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The map label for this gene is treB [H]

Identifier: 218710342

GI number: 218710342

Start: 2546494

End: 2547939

Strand: Reverse

Name: treB [H]

Synonym: VS_2378

Alternate gene names: 218710342

Gene position: 2547939-2546494 (Counterclockwise)

Preceding gene: 218710343

Following gene: 218710341

Centisome position: 77.23

GC content: 48.06

Gene sequence:

>1446_bases
ATGAAACCAGGGTGGGGTAGTATGAGTAAGATAGCGAAGCAAGACGTTGCGCGTCTTATCGAGTTAGTCGGTGGCAAAGA
GAATATTGCGAGTGTCAGCCATTGTCTGACTCGACTGCGTTTTGTATTGAATGATACAGAAAAAGCGAACAAAGCAGAAT
TAGAGAAGCTTAAGCTGGTAAAAGGTTGCTTTACTAACGCAGGTCAATTCCAAGTGGTTATTGGCACCGAGGTTGATGAG
GTGTACGCACTTTTGATTGAGCAAACTGGCAAAGATGCATCATCAAAAGATGAGGCGAAGTTGGCTGCTCGCCAGAACAT
GAACTTCCTTGAGCGTGGTATCTCCCATTTAGCCGAAATTTTCGTACCACTGCTGCCTGCCATTATTACTGGTGGTTTGA
TTCTTGGTTTCCGTAATGTGATTGGCGACATTCGCATGTTCGACGGCAAAACCTTGGTTGAGATCAGCCAATTTTGGGCA
ACCGTTCACTCTTTCTTATGGTTGATTGGCGAAGCGATTTTCTTCTTCCTACCGGTTGGTGTGTGTTGGGCGACGGTTAA
GAAACTCGGCGGAACCCCTATTTTGGGTATCACGCTCGGTGTGACCTTGGTTTCCCCACAATTGATGAACGCTTACATGA
TAGGTAAGTCGGTGCCTGAAGTGTGGGACTTTGGCTTGTTCGTGATTGAGAAAGTCGGTTATCAAGCTCAGGTGATCCCT
GCAATGTTAGCGGGTGTGGCTCTGGCCTTCATCGAGACCAACCTTAAGCGCATTGTTCCTTCTTATCTGTACCTCGTTGT
CGTGCCATTTGTCTCGATCATCTTGTCTGTGATTCTAGCGCACGCTTTCATTGGCCCATTCGGTCGTATGTTAGGTGATG
GTGTGGCATTCGCGGCTAAAGTGGCAATGACTGGTGACTTCGCCATTCTTGGGTCTGTAGTCTTTGGCTTCTTATACGCA
CCTTTGGTTATCACGGGTATTCACCACACAACCAACGCTGTGGACTTACAACTAATGCAAGACTTAGGTGGCACACCAAT
CTGGCCTTTGATTGCGCTATCAAACATTGCACAAGCTTCAGCGGTTGTCGGCATCATCTTTTTGAGTAAGCGCGAAGGCG
AACGAGACATCTCGGTACCTGCGGCAATCTCTGCGTACTTAGGTGTGACGGAACCAGCGATGTACGGCATCAACCTTAAA
TACAAATTCCCAATGCTGAGCGCAATGATCGGCAGTGCCGCAGCGGCTGCAATCTGCGGTAGTGCTGGTGTAATGGCGAA
TGGTATCGGTGTTGGTGGCTTGCCGGGTATCTTATCGATTCAACCTCAATATTGGTCGATTTACTTAGTCGCGATGCTGG
TGGCGGTTGTACTGCCGATAACGCTGACATTGTTCTTCTATAAACGAGCACAGATGAAAGGCGAGCTAGAAACCGCCAAC
GCGTAA

Upstream 100 bases:

>100_bases
ATTTATCATTCACGTGGGCATTATAATAACGGCAATTGGGAATGTTCCCATTAATCTAAATCCGAGTGGCTATCGCTGCA
TGGTTTAGGTGAGTAATTGA

Downstream 100 bases:

>100_bases
TGCATTTAGCAAGCGATGACTTCAAGCAAGTCATCGCTTTTTCCCTTAGTTATAGCTTTTTCTTTTAGTTATAACGGCTA
TTCGACCATGATTCACATGG

Product: PTS system trehalose(maltose)-specific transporter subunits IIBC

Products: NA

Alternate protein names: EIIBC-Tre; EII-Tre; Trehalose-specific phosphotransferase enzyme IIB component; PTS system trehalose-specific EIIB component; Trehalose permease IIC component; PTS system trehalose-specific EIIC component [H]

Number of amino acids: Translated: 481; Mature: 481

Protein sequence:

>481_residues
MKPGWGSMSKIAKQDVARLIELVGGKENIASVSHCLTRLRFVLNDTEKANKAELEKLKLVKGCFTNAGQFQVVIGTEVDE
VYALLIEQTGKDASSKDEAKLAARQNMNFLERGISHLAEIFVPLLPAIITGGLILGFRNVIGDIRMFDGKTLVEISQFWA
TVHSFLWLIGEAIFFFLPVGVCWATVKKLGGTPILGITLGVTLVSPQLMNAYMIGKSVPEVWDFGLFVIEKVGYQAQVIP
AMLAGVALAFIETNLKRIVPSYLYLVVVPFVSIILSVILAHAFIGPFGRMLGDGVAFAAKVAMTGDFAILGSVVFGFLYA
PLVITGIHHTTNAVDLQLMQDLGGTPIWPLIALSNIAQASAVVGIIFLSKREGERDISVPAAISAYLGVTEPAMYGINLK
YKFPMLSAMIGSAAAAAICGSAGVMANGIGVGGLPGILSIQPQYWSIYLVAMLVAVVLPITLTLFFYKRAQMKGELETAN
A

Sequences:

>Translated_481_residues
MKPGWGSMSKIAKQDVARLIELVGGKENIASVSHCLTRLRFVLNDTEKANKAELEKLKLVKGCFTNAGQFQVVIGTEVDE
VYALLIEQTGKDASSKDEAKLAARQNMNFLERGISHLAEIFVPLLPAIITGGLILGFRNVIGDIRMFDGKTLVEISQFWA
TVHSFLWLIGEAIFFFLPVGVCWATVKKLGGTPILGITLGVTLVSPQLMNAYMIGKSVPEVWDFGLFVIEKVGYQAQVIP
AMLAGVALAFIETNLKRIVPSYLYLVVVPFVSIILSVILAHAFIGPFGRMLGDGVAFAAKVAMTGDFAILGSVVFGFLYA
PLVITGIHHTTNAVDLQLMQDLGGTPIWPLIALSNIAQASAVVGIIFLSKREGERDISVPAAISAYLGVTEPAMYGINLK
YKFPMLSAMIGSAAAAAICGSAGVMANGIGVGGLPGILSIQPQYWSIYLVAMLVAVVLPITLTLFFYKRAQMKGELETAN
A
>Mature_481_residues
MKPGWGSMSKIAKQDVARLIELVGGKENIASVSHCLTRLRFVLNDTEKANKAELEKLKLVKGCFTNAGQFQVVIGTEVDE
VYALLIEQTGKDASSKDEAKLAARQNMNFLERGISHLAEIFVPLLPAIITGGLILGFRNVIGDIRMFDGKTLVEISQFWA
TVHSFLWLIGEAIFFFLPVGVCWATVKKLGGTPILGITLGVTLVSPQLMNAYMIGKSVPEVWDFGLFVIEKVGYQAQVIP
AMLAGVALAFIETNLKRIVPSYLYLVVVPFVSIILSVILAHAFIGPFGRMLGDGVAFAAKVAMTGDFAILGSVVFGFLYA
PLVITGIHHTTNAVDLQLMQDLGGTPIWPLIALSNIAQASAVVGIIFLSKREGERDISVPAAISAYLGVTEPAMYGINLK
YKFPMLSAMIGSAAAAAICGSAGVMANGIGVGGLPGILSIQPQYWSIYLVAMLVAVVLPITLTLFFYKRAQMKGELETAN
A

Specific function: The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS), a major carbohydrate active -transport system, catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. This

COG id: COG1263

COG function: function code G; Phosphotransferase system IIC components, glucose/maltose/N-acetylglucosamine-specific

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PTS EIIC type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI2367362, Length=470, Percent_Identity=68.0851063829787, Blast_Score=650, Evalue=0.0,
Organism=Escherichia coli, GI1790159, Length=438, Percent_Identity=27.3972602739726, Blast_Score=147, Evalue=1e-36,
Organism=Escherichia coli, GI48994906, Length=463, Percent_Identity=26.7818574514039, Blast_Score=126, Evalue=3e-30,
Organism=Escherichia coli, GI1788769, Length=423, Percent_Identity=24.822695035461, Blast_Score=112, Evalue=4e-26,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR018113
- InterPro:   IPR004719
- InterPro:   IPR001996
- InterPro:   IPR003352
- InterPro:   IPR013013
- InterPro:   IPR011535
- InterPro:   IPR011296 [H]

Pfam domain/function: PF00367 PTS_EIIB; PF02378 PTS_EIIC [H]

EC number: =2.7.1.69 [H]

Molecular weight: Translated: 51603; Mature: 51603

Theoretical pI: Translated: 8.29; Mature: 8.29

Prosite motif: PS01035 PTS_EIIB_TYPE_1_CYS ; PS51098 PTS_EIIB_TYPE_1 ; PS51103 PTS_EIIC_TYPE_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKPGWGSMSKIAKQDVARLIELVGGKENIASVSHCLTRLRFVLNDTEKANKAELEKLKLV
CCCCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHH
KGCFTNAGQFQVVIGTEVDEVYALLIEQTGKDASSKDEAKLAARQNMNFLERGISHLAEI
HHHCCCCCCEEEEECCCHHHHHHHHHHHCCCCCCCCHHHHHHHHHCHHHHHHHHHHHHHH
FVPLLPAIITGGLILGFRNVIGDIRMFDGKTLVEISQFWATVHSFLWLIGEAIFFFLPVG
HHHHHHHHHHHHHHHHHHHHHCCHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VCWATVKKLGGTPILGITLGVTLVSPQLMNAYMIGKSVPEVWDFGLFVIEKVGYQAQVIP
HHHHHHHHHCCCCEEHHHHHHHHHCHHHHHHHHHCCCCHHHHHHHHHHHHHHCCHHHHHH
AMLAGVALAFIETNLKRIVPSYLYLVVVPFVSIILSVILAHAFIGPFGRMLGDGVAFAAK
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHH
VAMTGDFAILGSVVFGFLYAPLVITGIHHTTNAVDLQLMQDLGGTPIWPLIALSNIAQAS
HHHCCCHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHCCCCCHHHHHHHHHHHHHH
AVVGIIFLSKREGERDISVPAAISAYLGVTEPAMYGINLKYKFPMLSAMIGSAAAAAICG
HHHHHHEEECCCCCCCCCCHHHHHHHHCCCCCHHCCCEEEEECHHHHHHHHHHHHHHHHC
SAGVMANGIGVGGLPGILSIQPQYWSIYLVAMLVAVVLPITLTLFFYKRAQMKGELETAN
CCCHHCCCCCCCCCCCCEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCC
A
C
>Mature Secondary Structure
MKPGWGSMSKIAKQDVARLIELVGGKENIASVSHCLTRLRFVLNDTEKANKAELEKLKLV
CCCCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHH
KGCFTNAGQFQVVIGTEVDEVYALLIEQTGKDASSKDEAKLAARQNMNFLERGISHLAEI
HHHCCCCCCEEEEECCCHHHHHHHHHHHCCCCCCCCHHHHHHHHHCHHHHHHHHHHHHHH
FVPLLPAIITGGLILGFRNVIGDIRMFDGKTLVEISQFWATVHSFLWLIGEAIFFFLPVG
HHHHHHHHHHHHHHHHHHHHHCCHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VCWATVKKLGGTPILGITLGVTLVSPQLMNAYMIGKSVPEVWDFGLFVIEKVGYQAQVIP
HHHHHHHHHCCCCEEHHHHHHHHHCHHHHHHHHHCCCCHHHHHHHHHHHHHHCCHHHHHH
AMLAGVALAFIETNLKRIVPSYLYLVVVPFVSIILSVILAHAFIGPFGRMLGDGVAFAAK
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHH
VAMTGDFAILGSVVFGFLYAPLVITGIHHTTNAVDLQLMQDLGGTPIWPLIALSNIAQAS
HHHCCCHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHCCCCCHHHHHHHHHHHHHH
AVVGIIFLSKREGERDISVPAAISAYLGVTEPAMYGINLKYKFPMLSAMIGSAAAAAICG
HHHHHHEEECCCCCCCCCCHHHHHHHHCCCCCHHCCCEEEEECHHHHHHHHHHHHHHHHC
SAGVMANGIGVGGLPGILSIQPQYWSIYLVAMLVAVVLPITLTLFFYKRAQMKGELETAN
CCCHHCCCCCCCCCCCCEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCC
A
C

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7608078; 7610040; 9278503 [H]