGLFIRLYEGLSTLS
HHHHHHHHCCHHEEEEEEECCCCCEEEEHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHH
EWSEEAIKNIMVNITSSLEKNKVNDFYKYFYMLYIGKPSGPRAAPLLALMGREQALRYLE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEECCCCCCHHHHHHHHCHHHHHHHHH
VFKYTK
HHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 10382966 [H]