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The map label for this gene is accA

Identifier: 218710302

GI number: 218710302

Start: 2502911

End: 2503870

Strand: Reverse

Name: accA

Synonym: VS_2336

Alternate gene names: 218710302

Gene position: 2503870-2502911 (Counterclockwise)

Preceding gene: 218710303

Following gene: 218710301

Centisome position: 75.89

GC content: 47.4

Gene sequence:

>960_bases
ATGAGCCTGAACTTTCTAGAATTTGAAAAGCCTATCGCTGAACTTGAAGCAAAAATCGAAGCGCTACGTGACGTTTCGCG
TCACGGTGGTGACACAGCGGTAGATCTAGACAAAGAAATTGAACAACTAGAGAAAAAAAGCTTAGAGCTTAAACAGAAAA
TCTTTAGTGACTTAGGTGCATGGCAGGTAGCTCAACTTGCTCGTCACCCTCAACGTCCTTACACCAAAGATTACCTGGAG
CATGCCTTCACAGAGTTTGAAGAGATGGCGGGCGATCGCGCTTACGCTGACGACAAAGCAATTGTGGGTGGTATGGCTCG
TCTAAATGGTCGCCCTGTTATGGTTATTGGTCACCAGAAAGGTCGTGAGACTAAAGAGAAAGTGATCCGTAACTTTGGTA
TGCCAAAGCCAGAAGGTTACCGTAAGGCACTTCGCCTAATGGAAACGGCTGAGCGTTTCAACATGCCAATCATTACTTTC
ATCGACACAGCGGGTGCTTACCCAGGTGTTGGTGCTGAAGAACGTGGCCAATCTGAAGCGATCGCAAAGAACCTTAAAGT
AATGGCTGGTCTTTCAGTTCCAGTTATCTGTAACGTTGTTGGTGAAGGCGGTTCTGGTGGTGCACTAGCGATTGGTGTTG
GCGACTACGTGAACATGCTTCAGTACTCTACGTACTCAGTAATCTCTCCAGAAGGTTGTGCTTCAATCCTGTGGCGTGAT
TCAGATAAAGCGCCACAAGCTGCTGAAGCGATGGGCCTAGTTGCTCCTCGCCTGAAAGAGCTAGAGCTTATCGACGAAAT
CATTCCTGAGCCTCTAGGTGGCGCGCACCGCGATCCAATACAGACAGCTCAGAACATGAAAGACATGTTAGTTAAGCAGT
TAGAAGAGCTAGAGCAATTTGATAACGAAGCACTTCTAGAGCGTCGTTACCAGCGTCTAATGAGCTACGGTTACTGCTGA

Upstream 100 bases:

>100_bases
AGACGAATTAAAACAGCTGCTTGGAAATAGCCAAGTAGAACTCGAATTTAACTAAAATTTAGCTCCGTAACTGCGGAGCT
GAATCAACAAGGATTCATAG

Downstream 100 bases:

>100_bases
TAAGCGACCTTAGCAAGGTGTAAGACCTGCTTTCCGTAACAAGTTGATGAAAGGGTTGGACTCAGTGCCAACCCTTTTTT
ATTATTAAAACATTCTCCTT

Product: acetyl-CoA carboxylase carboxyltransferase subunit alpha

Products: NA

Alternate protein names: ACCase subunit alpha; Acetyl-CoA carboxylase carboxyltransferase subunit alpha

Number of amino acids: Translated: 319; Mature: 318

Protein sequence:

>319_residues
MSLNFLEFEKPIAELEAKIEALRDVSRHGGDTAVDLDKEIEQLEKKSLELKQKIFSDLGAWQVAQLARHPQRPYTKDYLE
HAFTEFEEMAGDRAYADDKAIVGGMARLNGRPVMVIGHQKGRETKEKVIRNFGMPKPEGYRKALRLMETAERFNMPIITF
IDTAGAYPGVGAEERGQSEAIAKNLKVMAGLSVPVICNVVGEGGSGGALAIGVGDYVNMLQYSTYSVISPEGCASILWRD
SDKAPQAAEAMGLVAPRLKELELIDEIIPEPLGGAHRDPIQTAQNMKDMLVKQLEELEQFDNEALLERRYQRLMSYGYC

Sequences:

>Translated_319_residues
MSLNFLEFEKPIAELEAKIEALRDVSRHGGDTAVDLDKEIEQLEKKSLELKQKIFSDLGAWQVAQLARHPQRPYTKDYLE
HAFTEFEEMAGDRAYADDKAIVGGMARLNGRPVMVIGHQKGRETKEKVIRNFGMPKPEGYRKALRLMETAERFNMPIITF
IDTAGAYPGVGAEERGQSEAIAKNLKVMAGLSVPVICNVVGEGGSGGALAIGVGDYVNMLQYSTYSVISPEGCASILWRD
SDKAPQAAEAMGLVAPRLKELELIDEIIPEPLGGAHRDPIQTAQNMKDMLVKQLEELEQFDNEALLERRYQRLMSYGYC
>Mature_318_residues
SLNFLEFEKPIAELEAKIEALRDVSRHGGDTAVDLDKEIEQLEKKSLELKQKIFSDLGAWQVAQLARHPQRPYTKDYLEH
AFTEFEEMAGDRAYADDKAIVGGMARLNGRPVMVIGHQKGRETKEKVIRNFGMPKPEGYRKALRLMETAERFNMPIITFI
DTAGAYPGVGAEERGQSEAIAKNLKVMAGLSVPVICNVVGEGGSGGALAIGVGDYVNMLQYSTYSVISPEGCASILWRDS
DKAPQAAEAMGLVAPRLKELELIDEIIPEPLGGAHRDPIQTAQNMKDMLVKQLEELEQFDNEALLERRYQRLMSYGYC

Specific function: Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-Co

COG id: COG0825

COG function: function code I; Acetyl-CoA carboxylase alpha subunit

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the AccA family

Homologues:

Organism=Escherichia coli, GI1786382, Length=319, Percent_Identity=73.6677115987461, Blast_Score=495, Evalue=1e-141,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): ACCA_VIBSL (B7VIQ2)

Other databases:

- EMBL:   FM954972
- RefSeq:   YP_002417923.1
- ProteinModelPortal:   B7VIQ2
- SMR:   B7VIQ2
- GeneID:   7161877
- GenomeReviews:   FM954972_GR
- KEGG:   vsp:VS_2336
- HOGENOM:   HBG286557
- OMA:   QLTKDIY
- ProtClustDB:   PRK05724
- HAMAP:   MF_00823
- InterPro:   IPR001095
- InterPro:   IPR011763
- PANTHER:   PTHR22855:SF3
- PRINTS:   PR01069
- TIGRFAMs:   TIGR00513

Pfam domain/function: PF03255 ACCA

EC number: =6.4.1.2

Molecular weight: Translated: 35480; Mature: 35349

Theoretical pI: Translated: 4.90; Mature: 4.90

Prosite motif: PS50989 COA_CT_CTER

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
4.1 %Met     (Translated Protein)
5.0 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
3.8 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSLNFLEFEKPIAELEAKIEALRDVSRHGGDTAVDLDKEIEQLEKKSLELKQKIFSDLGA
CCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHCH
WQVAQLARHPQRPYTKDYLEHAFTEFEEMAGDRAYADDKAIVGGMARLNGRPVMVIGHQK
HHHHHHHHCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHCCCCEEEEEECCC
GRETKEKVIRNFGMPKPEGYRKALRLMETAERFNMPIITFIDTAGAYPGVGAEERGQSEA
CCHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHCCCEEEEEECCCCCCCCCCHHCCHHHH
IAKNLKVMAGLSVPVICNVVGEGGSGGALAIGVGDYVNMLQYSTYSVISPEGCASILWRD
HHHHHHHHHCCCHHHHEEEECCCCCCCEEEEEHHHHHHHHHHHHHCCCCCCHHHHHHCCC
SDKAPQAAEAMGLVAPRLKELELIDEIIPEPLGGAHRDPIQTAQNMKDMLVKQLEELEQF
CCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHH
DNEALLERRYQRLMSYGYC
CHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure 
SLNFLEFEKPIAELEAKIEALRDVSRHGGDTAVDLDKEIEQLEKKSLELKQKIFSDLGA
CCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHCH
WQVAQLARHPQRPYTKDYLEHAFTEFEEMAGDRAYADDKAIVGGMARLNGRPVMVIGHQK
HHHHHHHHCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHCCCCEEEEEECCC
GRETKEKVIRNFGMPKPEGYRKALRLMETAERFNMPIITFIDTAGAYPGVGAEERGQSEA
CCHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHCCCEEEEEECCCCCCCCCCHHCCHHHH
IAKNLKVMAGLSVPVICNVVGEGGSGGALAIGVGDYVNMLQYSTYSVISPEGCASILWRD
HHHHHHHHHCCCHHHHEEEECCCCCCCEEEEEHHHHHHHHHHHHHCCCCCCHHHHHHCCC
SDKAPQAAEAMGLVAPRLKELELIDEIIPEPLGGAHRDPIQTAQNMKDMLVKQLEELEQF
CCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHH
DNEALLERRYQRLMSYGYC
CHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA