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The map label for this gene is yjcE [H]

Identifier: 218708355

GI number: 218708355

Start: 301291

End: 302820

Strand: Reverse

Name: yjcE [H]

Synonym: VS_0314

Alternate gene names: 218708355

Gene position: 302820-301291 (Counterclockwise)

Preceding gene: 218708357

Following gene: 218708348

Centisome position: 9.18

GC content: 40.33

Gene sequence:

>1530_bases
GTGGTACCCATGCCACCATCAATCAGTAAAATTCGTTGCTTCAACAGAGCGTCAATCTTTTGCCTTACATTACTTCCCAC
GGTACAACCTCATTCCTTTAATTATCTCTCCATCCTACCACACATTAAAAAGGAGTCTAGACGTCTAAAATATGAAATTG
ATTACCAAGTCATGACAAAAAAATGTTTGCTATTTGAGCATGAGACAACGAAAATTCATATTCATACTTTGTTACATGTT
GGGATCCCAATGTCGGTCTATTACACCTTATGCTTCTTGTCCGCTGCAGCCATGCTTATTGCTTTCGTTAATACCAAAAT
TGGTAAAATGCAGACAACCATCGCCATCACAGCTGGCTCAATGATGCTATCTCTATTGATTATCATTGCGGGACAAAACA
ATTGGTTCCAATTGGCTGACATCGCTTCAGAAACCGTTGCCAGTATCAACTTTGAAGACTTCCTCCTAAAAGGAATACTG
GGATTCTTACTTTTTGCAGGTGGTTTGGGGATTAAGTTACCTAATCTAAAAGATCAGAAATGGGAAATAACGGTACTCGC
TCTTGGTGCTACACTGTTTTCGACATTCTTTATTGGCTTTGTACTTTATGGGTTTTGTCAATTTATCGGTATTCAATTTG
ACCTAATTTATTGCTTACTGTTTGGTTCTCTAATATCTCCAACCGATCCAATAGCTGTATTAGCAATAGTGAAGAAGCTC
GATGCTCCCAGACGAATCTCTACTCAAATCGAGGGAGAATCTCTATTCAACGATGGTTTTGGCCTAGTTATCTTCGTAAC
CCTATTTACCATTGCGTTCGGCACAGAAGCTCCGACTGTAGGTAGCGTGACCATGTTATTCGTCCAAGAGGCTATTGGCG
GTATCGTCTACGGATTTGTTCTAGGTTTGATATTCCACTATCTAATCAGCAACACCGATGACCACTCGATGGAGTTGCTA
TTAACCATCGGTATTCCTACAGCTGGTTATGCTTTTGCAGAGGTTCTGCATGTATCTGGACCATTAGCAATGGTGGTATC
TGGTATCATGATAGGCAACTGGACACGCTTCATCGGATTTTCTAAGGAAAGTGAGGATCACCTAGACCATTTCTGGGAAT
TAATAGATGAGTTCTTAAATGGCGTACTATTCTTATTGATTGGTATGTCTATGCTGCTATTCAAGTTCCACCAAGAAGAT
TGGATTTTGATGGCGTTCGCAGTCCCTCTAGTATTGAGTGCACGCTATCTAAGTGTTTTCTTGTCTTATATTGGATTTAA
ACGCTTTAGAACTTACAACCCATGGTCGACTAAGGTTCTAACTTGGGGTGGTCTACGCGGAGGCTTAGCTCTAGCTATGG
CACTTTCAATCCCTTCAGGTATCTGGGTGATTGAAGACAAAGCAATAGATGTTAAAGAGATAATCCTCGTTATGACCTAT
GCTGTTGTTGTGTTCTCTATTCTGGTTCAAGGATCAACAATCACTCCAATGATAGAAAAAGCGAAACAAGCTGAGAAAGA
ATTGGATTAA

Upstream 100 bases:

>100_bases
CGTAAGTACCAAAAGGTCATTGTTACCTTTTAAGTCACTATGCCAATCAGCAAATCGCTCACCGCGATAGTCTTGCTCTT
CCAATTTATAATCCTGAATC

Downstream 100 bases:

>100_bases
TACCTAAAAATATAAACGAAGGTCGCTTAGTAGAAGCGGCCTTTTTTGTACCTGTGTCCATCAACAAGCACGCCTCTCTA
GCCTACAAGTTGCTCCCTTA

Product: putative Na+/H+ antiporter

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 509; Mature: 509

Protein sequence:

>509_residues
MVPMPPSISKIRCFNRASIFCLTLLPTVQPHSFNYLSILPHIKKESRRLKYEIDYQVMTKKCLLFEHETTKIHIHTLLHV
GIPMSVYYTLCFLSAAAMLIAFVNTKIGKMQTTIAITAGSMMLSLLIIIAGQNNWFQLADIASETVASINFEDFLLKGIL
GFLLFAGGLGIKLPNLKDQKWEITVLALGATLFSTFFIGFVLYGFCQFIGIQFDLIYCLLFGSLISPTDPIAVLAIVKKL
DAPRRISTQIEGESLFNDGFGLVIFVTLFTIAFGTEAPTVGSVTMLFVQEAIGGIVYGFVLGLIFHYLISNTDDHSMELL
LTIGIPTAGYAFAEVLHVSGPLAMVVSGIMIGNWTRFIGFSKESEDHLDHFWELIDEFLNGVLFLLIGMSMLLFKFHQED
WILMAFAVPLVLSARYLSVFLSYIGFKRFRTYNPWSTKVLTWGGLRGGLALAMALSIPSGIWVIEDKAIDVKEIILVMTY
AVVVFSILVQGSTITPMIEKAKQAEKELD

Sequences:

>Translated_509_residues
MVPMPPSISKIRCFNRASIFCLTLLPTVQPHSFNYLSILPHIKKESRRLKYEIDYQVMTKKCLLFEHETTKIHIHTLLHV
GIPMSVYYTLCFLSAAAMLIAFVNTKIGKMQTTIAITAGSMMLSLLIIIAGQNNWFQLADIASETVASINFEDFLLKGIL
GFLLFAGGLGIKLPNLKDQKWEITVLALGATLFSTFFIGFVLYGFCQFIGIQFDLIYCLLFGSLISPTDPIAVLAIVKKL
DAPRRISTQIEGESLFNDGFGLVIFVTLFTIAFGTEAPTVGSVTMLFVQEAIGGIVYGFVLGLIFHYLISNTDDHSMELL
LTIGIPTAGYAFAEVLHVSGPLAMVVSGIMIGNWTRFIGFSKESEDHLDHFWELIDEFLNGVLFLLIGMSMLLFKFHQED
WILMAFAVPLVLSARYLSVFLSYIGFKRFRTYNPWSTKVLTWGGLRGGLALAMALSIPSGIWVIEDKAIDVKEIILVMTY
AVVVFSILVQGSTITPMIEKAKQAEKELD
>Mature_509_residues
MVPMPPSISKIRCFNRASIFCLTLLPTVQPHSFNYLSILPHIKKESRRLKYEIDYQVMTKKCLLFEHETTKIHIHTLLHV
GIPMSVYYTLCFLSAAAMLIAFVNTKIGKMQTTIAITAGSMMLSLLIIIAGQNNWFQLADIASETVASINFEDFLLKGIL
GFLLFAGGLGIKLPNLKDQKWEITVLALGATLFSTFFIGFVLYGFCQFIGIQFDLIYCLLFGSLISPTDPIAVLAIVKKL
DAPRRISTQIEGESLFNDGFGLVIFVTLFTIAFGTEAPTVGSVTMLFVQEAIGGIVYGFVLGLIFHYLISNTDDHSMELL
LTIGIPTAGYAFAEVLHVSGPLAMVVSGIMIGNWTRFIGFSKESEDHLDHFWELIDEFLNGVLFLLIGMSMLLFKFHQED
WILMAFAVPLVLSARYLSVFLSYIGFKRFRTYNPWSTKVLTWGGLRGGLALAMALSIPSGIWVIEDKAIDVKEIILVMTY
AVVVFSILVQGSTITPMIEKAKQAEKELD

Specific function: Unknown

COG id: COG0025

COG function: function code P; NhaP-type Na+/H+ and K+/H+ antiporters

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family [H]

Homologues:

Organism=Homo sapiens, GI148727259, Length=324, Percent_Identity=26.8518518518519, Blast_Score=107, Evalue=2e-23,
Organism=Homo sapiens, GI15529998, Length=333, Percent_Identity=26.7267267267267, Blast_Score=105, Evalue=1e-22,
Organism=Homo sapiens, GI27777632, Length=345, Percent_Identity=24.9275362318841, Blast_Score=88, Evalue=2e-17,
Organism=Homo sapiens, GI27734935, Length=355, Percent_Identity=23.943661971831, Blast_Score=86, Evalue=7e-17,
Organism=Homo sapiens, GI41872703, Length=441, Percent_Identity=23.8095238095238, Blast_Score=84, Evalue=4e-16,
Organism=Homo sapiens, GI294997330, Length=414, Percent_Identity=22.2222222222222, Blast_Score=80, Evalue=4e-15,
Organism=Homo sapiens, GI110227626, Length=414, Percent_Identity=22.2222222222222, Blast_Score=79, Evalue=8e-15,
Organism=Homo sapiens, GI5454070, Length=354, Percent_Identity=22.8813559322034, Blast_Score=78, Evalue=2e-14,
Organism=Homo sapiens, GI14211919, Length=408, Percent_Identity=24.7549019607843, Blast_Score=77, Evalue=5e-14,
Organism=Homo sapiens, GI194239733, Length=357, Percent_Identity=24.9299719887955, Blast_Score=75, Evalue=1e-13,
Organism=Homo sapiens, GI4759144, Length=341, Percent_Identity=27.2727272727273, Blast_Score=74, Evalue=3e-13,
Organism=Escherichia coli, GI1790501, Length=339, Percent_Identity=26.5486725663717, Blast_Score=93, Evalue=3e-20,
Organism=Caenorhabditis elegans, GI71999819, Length=400, Percent_Identity=24, Blast_Score=101, Evalue=1e-21,
Organism=Caenorhabditis elegans, GI71999817, Length=400, Percent_Identity=24, Blast_Score=101, Evalue=1e-21,
Organism=Caenorhabditis elegans, GI71999821, Length=400, Percent_Identity=24, Blast_Score=100, Evalue=1e-21,
Organism=Caenorhabditis elegans, GI25150332, Length=325, Percent_Identity=24.3076923076923, Blast_Score=97, Evalue=2e-20,
Organism=Caenorhabditis elegans, GI71987535, Length=340, Percent_Identity=24.4117647058824, Blast_Score=94, Evalue=1e-19,
Organism=Caenorhabditis elegans, GI71987537, Length=340, Percent_Identity=24.4117647058824, Blast_Score=94, Evalue=1e-19,
Organism=Caenorhabditis elegans, GI71990924, Length=365, Percent_Identity=23.013698630137, Blast_Score=86, Evalue=4e-17,
Organism=Caenorhabditis elegans, GI71990932, Length=365, Percent_Identity=23.013698630137, Blast_Score=85, Evalue=1e-16,
Organism=Caenorhabditis elegans, GI71992107, Length=345, Percent_Identity=24.0579710144928, Blast_Score=85, Evalue=1e-16,
Organism=Caenorhabditis elegans, GI71992101, Length=300, Percent_Identity=24.3333333333333, Blast_Score=85, Evalue=1e-16,
Organism=Caenorhabditis elegans, GI71980847, Length=358, Percent_Identity=23.7430167597765, Blast_Score=83, Evalue=4e-16,
Organism=Caenorhabditis elegans, GI25147678, Length=312, Percent_Identity=24.6794871794872, Blast_Score=79, Evalue=7e-15,
Organism=Caenorhabditis elegans, GI71987559, Length=338, Percent_Identity=23.0769230769231, Blast_Score=75, Evalue=7e-14,
Organism=Caenorhabditis elegans, GI71987545, Length=338, Percent_Identity=23.0769230769231, Blast_Score=75, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI71993590, Length=337, Percent_Identity=26.4094955489614, Blast_Score=70, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI71993582, Length=337, Percent_Identity=26.1127596439169, Blast_Score=70, Evalue=2e-12,
Organism=Saccharomyces cerevisiae, GI6320663, Length=323, Percent_Identity=23.5294117647059, Blast_Score=69, Evalue=1e-12,
Organism=Drosophila melanogaster, GI221510734, Length=356, Percent_Identity=26.685393258427, Blast_Score=95, Evalue=9e-20,
Organism=Drosophila melanogaster, GI221510738, Length=356, Percent_Identity=26.685393258427, Blast_Score=94, Evalue=2e-19,
Organism=Drosophila melanogaster, GI281360447, Length=439, Percent_Identity=22.7790432801822, Blast_Score=88, Evalue=1e-17,
Organism=Drosophila melanogaster, GI221510736, Length=356, Percent_Identity=26.685393258427, Blast_Score=88, Evalue=1e-17,
Organism=Drosophila melanogaster, GI221510732, Length=356, Percent_Identity=26.685393258427, Blast_Score=88, Evalue=1e-17,
Organism=Drosophila melanogaster, GI24585580, Length=351, Percent_Identity=26.7806267806268, Blast_Score=87, Evalue=2e-17,
Organism=Drosophila melanogaster, GI24585578, Length=351, Percent_Identity=26.7806267806268, Blast_Score=87, Evalue=2e-17,
Organism=Drosophila melanogaster, GI221510740, Length=351, Percent_Identity=26.7806267806268, Blast_Score=87, Evalue=2e-17,
Organism=Drosophila melanogaster, GI281364513, Length=353, Percent_Identity=25.2124645892351, Blast_Score=83, Evalue=4e-16,
Organism=Drosophila melanogaster, GI221473212, Length=353, Percent_Identity=25.2124645892351, Blast_Score=83, Evalue=4e-16,
Organism=Drosophila melanogaster, GI221473222, Length=353, Percent_Identity=25.2124645892351, Blast_Score=82, Evalue=6e-16,
Organism=Drosophila melanogaster, GI221473215, Length=353, Percent_Identity=25.2124645892351, Blast_Score=82, Evalue=7e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006153
- InterPro:   IPR018422
- InterPro:   IPR004705 [H]

Pfam domain/function: PF00999 Na_H_Exchanger [H]

EC number: NA

Molecular weight: Translated: 56679; Mature: 56679

Theoretical pI: Translated: 6.65; Mature: 6.65

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVPMPPSISKIRCFNRASIFCLTLLPTVQPHSFNYLSILPHIKKESRRLKYEIDYQVMTK
CCCCCCCHHHHEECCCCCEEEEECCCCCCCCCCCHHHHHHHHHHCCCCEEEEECHHHHHH
KCLLFEHETTKIHIHTLLHVGIPMSVYYTLCFLSAAAMLIAFVNTKIGKMQTTIAITAGS
HHHEEECCCCEEEEEEHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEEEHHH
MMLSLLIIIAGQNNWFQLADIASETVASINFEDFLLKGILGFLLFAGGLGIKLPNLKDQK
HHHHHHHHEECCCCCEEHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCCEECCCCCCCC
WEITVLALGATLFSTFFIGFVLYGFCQFIGIQFDLIYCLLFGSLISPTDPIAVLAIVKKL
EEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHC
DAPRRISTQIEGESLFNDGFGLVIFVTLFTIAFGTEAPTVGSVTMLFVQEAIGGIVYGFV
CCCCHHHCCCCCCHHHCCCCHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHH
LGLIFHYLISNTDDHSMELLLTIGIPTAGYAFAEVLHVSGPLAMVVSGIMIGNWTRFIGF
HHHHHHHHHCCCCCCCEEEEEEECCCCCHHHHHHHHHCCCCHHHHHHHHHHCCHHHHCCC
SKESEDHLDHFWELIDEFLNGVLFLLIGMSMLLFKFHQEDWILMAFAVPLVLSARYLSVF
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHH
LSYIGFKRFRTYNPWSTKVLTWGGLRGGLALAMALSIPSGIWVIEDKAIDVKEIILVMTY
HHHHHHHHHCCCCCCCCCEEEECCCHHHHHHHHHHHCCCCEEEEECCCCCHHHHHHHHHH
AVVVFSILVQGSTITPMIEKAKQAEKELD
HHHHHHHHHCCCCCCHHHHHHHHHHHCCC
>Mature Secondary Structure
MVPMPPSISKIRCFNRASIFCLTLLPTVQPHSFNYLSILPHIKKESRRLKYEIDYQVMTK
CCCCCCCHHHHEECCCCCEEEEECCCCCCCCCCCHHHHHHHHHHCCCCEEEEECHHHHHH
KCLLFEHETTKIHIHTLLHVGIPMSVYYTLCFLSAAAMLIAFVNTKIGKMQTTIAITAGS
HHHEEECCCCEEEEEEHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEEEHHH
MMLSLLIIIAGQNNWFQLADIASETVASINFEDFLLKGILGFLLFAGGLGIKLPNLKDQK
HHHHHHHHEECCCCCEEHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCCEECCCCCCCC
WEITVLALGATLFSTFFIGFVLYGFCQFIGIQFDLIYCLLFGSLISPTDPIAVLAIVKKL
EEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHC
DAPRRISTQIEGESLFNDGFGLVIFVTLFTIAFGTEAPTVGSVTMLFVQEAIGGIVYGFV
CCCCHHHCCCCCCHHHCCCCHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHH
LGLIFHYLISNTDDHSMELLLTIGIPTAGYAFAEVLHVSGPLAMVVSGIMIGNWTRFIGF
HHHHHHHHHCCCCCCCEEEEEEECCCCCHHHHHHHHHCCCCHHHHHHHHHHCCHHHHCCC
SKESEDHLDHFWELIDEFLNGVLFLLIGMSMLLFKFHQEDWILMAFAVPLVLSARYLSVF
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHH
LSYIGFKRFRTYNPWSTKVLTWGGLRGGLALAMALSIPSGIWVIEDKAIDVKEIILVMTY
HHHHHHHHHCCCCCCCCCEEEECCCHHHHHHHHHHHCCCCEEEEECCCCCHHHHHHHHHH
AVVVFSILVQGSTITPMIEKAKQAEKELD
HHHHHHHHHCCCCCCHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8265357; 9278503 [H]