Click here to switch to the map view.

The map label for this gene is infC [H]

Identifier: 218709222

GI number: 218709222

Start: 1305971

End: 1306441

Strand: Direct

Name: infC [H]

Synonym: VS_1229

Alternate gene names: 218709222

Gene position: 1305971-1306441 (Clockwise)

Preceding gene: 218709221

Following gene: 218709223

Centisome position: 39.58

GC content: 46.28

Gene sequence:

>471_bases
GTGCGTCTAACTGGCGCAGACGGCGAAGCTGTTGGTGTAGTAACAATCGCTGAAGCGATGGAAGCTGCAAATGAAGCTGG
TATGGATCTTGTAGAGATCAGCCCTAACGCCGAGCCGCCAGTTTGTCGTGTGATGGACTACGGTAAGTTCCTCTTCGAGA
AGAGCAAAGCTGCGAAAGAGCAGAAGAAAAAGCAAAAGCAGGTTCAGATCAAGGAAATTAAATTCCGACCTGGAACTGAT
ATTGGAGACTATCAGGTAAAACTACGCAACCTGACTGGTTTCCTTGAAGACGGCAACAAAGTGAAGGTAACAATTCGCTT
CCGTGGCCGCGAAATGGCTCACCAAGAAATCGGTGTTGACGTTCTTAATCGTTTGAAAGTAGATACTGAAGAATTTGCAG
TTGTCGAATCTTTCCCAACGAGAATTGAAGGTCGCCAGATGATCATGGTGTTGGCCCCTAAAAAGAAGTAA

Upstream 100 bases:

>100_bases
TCAATCTGGAGGAATAGCTATTAAAGGCGGAAGACGTGGCCAACAACCGGCCAAACAAAACCAGCACCGTTTAAACGGTG
ACATTCGTGGCGTTCGTGAA

Downstream 100 bases:

>100_bases
TTAACGGCTTTGCAAGTAATTAAACCCTGCAGCCTCAGGTTGCGGGGTTTTATTCGCCCTAATTACTATGTTATTAACAA
CTCAACAATGCGGAGTTATT

Product: translation initiation factor IF-3

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 156; Mature: 156

Protein sequence:

>156_residues
MRLTGADGEAVGVVTIAEAMEAANEAGMDLVEISPNAEPPVCRVMDYGKFLFEKSKAAKEQKKKQKQVQIKEIKFRPGTD
IGDYQVKLRNLTGFLEDGNKVKVTIRFRGREMAHQEIGVDVLNRLKVDTEEFAVVESFPTRIEGRQMIMVLAPKKK

Sequences:

>Translated_156_residues
MRLTGADGEAVGVVTIAEAMEAANEAGMDLVEISPNAEPPVCRVMDYGKFLFEKSKAAKEQKKKQKQVQIKEIKFRPGTD
IGDYQVKLRNLTGFLEDGNKVKVTIRFRGREMAHQEIGVDVLNRLKVDTEEFAVVESFPTRIEGRQMIMVLAPKKK
>Mature_156_residues
MRLTGADGEAVGVVTIAEAMEAANEAGMDLVEISPNAEPPVCRVMDYGKFLFEKSKAAKEQKKKQKQVQIKEIKFRPGTD
IGDYQVKLRNLTGFLEDGNKVKVTIRFRGREMAHQEIGVDVLNRLKVDTEEFAVVESFPTRIEGRQMIMVLAPKKK

Specific function: IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins [H]

COG id: COG0290

COG function: function code J; Translation initiation factor 3 (IF-3)

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the IF-3 family [H]

Homologues:

Organism=Escherichia coli, GI1788012, Length=156, Percent_Identity=75.6410256410256, Blast_Score=227, Evalue=3e-61,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR019813
- InterPro:   IPR001288
- InterPro:   IPR019815
- InterPro:   IPR019814 [H]

Pfam domain/function: PF00707 IF3_C; PF05198 IF3_N [H]

EC number: NA

Molecular weight: Translated: 17512; Mature: 17512

Theoretical pI: Translated: 9.49; Mature: 9.49

Prosite motif: PS00938 IF3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
4.5 %Met     (Translated Protein)
5.1 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
4.5 %Met     (Mature Protein)
5.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRLTGADGEAVGVVTIAEAMEAANEAGMDLVEISPNAEPPVCRVMDYGKFLFEKSKAAKE
CCCCCCCCCEEEEEEHHHHHHHHHHCCCEEEEECCCCCCCEEHHHHHHHHHHHHHHHHHH
QKKKQKQVQIKEIKFRPGTDIGDYQVKLRNLTGFLEDGNKVKVTIRFRGREMAHQEIGVD
HHHHHHCCEEEEEEECCCCCCCCEEEEEEEEEEEECCCCEEEEEEEECCCHHHHHHHCHH
VLNRLKVDTEEFAVVESFPTRIEGRQMIMVLAPKKK
HHHHHCCCHHHHHHHHHCCCCCCCCEEEEEEECCCC
>Mature Secondary Structure
MRLTGADGEAVGVVTIAEAMEAANEAGMDLVEISPNAEPPVCRVMDYGKFLFEKSKAAKE
CCCCCCCCCEEEEEEHHHHHHHHHHCCCEEEEECCCCCCCEEHHHHHHHHHHHHHHHHHH
QKKKQKQVQIKEIKFRPGTDIGDYQVKLRNLTGFLEDGNKVKVTIRFRGREMAHQEIGVD
HHHHHHCCEEEEEEECCCCCCCCEEEEEEEEEEEECCCCEEEEEEEECCCHHHHHHHCHH
VLNRLKVDTEEFAVVESFPTRIEGRQMIMVLAPKKK
HHHHHCCCHHHHHHHHHCCCCCCCCEEEEEEECCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9554855; 10952301 [H]