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The map label for this gene is ygdL [H]

Identifier: 218708702

GI number: 218708702

Start: 715752

End: 716561

Strand: Direct

Name: ygdL [H]

Synonym: VS_0681

Alternate gene names: 218708702

Gene position: 715752-716561 (Clockwise)

Preceding gene: 218708701

Following gene: 218708703

Centisome position: 21.69

GC content: 47.16

Gene sequence:

>810_bases
ATGCGTGAATTGACCACTCCAGCTTCAGAAAACTATGACCAACGATTTGGTGGCACTCGTCGCCTGTATGGCAATAGTGA
AGTCGATATACTTAGAGCAGCACACGTGTGTGTGATCGGTATTGGCGGTGTCGGTTCATGGGCGGTTGAAGCGCTTGCTC
GTACTGGTTTAGGTGAGCTGACATTGATCGATATGGATGATGTGTGCGTGACGAACATTAACCGTCAAATCCACGCAATG
TCGGGCACGGTTGGTAAGAGTAAAATCGAAGTGATGGCAGAGCGCGTTAAGCTGATTAACCCTGAGTGTAAAGTGAACCT
GATCGACGACTTTATTGGTCCTGATAATCAGGCTGAATACCTATCGAAAGAGTTCGACTTTGTGCTCGATGCGATTGATA
GCATGAAAGCTAAGGCTTCGCTGTTGGCGTATTGCCGTAGCAACAAAATTAAAGTGATCACCACCGGTGGCGCGGGTGGA
CAAATCGATCCGACTCAAATCAAAGTGGCTGATCTGACTAAAACGATTCAAGATCCGTTAGCGAAGAAATTGAAAGACAC
ATTGCGTCGTCATCATAATTTCCCTAAGAATCCAGCGCGTAAGTTTGGTATCGATTGTGTGTTCTCGACTGAGCAACTTA
AGTACCCACAAGCTGACGGCAGTGTATGTGCTGCGAAAGCAACCGCAGAAGGTCCAAAGCGAATGGATTGTGCGACGGGT
TTTGGTGCAGCAACGGTTGTCACGGCTACCTTTGGTTTTGTGGCGGTTTCACGTATCGTAGAAAAGATCGTTCAAAAGCA
CGCTAAGTAA

Upstream 100 bases:

>100_bases
GGGGCATTGAAAGCGAATCGCTAATCCCCTAGACTTTTAATTCAAGAGTGCGTATAAAACGCACTCTTTTCTTTTTCTCA
GAAATAAATTGGCGGCAACA

Downstream 100 bases:

>100_bases
CGTCTTCTTCTCAATTAACAATCGACTGGATATTAAAATGACCACATTCCCAAGCTTTCCATTCGGCAAAGAAATTACCA
GTGATGATATTGTCGCAAAA

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 269; Mature: 269

Protein sequence:

>269_residues
MRELTTPASENYDQRFGGTRRLYGNSEVDILRAAHVCVIGIGGVGSWAVEALARTGLGELTLIDMDDVCVTNINRQIHAM
SGTVGKSKIEVMAERVKLINPECKVNLIDDFIGPDNQAEYLSKEFDFVLDAIDSMKAKASLLAYCRSNKIKVITTGGAGG
QIDPTQIKVADLTKTIQDPLAKKLKDTLRRHHNFPKNPARKFGIDCVFSTEQLKYPQADGSVCAAKATAEGPKRMDCATG
FGAATVVTATFGFVAVSRIVEKIVQKHAK

Sequences:

>Translated_269_residues
MRELTTPASENYDQRFGGTRRLYGNSEVDILRAAHVCVIGIGGVGSWAVEALARTGLGELTLIDMDDVCVTNINRQIHAM
SGTVGKSKIEVMAERVKLINPECKVNLIDDFIGPDNQAEYLSKEFDFVLDAIDSMKAKASLLAYCRSNKIKVITTGGAGG
QIDPTQIKVADLTKTIQDPLAKKLKDTLRRHHNFPKNPARKFGIDCVFSTEQLKYPQADGSVCAAKATAEGPKRMDCATG
FGAATVVTATFGFVAVSRIVEKIVQKHAK
>Mature_269_residues
MRELTTPASENYDQRFGGTRRLYGNSEVDILRAAHVCVIGIGGVGSWAVEALARTGLGELTLIDMDDVCVTNINRQIHAM
SGTVGKSKIEVMAERVKLINPECKVNLIDDFIGPDNQAEYLSKEFDFVLDAIDSMKAKASLLAYCRSNKIKVITTGGAGG
QIDPTQIKVADLTKTIQDPLAKKLKDTLRRHHNFPKNPARKFGIDCVFSTEQLKYPQADGSVCAAKATAEGPKRMDCATG
FGAATVVTATFGFVAVSRIVEKIVQKHAK

Specific function: Unknown

COG id: COG1179

COG function: function code H; Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 1

Gene ontology:

Cell location: Membrane; Single-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the hesA/moeB/thiF family [H]

Homologues:

Organism=Homo sapiens, GI4885649, Length=132, Percent_Identity=33.3333333333333, Blast_Score=73, Evalue=3e-13,
Organism=Escherichia coli, GI1789177, Length=261, Percent_Identity=65.5172413793103, Blast_Score=372, Evalue=1e-104,
Organism=Escherichia coli, GI1787048, Length=124, Percent_Identity=32.258064516129, Blast_Score=74, Evalue=7e-15,
Organism=Escherichia coli, GI87082356, Length=131, Percent_Identity=30.5343511450382, Blast_Score=66, Evalue=3e-12,
Organism=Saccharomyces cerevisiae, GI6321790, Length=192, Percent_Identity=26.5625, Blast_Score=92, Evalue=9e-20,
Organism=Saccharomyces cerevisiae, GI6322825, Length=165, Percent_Identity=31.5151515151515, Blast_Score=87, Evalue=2e-18,
Organism=Saccharomyces cerevisiae, GI6322639, Length=203, Percent_Identity=27.0935960591133, Blast_Score=64, Evalue=3e-11,
Organism=Drosophila melanogaster, GI24660640, Length=137, Percent_Identity=29.9270072992701, Blast_Score=75, Evalue=6e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR009036
- InterPro:   IPR016040
- InterPro:   IPR000594 [H]

Pfam domain/function: PF00899 ThiF [H]

EC number: NA

Molecular weight: Translated: 29191; Mature: 29191

Theoretical pI: Translated: 8.66; Mature: 8.66

Prosite motif: PS00228 TUBULIN_B_AUTOREG

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.6 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
4.8 %Cys+Met (Translated Protein)
2.6 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
4.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRELTTPASENYDQRFGGTRRLYGNSEVDILRAAHVCVIGIGGVGSWAVEALARTGLGEL
CCCCCCCCCCCCHHHCCCCEEECCCCCHHHHHHCEEEEEEECCCHHHHHHHHHHCCCCCE
TLIDMDDVCVTNINRQIHAMSGTVGKSKIEVMAERVKLINPECKVNLIDDFIGPDNQAEY
EEEECCCHHHHCCCCEEEECCCCCCHHHHHHHHHHHHHCCCCCEEEEHHHCCCCCCHHHH
LSKEFDFVLDAIDSMKAKASLLAYCRSNKIKVITTGGAGGQIDPTQIKVADLTKTIQDPL
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCCCCCCCEEEHHHHHHHHHHHH
AKKLKDTLRRHHNFPKNPARKFGIDCVFSTEQLKYPQADGSVCAAKATAEGPKRMDCATG
HHHHHHHHHHHCCCCCCCHHHHCCEEEEEHHHHCCCCCCCCEEEECCCCCCCCCCHHHCC
FGAATVVTATFGFVAVSRIVEKIVQKHAK
CCHHHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MRELTTPASENYDQRFGGTRRLYGNSEVDILRAAHVCVIGIGGVGSWAVEALARTGLGEL
CCCCCCCCCCCCHHHCCCCEEECCCCCHHHHHHCEEEEEEECCCHHHHHHHHHHCCCCCE
TLIDMDDVCVTNINRQIHAMSGTVGKSKIEVMAERVKLINPECKVNLIDDFIGPDNQAEY
EEEECCCHHHHCCCCEEEECCCCCCHHHHHHHHHHHHHCCCCCEEEEHHHCCCCCCHHHH
LSKEFDFVLDAIDSMKAKASLLAYCRSNKIKVITTGGAGGQIDPTQIKVADLTKTIQDPL
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCCCCCCCEEEHHHHHHHHHHHH
AKKLKDTLRRHHNFPKNPARKFGIDCVFSTEQLKYPQADGSVCAAKATAEGPKRMDCATG
HHHHHHHHHHHCCCCCCCHHHHCCEEEEEHHHHCCCCCCCCEEEECCCCCCCCCCHHHCC
FGAATVVTATFGFVAVSRIVEKIVQKHAK
CCHHHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 9278503 [H]