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The map label for this gene is sglT [H]

Identifier: 218709250

GI number: 218709250

Start: 1353901

End: 1355673

Strand: Direct

Name: sglT [H]

Synonym: VS_1257

Alternate gene names: 218709250

Gene position: 1353901-1355673 (Clockwise)

Preceding gene: 218709249

Following gene: 218709253

Centisome position: 41.04

GC content: 47.32

Gene sequence:

>1773_bases
ATGGAACTCAATACCCTGATAGTTGGCATCTACTTCCTATTCTTAATTGCGATAGGGTGGATGTTCCGAACGTTTACAAG
TACGACAAGTGATTACTTCCGTGGGGGAGGTAATATGCTGTGGTGGATGGTAGGTGCAACCGCATTTATGACCCAGTTCA
GTGCTTGGACATTTACTGGTGCAGCAGGTAAAGCTTTTACCGATGGTTTTGCCGTAGCGATTATCTTCATCGCGAACGCA
TTCGGTTACCTAATGAACTACCTTTACTTCGCTCCGAAGTTCCGCCAACTGCGCGTTGTGACGGTAATTGAAGCGATTCG
TATGCGTTTTGGTAAGGTGAATGAGCAAGTATTTACTTGGTCTGGCATGCCAAACAGCGTTATCTCTGCTGGTATCTGGT
TGAACGGCCTTGCGATCATCGCATCGGGTATCTTCGGCTTTGATATGACAACGACGATTGTCCTAACGGGTCTGGTTGTA
CTGGTAATGTCAGTAACAGGCGGCTCTTGGGCGGTAATCGCATCTGACTTTATGCAGATGGTTATCATCATGGCGGTAAC
GGTGACGTGTGCTGTGGTTGCGATTTACCACGGTGGCGGCGTTACGCAGATCGTTAACGACTTCCCAACAGGTTCATTCA
TTACGGGTGATAACCTGAACTACATGAGCATCTTCAGCATCTGGGCTGTGTTCATCTTCTTAAAGCAGTTCAGCATCACC
AACAACATGCTTAACTCTTACCGTTACCTTGCTGCGAAAGACTCAAACAACGCACGTAAAGCTGCACTGCTTGCTTGTGT
ACTAATGACGCTTGGTCCAATCATCTGGTTCATGCCTTCTTGGTTCATGGCAGGTCAAGGTGTTGATTTAGCAGCAGCTT
ACCCAGACGCTGGCAGCAAAGCCGCTGACTTCGCTTACCTTTACTTTGTTCAAGAATACATGCCTGCAGGTATGGTTGGC
CTTCTGATTGCCGCTATGTTTGCTGCGACTATGTCTTCAATGGACTCTGGTCTAAACCGTAACTCAGGTATCTTTGTTAA
GAACTTCTACGAGCCGATTCTTCGTCCTAAAGCGACAGAGAAAGAGCTAATGGTTGTTTCTAAGCTAACGTCTACTTTCT
TCGGTATCGCGATCATCTTGGTTGCTCTGTTCATCAACTCTCTTAAAGGTCTGAGCCTTTTCGACACCATGATGTACGTG
GGCGCATTGATCGGCTTCCCTATGACAATTCCAGCATTCTGTGGCTTCTTCATCCGTAAAACACCGGATTGGGCAGGTTG
GGGTACGCTAGTAGTCGGTGGTGTGGTTTCTTACTTCGTTGGTTTCGTTATCACAGCGGACATGATTCAAAACTGGTTCG
GTCTAAACGAACTAACTGGCCGTGAGTGGGCTGACCTGAAAGTGGCTATCGGCCTTATCGGTCACATCGTATTTACTGCT
GGCTTCTTCGTTCTTTCAACACTGTTCTACAAGCCATTACCGGAACACCGTGAGAAAGACGTCGACAAGTTCTTCAATAA
CCTAGCGACACCGTTAGTTGCTGAGAGTAATGAACAGAAGAAACTGGATAACAAGCAACGTCGTATGTTGGGGTCACTTA
TCGCGGTAGCGGGTGTGGGCGTAATGACTATGTTTGTACTGCCAAACCCAATGTGGGGACGCATGGTATTCGTTCTGTGT
GGTTTGATTGTGTTCTCTGTCGGCCTGTTACTTGTTAAAGCGGTCGATGACAAAGTCGAGCAACAAGACGAAGTGACGCC
AGCCGAAGGCTAA

Upstream 100 bases:

>100_bases
GTAAGATCACTGTCACGCATTTAAGTTATTGTAGTACAAATATAGTTACCATCTATCTATAGTGACCTTAACAAAAAAAC
ATGAATAAAAAGGTCTCAAG

Downstream 100 bases:

>100_bases
TTCCTTTTAAATCAAAAACTATAACTTTTTACAGCGGCTACCGATTGCGGTAGCCGTTCGTTTGAACTGCCAAAGTTTAA
TGTGATATGTACGGAGAGCT

Product: putative sodium/glucose cotransporter

Products: NA

Alternate protein names: Na(+)/glucose symporter [H]

Number of amino acids: Translated: 590; Mature: 590

Protein sequence:

>590_residues
MELNTLIVGIYFLFLIAIGWMFRTFTSTTSDYFRGGGNMLWWMVGATAFMTQFSAWTFTGAAGKAFTDGFAVAIIFIANA
FGYLMNYLYFAPKFRQLRVVTVIEAIRMRFGKVNEQVFTWSGMPNSVISAGIWLNGLAIIASGIFGFDMTTTIVLTGLVV
LVMSVTGGSWAVIASDFMQMVIIMAVTVTCAVVAIYHGGGVTQIVNDFPTGSFITGDNLNYMSIFSIWAVFIFLKQFSIT
NNMLNSYRYLAAKDSNNARKAALLACVLMTLGPIIWFMPSWFMAGQGVDLAAAYPDAGSKAADFAYLYFVQEYMPAGMVG
LLIAAMFAATMSSMDSGLNRNSGIFVKNFYEPILRPKATEKELMVVSKLTSTFFGIAIILVALFINSLKGLSLFDTMMYV
GALIGFPMTIPAFCGFFIRKTPDWAGWGTLVVGGVVSYFVGFVITADMIQNWFGLNELTGREWADLKVAIGLIGHIVFTA
GFFVLSTLFYKPLPEHREKDVDKFFNNLATPLVAESNEQKKLDNKQRRMLGSLIAVAGVGVMTMFVLPNPMWGRMVFVLC
GLIVFSVGLLLVKAVDDKVEQQDEVTPAEG

Sequences:

>Translated_590_residues
MELNTLIVGIYFLFLIAIGWMFRTFTSTTSDYFRGGGNMLWWMVGATAFMTQFSAWTFTGAAGKAFTDGFAVAIIFIANA
FGYLMNYLYFAPKFRQLRVVTVIEAIRMRFGKVNEQVFTWSGMPNSVISAGIWLNGLAIIASGIFGFDMTTTIVLTGLVV
LVMSVTGGSWAVIASDFMQMVIIMAVTVTCAVVAIYHGGGVTQIVNDFPTGSFITGDNLNYMSIFSIWAVFIFLKQFSIT
NNMLNSYRYLAAKDSNNARKAALLACVLMTLGPIIWFMPSWFMAGQGVDLAAAYPDAGSKAADFAYLYFVQEYMPAGMVG
LLIAAMFAATMSSMDSGLNRNSGIFVKNFYEPILRPKATEKELMVVSKLTSTFFGIAIILVALFINSLKGLSLFDTMMYV
GALIGFPMTIPAFCGFFIRKTPDWAGWGTLVVGGVVSYFVGFVITADMIQNWFGLNELTGREWADLKVAIGLIGHIVFTA
GFFVLSTLFYKPLPEHREKDVDKFFNNLATPLVAESNEQKKLDNKQRRMLGSLIAVAGVGVMTMFVLPNPMWGRMVFVLC
GLIVFSVGLLLVKAVDDKVEQQDEVTPAEG
>Mature_590_residues
MELNTLIVGIYFLFLIAIGWMFRTFTSTTSDYFRGGGNMLWWMVGATAFMTQFSAWTFTGAAGKAFTDGFAVAIIFIANA
FGYLMNYLYFAPKFRQLRVVTVIEAIRMRFGKVNEQVFTWSGMPNSVISAGIWLNGLAIIASGIFGFDMTTTIVLTGLVV
LVMSVTGGSWAVIASDFMQMVIIMAVTVTCAVVAIYHGGGVTQIVNDFPTGSFITGDNLNYMSIFSIWAVFIFLKQFSIT
NNMLNSYRYLAAKDSNNARKAALLACVLMTLGPIIWFMPSWFMAGQGVDLAAAYPDAGSKAADFAYLYFVQEYMPAGMVG
LLIAAMFAATMSSMDSGLNRNSGIFVKNFYEPILRPKATEKELMVVSKLTSTFFGIAIILVALFINSLKGLSLFDTMMYV
GALIGFPMTIPAFCGFFIRKTPDWAGWGTLVVGGVVSYFVGFVITADMIQNWFGLNELTGREWADLKVAIGLIGHIVFTA
GFFVLSTLFYKPLPEHREKDVDKFFNNLATPLVAESNEQKKLDNKQRRMLGSLIAVAGVGVMTMFVLPNPMWGRMVFVLC
GLIVFSVGLLLVKAVDDKVEQQDEVTPAEG

Specific function: Actively transports glucose into cells by Na(+) cotransport [H]

COG id: COG0591

COG function: function code ER; Na+/proline symporter

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family [H]

Homologues:

Organism=Homo sapiens, GI17941285, Length=461, Percent_Identity=27.765726681128, Blast_Score=116, Evalue=6e-26,
Organism=Homo sapiens, GI4507031, Length=454, Percent_Identity=26.8722466960352, Blast_Score=107, Evalue=2e-23,
Organism=Homo sapiens, GI14140236, Length=472, Percent_Identity=26.4830508474576, Blast_Score=102, Evalue=1e-21,
Organism=Homo sapiens, GI4507033, Length=464, Percent_Identity=24.1379310344828, Blast_Score=100, Evalue=4e-21,
Organism=Homo sapiens, GI110835708, Length=413, Percent_Identity=26.8765133171913, Blast_Score=100, Evalue=6e-21,
Organism=Homo sapiens, GI109659836, Length=468, Percent_Identity=25, Blast_Score=95, Evalue=2e-19,
Organism=Homo sapiens, GI109659839, Length=482, Percent_Identity=24.0663900414938, Blast_Score=89, Evalue=9e-18,
Organism=Homo sapiens, GI206597483, Length=596, Percent_Identity=24.6644295302013, Blast_Score=82, Evalue=2e-15,
Organism=Homo sapiens, GI157671931, Length=398, Percent_Identity=22.6130653266332, Blast_Score=78, Evalue=3e-14,
Organism=Homo sapiens, GI4507035, Length=399, Percent_Identity=22.5563909774436, Blast_Score=77, Evalue=3e-14,
Organism=Homo sapiens, GI167466278, Length=398, Percent_Identity=24.3718592964824, Blast_Score=77, Evalue=4e-14,
Organism=Homo sapiens, GI206597487, Length=528, Percent_Identity=24.6212121212121, Blast_Score=74, Evalue=3e-13,
Organism=Homo sapiens, GI310128183, Length=405, Percent_Identity=22.2222222222222, Blast_Score=73, Evalue=8e-13,
Organism=Escherichia coli, GI1790113, Length=450, Percent_Identity=23.7777777777778, Blast_Score=91, Evalue=2e-19,
Organism=Caenorhabditis elegans, GI17539284, Length=465, Percent_Identity=23.8709677419355, Blast_Score=90, Evalue=3e-18,
Organism=Drosophila melanogaster, GI221459586, Length=401, Percent_Identity=22.1945137157107, Blast_Score=75, Evalue=2e-13,
Organism=Drosophila melanogaster, GI24651739, Length=362, Percent_Identity=23.2044198895028, Blast_Score=70, Evalue=4e-12,
Organism=Drosophila melanogaster, GI221379702, Length=338, Percent_Identity=24.2603550295858, Blast_Score=69, Evalue=1e-11,
Organism=Drosophila melanogaster, GI221459588, Length=373, Percent_Identity=22.7882037533512, Blast_Score=66, Evalue=5e-11,
Organism=Drosophila melanogaster, GI221459584, Length=356, Percent_Identity=21.6292134831461, Blast_Score=66, Evalue=8e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001734
- InterPro:   IPR018212
- InterPro:   IPR019900 [H]

Pfam domain/function: PF00474 SSF [H]

EC number: NA

Molecular weight: Translated: 64891; Mature: 64891

Theoretical pI: Translated: 7.91; Mature: 7.91

Prosite motif: PS50283 NA_SOLUT_SYMP_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
5.6 %Met     (Translated Protein)
6.3 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
5.6 %Met     (Mature Protein)
6.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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HHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCC
>Mature Secondary Structure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HHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8652595; 10835424; 10757971 [H]