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The map label for this gene is recD [H]

Identifier: 218708697

GI number: 218708697

Start: 709496

End: 711721

Strand: Direct

Name: recD [H]

Synonym: VS_0676

Alternate gene names: 218708697

Gene position: 709496-711721 (Clockwise)

Preceding gene: 218708696

Following gene: 218708700

Centisome position: 21.5

GC content: 46.41

Gene sequence:

>2226_bases
ATGACAACAACGACCACTAATACCAGTACAGAAGCTGCGAACACGCTAAAGCCAGTTTCACTTATCCCTGAGCAGCTCAT
GAATGTATTAAAGTTCCTAGCGGACAAAGGTTCAATTCGTCAGTTGGATTATCAATTTGCCCGTTTTATTGCTCAGCAAG
CGACGAGTCATTCTCAAGAGATCGGGTTTCTAGCTGGCGTTGTAAGCCATGAATTAGGCAAGGGGCATATTTGTACTCAG
CTTATACAGCAGCATAAGGCAGGCCCTGAACAAACGACAGATCTAGCCCAGTTGCTTGGTTTGTACGGTGAAACGGCACT
GCAATTGAACCAAAAACTGTTGGGTATTGATTGGGTGACTGTTCTGCAATCATCTAACCTAGTTGGAACAACTAATGACT
GCGTTAAGCCGCTGATGTTTGATGGGCAGCGTGTCTACTTACAGCGTTATTGGAACTACGAAGTTGTGTTGGCTGAAACT
CTAAACCGTTTAAGTAAGCCAGTAGAGTTCAATATTGAGCAGAAAAAAGCACTGACTGAGACGCTCAATCAGCTTTTTGC
ACGCAGTTATCACTTCCTGTTTAATGCCTTAACCAAGGCTGAAGCAAACCAACAAACCTCTCAGGTATTACGTCAGCAGT
TAGTGTGTGACCATCTAGATATCGTCGATGAACAGGCTTTGGATTGGGGTTCTATCGATCAAGCGATTGTTCAAGCCAAA
CAAGTGACCGATTTAGATGTGCTGGATAGTCTAGTGCCGTTATCTGTCTGTTTGAACTGGCAAAAAGTAGCGGCAGCGGT
GGCGTTAAGTCGTCGCTTCGCGGTGATTTCTGGTGGGCCGGGTACCGGTAAAACGACCACGGTAACTAAGTTGCTGTCGG
CGATGGTCGAGCAATCACTCAGCCAAGGTAAAATACCGACGATCAAGCTGGTGGCTCCGACAGGTAAAGCGGCGGCGCGT
TTAACTGAGTCGATTGGTAAAGCGATTGAACAATTACCTCTGGCGCCTGAAGTAAAGGCCAACATACCGACGGAATCGAG
CACTTTGCACCGATTACTTGGTGCGATCCCCAATCGAGCGGAGTTTAGACACAACCGACGTAATCCACTTCACCTTGATA
TCTTGGTGGTGGATGAAGCATCGATGGTCGACTTATCCATGATGTATAAGCTGGTGGATGCACTCCCTGAACACGCAAGG
TTGATTCTGCTTGGTGATAAAGACCAGCTCGCTTCAGTAGAAGCAGGTGCCGTGTTGGGTGATATCTGCTCGTTTAATTC
AACAGGCTACAGCACAGCGCAAGGTAACTTGATTGCGGAAATGACAGGCTTTGATGCGATAGCTAAACCCAGACAGGTCA
AAACAGGATCGGCTAACCCTCCTGCGATTGCCGATAGTTTGTGTATGCTGCAGAAGAGTTACCGTTTTGATGCACGTTCA
GGTATCGGACAGTTGGCAAAGGCGATCAATAACGGCTCTGCTAATCAGGTCGATCAAGTGTTTGCGAAAGGGTTTGCGGA
TATTGAGAATCATCCCTTGTCGAGTGACAGCTATAACTTGATGCTACGTACTTTAGTTAATGAATATGGTGCGTATCTGA
ACCGAATGAATGTGCCATTGGAAGAGCTAGAAACTCAAGAAGCGAGAGCGAAATCGGTTCTCGATTTGTTCAGCCAGTGT
CGGTTGCTGTGTTCCATTCGCGAAGGTGACTTTGGTGTTAAAGGCCTCAACCACAGAATCGAAAGGGCACTTGCCGCAAG
ACGCTTGGTGAATCCGAACAACGATGAATTGTGGTATCACGGGCGACCAGTAATGGTAACGCGCAATGATCATGGCTTAG
GTTTATACAATGGTGATATTGGTATCTGTATGCTTGAGGCTGATGTAAGTAGCTCTTCTTCAATTGATGATAACTCAGCC
CCTCGATTAAAGGTGTACTTTGAATTGCCCGATGGCAGTGTGAAAGCCGTGCTTCCAAGCAGAGTCCCCGATCATGAGAC
CGCTTATGCGATGACGATACACAAATCTCAAGGCAGTGAGTTTGATCTGACCTTAATGATCTTACCGCCAGACTTCAGCC
CTATTTTAACGCGAGAGCTTATCTATACCGGTATTACACGTGCTAAGAAACGACTGATTATGTTCAGCGACACAAATGTG
TTGAAGCGTGGGATTAAGGTGAAAACAGAGCGAGTGAGTGGTTTAGGAAGTCGATTAACTAACTGA

Upstream 100 bases:

>100_bases
CTTTGCTCGATGAAATGGATCAATTGATTGACGGTAAAGTGATAGACAGACGTTCAGCACAATTGAATGACAATGAAACT
GGACAGATGGGGCTTTTATA

Downstream 100 bases:

>100_bases
TGGTCAGTGGTTTTAGTGGAGGTGTTGCTGGAAGTAAAACTACGAAATAGCAGAGTAAATCGTATACACAAAGCAACCAT
CCGTGGTTGCTCTGAACGCT

Product: putative Exodeoxyribonuclease V subunit alpha

Products: NA

Alternate protein names: Exodeoxyribonuclease V 67 kDa polypeptide [H]

Number of amino acids: Translated: 741; Mature: 740

Protein sequence:

>741_residues
MTTTTTNTSTEAANTLKPVSLIPEQLMNVLKFLADKGSIRQLDYQFARFIAQQATSHSQEIGFLAGVVSHELGKGHICTQ
LIQQHKAGPEQTTDLAQLLGLYGETALQLNQKLLGIDWVTVLQSSNLVGTTNDCVKPLMFDGQRVYLQRYWNYEVVLAET
LNRLSKPVEFNIEQKKALTETLNQLFARSYHFLFNALTKAEANQQTSQVLRQQLVCDHLDIVDEQALDWGSIDQAIVQAK
QVTDLDVLDSLVPLSVCLNWQKVAAAVALSRRFAVISGGPGTGKTTTVTKLLSAMVEQSLSQGKIPTIKLVAPTGKAAAR
LTESIGKAIEQLPLAPEVKANIPTESSTLHRLLGAIPNRAEFRHNRRNPLHLDILVVDEASMVDLSMMYKLVDALPEHAR
LILLGDKDQLASVEAGAVLGDICSFNSTGYSTAQGNLIAEMTGFDAIAKPRQVKTGSANPPAIADSLCMLQKSYRFDARS
GIGQLAKAINNGSANQVDQVFAKGFADIENHPLSSDSYNLMLRTLVNEYGAYLNRMNVPLEELETQEARAKSVLDLFSQC
RLLCSIREGDFGVKGLNHRIERALAARRLVNPNNDELWYHGRPVMVTRNDHGLGLYNGDIGICMLEADVSSSSSIDDNSA
PRLKVYFELPDGSVKAVLPSRVPDHETAYAMTIHKSQGSEFDLTLMILPPDFSPILTRELIYTGITRAKKRLIMFSDTNV
LKRGIKVKTERVSGLGSRLTN

Sequences:

>Translated_741_residues
MTTTTTNTSTEAANTLKPVSLIPEQLMNVLKFLADKGSIRQLDYQFARFIAQQATSHSQEIGFLAGVVSHELGKGHICTQ
LIQQHKAGPEQTTDLAQLLGLYGETALQLNQKLLGIDWVTVLQSSNLVGTTNDCVKPLMFDGQRVYLQRYWNYEVVLAET
LNRLSKPVEFNIEQKKALTETLNQLFARSYHFLFNALTKAEANQQTSQVLRQQLVCDHLDIVDEQALDWGSIDQAIVQAK
QVTDLDVLDSLVPLSVCLNWQKVAAAVALSRRFAVISGGPGTGKTTTVTKLLSAMVEQSLSQGKIPTIKLVAPTGKAAAR
LTESIGKAIEQLPLAPEVKANIPTESSTLHRLLGAIPNRAEFRHNRRNPLHLDILVVDEASMVDLSMMYKLVDALPEHAR
LILLGDKDQLASVEAGAVLGDICSFNSTGYSTAQGNLIAEMTGFDAIAKPRQVKTGSANPPAIADSLCMLQKSYRFDARS
GIGQLAKAINNGSANQVDQVFAKGFADIENHPLSSDSYNLMLRTLVNEYGAYLNRMNVPLEELETQEARAKSVLDLFSQC
RLLCSIREGDFGVKGLNHRIERALAARRLVNPNNDELWYHGRPVMVTRNDHGLGLYNGDIGICMLEADVSSSSSIDDNSA
PRLKVYFELPDGSVKAVLPSRVPDHETAYAMTIHKSQGSEFDLTLMILPPDFSPILTRELIYTGITRAKKRLIMFSDTNV
LKRGIKVKTERVSGLGSRLTN
>Mature_740_residues
TTTTTNTSTEAANTLKPVSLIPEQLMNVLKFLADKGSIRQLDYQFARFIAQQATSHSQEIGFLAGVVSHELGKGHICTQL
IQQHKAGPEQTTDLAQLLGLYGETALQLNQKLLGIDWVTVLQSSNLVGTTNDCVKPLMFDGQRVYLQRYWNYEVVLAETL
NRLSKPVEFNIEQKKALTETLNQLFARSYHFLFNALTKAEANQQTSQVLRQQLVCDHLDIVDEQALDWGSIDQAIVQAKQ
VTDLDVLDSLVPLSVCLNWQKVAAAVALSRRFAVISGGPGTGKTTTVTKLLSAMVEQSLSQGKIPTIKLVAPTGKAAARL
TESIGKAIEQLPLAPEVKANIPTESSTLHRLLGAIPNRAEFRHNRRNPLHLDILVVDEASMVDLSMMYKLVDALPEHARL
ILLGDKDQLASVEAGAVLGDICSFNSTGYSTAQGNLIAEMTGFDAIAKPRQVKTGSANPPAIADSLCMLQKSYRFDARSG
IGQLAKAINNGSANQVDQVFAKGFADIENHPLSSDSYNLMLRTLVNEYGAYLNRMNVPLEELETQEARAKSVLDLFSQCR
LLCSIREGDFGVKGLNHRIERALAARRLVNPNNDELWYHGRPVMVTRNDHGLGLYNGDIGICMLEADVSSSSSIDDNSAP
RLKVYFELPDGSVKAVLPSRVPDHETAYAMTIHKSQGSEFDLTLMILPPDFSPILTRELIYTGITRAKKRLIMFSDTNVL
KRGIKVKTERVSGLGSRLTN

Specific function: Exhibits several catalytic activities, including ATP- dependent exonuclease, ATP-stimulated endonuclease, ATP-dependent unwinding and DNA-dependent ATPase activities. Strand cleavage occurs 5' to 3' during the unwinding of duplex DNA at CHI sequences, whi

COG id: COG0507

COG function: function code L; ATP-dependent exoDNAse (exonuclease V), alpha subunit - helicase superfamily I member

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the recD family [H]

Homologues:

Organism=Escherichia coli, GI1789182, Length=494, Percent_Identity=51.8218623481781, Blast_Score=476, Evalue=1e-135,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR007807
- InterPro:   IPR006344
- InterPro:   IPR000606 [H]

Pfam domain/function: PF05127 DUF699; PF01443 Viral_helicase1 [H]

EC number: =3.1.11.5 [H]

Molecular weight: Translated: 81481; Mature: 81350

Theoretical pI: Translated: 7.08; Mature: 7.08

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTTTTTNTSTEAANTLKPVSLIPEQLMNVLKFLADKGSIRQLDYQFARFIAQQATSHSQE
CCCCCCCCCHHHHHHCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCHHH
IGFLAGVVSHELGKGHICTQLIQQHKAGPEQTTDLAQLLGLYGETALQLNQKLLGIDWVT
HHHHHHHHHHHCCCCHHHHHHHHHHCCCCCHHHHHHHHHHHHCHHHHHHHHHHHCCHHHH
VLQSSNLVGTTNDCVKPLMFDGQRVYLQRYWNYEVVLAETLNRLSKPVEFNIEQKKALTE
HHCCCCCCCCCHHHHHHHHHCCCEEEEEHHCCEEEEHHHHHHHHCCCEEECCHHHHHHHH
TLNQLFARSYHFLFNALTKAEANQQTSQVLRQQLVCDHLDIVDEQALDWGSIDQAIVQAK
HHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHH
QVTDLDVLDSLVPLSVCLNWQKVAAAVALSRRFAVISGGPGTGKTTTVTKLLSAMVEQSL
HCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHCEEEEECCCCCCCHHHHHHHHHHHHHHHH
SQGKIPTIKLVAPTGKAAARLTESIGKAIEQLPLAPEVKANIPTESSTLHRLLGAIPNRA
HCCCCCEEEEECCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHCCCCHH
EFRHNRRNPLHLDILVVDEASMVDLSMMYKLVDALPEHARLILLGDKDQLASVEAGAVLG
HHHHCCCCCEEEEEEEECCCHHHHHHHHHHHHHHCCCCCEEEEECCCHHHHHHHHHHHHH
DICSFNSTGYSTAQGNLIAEMTGFDAIAKPRQVKTGSANPPAIADSLCMLQKSYRFDARS
HHHCCCCCCCCCCCCCEEEEECCCHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCHHC
GIGQLAKAINNGSANQVDQVFAKGFADIENHPLSSDSYNLMLRTLVNEYGAYLNRMNVPL
CHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCH
EELETQEARAKSVLDLFSQCRLLCSIREGDFGVKGLNHRIERALAARRLVNPNNDELWYH
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCEEEC
GRPVMVTRNDHGLGLYNGDIGICMLEADVSSSSSIDDNSAPRLKVYFELPDGSVKAVLPS
CEEEEEEECCCCCEEEECCEEEEEEEECCCCCCCCCCCCCCEEEEEEECCCCCEEEECCC
RVPDHETAYAMTIHKSQGSEFDLTLMILPPDFSPILTRELIYTGITRAKKRLIMFSDTNV
CCCCCCCEEEEEEECCCCCCEEEEEEEECCCCCHHHHHHHHHHHHHHHHCEEEEEECCHH
LKRGIKVKTERVSGLGSRLTN
HHCCCCEEHHHHHHHHHHCCC
>Mature Secondary Structure 
TTTTTNTSTEAANTLKPVSLIPEQLMNVLKFLADKGSIRQLDYQFARFIAQQATSHSQE
CCCCCCCCHHHHHHCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCHHH
IGFLAGVVSHELGKGHICTQLIQQHKAGPEQTTDLAQLLGLYGETALQLNQKLLGIDWVT
HHHHHHHHHHHCCCCHHHHHHHHHHCCCCCHHHHHHHHHHHHCHHHHHHHHHHHCCHHHH
VLQSSNLVGTTNDCVKPLMFDGQRVYLQRYWNYEVVLAETLNRLSKPVEFNIEQKKALTE
HHCCCCCCCCCHHHHHHHHHCCCEEEEEHHCCEEEEHHHHHHHHCCCEEECCHHHHHHHH
TLNQLFARSYHFLFNALTKAEANQQTSQVLRQQLVCDHLDIVDEQALDWGSIDQAIVQAK
HHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHH
QVTDLDVLDSLVPLSVCLNWQKVAAAVALSRRFAVISGGPGTGKTTTVTKLLSAMVEQSL
HCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHCEEEEECCCCCCCHHHHHHHHHHHHHHHH
SQGKIPTIKLVAPTGKAAARLTESIGKAIEQLPLAPEVKANIPTESSTLHRLLGAIPNRA
HCCCCCEEEEECCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHCCCCHH
EFRHNRRNPLHLDILVVDEASMVDLSMMYKLVDALPEHARLILLGDKDQLASVEAGAVLG
HHHHCCCCCEEEEEEEECCCHHHHHHHHHHHHHHCCCCCEEEEECCCHHHHHHHHHHHHH
DICSFNSTGYSTAQGNLIAEMTGFDAIAKPRQVKTGSANPPAIADSLCMLQKSYRFDARS
HHHCCCCCCCCCCCCCEEEEECCCHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCHHC
GIGQLAKAINNGSANQVDQVFAKGFADIENHPLSSDSYNLMLRTLVNEYGAYLNRMNVPL
CHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCH
EELETQEARAKSVLDLFSQCRLLCSIREGDFGVKGLNHRIERALAARRLVNPNNDELWYH
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCEEEC
GRPVMVTRNDHGLGLYNGDIGICMLEADVSSSSSIDDNSAPRLKVYFELPDGSVKAVLPS
CEEEEEEECCCCCEEEECCEEEEEEEECCCCCCCCCCCCCCEEEEEEECCCCCEEEECCC
RVPDHETAYAMTIHKSQGSEFDLTLMILPPDFSPILTRELIYTGITRAKKRLIMFSDTNV
CCCCCCCEEEEEEECCCCCCEEEEEEEECCCCCHHHHHHHHHHHHHHHHCEEEEEECCHH
LKRGIKVKTERVSGLGSRLTN
HHCCCCEEHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 3537961; 9278503; 3537960 [H]