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The map label for this gene is nqrA

Identifier: 218708714

GI number: 218708714

Start: 727124

End: 728464

Strand: Direct

Name: nqrA

Synonym: VS_0693

Alternate gene names: 218708714

Gene position: 727124-728464 (Clockwise)

Preceding gene: 218708713

Following gene: 218708715

Centisome position: 22.04

GC content: 44.67

Gene sequence:

>1341_bases
ATGATTACAATAAAGAAGGGTTTGGATCTTCCTATCGCAGGAACTCCATCCCAGGTGATTAATGATGGTAAGTCCATCAC
TAAAGTCGCCTTGCTTGGCGAAGAGTACGTTGGTATGCGTCCTACGATGCATGCTCGCGTTGGTGATGAAGTGAAGAAAG
GCCAAGTTCTTTTTGCAGATAAAAAGAACCCAGGTGTTGTATTTACTTCTCCAGCAAGCGGTAAAGTTATTGAAGTGAAC
CGTGGTGCTAAGCGTGTTCTTCAATCAGTAGTGATTGAAGTAGCAGGCAATGAGCAAATCACGTTCAATAGCTATGAAGC
TAACCAACTAGTAAGTCTTGACCGTGAAACGGTTAAAACTCAGTTAGTTGAGTCTGGCGCATGGACCGCTTTGCGAACTC
GTCCGTTCAGCAAGGTTCCAGCAGTTGATTCTGAAACTCAGGCTATTTTCGTTACTGCTATGGATACTAATCCGCTAGCA
GCTGAGCCAGAATTAATCATTAACGAGCAGTCTGATGCTTTCGTTGCTGGTTTAGATCTTCTTTCAACTCTGACTAACGG
TAAAGTGTACGTTTGTAAAAAAGGTACTAGCTTACCTCGTTCAGCTCAGTCTAACGTTGAAGAACATGTTTTTGATGGCC
CACACCCTGCAGGTCTTGCAGGCACGCATATGCATTACCTATATCCGGTAAATGCACAAAATGTAGCGTGGAGCATTAAC
TACCAAGATGTTATCGCATTCGGTAAGCTTTTCCTTACTGGTGAGATTTACTCTGAGCGTGTTGTTTCTCTGGCTGGTCC
AGTGGTGAATAACCCACGTCTAGTTCGTACTCAAATTGGTGCTAGCCTTGAAGAGTTGACAGACAGCGAGTTAATGCCAG
GCGAAGTTCGTGTGATTTCTGGTTCTGTACTTACGGGTACTGAAGCAACAGGTCCACATGCTTTCCTTGGTCGTTACCAT
CAGCAAGTTTCTGTTCTACGTGAAGGTCGTGATAAAGAGCTATTCGGCTGGGCTATGCCTGGTAAGAACAAGTTCTCTGT
TACTCGTTCATTCCTTGGTCACCTGTTTAAAGGTCAGTTGTTCAACATGACAACGACGACAAACGGTAGTGACCGCTCAA
TGGTTCCAATTGGTAACTACGAGCGCGTAATGCCTCTAGATATGGAACCTACATTGCTGCTTCGAGATCTATGTGCAGGC
GACATTGATAGTGCTCAAGCACTTGGTGCGCTAGAACTAGACGAAGAAGATGTAGCATTGTGTACCTTTGTATGTCCAGG
TAAGTACGAGTACGGTCAACTACTTCGTGAATGCCTAGATACGATTGAGAAGGAAGGGTAA

Upstream 100 bases:

>100_bases
AAACCGGACACTGTAATGTCGTGTCTAAGGGCGATTTTAAAACGTCCCGAATTTACGCAATTAAAAGAATCTTTTTCCCG
ATAAAGTAGTGCAAGTGCGT

Downstream 100 bases:

>100_bases
TTTTCATGGGCCTTAAAAAGTTTCTTGAAGACATCGAGCATCATTTTGAGCCAGGTGGTAAACACGAGAAGTGGTTTGCG
CTTTACGAAGCAGCAGCGAC

Product: Na(+)-translocating NADH-quinone reductase subunit A

Products: NA

Alternate protein names: Na(+)-NQR subunit A; Na(+)-translocating NQR subunit A; NQR complex subunit A; NQR-1 subunit A

Number of amino acids: Translated: 446; Mature: 446

Protein sequence:

>446_residues
MITIKKGLDLPIAGTPSQVINDGKSITKVALLGEEYVGMRPTMHARVGDEVKKGQVLFADKKNPGVVFTSPASGKVIEVN
RGAKRVLQSVVIEVAGNEQITFNSYEANQLVSLDRETVKTQLVESGAWTALRTRPFSKVPAVDSETQAIFVTAMDTNPLA
AEPELIINEQSDAFVAGLDLLSTLTNGKVYVCKKGTSLPRSAQSNVEEHVFDGPHPAGLAGTHMHYLYPVNAQNVAWSIN
YQDVIAFGKLFLTGEIYSERVVSLAGPVVNNPRLVRTQIGASLEELTDSELMPGEVRVISGSVLTGTEATGPHAFLGRYH
QQVSVLREGRDKELFGWAMPGKNKFSVTRSFLGHLFKGQLFNMTTTTNGSDRSMVPIGNYERVMPLDMEPTLLLRDLCAG
DIDSAQALGALELDEEDVALCTFVCPGKYEYGQLLRECLDTIEKEG

Sequences:

>Translated_446_residues
MITIKKGLDLPIAGTPSQVINDGKSITKVALLGEEYVGMRPTMHARVGDEVKKGQVLFADKKNPGVVFTSPASGKVIEVN
RGAKRVLQSVVIEVAGNEQITFNSYEANQLVSLDRETVKTQLVESGAWTALRTRPFSKVPAVDSETQAIFVTAMDTNPLA
AEPELIINEQSDAFVAGLDLLSTLTNGKVYVCKKGTSLPRSAQSNVEEHVFDGPHPAGLAGTHMHYLYPVNAQNVAWSIN
YQDVIAFGKLFLTGEIYSERVVSLAGPVVNNPRLVRTQIGASLEELTDSELMPGEVRVISGSVLTGTEATGPHAFLGRYH
QQVSVLREGRDKELFGWAMPGKNKFSVTRSFLGHLFKGQLFNMTTTTNGSDRSMVPIGNYERVMPLDMEPTLLLRDLCAG
DIDSAQALGALELDEEDVALCTFVCPGKYEYGQLLRECLDTIEKEG
>Mature_446_residues
MITIKKGLDLPIAGTPSQVINDGKSITKVALLGEEYVGMRPTMHARVGDEVKKGQVLFADKKNPGVVFTSPASGKVIEVN
RGAKRVLQSVVIEVAGNEQITFNSYEANQLVSLDRETVKTQLVESGAWTALRTRPFSKVPAVDSETQAIFVTAMDTNPLA
AEPELIINEQSDAFVAGLDLLSTLTNGKVYVCKKGTSLPRSAQSNVEEHVFDGPHPAGLAGTHMHYLYPVNAQNVAWSIN
YQDVIAFGKLFLTGEIYSERVVSLAGPVVNNPRLVRTQIGASLEELTDSELMPGEVRVISGSVLTGTEATGPHAFLGRYH
QQVSVLREGRDKELFGWAMPGKNKFSVTRSFLGHLFKGQLFNMTTTTNGSDRSMVPIGNYERVMPLDMEPTLLLRDLCAG
DIDSAQALGALELDEEDVALCTFVCPGKYEYGQLLRECLDTIEKEG

Specific function: NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm. NqrA to nqrE are probably involved in the second step, the conversion of ubisemiqui

COG id: COG1726

COG function: function code C; Na+-transporting NADH:ubiquinone oxidoreductase, subunit NqrA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the nqrA family

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NQRA_VIBSL (B7VKD2)

Other databases:

- EMBL:   FM954972
- RefSeq:   YP_002416335.1
- GeneID:   7160312
- GenomeReviews:   FM954972_GR
- KEGG:   vsp:VS_0693
- HOGENOM:   HBG413878
- OMA:   EYGPILR
- ProtClustDB:   PRK05352
- HAMAP:   MF_00425
- InterPro:   IPR008703
- InterPro:   IPR022615
- TIGRFAMs:   TIGR01936

Pfam domain/function: PF05896 NQRA; PF11973 NQRA_SLBB

EC number: NA

Molecular weight: Translated: 48535; Mature: 48535

Theoretical pI: Translated: 5.10; Mature: 5.10

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MITIKKGLDLPIAGTPSQVINDGKSITKVALLGEEYVGMRPTMHARVGDEVKKGQVLFAD
CEEECCCCCCCCCCCCHHHHCCCCCEEEEEEECHHHCCCCCCCHHHCCCCHHCCEEEEEE
KKNPGVVFTSPASGKVIEVNRGAKRVLQSVVIEVAGNEQITFNSYEANQLVSLDRETVKT
CCCCCEEEECCCCCCEEEECCCHHHHHHHHHHEECCCCEEEEECCCCCHHHHHHHHHHHH
QLVESGAWTALRTRPFSKVPAVDSETQAIFVTAMDTNPLAAEPELIINEQSDAFVAGLDL
HHHHCCCCEEEECCCCCCCCCCCCCCCEEEEEEECCCCCCCCCCEEEECCCCHHHHHHHH
LSTLTNGKVYVCKKGTSLPRSAQSNVEEHVFDGPHPAGLAGTHMHYLYPVNAQNVAWSIN
HHHHCCCEEEEEECCCCCCCHHHCCHHHHHCCCCCCCCCCCCCEEEEEEECCCCEEEEEC
YQDVIAFGKLFLTGEIYSERVVSLAGPVVNNPRLVRTQIGASLEELTDSELMPGEVRVIS
HHHHHHHHHHEEECHHHHHHHHHHCCCCCCCCEEEEEHHCCCHHHHCCCCCCCCEEEEEE
GSVLTGTEATGPHAFLGRYHQQVSVLREGRDKELFGWAMPGKNKFSVTRSFLGHLFKGQL
CCEEECCCCCCCHHHHHHHHHHHHHHHCCCCCCEEEEECCCCCHHHHHHHHHHHHHCCCE
FNMTTTTNGSDRSMVPIGNYERVMPLDMEPTLLLRDLCAGDIDSAQALGALELDEEDVAL
EEEEECCCCCCCEEEECCCCCEEEECCCCHHHHHHHHHCCCCCCHHHCCEEEECCCCEEE
CTFVCPGKYEYGQLLRECLDTIEKEG
EEEECCCCCHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MITIKKGLDLPIAGTPSQVINDGKSITKVALLGEEYVGMRPTMHARVGDEVKKGQVLFAD
CEEECCCCCCCCCCCCHHHHCCCCCEEEEEEECHHHCCCCCCCHHHCCCCHHCCEEEEEE
KKNPGVVFTSPASGKVIEVNRGAKRVLQSVVIEVAGNEQITFNSYEANQLVSLDRETVKT
CCCCCEEEECCCCCCEEEECCCHHHHHHHHHHEECCCCEEEEECCCCCHHHHHHHHHHHH
QLVESGAWTALRTRPFSKVPAVDSETQAIFVTAMDTNPLAAEPELIINEQSDAFVAGLDL
HHHHCCCCEEEECCCCCCCCCCCCCCCEEEEEEECCCCCCCCCCEEEECCCCHHHHHHHH
LSTLTNGKVYVCKKGTSLPRSAQSNVEEHVFDGPHPAGLAGTHMHYLYPVNAQNVAWSIN
HHHHCCCEEEEEECCCCCCCHHHCCHHHHHCCCCCCCCCCCCCEEEEEEECCCCEEEEEC
YQDVIAFGKLFLTGEIYSERVVSLAGPVVNNPRLVRTQIGASLEELTDSELMPGEVRVIS
HHHHHHHHHHEEECHHHHHHHHHHCCCCCCCCEEEEEHHCCCHHHHCCCCCCCCEEEEEE
GSVLTGTEATGPHAFLGRYHQQVSVLREGRDKELFGWAMPGKNKFSVTRSFLGHLFKGQL
CCEEECCCCCCCHHHHHHHHHHHHHHHCCCCCCEEEEECCCCCHHHHHHHHHHHHHCCCE
FNMTTTTNGSDRSMVPIGNYERVMPLDMEPTLLLRDLCAGDIDSAQALGALELDEEDVAL
EEEEECCCCCCCEEEECCCCCEEEECCCCHHHHHHHHHCCCCCCHHHCCEEEECCCCEEE
CTFVCPGKYEYGQLLRECLDTIEKEG
EEEECCCCCHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA