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The map label for this gene is 218883791

Identifier: 218883791

GI number: 218883791

Start: 447549

End: 448691

Strand: Reverse

Name: 218883791

Synonym: DKAM_0480

Alternate gene names: NA

Gene position: 448691-447549 (Counterclockwise)

Preceding gene: 218883792

Following gene: 218883790

Centisome position: 32.87

GC content: 46.54

Gene sequence:

>1143_bases
TTGGGCCAGGATACATGGGTTTTTTCACGGTGTCTGAAATGCGGGTGGAGTGAGAAAGGGTTACATCTTAAATGCCCTGT
ATGTGGAGGTGTAACTGTTCTAGAGTATGAGAGAGCCTCCCTAAGTATAGAGAGGAATGAGGCAAGTATCTGGAGGTATA
GGGGTCTTCTACCAGGGTTTCCCCGTAAGATATCGATGGGCGAGGGGCTTACACCGCTTAGAGTGGTGAATGGAGTACTA
GTTAAAAACGAGAGAAAGAATCCCACGGGCTCATACTCTGATAGAGCGTCAAGCATTATTGCCAGTTACCTAGCTTCTAC
GGGTAGAAAAATCATTAGCGTCGAGTATGCCGAGGACTTCGCTTACTCCGTTACGTATTATACGCGTAGATTGGTTAAGG
GAAGCATAGTAATCAAGGATCCTTTTAACGCTGACGTTGATGAATTAATCAGTATTCACAGGGCTGGCTTCACCATAAAA
ATAGGTGATACAGGGGAAGCGGACATCCCCTACATTAATCCACTAACTATAGAGGGATTGAAGACTATATTGCTCGAGAT
ATATGAGAGGAAACTCAGGGCTGAAAACGTTATTGTACCGGTTGAAACAGGTACCCTAGCCTTCTCGCTCTGCAAAGCCC
TCAAAGAGCTCAGCTATCTAGGCATAGATCCAGGATACGTGATCATGGGGGCTATGGTGAAGGGTGCCGAGAAACCCTGG
CTCATAGAACACTGTAGTAACAGTGTTAAAATAGAAGAGGTCGATAAGGCTGAGGCATTGGAAGCACTACTTGAATTAAG
CCGTATAGGTGTAAGAACGAAGATGGTCTCGGCACTGGCATACGCTGTCGCGAAAACCATTGGTAACTCCATAGCTGTGA
TCACTGTTGGCGAGAAACATGTTAGGCAAAGAAGGAATCTAAGCAATCTGGGCTCCGAGATACTTGGGATCCTCGAGAAG
CAATCTGAGCTCACAGCCTACGAGGTATGGAGGATCCTCGGGAGATACAGCCTTAGAGGAGTGTATAAGGCGCTTAAATC
TCTTGAGGAGCTCGGGCTTGTATGCGGCAAGCACGTGGTTAAGGGGGTTGGAAGGAAGGTGAAGACCTATTCCATATGTG
AGGACAGCTATATAGTTGAGTAA

Upstream 100 bases:

>100_bases
GAACCTGTACGCAGTGACATTCCATCCCGAGATAACGGGTGATATAAGGCTCTATAACTATATTATCCAGCAAGCCAAGA
GATAGTGTGAGGAATGCATC

Downstream 100 bases:

>100_bases
TCCGGCCTCGATGGATTTTTAATAGATTTAATGTAAAACCGGGCCTGTGAAACAATGATTTTATACATGAAAACCATTTA
AACCCTGTTTTTAAGACATA

Product: pyridoxal-5'-phosphate-dependent protein subunit beta

Products: L-threonine; phosphate

Alternate protein names: Pyridoxal-5-Phosphate-Dependent Protein Subunit Beta; Pyridoxal-5-Phosphate-Dependent Protein Beta Subunit; L-Threonine Synthase

Number of amino acids: Translated: 380; Mature: 379

Protein sequence:

>380_residues
MGQDTWVFSRCLKCGWSEKGLHLKCPVCGGVTVLEYERASLSIERNEASIWRYRGLLPGFPRKISMGEGLTPLRVVNGVL
VKNERKNPTGSYSDRASSIIASYLASTGRKIISVEYAEDFAYSVTYYTRRLVKGSIVIKDPFNADVDELISIHRAGFTIK
IGDTGEADIPYINPLTIEGLKTILLEIYERKLRAENVIVPVETGTLAFSLCKALKELSYLGIDPGYVIMGAMVKGAEKPW
LIEHCSNSVKIEEVDKAEALEALLELSRIGVRTKMVSALAYAVAKTIGNSIAVITVGEKHVRQRRNLSNLGSEILGILEK
QSELTAYEVWRILGRYSLRGVYKALKSLEELGLVCGKHVVKGVGRKVKTYSICEDSYIVE

Sequences:

>Translated_380_residues
MGQDTWVFSRCLKCGWSEKGLHLKCPVCGGVTVLEYERASLSIERNEASIWRYRGLLPGFPRKISMGEGLTPLRVVNGVL
VKNERKNPTGSYSDRASSIIASYLASTGRKIISVEYAEDFAYSVTYYTRRLVKGSIVIKDPFNADVDELISIHRAGFTIK
IGDTGEADIPYINPLTIEGLKTILLEIYERKLRAENVIVPVETGTLAFSLCKALKELSYLGIDPGYVIMGAMVKGAEKPW
LIEHCSNSVKIEEVDKAEALEALLELSRIGVRTKMVSALAYAVAKTIGNSIAVITVGEKHVRQRRNLSNLGSEILGILEK
QSELTAYEVWRILGRYSLRGVYKALKSLEELGLVCGKHVVKGVGRKVKTYSICEDSYIVE
>Mature_379_residues
GQDTWVFSRCLKCGWSEKGLHLKCPVCGGVTVLEYERASLSIERNEASIWRYRGLLPGFPRKISMGEGLTPLRVVNGVLV
KNERKNPTGSYSDRASSIIASYLASTGRKIISVEYAEDFAYSVTYYTRRLVKGSIVIKDPFNADVDELISIHRAGFTIKI
GDTGEADIPYINPLTIEGLKTILLEIYERKLRAENVIVPVETGTLAFSLCKALKELSYLGIDPGYVIMGAMVKGAEKPWL
IEHCSNSVKIEEVDKAEALEALLELSRIGVRTKMVSALAYAVAKTIGNSIAVITVGEKHVRQRRNLSNLGSEILGILEKQ
SELTAYEVWRILGRYSLRGVYKALKSLEELGLVCGKHVVKGVGRKVKTYSICEDSYIVE

Specific function: Unknown

COG id: COG0498

COG function: function code E; Threonine synthase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: 4.2.3.1

Molecular weight: Translated: 42119; Mature: 41987

Theoretical pI: Translated: 8.93; Mature: 8.93

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.1 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
2.1 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGQDTWVFSRCLKCGWSEKGLHLKCPVCGGVTVLEYERASLSIERNEASIWRYRGLLPGF
CCCCHHHHHHHHHCCCCCCCCEEECCCCCCEEEEEEECCCEEEECCCHHHHHHHCCCCCC
PRKISMGEGLTPLRVVNGVLVKNERKNPTGSYSDRASSIIASYLASTGRKIISVEYAEDF
CCCCCCCCCCCHHHHHCCHHEECCCCCCCCCCHHHHHHHHHHHHHHCCCEEEEEEEHHHH
AYSVTYYTRRLVKGSIVIKDPFNADVDELISIHRAGFTIKIGDTGEADIPYINPLTIEGL
HHHHHHHHHHHHCCCEEEECCCCCCHHHHHHHHHCCEEEEECCCCCCCCCCCCCEEHHHH
KTILLEIYERKLRAENVIVPVETGTLAFSLCKALKELSYLGIDPGYVIMGAMVKGAEKPW
HHHHHHHHHHHHHHCCEEEEECCCHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHCCCCCE
LIEHCSNSVKIEEVDKAEALEALLELSRIGVRTKMVSALAYAVAKTIGNSIAVITVGEKH
EHHHCCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECHHH
VRQRRNLSNLGSEILGILEKQSELTAYEVWRILGRYSLRGVYKALKSLEELGLVCGKHVV
HHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
KGVGRKVKTYSICEDSYIVE
HHCCCCCEEEEEECCCEECC
>Mature Secondary Structure 
GQDTWVFSRCLKCGWSEKGLHLKCPVCGGVTVLEYERASLSIERNEASIWRYRGLLPGF
CCCHHHHHHHHHCCCCCCCCEEECCCCCCEEEEEEECCCEEEECCCHHHHHHHCCCCCC
PRKISMGEGLTPLRVVNGVLVKNERKNPTGSYSDRASSIIASYLASTGRKIISVEYAEDF
CCCCCCCCCCCHHHHHCCHHEECCCCCCCCCCHHHHHHHHHHHHHHCCCEEEEEEEHHHH
AYSVTYYTRRLVKGSIVIKDPFNADVDELISIHRAGFTIKIGDTGEADIPYINPLTIEGL
HHHHHHHHHHHHCCCEEEECCCCCCHHHHHHHHHCCEEEEECCCCCCCCCCCCCEEHHHH
KTILLEIYERKLRAENVIVPVETGTLAFSLCKALKELSYLGIDPGYVIMGAMVKGAEKPW
HHHHHHHHHHHHHHCCEEEEECCCHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHCCCCCE
LIEHCSNSVKIEEVDKAEALEALLELSRIGVRTKMVSALAYAVAKTIGNSIAVITVGEKH
EHHHCCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECHHH
VRQRRNLSNLGSEILGILEKQSELTAYEVWRILGRYSLRGVYKALKSLEELGLVCGKHVV
HHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
KGVGRKVKTYSICEDSYIVE
HHCCCCCEEEEEECCCEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: O-phospho-L-homoserine; H2O

Specific reaction: O-phospho-L-homoserine + H2O = L-threonine + phosphate

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA