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The map label for this gene is crl [H]

Identifier: 218710380

GI number: 218710380

Start: 2586493

End: 2586900

Strand: Reverse

Name: crl [H]

Synonym: VS_2417

Alternate gene names: 218710380

Gene position: 2586900-2586493 (Counterclockwise)

Preceding gene: 218710381

Following gene: 218710379

Centisome position: 78.41

GC content: 41.91

Gene sequence:

>408_bases
TTGAAATGGAGATTCAATATGTCAGAAGTGACACAACAACCTACGCATTATCGCTTGTTAAATGTTTTAAAGGCTATTGG
CCCTTACTTAAGGGAGCCTCAATCAGAAGAAGGCCACTATATTTTTGATTGCTTGTCTGTGTGTGTTAACGATAAAAAAT
CGCCAGAAGAACGTGAGTTTTGGGGCTGGTGGTTGGAGTTGGATAAGTCGGAAGAAGGATTTTCGGCGAAGTACAACACG
GGTAAATACAACATCGATGGTAACTGGGATCCTTTGCCATTACCTAAAAAGGCGATCGCTGAGGTCTCTCGAACTCAAGA
AGCCTTTCACCAAAAGCTGGTTGATGAACTTCAAAAGAAATTTGAAATCGGCGTTCAGTTAGACGAAGAGTCTGTCGAAT
TCGTCTGA

Upstream 100 bases:

>100_bases
GAAAAGTGTACAAAGTAAGTACCTGATACTCAGAGGTAATTTATAAAATCCAATTGCGTAGTTTCTACGTATAACAGTCT
GAGTAACGTCATTCTTAACA

Downstream 100 bases:

>100_bases
TTTTAAAGGTTACTCTTCTATATAAAGCAAAAAGGTGCGATTTCGCACCTTTTCTGCTTGTGAATTCCCCTTTTGATTGC
TAAAACATCACCTCTTATTT

Product: DNA-binding transcriptional regulator Crl

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 135; Mature: 135

Protein sequence:

>135_residues
MKWRFNMSEVTQQPTHYRLLNVLKAIGPYLREPQSEEGHYIFDCLSVCVNDKKSPEEREFWGWWLELDKSEEGFSAKYNT
GKYNIDGNWDPLPLPKKAIAEVSRTQEAFHQKLVDELQKKFEIGVQLDEESVEFV

Sequences:

>Translated_135_residues
MKWRFNMSEVTQQPTHYRLLNVLKAIGPYLREPQSEEGHYIFDCLSVCVNDKKSPEEREFWGWWLELDKSEEGFSAKYNT
GKYNIDGNWDPLPLPKKAIAEVSRTQEAFHQKLVDELQKKFEIGVQLDEESVEFV
>Mature_135_residues
MKWRFNMSEVTQQPTHYRLLNVLKAIGPYLREPQSEEGHYIFDCLSVCVNDKKSPEEREFWGWWLELDKSEEGFSAKYNT
GKYNIDGNWDPLPLPKKAIAEVSRTQEAFHQKLVDELQKKFEIGVQLDEESVEFV

Specific function: Binds to the sigma-S subunit of RNA polymerase, activating expression of sigma-S-regulated genes. Stimulates RNA polymerase holoenzyme formation and may bind to several other sigma factors, such as sigma-70 and sigma-32 [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the crl family [H]

Homologues:

Organism=Escherichia coli, GI1786435, Length=122, Percent_Identity=37.7049180327869, Blast_Score=95, Evalue=2e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR009986 [H]

Pfam domain/function: PF07417 Crl [H]

EC number: NA

Molecular weight: Translated: 15928; Mature: 15928

Theoretical pI: Translated: 4.75; Mature: 4.75

Prosite motif: PS00213 LIPOCALIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKWRFNMSEVTQQPTHYRLLNVLKAIGPYLREPQSEEGHYIFDCLSVCVNDKKSPEEREF
CCCCCCHHHHHCCCHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHCCCCCCCHHHH
WGWWLELDKSEEGFSAKYNTGKYNIDGNWDPLPLPKKAIAEVSRTQEAFHQKLVDELQKK
HHHEEEECCCCCCCCCCCCCCEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
FEIGVQLDEESVEFV
HHCCCEECCCCCCCC
>Mature Secondary Structure
MKWRFNMSEVTQQPTHYRLLNVLKAIGPYLREPQSEEGHYIFDCLSVCVNDKKSPEEREF
CCCCCCHHHHHCCCHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHCCCCCCCHHHH
WGWWLELDKSEEGFSAKYNTGKYNIDGNWDPLPLPKKAIAEVSRTQEAFHQKLVDELQKK
HHHEEEECCCCCCCCCCCCCCEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
FEIGVQLDEESVEFV
HHCCCEECCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA