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The map label for this gene is appB [H]

Identifier: 218883707

GI number: 218883707

Start: 367211

End: 368317

Strand: Reverse

Name: appB [H]

Synonym: DKAM_0396

Alternate gene names: 218883707

Gene position: 368317-367211 (Counterclockwise)

Preceding gene: 218883708

Following gene: 218883706

Centisome position: 26.98

GC content: 43.18

Gene sequence:

>1107_bases
ATGCCGGGAGCCGGCTACTATATAGCTAGGCGTGGAGTTGTTTTACTGGTTTCCTATGTTGCGATAATTATAATAATAGC
TGCTATACTGGAGCTATCAGGTTATGCAACCCAGATATACCAGGCAGTAATCAATGAACTTGTGAGGGCAGATGTAGATG
CATTGGTGAAAGCACGTCAGGGCCAAGTAGATCCAGCATACATCCAAGAGTATCGTCAAAACAGAACCATAGAGTATATG
AAGCAGTATGGGCTGATAGATGAAAATGGTAATCCGGTCCCTTCATACGTGAGAATGTGGAAGCTCGCATTTAATGCTTT
AACATTTAACTTCGGTAAGACAAAAGAGGATCTCGTTGCAATGGTTGTTCCCACTATGCCCCCTGCAAGCATCACTTACA
TAATATCGGTAGTTCTACCTAGGACAATAATAGTTGTCACTGTTGGCGAATTAATAGTAGTCGCAATAGCGTTACTGGTT
GGTCCTAGAATAGCATATAGACACGGTACCTTCTTGGATAGGGTAGTGGTGGCTTACGCAGCTCTTACTAGTGCTATACC
ACTATGGTGGCTTGCAATGTTGTTTATAAGGGTGTTCGGATACCAGCTTGGATGGTTCCCTACGAGTCTAAGAGGAGTTA
CCACACCGCTTAACAACTTCTGGTCTAACCCTGCTCAGAACTTTGTAACTATACTATGGTATATAACGCCGCCGCTTACA
GTATTCACGATTATCTCGCTTGGTGGATGGCTATATGGTGTTAGAGCAATGGTTTTAAGGATAGTTAGGGAAGACTACGT
AATGGTAGCGAAAGCAAAGGGGTTGCCCGAGAGAGATATTACAAGGAAATACGTGATGAGGCCCTCACTAGCACCAATAT
TGACTAATGTGATACTAGCGTTGGCCGGTACCCTTGGCGGTATGATTATCACTGAATCCGTATTCGACTGGCCTGGAATG
GGAACACTATATTATGCAGCGATAACGACGGGCGATGCTGAAACTATTGTAGCATTATTCGTAATATATGTAGGAGTCTA
CTTGATAGCAAGGTTTATACTTGAAATATTATACGTATTAGTAGATCCCAGGGTTCGTGTGAGGTAG

Upstream 100 bases:

>100_bases
GAGATAATATAATGGCATAGAACCACATGACTGGGGAGATATGTTTGGTATGTAATGTATTTATAAGCCTCTGGGATTTA
TCAGGATTAATGGTGGTTGA

Downstream 100 bases:

>100_bases
GGTGAGATCACGATGGCGGCCACAAGGGAGTTGACATTTAAAGATAAATTAGTTCTCAGAGTAGTGAATCCCTTAAAGGG
TGTTCTAAAGGAAATATGGG

Product: binding-protein-dependent transport systems inner membrane component

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 368; Mature: 367

Protein sequence:

>368_residues
MPGAGYYIARRGVVLLVSYVAIIIIIAAILELSGYATQIYQAVINELVRADVDALVKARQGQVDPAYIQEYRQNRTIEYM
KQYGLIDENGNPVPSYVRMWKLAFNALTFNFGKTKEDLVAMVVPTMPPASITYIISVVLPRTIIVVTVGELIVVAIALLV
GPRIAYRHGTFLDRVVVAYAALTSAIPLWWLAMLFIRVFGYQLGWFPTSLRGVTTPLNNFWSNPAQNFVTILWYITPPLT
VFTIISLGGWLYGVRAMVLRIVREDYVMVAKAKGLPERDITRKYVMRPSLAPILTNVILALAGTLGGMIITESVFDWPGM
GTLYYAAITTGDAETIVALFVIYVGVYLIARFILEILYVLVDPRVRVR

Sequences:

>Translated_368_residues
MPGAGYYIARRGVVLLVSYVAIIIIIAAILELSGYATQIYQAVINELVRADVDALVKARQGQVDPAYIQEYRQNRTIEYM
KQYGLIDENGNPVPSYVRMWKLAFNALTFNFGKTKEDLVAMVVPTMPPASITYIISVVLPRTIIVVTVGELIVVAIALLV
GPRIAYRHGTFLDRVVVAYAALTSAIPLWWLAMLFIRVFGYQLGWFPTSLRGVTTPLNNFWSNPAQNFVTILWYITPPLT
VFTIISLGGWLYGVRAMVLRIVREDYVMVAKAKGLPERDITRKYVMRPSLAPILTNVILALAGTLGGMIITESVFDWPGM
GTLYYAAITTGDAETIVALFVIYVGVYLIARFILEILYVLVDPRVRVR
>Mature_367_residues
PGAGYYIARRGVVLLVSYVAIIIIIAAILELSGYATQIYQAVINELVRADVDALVKARQGQVDPAYIQEYRQNRTIEYMK
QYGLIDENGNPVPSYVRMWKLAFNALTFNFGKTKEDLVAMVVPTMPPASITYIISVVLPRTIIVVTVGELIVVAIALLVG
PRIAYRHGTFLDRVVVAYAALTSAIPLWWLAMLFIRVFGYQLGWFPTSLRGVTTPLNNFWSNPAQNFVTILWYITPPLTV
FTIISLGGWLYGVRAMVLRIVREDYVMVAKAKGLPERDITRKYVMRPSLAPILTNVILALAGTLGGMIITESVFDWPGMG
TLYYAAITTGDAETIVALFVIYVGVYLIARFILEILYVLVDPRVRVR

Specific function: This protein is a component of an oligopeptide permease, a binding protein-dependent transport system. This APP system can completely substitute for the OPP system in both sporulation and genetic competence, though, unlike OPP, is incapable of transportin

COG id: COG0601

COG function: function code EP; ABC-type dipeptide/oligopeptide/nickel transport systems, permease components

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transmembrane type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI1787053, Length=299, Percent_Identity=26.7558528428094, Blast_Score=89, Evalue=4e-19,
Organism=Escherichia coli, GI1788504, Length=316, Percent_Identity=26.5822784810127, Blast_Score=86, Evalue=3e-18,
Organism=Escherichia coli, GI1789965, Length=228, Percent_Identity=25, Blast_Score=84, Evalue=1e-17,
Organism=Escherichia coli, GI1787497, Length=202, Percent_Identity=22.7722772277228, Blast_Score=77, Evalue=2e-15,
Organism=Escherichia coli, GI1789888, Length=203, Percent_Identity=27.0935960591133, Blast_Score=77, Evalue=2e-15,
Organism=Escherichia coli, GI1787550, Length=234, Percent_Identity=26.0683760683761, Blast_Score=66, Evalue=3e-12,
Organism=Escherichia coli, GI1787761, Length=207, Percent_Identity=28.0193236714976, Blast_Score=62, Evalue=5e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000515 [H]

Pfam domain/function: PF00528 BPD_transp_1 [H]

EC number: NA

Molecular weight: Translated: 41112; Mature: 40981

Theoretical pI: Translated: 9.69; Mature: 9.69

Prosite motif: PS50928 ABC_TM1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPGAGYYIARRGVVLLVSYVAIIIIIAAILELSGYATQIYQAVINELVRADVDALVKARQ
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHC
GQVDPAYIQEYRQNRTIEYMKQYGLIDENGNPVPSYVRMWKLAFNALTFNFGKTKEDLVA
CCCCHHHHHHHHHCCHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCHHHHHH
MVVPTMPPASITYIISVVLPRTIIVVTVGELIVVAIALLVGPRIAYRHGTFLDRVVVAYA
HEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHCCHHHHHHHHHHH
ALTSAIPLWWLAMLFIRVFGYQLGWFPTSLRGVTTPLNNFWSNPAQNFVTILWYITPPLT
HHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHCCCCHHHHHCCCHHHHHEEEEECCCHHH
VFTIISLGGWLYGVRAMVLRIVREDYVMVAKAKGLPERDITRKYVMRPSLAPILTNVILA
HHHHHHHHHHHHHHHHHHHHHHHHHHHEEEECCCCCCHHHHHHHHHCCCHHHHHHHHHHH
LAGTLGGMIITESVFDWPGMGTLYYAAITTGDAETIVALFVIYVGVYLIARFILEILYVL
HHHHHCCHHHHHHHHCCCCCCCEEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VDPRVRVR
HCCCCCCC
>Mature Secondary Structure 
PGAGYYIARRGVVLLVSYVAIIIIIAAILELSGYATQIYQAVINELVRADVDALVKARQ
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHC
GQVDPAYIQEYRQNRTIEYMKQYGLIDENGNPVPSYVRMWKLAFNALTFNFGKTKEDLVA
CCCCHHHHHHHHHCCHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCHHHHHH
MVVPTMPPASITYIISVVLPRTIIVVTVGELIVVAIALLVGPRIAYRHGTFLDRVVVAYA
HEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHCCHHHHHHHHHHH
ALTSAIPLWWLAMLFIRVFGYQLGWFPTSLRGVTTPLNNFWSNPAQNFVTILWYITPPLT
HHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHCCCCHHHHHCCCHHHHHEEEEECCCHHH
VFTIISLGGWLYGVRAMVLRIVREDYVMVAKAKGLPERDITRKYVMRPSLAPILTNVILA
HHHHHHHHHHHHHHHHHHHHHHHHHHHEEEECCCCCCHHHHHHHHHCCCHHHHHHHHHHH
LAGTLGGMIITESVFDWPGMGTLYYAAITTGDAETIVALFVIYVGVYLIARFILEILYVL
HHHHHCCHHHHHHHHCCCCCCCEEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VDPRVRVR
HCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7997159; 9384377 [H]