Click here to switch to the map view.

The map label for this gene is dppA [H]

Identifier: 218883776

GI number: 218883776

Start: 433696

End: 434550

Strand: Direct

Name: dppA [H]

Synonym: DKAM_0465

Alternate gene names: 218883776

Gene position: 433696-434550 (Clockwise)

Preceding gene: 218883773

Following gene: 218883782

Centisome position: 31.77

GC content: 49.01

Gene sequence:

>855_bases
GTGCATGTGAAAGCATATATCTCAGTCGATCTCGAGGGATTACCGGGAGTATCCTCCTTGACGATGCTTAACCCAGGTAA
CACGCAATTTAATAGAGCTGTAAAAGTCCTGACAAGGCTATTAAACACTGTGATAGATGAACTGGCTACCCATGGCTTCG
ACGCAATATATGTCGCTGATAGCCATGGATTAATGACGAACATAGATTACTTGGAGTTGGACAGTAGGGCTGAGCTGGTA
CAGGGTTATCCACGTCAATTCAGCATGGTGACGCTACTGGACTCAAGCTTCAATGCAGCGCTATTCATCGGGTACCATGC
GGCAGCGGGGACCCCCCACGGAATATTGGATCACACAATGAGTGGTAGAACCTTCACGGAGATAAGGGTTAACGGTGAAA
GGGTCAGCGAGTTCATCTTGAATAGTCTGTACGCCGGAGAACACAACGTCCCCGTGGTACTCTTAGCCGGGGACGAACAC
CTCAGAGCCGAGGTTGAGAAATATTCTCCCTGGACGATCTTCGTCCCCCTGAAGAAGGGTGTATCAAGGTATAGTGCATC
ATACCCTGGCATAGACAAGGTTACAGAGGCTCTCAGAGAAGGGGTGTCTAAAGCAGTGAAGAAGCTGAAGAAAGGAGAGG
TCCAGCCTCTCAAGTGGAGCAAGCCGTTCAAGGCCGAGCTAACGCTCAGGGATTCCCTTATAGCCGATATACTCGAACCC
CTACCAATATTTAAAAGGATAGATGCATACAGGGTCGAGTTCGCAGCGAACACGGCCAGCGAGCTACTAGGCTACATAGA
GCTCATCGCCCACCTTGGCTATGGTGTAGACTCCTTGAAAAACAATATTAAATAG

Upstream 100 bases:

>100_bases
GCACCAGGTGCTCCCGGTTAGTTGAAAGCCGACATACGTTGAATATAAATGATAGAGTAAGATTAATTATTTATCGAGTA
ATAAAGCATGACAAGGGTGC

Downstream 100 bases:

>100_bases
CGTGTTACAGCCGAGGCAACACTCTTCAGGAGAGGGGGATGCCAGAGGACTGAAACTACTTTTGTTTACTGAAGACAGAT
GCATCCAGGTACTCACTCAC

Product: peptidase M55, D-aminopeptidase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 284; Mature: 284

Protein sequence:

>284_residues
MHVKAYISVDLEGLPGVSSLTMLNPGNTQFNRAVKVLTRLLNTVIDELATHGFDAIYVADSHGLMTNIDYLELDSRAELV
QGYPRQFSMVTLLDSSFNAALFIGYHAAAGTPHGILDHTMSGRTFTEIRVNGERVSEFILNSLYAGEHNVPVVLLAGDEH
LRAEVEKYSPWTIFVPLKKGVSRYSASYPGIDKVTEALREGVSKAVKKLKKGEVQPLKWSKPFKAELTLRDSLIADILEP
LPIFKRIDAYRVEFAANTASELLGYIELIAHLGYGVDSLKNNIK

Sequences:

>Translated_284_residues
MHVKAYISVDLEGLPGVSSLTMLNPGNTQFNRAVKVLTRLLNTVIDELATHGFDAIYVADSHGLMTNIDYLELDSRAELV
QGYPRQFSMVTLLDSSFNAALFIGYHAAAGTPHGILDHTMSGRTFTEIRVNGERVSEFILNSLYAGEHNVPVVLLAGDEH
LRAEVEKYSPWTIFVPLKKGVSRYSASYPGIDKVTEALREGVSKAVKKLKKGEVQPLKWSKPFKAELTLRDSLIADILEP
LPIFKRIDAYRVEFAANTASELLGYIELIAHLGYGVDSLKNNIK
>Mature_284_residues
MHVKAYISVDLEGLPGVSSLTMLNPGNTQFNRAVKVLTRLLNTVIDELATHGFDAIYVADSHGLMTNIDYLELDSRAELV
QGYPRQFSMVTLLDSSFNAALFIGYHAAAGTPHGILDHTMSGRTFTEIRVNGERVSEFILNSLYAGEHNVPVVLLAGDEH
LRAEVEKYSPWTIFVPLKKGVSRYSASYPGIDKVTEALREGVSKAVKKLKKGEVQPLKWSKPFKAELTLRDSLIADILEP
LPIFKRIDAYRVEFAANTASELLGYIELIAHLGYGVDSLKNNIK

Specific function: Hydrolyzes N-terminal residues in D-amino acid containing peptides. Among the tested substrates, the highest activities are with D-Ala-D-Ala and D-Ala-Gly-Gly. The physiological role is not clear [H]

COG id: COG2362

COG function: function code E; D-aminopeptidase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M55 family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR007035 [H]

Pfam domain/function: PF04951 Peptidase_M55 [H]

EC number: NA

Molecular weight: Translated: 31449; Mature: 31449

Theoretical pI: Translated: 6.81; Mature: 6.81

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
1.8 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MHVKAYISVDLEGLPGVSSLTMLNPGNTQFNRAVKVLTRLLNTVIDELATHGFDAIYVAD
CCEEEEEEEECCCCCCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEC
SHGLMTNIDYLELDSRAELVQGYPRQFSMVTLLDSSFNAALFIGYHAAAGTPHGILDHTM
CCCCEECCCEEEECCHHHHHCCCCCCEEEEEEECCCCCEEEEEEEECCCCCCCHHHHHCC
SGRTFTEIRVNGERVSEFILNSLYAGEHNVPVVLLAGDEHLRAEVEKYSPWTIFVPLKKG
CCCEEEEEEECHHHHHHHHHHHHHCCCCCCCEEEEECCHHHHHHHHHCCCEEEEEEHHHH
VSRYSASYPGIDKVTEALREGVSKAVKKLKKGEVQPLKWSKPFKAELTLRDSLIADILEP
HHHHCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCEEEEHHHHHHHHHHHH
LPIFKRIDAYRVEFAANTASELLGYIELIAHLGYGVDSLKNNIK
HHHHHHHHHHEEEEHHCCHHHHHHHHHHHHHHCCCHHHHHHCCC
>Mature Secondary Structure
MHVKAYISVDLEGLPGVSSLTMLNPGNTQFNRAVKVLTRLLNTVIDELATHGFDAIYVAD
CCEEEEEEEECCCCCCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEC
SHGLMTNIDYLELDSRAELVQGYPRQFSMVTLLDSSFNAALFIGYHAAAGTPHGILDHTM
CCCCEECCCEEEECCHHHHHCCCCCCEEEEEEECCCCCEEEEEEEECCCCCCCHHHHHCC
SGRTFTEIRVNGERVSEFILNSLYAGEHNVPVVLLAGDEHLRAEVEKYSPWTIFVPLKKG
CCCEEEEEEECHHHHHHHHHHHHHCCCCCCCEEEEECCHHHHHHHHHCCCEEEEEEHHHH
VSRYSASYPGIDKVTEALREGVSKAVKKLKKGEVQPLKWSKPFKAELTLRDSLIADILEP
HHHHCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCEEEEHHHHHHHHHHHH
LPIFKRIDAYRVEFAANTASELLGYIELIAHLGYGVDSLKNNIK
HHHHHHHHHHEEEEHHCCHHHHHHHHHHHHHHCCCHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1766370; 9384377 [H]