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The map label for this gene is gmhB [H]

Identifier: 218710345

GI number: 218710345

Start: 2549563

End: 2550114

Strand: Reverse

Name: gmhB [H]

Synonym: VS_2381

Alternate gene names: 218710345

Gene position: 2550114-2549563 (Counterclockwise)

Preceding gene: 218710351

Following gene: 218710344

Centisome position: 77.29

GC content: 43.66

Gene sequence:

>552_bases
TTGTCTAAACCTGCTGTTTTTTTAGATCGTGATGGTGTGATTAACGTTGATCACGGCTACGTACATGATGAACATGACTT
TGAATACATCGATGGTGTGTTTGAAGCGGCGAAAGCGTTTAAAGATATGGGTTATTTATTGGTGTTAGTGACCAACCAAT
CTGGTATTGCTCGCGGCATGTTTAGTGAAGACCGTTTTCTTTCTCTAACGCAGTGGATGGATTGGAACTTTGTTGATAAC
GGCGTTGAGCTAGATGGTATTTATTACTGCCCGCACCACGCTGAGCACGGTGTTGGTGACTACAAACAAGATTGTGAATG
TCGTAAACCAAAGCCAGGCATGTTCATTTCTGCGCGTGACTTTCTGAAGATTGATATGGCTAACTCGGTCATGATCGGCG
ATAAAGCTGAAGACATGATGGCTGCAGAAGCGGCGGGTGTTGGCACTAAAGTACTGGTAAGAACCGGTAAGCCAATCACT
GAAAAAGGTGAAGCGCTTGCAAGTGTCGTGCTTGACAGTATTAAAGATGTACCAGCATTCTTAAAAGGTTAA

Upstream 100 bases:

>100_bases
AAACAAATCGTTAACGAACGCAAAACTAAATAGATAGTGATGAAGCAAATAAAGCGTGTAATAATTAATGATTAATAGAG
AGTTGATAGAGAACTGAATT

Downstream 100 bases:

>100_bases
GACACTAAGTCTCTTTCACTTAGATATAAGTGTTATTCACTATATAAAGATGAGGAACGCAGTATGAAAGCATTGTTGAT
AGCATCTCTATGTACGGTAG

Product: D,D-heptose 1,7-bisphosphate phosphatase

Products: NA

Alternate protein names: D-glycero-D-manno-heptose 1,7-bisphosphate phosphatase [H]

Number of amino acids: Translated: 183; Mature: 182

Protein sequence:

>183_residues
MSKPAVFLDRDGVINVDHGYVHDEHDFEYIDGVFEAAKAFKDMGYLLVLVTNQSGIARGMFSEDRFLSLTQWMDWNFVDN
GVELDGIYYCPHHAEHGVGDYKQDCECRKPKPGMFISARDFLKIDMANSVMIGDKAEDMMAAEAAGVGTKVLVRTGKPIT
EKGEALASVVLDSIKDVPAFLKG

Sequences:

>Translated_183_residues
MSKPAVFLDRDGVINVDHGYVHDEHDFEYIDGVFEAAKAFKDMGYLLVLVTNQSGIARGMFSEDRFLSLTQWMDWNFVDN
GVELDGIYYCPHHAEHGVGDYKQDCECRKPKPGMFISARDFLKIDMANSVMIGDKAEDMMAAEAAGVGTKVLVRTGKPIT
EKGEALASVVLDSIKDVPAFLKG
>Mature_182_residues
SKPAVFLDRDGVINVDHGYVHDEHDFEYIDGVFEAAKAFKDMGYLLVLVTNQSGIARGMFSEDRFLSLTQWMDWNFVDNG
VELDGIYYCPHHAEHGVGDYKQDCECRKPKPGMFISARDFLKIDMANSVMIGDKAEDMMAAEAAGVGTKVLVRTGKPITE
KGEALASVVLDSIKDVPAFLKG

Specific function: Converts the D-glycero-beta-D-manno-heptose 1,7- bisphosphate intermediate into D-glycero-beta-D-manno-heptose 1- phosphate by removing the phosphate group at the C-7 position [H]

COG id: COG0241

COG function: function code E; Histidinol phosphatase and related phosphatases

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the gmhB family [H]

Homologues:

Organism=Escherichia coli, GI1786399, Length=181, Percent_Identity=62.9834254143646, Blast_Score=247, Evalue=4e-67,
Organism=Escherichia coli, GI87082027, Length=150, Percent_Identity=31.3333333333333, Blast_Score=72, Evalue=3e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005834
- InterPro:   IPR023214
- InterPro:   IPR006549
- InterPro:   IPR004446
- InterPro:   IPR006543 [H]

Pfam domain/function: PF00702 Hydrolase [H]

EC number: 3.1.1.-

Molecular weight: Translated: 20273; Mature: 20142

Theoretical pI: Translated: 4.68; Mature: 4.68

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
4.9 %Met     (Translated Protein)
6.6 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
4.4 %Met     (Mature Protein)
6.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSKPAVFLDRDGVINVDHGYVHDEHDFEYIDGVFEAAKAFKDMGYLLVLVTNQSGIARGM
CCCCCEEEECCCEEECCCCEEECCCCHHHHHHHHHHHHHHHCCCEEEEEEECCCCCCCCC
FSEDRFLSLTQWMDWNFVDNGVELDGIYYCPHHAEHGVGDYKQDCECRKPKPGMFISARD
CCCCCEEEHHHHCCCCCCCCCEEECEEEECCCCCCCCCCCCCCCCCCCCCCCCEEEECCC
FLKIDMANSVMIGDKAEDMMAAEAAGVGTKVLVRTGKPITEKGEALASVVLDSIKDVPAF
EEEEECCCEEEECCCHHHHHHHHHCCCCEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHH
LKG
HCC
>Mature Secondary Structure 
SKPAVFLDRDGVINVDHGYVHDEHDFEYIDGVFEAAKAFKDMGYLLVLVTNQSGIARGM
CCCCEEEECCCEEECCCCEEECCCCHHHHHHHHHHHHHHHCCCEEEEEEECCCCCCCCC
FSEDRFLSLTQWMDWNFVDNGVELDGIYYCPHHAEHGVGDYKQDCECRKPKPGMFISARD
CCCCCEEEHHHHCCCCCCCCCEEECEEEECCCCCCCCCCCCCCCCCCCCCCCCEEEECCC
FLKIDMANSVMIGDKAEDMMAAEAAGVGTKVLVRTGKPITEKGEALASVVLDSIKDVPAF
EEEEECCCEEEECCCHHHHHHHHHCCCCEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHH
LKG
HCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10952301; 12101286 [H]