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The map label for this gene is appC [H]

Identifier: 218883706

GI number: 218883706

Start: 365267

End: 367198

Strand: Reverse

Name: appC [H]

Synonym: DKAM_0395

Alternate gene names: 218883706

Gene position: 367198-365267 (Counterclockwise)

Preceding gene: 218883707

Following gene: 218883704

Centisome position: 26.9

GC content: 41.3

Gene sequence:

>1932_bases
ATGGCGGCCACAAGGGAGTTGACATTTAAAGATAAATTAGTTCTCAGAGTAGTGAATCCCTTAAAGGGTGTTCTAAAGGA
AATATGGGGTATGACAACAGGTAAGATAGCATTATTACTATTATCAATCCTAATAGCTGTCTCTGTGTCAGCTGCATCAA
CAATGCCTCCTGGCTTCCTGGACTCATGGCAGAGCGCATCATTCTGGGAGGATAACCCCGTCATAGTACCACCAGATTGG
GTGAAATACTTTGGTGCAAAAGTAGCCCCAAGCATAGTTGAGGAGAAATCGAAGCCCGATGTCACGCCTCAATGGGATCC
ATCAACAGGCATACTTACATTAACATATAGGTTTGAATATACTTTAACCGACCCAGTATTTCCACAGGACTATTATTTCG
CAGTCTACGGTATAAAATCCTATGATAACATTACCCCGATAATAACTATAAGTGTTGAGCGCCCGGACGGTATTACAAGT
GTTTTATGGCAGGAGAACATATTTATAAATAACACTAACGCTGATGTTACATCAATTTACAAGACAGACCCGAAGAAAAT
AAAGATGGATGATCTTGTATCGGAAATATTTGCGAAATATAATATCACAGTACCTCCCAATATAATCGGAGAAAACTACA
TGATACAGGCAATATCAAGCTCGTTGCTACGTGATAGAGTAGTTTCAAAGATATCGCAGCCTTCAACAGCTCTCTCGATC
TTCCAGAAACCAGTTAACGTGGAGAACTGGGTAACCGTGTTGAGAAGTGAACAAAGACCAGTACTTGAGGAAATAAACAA
CTTGCTAAAGAACATCCGAGGCTCCATCAGTAACGATCCAGCCAACATATTACCGCTCATCAATAACGCCATATCTAATG
TTACATTCCTTATAAACAACCTGGATAAAATAACATTCAGTGATCTCTATGAGACACTTCAAAACGTTTCAACGCTCCTA
AATAACGCATATAAGTTAGCTATGAGTGAAAACTACCCCTCGGTAGTTGTAACTAATATAAATGATGCGAAGAGCAGAAT
AGACAAATATCTTGACTCACTAAAGGTCACTGTTTCATTCATTGGTATAAGCCCTGAGTTCGAGATATTAACGGGAGCAT
ATAGGTTCGAAGTAAATATTACTTATCCAGGTGTCAGAACATATCCGTCTAACCCGCAGTCGCTAATAAGCTATGTGAAA
TTCACTGTGAAGGGCTCAGTAAAGGGAACACTTGGCACTATAAATAATGGTGCTGACTTAGCCACGCTACTATACTATGG
TTTCCCAATAGCCTTACTAATAGGATTAATAGCATCGGTATCTTCAACGCTCATAGGCGTTATAGCTGGTATTATAAGTG
GATACTATGGTGGATGGATTGATGAGGTTATCCAGAGAATAATAGATATATTGAATAACATACCATTCCTCCCATTAATG
ATAATTATTGGTACAGCCGCAATGAAAGTGCTTCCACCCGGCACACAGAAATCCTTCTACATAATAATGCTATATGTTGC
AATACTGATAATATTCAGCTGGGCTGGTCTAGCAATAGTTGTACGCTCAATGACGCTCAGCATAAAGGAGGAACCATATA
TCGAGGCTGCCAAGGCTATGGGTGCATCTAATACGCGTATAATATTCTACCATATATTTCCCCAGGTAATGATGTATGCT
GTTGCAACCCTAGTATATAATGTCCCAAGCGCGATACTAACGGAAGCCGGGCTGAGTGTACTAGGACTCAGGCATGGATG
GCCTACATGGGGTGCTGTGCTAGCCGAGGCGAGGGCGGCTGGACCAGTTGGATATGCTGCATGGTGGTGGATACTGCCGC
CCGGACTATTACTCTCTCTGACATCACTAACATTCGTGCTACTCGGGTTAGCAGTTGAAAAAATAGTTGAGCCACGCTTA
AGGACTCTATAG

Upstream 100 bases:

>100_bases
CGTAATATATGTAGGAGTCTACTTGATAGCAAGGTTTATACTTGAAATATTATACGTATTAGTAGATCCCAGGGTTCGTG
TGAGGTAGGGTGAGATCACG

Downstream 100 bases:

>100_bases
TTACATTGTTTTTTAATCCCCCTCCCGCCATATATGTAAGGATTAATATACATCCTGGTTGAAGAGGTTTTGCCACGATC
TAAACAGGTATTCTTTTAAA

Product: binding-protein-dependent transport systems inner membrane component

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 643; Mature: 642

Protein sequence:

>643_residues
MAATRELTFKDKLVLRVVNPLKGVLKEIWGMTTGKIALLLLSILIAVSVSAASTMPPGFLDSWQSASFWEDNPVIVPPDW
VKYFGAKVAPSIVEEKSKPDVTPQWDPSTGILTLTYRFEYTLTDPVFPQDYYFAVYGIKSYDNITPIITISVERPDGITS
VLWQENIFINNTNADVTSIYKTDPKKIKMDDLVSEIFAKYNITVPPNIIGENYMIQAISSSLLRDRVVSKISQPSTALSI
FQKPVNVENWVTVLRSEQRPVLEEINNLLKNIRGSISNDPANILPLINNAISNVTFLINNLDKITFSDLYETLQNVSTLL
NNAYKLAMSENYPSVVVTNINDAKSRIDKYLDSLKVTVSFIGISPEFEILTGAYRFEVNITYPGVRTYPSNPQSLISYVK
FTVKGSVKGTLGTINNGADLATLLYYGFPIALLIGLIASVSSTLIGVIAGIISGYYGGWIDEVIQRIIDILNNIPFLPLM
IIIGTAAMKVLPPGTQKSFYIIMLYVAILIIFSWAGLAIVVRSMTLSIKEEPYIEAAKAMGASNTRIIFYHIFPQVMMYA
VATLVYNVPSAILTEAGLSVLGLRHGWPTWGAVLAEARAAGPVGYAAWWWILPPGLLLSLTSLTFVLLGLAVEKIVEPRL
RTL

Sequences:

>Translated_643_residues
MAATRELTFKDKLVLRVVNPLKGVLKEIWGMTTGKIALLLLSILIAVSVSAASTMPPGFLDSWQSASFWEDNPVIVPPDW
VKYFGAKVAPSIVEEKSKPDVTPQWDPSTGILTLTYRFEYTLTDPVFPQDYYFAVYGIKSYDNITPIITISVERPDGITS
VLWQENIFINNTNADVTSIYKTDPKKIKMDDLVSEIFAKYNITVPPNIIGENYMIQAISSSLLRDRVVSKISQPSTALSI
FQKPVNVENWVTVLRSEQRPVLEEINNLLKNIRGSISNDPANILPLINNAISNVTFLINNLDKITFSDLYETLQNVSTLL
NNAYKLAMSENYPSVVVTNINDAKSRIDKYLDSLKVTVSFIGISPEFEILTGAYRFEVNITYPGVRTYPSNPQSLISYVK
FTVKGSVKGTLGTINNGADLATLLYYGFPIALLIGLIASVSSTLIGVIAGIISGYYGGWIDEVIQRIIDILNNIPFLPLM
IIIGTAAMKVLPPGTQKSFYIIMLYVAILIIFSWAGLAIVVRSMTLSIKEEPYIEAAKAMGASNTRIIFYHIFPQVMMYA
VATLVYNVPSAILTEAGLSVLGLRHGWPTWGAVLAEARAAGPVGYAAWWWILPPGLLLSLTSLTFVLLGLAVEKIVEPRL
RTL
>Mature_642_residues
AATRELTFKDKLVLRVVNPLKGVLKEIWGMTTGKIALLLLSILIAVSVSAASTMPPGFLDSWQSASFWEDNPVIVPPDWV
KYFGAKVAPSIVEEKSKPDVTPQWDPSTGILTLTYRFEYTLTDPVFPQDYYFAVYGIKSYDNITPIITISVERPDGITSV
LWQENIFINNTNADVTSIYKTDPKKIKMDDLVSEIFAKYNITVPPNIIGENYMIQAISSSLLRDRVVSKISQPSTALSIF
QKPVNVENWVTVLRSEQRPVLEEINNLLKNIRGSISNDPANILPLINNAISNVTFLINNLDKITFSDLYETLQNVSTLLN
NAYKLAMSENYPSVVVTNINDAKSRIDKYLDSLKVTVSFIGISPEFEILTGAYRFEVNITYPGVRTYPSNPQSLISYVKF
TVKGSVKGTLGTINNGADLATLLYYGFPIALLIGLIASVSSTLIGVIAGIISGYYGGWIDEVIQRIIDILNNIPFLPLMI
IIGTAAMKVLPPGTQKSFYIIMLYVAILIIFSWAGLAIVVRSMTLSIKEEPYIEAAKAMGASNTRIIFYHIFPQVMMYAV
ATLVYNVPSAILTEAGLSVLGLRHGWPTWGAVLAEARAAGPVGYAAWWWILPPGLLLSLTSLTFVLLGLAVEKIVEPRLR
TL

Specific function: This protein is a component of an oligopeptide permease, a binding protein-dependent transport system. This APP system can completely substitute for the OPP system in both sporulation and genetic competence, though, unlike OPP, is incapable of transportin

COG id: COG1173

COG function: function code EP; ABC-type dipeptide/oligopeptide/nickel transport systems, permease components

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transmembrane type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI1787054, Length=256, Percent_Identity=31.25, Blast_Score=105, Evalue=1e-23,
Organism=Escherichia coli, GI1788505, Length=238, Percent_Identity=32.7731092436975, Blast_Score=103, Evalue=3e-23,
Organism=Escherichia coli, GI1787498, Length=236, Percent_Identity=33.4745762711864, Blast_Score=99, Evalue=7e-22,
Organism=Escherichia coli, GI1787760, Length=233, Percent_Identity=31.7596566523605, Blast_Score=92, Evalue=8e-20,
Organism=Escherichia coli, GI1789964, Length=268, Percent_Identity=29.8507462686567, Blast_Score=86, Evalue=8e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000515 [H]

Pfam domain/function: PF00528 BPD_transp_1 [H]

EC number: NA

Molecular weight: Translated: 71078; Mature: 70947

Theoretical pI: Translated: 6.60; Mature: 6.60

Prosite motif: PS50928 ABC_TM1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAATRELTFKDKLVLRVVNPLKGVLKEIWGMTTGKIALLLLSILIAVSVSAASTMPPGFL
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCCCCCHH
DSWQSASFWEDNPVIVPPDWVKYFGAKVAPSIVEEKSKPDVTPQWDPSTGILTLTYRFEY
HCCCCCCCCCCCCEEECCHHHHHCCCCCCHHHHHCCCCCCCCCCCCCCCCEEEEEEEEEE
TLTDPVFPQDYYFAVYGIKSYDNITPIITISVERPDGITSVLWQENIFINNTNADVTSIY
EECCCCCCCCEEEEEEEECCCCCCCEEEEEEEECCCCHHHHHCCCCEEEECCCCCEEEEE
KTDPKKIKMDDLVSEIFAKYNITVPPNIIGENYMIQAISSSLLRDRVVSKISQPSTALSI
CCCCCCCCHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCHHHHHH
FQKPVNVENWVTVLRSEQRPVLEEINNLLKNIRGSISNDPANILPLINNAISNVTFLINN
HHCCCCHHHHHHHHHCCCCCHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHC
LDKITFSDLYETLQNVSTLLNNAYKLAMSENYPSVVVTNINDAKSRIDKYLDSLKVTVSF
CCCCHHHHHHHHHHHHHHHHHHHHEEEECCCCCCEEEECCCHHHHHHHHHHHHHEEEEEE
IGISPEFEILTGAYRFEVNITYPGVRTYPSNPQSLISYVKFTVKGSVKGTLGTINNGADL
EECCCCCEEEEEEEEEEEEEECCCCCCCCCCHHHHHHHHHHHEECCCCEECCCCCCCHHH
ATLLYYGFPIALLIGLIASVSSTLIGVIAGIISGYYGGWIDEVIQRIIDILNNIPFLPLM
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCCHHHHH
IIIGTAAMKVLPPGTQKSFYIIMLYVAILIIFSWAGLAIVVRSMTLSIKEEPYIEAAKAM
HHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHC
GASNTRIIFYHIFPQVMMYAVATLVYNVPSAILTEAGLSVLGLRHGWPTWGAVLAEARAA
CCCCCEEEEEHHHHHHHHHHHHHHHHHCCHHHHHHCCHHHEECCCCCCHHHHHHHHHHCC
GPVGYAAWWWILPPGLLLSLTSLTFVLLGLAVEKIVEPRLRTL
CCCCHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHCHHHHCC
>Mature Secondary Structure 
AATRELTFKDKLVLRVVNPLKGVLKEIWGMTTGKIALLLLSILIAVSVSAASTMPPGFL
CCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCCCCCHH
DSWQSASFWEDNPVIVPPDWVKYFGAKVAPSIVEEKSKPDVTPQWDPSTGILTLTYRFEY
HCCCCCCCCCCCCEEECCHHHHHCCCCCCHHHHHCCCCCCCCCCCCCCCCEEEEEEEEEE
TLTDPVFPQDYYFAVYGIKSYDNITPIITISVERPDGITSVLWQENIFINNTNADVTSIY
EECCCCCCCCEEEEEEEECCCCCCCEEEEEEEECCCCHHHHHCCCCEEEECCCCCEEEEE
KTDPKKIKMDDLVSEIFAKYNITVPPNIIGENYMIQAISSSLLRDRVVSKISQPSTALSI
CCCCCCCCHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCHHHHHH
FQKPVNVENWVTVLRSEQRPVLEEINNLLKNIRGSISNDPANILPLINNAISNVTFLINN
HHCCCCHHHHHHHHHCCCCCHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHC
LDKITFSDLYETLQNVSTLLNNAYKLAMSENYPSVVVTNINDAKSRIDKYLDSLKVTVSF
CCCCHHHHHHHHHHHHHHHHHHHHEEEECCCCCCEEEECCCHHHHHHHHHHHHHEEEEEE
IGISPEFEILTGAYRFEVNITYPGVRTYPSNPQSLISYVKFTVKGSVKGTLGTINNGADL
EECCCCCEEEEEEEEEEEEEECCCCCCCCCCHHHHHHHHHHHEECCCCEECCCCCCCHHH
ATLLYYGFPIALLIGLIASVSSTLIGVIAGIISGYYGGWIDEVIQRIIDILNNIPFLPLM
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCCHHHHH
IIIGTAAMKVLPPGTQKSFYIIMLYVAILIIFSWAGLAIVVRSMTLSIKEEPYIEAAKAM
HHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHC
GASNTRIIFYHIFPQVMMYAVATLVYNVPSAILTEAGLSVLGLRHGWPTWGAVLAEARAA
CCCCCEEEEEHHHHHHHHHHHHHHHHHCCHHHHHHCCHHHEECCCCCCHHHHHHHHHHCC
GPVGYAAWWWILPPGLLLSLTSLTFVLLGLAVEKIVEPRLRTL
CCCCHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHCHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7997159; 9384377 [H]