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The map label for this gene is ipaB [H]

Identifier: 218702498

GI number: 218702498

Start: 4420346

End: 4422127

Strand: Direct

Name: ipaB [H]

Synonym: ECIAI39_4254

Alternate gene names: 218702498

Gene position: 4420346-4422127 (Clockwise)

Preceding gene: 218702497

Following gene: 218702499

Centisome position: 86.13

GC content: 40.85

Gene sequence:

>1782_bases
ATGTCGGCACCGATTACGGGACAAACGATCACGTTTGAACAAATCAGTGAAACATTGCGTACACAGTATAGCGATGCGGA
AAAAAGACTGCAGGACAGCAGCAAAACGCAAGTTGATCCCATGCGGCTTAATAAAAACCCGAAATCCCTTGATAACGATA
TTCGCGCTCGTCTTGAAAACAAACCGATGCTTGCTCCGCCTGAAATACAGGTTTCAGATTCAGACAACGCCACTACAGCA
AAGACGAATGATGCCCGCCTGACAATGATTTTGGGTAATTTAACAGGCATTGCCGATCAGGATATTACAAAACGATTGCA
TAATAACCTTGACAGCACCCTGCTTCGACACGAAATGGCACATAATAAGTTTCGTGAATTAAGTGACGCTTACTCCTCAT
CATTAGATGATGCGCAAAAAGCCGACGATATCATGCATCAGGCCAATAATAATTACAATGCGGTCGATAAAAAGGTGCAA
TCGCTGGAGAAAAAAGTCAACACATTGAATCAAGAGCTGTCACAACTGCAACCTAGCGATCCGCAATATAATAAAGTACT
GACGCAAAAAAATGCGGCTGAAAAAACACTCACGCTGTCATTACAAAAAAAATCGTTAGCTGAGCAATCGTTAAATACAG
CCATTATGGATGCTGATGCTGCGATCGGCCAAAGTATGGAAATTTTTGACGAAATTCAACAGCAAGAACAGATTAATAAC
TTCACCACCAATATTTGCCTGACACAGGAAAACCAGAAAAATAGAAACGCGACAGCCACATTTATCCTTTTGATTACTTC
AGTAATGGAAGTTATTGGTGATACCAATTGCGACTCTATTAAAAATCAATCTGAGGTAATGAAAGAGATTAACCATGTCA
GGGAAAATAAACTCAATGAAACAGCGCGTAAATATACTACCACGACTAAAGTTTTAAAAATCGTTAATGAGTGTGTAACT
GTAGTTACCTTTGCCGTAAGCGCAGTCTTAATTGTTGTTGGTCTTCTTGCTGCAGTTCCAAGTGGTGGTTCAAGTATTGC
GGGTGCATTGGCACTTATTGGAGGAATAGCGGGCGCAGTAGTATTAGGTGTAGATATCACTTGTCAAATCGCTCTGGGCA
CCACGGCTACCGGCTGGATTTTAGGGAAAGTTGTTGAAGGTCTTTCGGCTGCGATTAAAACAGTTGATCCCACTCTGCTC
GCAATCACCGCGCTTCTGGACGTTATTGGTGTCGATCAAAATACGATTGAACTGGTTAAAAGTATTTACGCAAGTGCAGC
CGCTTCTATTGTCATGGCGACAGTAATGATTGGTGCAGCTGTAATATGTTCTGTAGCAATAGGGGCCGTTGTTTCTGCAT
TATCAAAAACAGCCGCCGAAGAAGTCACCAAAGAAATAACAAGCACTATAAAATCAACCATTGAATCAATTATTAATTCA
GTTTCAAAAAATATTATAAAGGTATTAGACAGCGTATGCAGCGTGCTACAAACATCAGCCGTAGTGTTGAAGTTGATTGC
CAAAATAAGTAATGGCCTGGAGAAAATAGGCTTACTCATCTGTGCAATAGCAACATCGACGATGAATTGTTTTGTTGCTG
GAAACTCTGCCGACATGGCAATTTTACAACAGGACATGAGTAATCTATCAAAAACGCGTGAACAAATGCTTTCAGTATTG
CAAAGGGTGGATAAAACCGTCGAACAAGAGGTAAGCCAGATGGTAAGAGTATTACAACACCGAACTGAAGCCTTAAAATT
TGCTTCCCATTCTATCGTATAA

Upstream 100 bases:

>100_bases
TTTCCCGTTGATGCCATTTTAGATGGGAATAAACATCTGCCATGAGTTAAATAAAAAAGAATTAATTACACCCGATGATA
GCTTAAAAAGGAGGTGAATT

Downstream 100 bases:

>100_bases
GAGGGTTTTAACATGGCCACCTATGAAATTAAAAATGCGACCAGCACATCTAATATTAACAGTCTTGATAAAACAATCTT
TGATAGAGATTATAGTAAAA

Product: hypothetical protein

Products: NA

Alternate protein names: 62 kDa antigen [H]

Number of amino acids: Translated: 593; Mature: 592

Protein sequence:

>593_residues
MSAPITGQTITFEQISETLRTQYSDAEKRLQDSSKTQVDPMRLNKNPKSLDNDIRARLENKPMLAPPEIQVSDSDNATTA
KTNDARLTMILGNLTGIADQDITKRLHNNLDSTLLRHEMAHNKFRELSDAYSSSLDDAQKADDIMHQANNNYNAVDKKVQ
SLEKKVNTLNQELSQLQPSDPQYNKVLTQKNAAEKTLTLSLQKKSLAEQSLNTAIMDADAAIGQSMEIFDEIQQQEQINN
FTTNICLTQENQKNRNATATFILLITSVMEVIGDTNCDSIKNQSEVMKEINHVRENKLNETARKYTTTTKVLKIVNECVT
VVTFAVSAVLIVVGLLAAVPSGGSSIAGALALIGGIAGAVVLGVDITCQIALGTTATGWILGKVVEGLSAAIKTVDPTLL
AITALLDVIGVDQNTIELVKSIYASAAASIVMATVMIGAAVICSVAIGAVVSALSKTAAEEVTKEITSTIKSTIESIINS
VSKNIIKVLDSVCSVLQTSAVVLKLIAKISNGLEKIGLLICAIATSTMNCFVAGNSADMAILQQDMSNLSKTREQMLSVL
QRVDKTVEQEVSQMVRVLQHRTEALKFASHSIV

Sequences:

>Translated_593_residues
MSAPITGQTITFEQISETLRTQYSDAEKRLQDSSKTQVDPMRLNKNPKSLDNDIRARLENKPMLAPPEIQVSDSDNATTA
KTNDARLTMILGNLTGIADQDITKRLHNNLDSTLLRHEMAHNKFRELSDAYSSSLDDAQKADDIMHQANNNYNAVDKKVQ
SLEKKVNTLNQELSQLQPSDPQYNKVLTQKNAAEKTLTLSLQKKSLAEQSLNTAIMDADAAIGQSMEIFDEIQQQEQINN
FTTNICLTQENQKNRNATATFILLITSVMEVIGDTNCDSIKNQSEVMKEINHVRENKLNETARKYTTTTKVLKIVNECVT
VVTFAVSAVLIVVGLLAAVPSGGSSIAGALALIGGIAGAVVLGVDITCQIALGTTATGWILGKVVEGLSAAIKTVDPTLL
AITALLDVIGVDQNTIELVKSIYASAAASIVMATVMIGAAVICSVAIGAVVSALSKTAAEEVTKEITSTIKSTIESIINS
VSKNIIKVLDSVCSVLQTSAVVLKLIAKISNGLEKIGLLICAIATSTMNCFVAGNSADMAILQQDMSNLSKTREQMLSVL
QRVDKTVEQEVSQMVRVLQHRTEALKFASHSIV
>Mature_592_residues
SAPITGQTITFEQISETLRTQYSDAEKRLQDSSKTQVDPMRLNKNPKSLDNDIRARLENKPMLAPPEIQVSDSDNATTAK
TNDARLTMILGNLTGIADQDITKRLHNNLDSTLLRHEMAHNKFRELSDAYSSSLDDAQKADDIMHQANNNYNAVDKKVQS
LEKKVNTLNQELSQLQPSDPQYNKVLTQKNAAEKTLTLSLQKKSLAEQSLNTAIMDADAAIGQSMEIFDEIQQQEQINNF
TTNICLTQENQKNRNATATFILLITSVMEVIGDTNCDSIKNQSEVMKEINHVRENKLNETARKYTTTTKVLKIVNECVTV
VTFAVSAVLIVVGLLAAVPSGGSSIAGALALIGGIAGAVVLGVDITCQIALGTTATGWILGKVVEGLSAAIKTVDPTLLA
ITALLDVIGVDQNTIELVKSIYASAAASIVMATVMIGAAVICSVAIGAVVSALSKTAAEEVTKEITSTIKSTIESIINSV
SKNIIKVLDSVCSVLQTSAVVLKLIAKISNGLEKIGLLICAIATSTMNCFVAGNSADMAILQQDMSNLSKTREQMLSVLQ
RVDKTVEQEVSQMVRVLQHRTEALKFASHSIV

Specific function: Associated with the entry of the bacteria into colonic epithelial cells [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Secreted. Host cell membrane; Multi-pass membrane protein (Potential). Note=Secreted through a type-III system [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006972
- InterPro:   IPR003895 [H]

Pfam domain/function: PF04888 SseC [H]

EC number: NA

Molecular weight: Translated: 63932; Mature: 63801

Theoretical pI: Translated: 5.56; Mature: 5.56

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSAPITGQTITFEQISETLRTQYSDAEKRLQDSSKTQVDPMRLNKNPKSLDNDIRARLEN
CCCCCCCCEEEHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHCCCCCHHHHHHHHHHHCC
KPMLAPPEIQVSDSDNATTAKTNDARLTMILGNLTGIADQDITKRLHNNLDSTLLRHEMA
CCCCCCCCEEECCCCCCCCCCCCCCEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHH
HNKFRELSDAYSSSLDDAQKADDIMHQANNNYNAVDKKVQSLEKKVNTLNQELSQLQPSD
HHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCC
PQYNKVLTQKNAAEKTLTLSLQKKSLAEQSLNTAIMDADAAIGQSMEIFDEIQQQEQINN
CHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHCCHHHHHHHHHHHHHHHH
FTTNICLTQENQKNRNATATFILLITSVMEVIGDTNCDSIKNQSEVMKEINHVRENKLNE
HHHHEEEECCCCCCCCHHHHHHHHHHHHHHHHCCCCCHHHCCHHHHHHHHHHHHHHHHHH
TARKYTTTTKVLKIVNECVTVVTFAVSAVLIVVGLLAAVPSGGSSIAGALALIGGIAGAV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHH
VLGVDITCQIALGTTATGWILGKVVEGLSAAIKTVDPTLLAITALLDVIGVDQNTIELVK
HHCCCEEEEEEECCCHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCHHHHHHHH
SIYASAAASIVMATVMIGAAVICSVAIGAVVSALSKTAAEEVTKEITSTIKSTIESIINS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VSKNIIKVLDSVCSVLQTSAVVLKLIAKISNGLEKIGLLICAIATSTMNCFVAGNSADMA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCEEEEECCCHHHH
ILQQDMSNLSKTREQMLSVLQRVDKTVEQEVSQMVRVLQHRTEALKFASHSIV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
SAPITGQTITFEQISETLRTQYSDAEKRLQDSSKTQVDPMRLNKNPKSLDNDIRARLEN
CCCCCCCEEEHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHCCCCCHHHHHHHHHHHCC
KPMLAPPEIQVSDSDNATTAKTNDARLTMILGNLTGIADQDITKRLHNNLDSTLLRHEMA
CCCCCCCCEEECCCCCCCCCCCCCCEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHH
HNKFRELSDAYSSSLDDAQKADDIMHQANNNYNAVDKKVQSLEKKVNTLNQELSQLQPSD
HHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCC
PQYNKVLTQKNAAEKTLTLSLQKKSLAEQSLNTAIMDADAAIGQSMEIFDEIQQQEQINN
CHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHCCHHHHHHHHHHHHHHHH
FTTNICLTQENQKNRNATATFILLITSVMEVIGDTNCDSIKNQSEVMKEINHVRENKLNE
HHHHEEEECCCCCCCCHHHHHHHHHHHHHHHHCCCCCHHHCCHHHHHHHHHHHHHHHHHH
TARKYTTTTKVLKIVNECVTVVTFAVSAVLIVVGLLAAVPSGGSSIAGALALIGGIAGAV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHH
VLGVDITCQIALGTTATGWILGKVVEGLSAAIKTVDPTLLAITALLDVIGVDQNTIELVK
HHCCCEEEEEEECCCHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCHHHHHHHH
SIYASAAASIVMATVMIGAAVICSVAIGAVVSALSKTAAEEVTKEITSTIKSTIESIINS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VSKNIIKVLDSVCSVLQTSAVVLKLIAKISNGLEKIGLLICAIATSTMNCFVAGNSADMA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCEEEEECCCHHHH
ILQQDMSNLSKTREQMLSVLQRVDKTVEQEVSQMVRVLQHRTEALKFASHSIV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 1766387 [H]