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The map label for this gene is insF7 [C]

Identifier: 218710292

GI number: 218710292

Start: 2494329

End: 2495135

Strand: Reverse

Name: insF7 [C]

Synonym: VS_2326

Alternate gene names: 218710292

Gene position: 2495135-2494329 (Counterclockwise)

Preceding gene: 218710293

Following gene: 218710290

Centisome position: 75.63

GC content: 42.75

Gene sequence:

>807_bases
TTGACCGTCACCAAAGCTTGTCACTTCATAGGTATTACACGACAAGCTTTCTACAAGCGCTGTGTTGCAGAAATTCATCA
GACAAAGAAAGATGAATCTGTGCTCGGTTTTGTGAAGGAGCAAAGGATGATGCACCCTCGAATAGGGGCTCGTAAGATCA
AGTATTTACTTGCTCAGAACGATATTGAAATCGGGCGAGACCGCTTATTCTCTCTGCTGAGAGTGAATCGATTATTAGTA
CAGAATCGAAGGGCTTACCATCGAACCACAAACAGTAATCATCGCTTTTACTGCCATCCAAATCGAATCAAAGAAGGCTT
AATACCGGAAGGACCGGAGCAATTATGGGTTGCCGATATTACTTATCTAGCAACGCGGCGTGGTAGTACTTATCTCAGTT
TAGTGACGGACGCTTACTCAAGAAAAATCGTGGGCTATCACATAAGTGATGATATGAAAGCTCACACGGTCAAGCAGGCC
TTTTTAAACGCGCTGAAAGGGCGGAAGAATACAGGTGAGCTTGTCCATCACTCAGATAGAGGTGTTCAGTACTGCTCTGT
TGAATACCAAGAGTTGCATCGACAGTATGGTGTATCTTGCTCAATGACTGATGGCTATGACTGTTATCAGAATGCGTTGG
CAGAGAGGGTCAACGGAATATTGAAGATGGAGTATCTGTTGAATAAGCCTAATGATTTAGATGAAGCAAAGAAAATGGTC
GCTGAATCAGTAAAAATCTATAATGAATATAGGCCTCACACAGCTCTAAAATACAAAACGCCCGATGAAGTACATCGAGC
GTTTTAG

Upstream 100 bases:

>100_bases
AGTTCTTTGAAGCGGTTGTAAAAGTCATGGATCGAGATTTCGGAGTCCGAATCTCAAAGAAGCGCAGGGCCGAGTTATTA
AGGAAAAAGCGGTCAGAAAG

Downstream 100 bases:

>100_bases
TCAATCAAGTGTCAACCCATATCAGGACGGGTCAATATCTGTTTTAGATACTGACATTTCCTTTAAGAAAATGATCAGCT
TGGCTGATAGCCCGTATCTT

Product: ISVisp4 transposase OrfB

Products: NA

Alternate protein names: ISO-S3 31 kDa protein [H]

Number of amino acids: Translated: 268; Mature: 267

Protein sequence:

>268_residues
MTVTKACHFIGITRQAFYKRCVAEIHQTKKDESVLGFVKEQRMMHPRIGARKIKYLLAQNDIEIGRDRLFSLLRVNRLLV
QNRRAYHRTTNSNHRFYCHPNRIKEGLIPEGPEQLWVADITYLATRRGSTYLSLVTDAYSRKIVGYHISDDMKAHTVKQA
FLNALKGRKNTGELVHHSDRGVQYCSVEYQELHRQYGVSCSMTDGYDCYQNALAERVNGILKMEYLLNKPNDLDEAKKMV
AESVKIYNEYRPHTALKYKTPDEVHRAF

Sequences:

>Translated_268_residues
MTVTKACHFIGITRQAFYKRCVAEIHQTKKDESVLGFVKEQRMMHPRIGARKIKYLLAQNDIEIGRDRLFSLLRVNRLLV
QNRRAYHRTTNSNHRFYCHPNRIKEGLIPEGPEQLWVADITYLATRRGSTYLSLVTDAYSRKIVGYHISDDMKAHTVKQA
FLNALKGRKNTGELVHHSDRGVQYCSVEYQELHRQYGVSCSMTDGYDCYQNALAERVNGILKMEYLLNKPNDLDEAKKMV
AESVKIYNEYRPHTALKYKTPDEVHRAF
>Mature_267_residues
TVTKACHFIGITRQAFYKRCVAEIHQTKKDESVLGFVKEQRMMHPRIGARKIKYLLAQNDIEIGRDRLFSLLRVNRLLVQ
NRRAYHRTTNSNHRFYCHPNRIKEGLIPEGPEQLWVADITYLATRRGSTYLSLVTDAYSRKIVGYHISDDMKAHTVKQAF
LNALKGRKNTGELVHHSDRGVQYCSVEYQELHRQYGVSCSMTDGYDCYQNALAERVNGILKMEYLLNKPNDLDEAKKMVA
ESVKIYNEYRPHTALKYKTPDEVHRAF

Specific function: Involved in the transposition of the insertion sequence is3 [C]

COG id: COG2801

COG function: function code L; Transposase and inactivated derivatives

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 integrase catalytic domain [H]

Homologues:

Organism=Homo sapiens, GI310129419, Length=236, Percent_Identity=30.5084745762712, Blast_Score=98, Evalue=9e-21,
Organism=Escherichia coli, GI1788405, Length=273, Percent_Identity=26.3736263736264, Blast_Score=95, Evalue=4e-21,
Organism=Escherichia coli, GI1787263, Length=273, Percent_Identity=26.3736263736264, Blast_Score=95, Evalue=4e-21,
Organism=Escherichia coli, GI1786753, Length=273, Percent_Identity=26.3736263736264, Blast_Score=95, Evalue=4e-21,
Organism=Escherichia coli, GI1786570, Length=273, Percent_Identity=26.3736263736264, Blast_Score=95, Evalue=4e-21,
Organism=Escherichia coli, GI1786490, Length=273, Percent_Identity=26.3736263736264, Blast_Score=95, Evalue=4e-21,
Organism=Escherichia coli, GI1789981, Length=165, Percent_Identity=30.9090909090909, Blast_Score=82, Evalue=5e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001584
- InterPro:   IPR012337 [H]

Pfam domain/function: PF00665 rve [H]

EC number: NA

Molecular weight: Translated: 31230; Mature: 31099

Theoretical pI: Translated: 9.79; Mature: 9.79

Prosite motif: PS50994 INTEGRASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.2 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
4.9 %Cys+Met (Translated Protein)
2.2 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTVTKACHFIGITRQAFYKRCVAEIHQTKKDESVLGFVKEQRMMHPRIGARKIKYLLAQN
CCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCCHHHHHHHHHCC
DIEIGRDRLFSLLRVNRLLVQNRRAYHRTTNSNHRFYCHPNRIKEGLIPEGPEQLWVADI
CHHHHHHHHHHHHHHHHHHHHCCHHHHCCCCCCCEEEECHHHHHCCCCCCCCHHHHHHHH
TYLATRRGSTYLSLVTDAYSRKIVGYHISDDMKAHTVKQAFLNALKGRKNTGELVHHSDR
HHHHHCCCCHHHHHHHHHHHCCEEEEECCCCHHHHHHHHHHHHHHCCCCCCCHHHCCCCC
GVQYCSVEYQELHRQYGVSCSMTDGYDCYQNALAERVNGILKMEYLLNKPNDLDEAKKMV
CCEEEEHHHHHHHHHHCCEECCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHH
AESVKIYNEYRPHTALKYKTPDEVHRAF
HHHHHHHHHCCCCCEEEECCHHHHHHCC
>Mature Secondary Structure 
TVTKACHFIGITRQAFYKRCVAEIHQTKKDESVLGFVKEQRMMHPRIGARKIKYLLAQN
CHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCCHHHHHHHHHCC
DIEIGRDRLFSLLRVNRLLVQNRRAYHRTTNSNHRFYCHPNRIKEGLIPEGPEQLWVADI
CHHHHHHHHHHHHHHHHHHHHCCHHHHCCCCCCCEEEECHHHHHCCCCCCCCHHHHHHHH
TYLATRRGSTYLSLVTDAYSRKIVGYHISDDMKAHTVKQAFLNALKGRKNTGELVHHSDR
HHHHHCCCCHHHHHHHHHHHCCEEEEECCCCHHHHHHHHHHHHHHCCCCCCCHHHCCCCC
GVQYCSVEYQELHRQYGVSCSMTDGYDCYQNALAERVNGILKMEYLLNKPNDLDEAKKMV
CCEEEEHHHHHHHHHHCCEECCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHH
AESVKIYNEYRPHTALKYKTPDEVHRAF
HHHHHHHHHCCCCCEEEECCHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 2824781 [H]