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The map label for this gene is torR [H]

Identifier: 218709085

GI number: 218709085

Start: 1148692

End: 1149405

Strand: Direct

Name: torR [H]

Synonym: VS_1091

Alternate gene names: 218709085

Gene position: 1148692-1149405 (Clockwise)

Preceding gene: 218709078

Following gene: 218709087

Centisome position: 34.82

GC content: 44.12

Gene sequence:

>714_bases
ATGAGCTATCACGTATTAGTCGTAGAAGATGATGTGGTAACCCGAAGTAAACTGGTTGGATATTTCCAGAATGAAGGTTA
CACAGTGAGCGAAGCTGAAAGCGGGGCTCAAATGAGAAAAATGTTAGAAGAAAATAACGTTGACCTCATTATGTTAGACA
TCAACTTGCCAGGCGAAGATGGATTGATGCTAACTCGCGAATTACGCAGTCAATCAGACATTGGAATAATTTTAGTTACT
GGACGCACGGATAGCATTGACAAGATCGTTGGCCTTGAAATGGGCGCAGACGATTACGTTACTAAACCCTTCGAACTTCG
CGAGTTGTTGGTTCGAGTTAAAAACCTCTTGTGGCGTATTTCGGCTGCTCGTAAAACTGCAGCGGTTGCGGTAGAACAAA
CAGAAGACGAATCTGTGGTTCGTTTTGGTGAATGGACGTTTGATATACCTCGCCGTGCGCTAAGCAAGAACAGCGAGCCG
GTGAAATTGACCAAAGCTGAATATGAACTATTGGTTGCACTCTCTTCTTACCCTAACCAAGTATTAAGCCGTGAACGTAT
TTTGAATATGATCAGCCATCGAGTAGACGCGCCGAATGACCGCACTATCGACGTGTTAATCCGTCGTATGCGTGCAAAAA
TGGAGTTTGACCCTAAGAACCCACAAATTTTTGTGACGGTTCACGGTGAAGGTTACATGTTTGCTGGTGACTAA

Upstream 100 bases:

>100_bases
AAAAATCATGTTTCTGGCTTTTATCTTCTGTAGTACTAGAATTGTTACGAGTTATGAATAGAATGGTCACTGAAACTATT
AAATAAGAAAAGTGGTGTAG

Downstream 100 bases:

>100_bases
TTTCCCGTGGAAAGCTGATTTCAGTAACGATACTTGAACGAAAAAAAACCGAGACATCAATGATGCCTCGGTTTTTTTGT
TACTGAACTTTTTAATTGTT

Product: DNA-binding transcriptional regulator TorR

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 237; Mature: 236

Protein sequence:

>237_residues
MSYHVLVVEDDVVTRSKLVGYFQNEGYTVSEAESGAQMRKMLEENNVDLIMLDINLPGEDGLMLTRELRSQSDIGIILVT
GRTDSIDKIVGLEMGADDYVTKPFELRELLVRVKNLLWRISAARKTAAVAVEQTEDESVVRFGEWTFDIPRRALSKNSEP
VKLTKAEYELLVALSSYPNQVLSRERILNMISHRVDAPNDRTIDVLIRRMRAKMEFDPKNPQIFVTVHGEGYMFAGD

Sequences:

>Translated_237_residues
MSYHVLVVEDDVVTRSKLVGYFQNEGYTVSEAESGAQMRKMLEENNVDLIMLDINLPGEDGLMLTRELRSQSDIGIILVT
GRTDSIDKIVGLEMGADDYVTKPFELRELLVRVKNLLWRISAARKTAAVAVEQTEDESVVRFGEWTFDIPRRALSKNSEP
VKLTKAEYELLVALSSYPNQVLSRERILNMISHRVDAPNDRTIDVLIRRMRAKMEFDPKNPQIFVTVHGEGYMFAGD
>Mature_236_residues
SYHVLVVEDDVVTRSKLVGYFQNEGYTVSEAESGAQMRKMLEENNVDLIMLDINLPGEDGLMLTRELRSQSDIGIILVTG
RTDSIDKIVGLEMGADDYVTKPFELRELLVRVKNLLWRISAARKTAAVAVEQTEDESVVRFGEWTFDIPRRALSKNSEPV
KLTKAEYELLVALSSYPNQVLSRERILNMISHRVDAPNDRTIDVLIRRMRAKMEFDPKNPQIFVTVHGEGYMFAGD

Specific function: Member of the two-component regulatory system torS/torR involved in the anaerobic utilization of trimethylamine-N-oxide (TMAO). Phosphorylated torR activates the transcription of the torCAD operon by binding to four decameric boxes located in the torCAD p

COG id: COG0745

COG function: function code TK; Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1787229, Length=238, Percent_Identity=56.3025210084034, Blast_Score=267, Evalue=4e-73,
Organism=Escherichia coli, GI1790863, Length=235, Percent_Identity=44.2553191489362, Blast_Score=213, Evalue=7e-57,
Organism=Escherichia coli, GI1789809, Length=237, Percent_Identity=39.662447257384, Blast_Score=179, Evalue=1e-46,
Organism=Escherichia coli, GI1788394, Length=233, Percent_Identity=36.480686695279, Blast_Score=142, Evalue=1e-35,
Organism=Escherichia coli, GI1786599, Length=238, Percent_Identity=34.0336134453782, Blast_Score=127, Evalue=5e-31,
Organism=Escherichia coli, GI1786911, Length=233, Percent_Identity=33.9055793991416, Blast_Score=125, Evalue=2e-30,
Organism=Escherichia coli, GI1787375, Length=232, Percent_Identity=34.4827586206897, Blast_Score=124, Evalue=4e-30,
Organism=Escherichia coli, GI1790860, Length=233, Percent_Identity=30.9012875536481, Blast_Score=115, Evalue=2e-27,
Organism=Escherichia coli, GI1790552, Length=234, Percent_Identity=32.4786324786325, Blast_Score=108, Evalue=2e-25,
Organism=Escherichia coli, GI1786784, Length=231, Percent_Identity=32.4675324675325, Blast_Score=105, Evalue=3e-24,
Organism=Escherichia coli, GI87082012, Length=232, Percent_Identity=29.3103448275862, Blast_Score=104, Evalue=4e-24,
Organism=Escherichia coli, GI145693140, Length=231, Percent_Identity=30.3030303030303, Blast_Score=104, Evalue=6e-24,
Organism=Escherichia coli, GI2367329, Length=232, Percent_Identity=28.8793103448276, Blast_Score=95, Evalue=4e-21,
Organism=Escherichia coli, GI1789402, Length=232, Percent_Identity=28.0172413793103, Blast_Score=89, Evalue=4e-19,
Organism=Escherichia coli, GI1790299, Length=111, Percent_Identity=30.6306306306306, Blast_Score=61, Evalue=6e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR001867
- InterPro:   IPR001789
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00072 Response_reg; PF00486 Trans_reg_C [H]

EC number: NA

Molecular weight: Translated: 26954; Mature: 26823

Theoretical pI: Translated: 4.84; Mature: 4.84

Prosite motif: PS50110 RESPONSE_REGULATORY

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
4.2 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.8 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSYHVLVVEDDVVTRSKLVGYFQNEGYTVSEAESGAQMRKMLEENNVDLIMLDINLPGED
CCEEEEEEECCHHHHHHHHEEECCCCEEECCCCCHHHHHHHHHHCCCCEEEEEEECCCCC
GLMLTRELRSQSDIGIILVTGRTDSIDKIVGLEMGADDYVTKPFELRELLVRVKNLLWRI
CEEEEHHHCCCCCCEEEEEECCCCCCHHHEEEECCCCCCCCCCHHHHHHHHHHHHHHHHH
SAARKTAAVAVEQTEDESVVRFGEWTFDIPRRALSKNSEPVKLTKAEYELLVALSSYPNQ
HHHHHEEEEEEECCCCCCEEEECCEEECCCHHHHCCCCCCEEEECCCEEEEEEEHHCCHH
VLSRERILNMISHRVDAPNDRTIDVLIRRMRAKMEFDPKNPQIFVTVHGEGYMFAGD
HHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHCCCCCCCCEEEEEECCCEEEEECC
>Mature Secondary Structure 
SYHVLVVEDDVVTRSKLVGYFQNEGYTVSEAESGAQMRKMLEENNVDLIMLDINLPGED
CEEEEEEECCHHHHHHHHEEECCCCEEECCCCCHHHHHHHHHHCCCCEEEEEEECCCCC
GLMLTRELRSQSDIGIILVTGRTDSIDKIVGLEMGADDYVTKPFELRELLVRVKNLLWRI
CEEEEHHHCCCCCCEEEEEECCCCCCHHHEEEECCCCCCCCCCHHHHHHHHHHHHHHHHH
SAARKTAAVAVEQTEDESVVRFGEWTFDIPRRALSKNSEPVKLTKAEYELLVALSSYPNQ
HHHHHEEEEEEECCCCCCEEEECCEEECCCHHHHCCCCCCEEEECCCEEEEEEEHHCCHH
VLSRERILNMISHRVDAPNDRTIDVLIRRMRAKMEFDPKNPQIFVTVHGEGYMFAGD
HHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHCCCCCCCCEEEEEECCCEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]