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The map label for this gene is proX [H]

Identifier: 218709174

GI number: 218709174

Start: 1249163

End: 1250170

Strand: Direct

Name: proX [H]

Synonym: VS_1181

Alternate gene names: 218709174

Gene position: 1249163-1250170 (Clockwise)

Preceding gene: 218709173

Following gene: 218709176

Centisome position: 37.86

GC content: 44.05

Gene sequence:

>1008_bases
ATGAATAATTCATGGAAGAGTAAGCTAGCCGTTAGCATCGTTTCGACACTGGCTGTATCAACGAACGTGTGGGCTGCAAG
CTTACCGGGTGAAGGTGTATCAGTTCAGCCCGTTCAATCTTCAGTTGCTGAAGAAACGTTCCAAACACTGATTGTTAACC
GTGCTTTAGAAGAGCTTGGTTACGATGTGAAATCAACGCAAGAAGTGGACTACAACGTAGCTTACACTTCTATCGCAAAA
GGTGACGCAACGTTCCTAACAGTAGGTTGGTTCCCACTACACGCTGACAAATACAAAATGGCGGGTGGCGATGACAAATT
CTACCGTGAAGGCCAATATGTAAGTGGTGCCGCTCAAGGTTACCTTATTGATAAGAAAACCGCTGAAAAGTACAACATCA
CTAACATAGGTCAATTGACTGATCCAAAAATCGCTAAGCTGTTTGATGCTGATGGTGATGGCAAAGCAGACCTGACGGGC
TGTAACCCTGGTTGGGGTTGTGAGATGGTCATCGAACACCAAATCTCTGCATTCAAATTGGACGATACCGTTACTCACAA
CCAAGGTAACTATGCAGCGATCATCGCAGATACGATTTCACGTTACCAAAAGGGCGAGTCAGTTCTTTACTACACGTGGA
CACCTTATTGGGTAAGTGGTGTATTGGTTCCTAACGAAGACGTAGTTTGGTTAGAAGTTCCATTCTCTTCACTTCCGGGT
GATCGTGCGAATGTTGATACTACTTTGTCTAACGGTAAGAACTACGGCTTCGAAATGAACTCGATGCGTATTATTGCGAA
CAAAGAGTTTGCTAAGAACAACCCATCTGCGGCGAAGCTTTTTGAAATCATCAAACTTAACATCAATGATGTAAGTGCTC
AGAACATGATGATGAGTAAAGGTAAGAACAGCTCGGCTGATATCGAAGCGCACGTAAACGGTTGGATCAAAGCGAACCGA
AATACGTTTGATGCTTGGATTACAGAAGCGAAGAAAGCGGCACTATAA

Upstream 100 bases:

>100_bases
AATACAAAATTACGCTGGTATCACATGGGGCCTGTTTCCCTTGTGCTAAAAGCTTTAAATCGCGGTAAACAATCAGAACT
ACAACTAAGGAAAAACACCA

Downstream 100 bases:

>100_bases
CGGTTGTTTTTCGTAAGCAGTCGATAACAGGCTGGAATAAAAAGAGAAGGCCGGTAGTCTGATTCAGACTACCGGCCTTT
GTTTTTCTAGCGACATAACT

Product: glycine betaine transporter periplasmic subunit

Products: ADP; phosphate; L-proline [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 335; Mature: 335

Protein sequence:

>335_residues
MNNSWKSKLAVSIVSTLAVSTNVWAASLPGEGVSVQPVQSSVAEETFQTLIVNRALEELGYDVKSTQEVDYNVAYTSIAK
GDATFLTVGWFPLHADKYKMAGGDDKFYREGQYVSGAAQGYLIDKKTAEKYNITNIGQLTDPKIAKLFDADGDGKADLTG
CNPGWGCEMVIEHQISAFKLDDTVTHNQGNYAAIIADTISRYQKGESVLYYTWTPYWVSGVLVPNEDVVWLEVPFSSLPG
DRANVDTTLSNGKNYGFEMNSMRIIANKEFAKNNPSAAKLFEIIKLNINDVSAQNMMMSKGKNSSADIEAHVNGWIKANR
NTFDAWITEAKKAAL

Sequences:

>Translated_335_residues
MNNSWKSKLAVSIVSTLAVSTNVWAASLPGEGVSVQPVQSSVAEETFQTLIVNRALEELGYDVKSTQEVDYNVAYTSIAK
GDATFLTVGWFPLHADKYKMAGGDDKFYREGQYVSGAAQGYLIDKKTAEKYNITNIGQLTDPKIAKLFDADGDGKADLTG
CNPGWGCEMVIEHQISAFKLDDTVTHNQGNYAAIIADTISRYQKGESVLYYTWTPYWVSGVLVPNEDVVWLEVPFSSLPG
DRANVDTTLSNGKNYGFEMNSMRIIANKEFAKNNPSAAKLFEIIKLNINDVSAQNMMMSKGKNSSADIEAHVNGWIKANR
NTFDAWITEAKKAAL
>Mature_335_residues
MNNSWKSKLAVSIVSTLAVSTNVWAASLPGEGVSVQPVQSSVAEETFQTLIVNRALEELGYDVKSTQEVDYNVAYTSIAK
GDATFLTVGWFPLHADKYKMAGGDDKFYREGQYVSGAAQGYLIDKKTAEKYNITNIGQLTDPKIAKLFDADGDGKADLTG
CNPGWGCEMVIEHQISAFKLDDTVTHNQGNYAAIIADTISRYQKGESVLYYTWTPYWVSGVLVPNEDVVWLEVPFSSLPG
DRANVDTTLSNGKNYGFEMNSMRIIANKEFAKNNPSAAKLFEIIKLNINDVSAQNMMMSKGKNSSADIEAHVNGWIKANR
NTFDAWITEAKKAAL

Specific function: Member of a multicomponent binding-protein-dependent transport system (the proU transporter) which serves as the glycine betaine/L-proline transporter [H]

COG id: COG2113

COG function: function code E; ABC-type proline/glycine betaine transport systems, periplasmic components

Gene ontology:

Cell location: Periplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Escherichia coli, GI1789034, Length=327, Percent_Identity=63.914373088685, Blast_Score=448, Evalue=1e-127,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR007210 [H]

Pfam domain/function: PF04069 OpuAC [H]

EC number: NA

Molecular weight: Translated: 36821; Mature: 36821

Theoretical pI: Translated: 4.94; Mature: 4.94

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNNSWKSKLAVSIVSTLAVSTNVWAASLPGEGVSVQPVQSSVAEETFQTLIVNRALEELG
CCCCHHHHHHHHHHHHHHHHCCCEEEECCCCCEEECHHHHHHHHHHHHHHHHHHHHHHHC
YDVKSTQEVDYNVAYTSIAKGDATFLTVGWFPLHADKYKMAGGDDKFYREGQYVSGAAQG
CCCCCCCCCCEEEEEEEECCCCEEEEEEEEEEECCCCEEECCCCHHHHCCCCEECCCCCE
YLIDKKTAEKYNITNIGQLTDPKIAKLFDADGDGKADLTGCNPGWGCEMVIEHQISAFKL
EEEECCCCCCCCCCCCCCCCCCHHHHEECCCCCCCEEECCCCCCCCCEEEEECCCCEEEE
DDTVTHNQGNYAAIIADTISRYQKGESVLYYTWTPYWVSGVLVPNEDVVWLEVPFSSLPG
CCCEEECCCCEEEEEEHHHHHHHCCCEEEEEEECHHHEEEEEECCCCEEEEEECHHHCCC
DRANVDTTLSNGKNYGFEMNSMRIIANKEFAKNNPSAAKLFEIIKLNINDVSAQNMMMSK
CCCCCCEECCCCCCCCEEECCEEEEECCCCCCCCCCHHHHHHEEEECCCCCCHHHHHHHC
GKNSSADIEAHVNGWIKANRNTFDAWITEAKKAAL
CCCCCCCEEEEECEEEEECCCCHHHHHHHHHHHCC
>Mature Secondary Structure
MNNSWKSKLAVSIVSTLAVSTNVWAASLPGEGVSVQPVQSSVAEETFQTLIVNRALEELG
CCCCHHHHHHHHHHHHHHHHCCCEEEECCCCCEEECHHHHHHHHHHHHHHHHHHHHHHHC
YDVKSTQEVDYNVAYTSIAKGDATFLTVGWFPLHADKYKMAGGDDKFYREGQYVSGAAQG
CCCCCCCCCCEEEEEEEECCCCEEEEEEEEEEECCCCEEECCCCHHHHCCCCEECCCCCE
YLIDKKTAEKYNITNIGQLTDPKIAKLFDADGDGKADLTGCNPGWGCEMVIEHQISAFKL
EEEECCCCCCCCCCCCCCCCCCHHHHEECCCCCCCEEECCCCCCCCCEEEEECCCCEEEE
DDTVTHNQGNYAAIIADTISRYQKGESVLYYTWTPYWVSGVLVPNEDVVWLEVPFSSLPG
CCCEEECCCCEEEEEEHHHHHHHCCCEEEEEEECHHHEEEEEECCCCEEEEEECHHHCCC
DRANVDTTLSNGKNYGFEMNSMRIIANKEFAKNNPSAAKLFEIIKLNINDVSAQNMMMSK
CCCCCCEECCCCCCCCEEECCEEEEECCCCCCCCCCHHHHHHEEEECCCCCCHHHHHHHC
GKNSSADIEAHVNGWIKANRNTFDAWITEAKKAAL
CCCCCCCEEEEECEEEEECCCCHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; L-proline [Periplasm]; H2O [C]

Specific reaction: ATP + L-proline [Periplasm] + H2O = ADP + phosphate + L-proline [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]