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The map label for this gene is pyrF [H]

Identifier: 218883788

GI number: 218883788

Start: 444536

End: 445210

Strand: Reverse

Name: pyrF [H]

Synonym: DKAM_0477

Alternate gene names: 218883788

Gene position: 445210-444536 (Counterclockwise)

Preceding gene: 218883789

Following gene: 218883787

Centisome position: 32.61

GC content: 46.96

Gene sequence:

>675_bases
ATGTTAGTTGTTGCAATTGACCCACCTGTAAGGGAGGAGAAAGACAAGAGGATAGATATCCTTGTAGGGGAAGTCGATGA
GTATGTTTCAGGCTATAAGATAGGTATCCCATTCATTCTAAAGCATGGTAAACAAGGGATTAGAAGGCTGAGGAGGCTCA
CGGAGAAGCCGATTATAGCGGATCTGAAGCTAGCGGATATAGGGGACATAATGAGTACTACGGTCAAGCATCTCGCAAAC
ACTGGTGTAAACGCTGTTATAGCCCACGCCTTTGTAGGATATAATGGTGCATTAGAGACCCTTGTGAAGACATCCATGGT
TACAGGGATAGGCGTTATATTAGTGGCATCCATGAGTCATGACGGCTCACGGGAATTCATAGATAAGCATATCGATGAAT
TCCTAGATCTAGCAGTGAAAGCAGGAGTTGAAGGCATTGTCGCACCAGCTACGAGGCCGAATGTAATCAGGTATGCGAGG
GAGAGGCTTGGCGGATCAATAAAGATATACTCGCCAGGTATAGGGATCCAGGGAGCTGAACCCGGCTCAGCACTATGCGT
GGGTGCCAATTACGAGATAGTAGGTAGGCTGATAACCGGTTCAAAGAATCCTGGTGAAGCAGCCAGGGAGGTTAGGGAGA
TACAGTTGAAGAGGTGGTCGAAGTGTCATGGATAA

Upstream 100 bases:

>100_bases
CAGAGCTATATCTGGATCCATACAGGATAAGAGAGGCACTTGAAAGGTATAGTAGCTAGAATATTTTTAAGTCCTGGTTT
ACATAGCTAAAGCGGGCTTC

Downstream 100 bases:

>100_bases
GCATTGAGCTCTATAAGAGGGGCATGGTGAAGATAGGGAGGTTCAAGCTATCCTCAGGCATAGAGAGCCCATTCTACATC
GATATGCGGAGACTATACAT

Product: Orotidine-5'-phosphate decarboxylase, PyrF

Products: NA

Alternate protein names: OMP decarboxylase; OMPDCase; OMPdecase [H]

Number of amino acids: Translated: 224; Mature: 224

Protein sequence:

>224_residues
MLVVAIDPPVREEKDKRIDILVGEVDEYVSGYKIGIPFILKHGKQGIRRLRRLTEKPIIADLKLADIGDIMSTTVKHLAN
TGVNAVIAHAFVGYNGALETLVKTSMVTGIGVILVASMSHDGSREFIDKHIDEFLDLAVKAGVEGIVAPATRPNVIRYAR
ERLGGSIKIYSPGIGIQGAEPGSALCVGANYEIVGRLITGSKNPGEAAREVREIQLKRWSKCHG

Sequences:

>Translated_224_residues
MLVVAIDPPVREEKDKRIDILVGEVDEYVSGYKIGIPFILKHGKQGIRRLRRLTEKPIIADLKLADIGDIMSTTVKHLAN
TGVNAVIAHAFVGYNGALETLVKTSMVTGIGVILVASMSHDGSREFIDKHIDEFLDLAVKAGVEGIVAPATRPNVIRYAR
ERLGGSIKIYSPGIGIQGAEPGSALCVGANYEIVGRLITGSKNPGEAAREVREIQLKRWSKCHG
>Mature_224_residues
MLVVAIDPPVREEKDKRIDILVGEVDEYVSGYKIGIPFILKHGKQGIRRLRRLTEKPIIADLKLADIGDIMSTTVKHLAN
TGVNAVIAHAFVGYNGALETLVKTSMVTGIGVILVASMSHDGSREFIDKHIDEFLDLAVKAGVEGIVAPATRPNVIRYAR
ERLGGSIKIYSPGIGIQGAEPGSALCVGANYEIVGRLITGSKNPGEAAREVREIQLKRWSKCHG

Specific function: Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP) [H]

COG id: COG0284

COG function: function code F; Orotidine-5'-phosphate decarboxylase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the OMP decarboxylase family. Type 1 subfamily [H]

Homologues:

None

Paralogues:

None

Copy number: 6,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013785
- InterPro:   IPR014732
- InterPro:   IPR001754
- InterPro:   IPR011060 [H]

Pfam domain/function: PF00215 OMPdecase [H]

EC number: =4.1.1.23 [H]

Molecular weight: Translated: 24217; Mature: 24217

Theoretical pI: Translated: 9.34; Mature: 9.34

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLVVAIDPPVREEKDKRIDILVGEVDEYVSGYKIGIPFILKHGKQGIRRLRRLTEKPIIA
CEEEEECCCCCCCCCCEEEEEECCHHHHHCCEECCHHHHHHCCHHHHHHHHHHHCCCCEE
DLKLADIGDIMSTTVKHLANTGVNAVIAHAFVGYNGALETLVKTSMVTGIGVILVASMSH
EEEHHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHEEECCC
DGSREFIDKHIDEFLDLAVKAGVEGIVAPATRPNVIRYARERLGGSIKIYSPGIGIQGAE
CCCHHHHHHHHHHHHHHHHHHCCCCEECCCCCCHHHHHHHHHHCCEEEEECCCCCCCCCC
PGSALCVGANYEIVGRLITGSKNPGEAAREVREIQLKRWSKCHG
CCCEEEECCCHHEEEEEECCCCCCCHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MLVVAIDPPVREEKDKRIDILVGEVDEYVSGYKIGIPFILKHGKQGIRRLRRLTEKPIIA
CEEEEECCCCCCCCCCEEEEEECCHHHHHCCEECCHHHHHHCCHHHHHHHHHHHCCCCEE
DLKLADIGDIMSTTVKHLANTGVNAVIAHAFVGYNGALETLVKTSMVTGIGVILVASMSH
EEEHHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHEEECCC
DGSREFIDKHIDEFLDLAVKAGVEGIVAPATRPNVIRYARERLGGSIKIYSPGIGIQGAE
CCCHHHHHHHHHHHHHHHHHHCCCCEECCCCCCHHHHHHHHHHCCEEEEECCCCCCCCCC
PGSALCVGANYEIVGRLITGSKNPGEAAREVREIQLKRWSKCHG
CCCEEEECCCHHEEEEEECCCCCCCHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10382966 [H]