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The map label for this gene is aapM

Identifier: 218702042

GI number: 218702042

Start: 3935862

End: 3936965

Strand: Direct

Name: aapM

Synonym: ECIAI39_3771

Alternate gene names: 218702042

Gene position: 3935862-3936965 (Clockwise)

Preceding gene: 218702041

Following gene: 218702043

Centisome position: 76.69

GC content: 52.45

Gene sequence:

>1104_bases
ATGACAAAAGTATTGCTGTCTCATCCCCCGCGCCCGGCGAGCCATAACTCAAGCCGCGCGATGGTGTGGGTGCGAAAAAA
TCTGTTCTCCAGCTGGAGCAATAGCCTGCTGACTATTGGCTGCATATGGTTGATGTGGGAACTGATCCCACCGTTGCTGA
ACTGGGCATTTTTGCAGGCTAACTGGGTTGGCTCAACGCGTGCCGACTGCACAAAAGCCGGTGCCTGTTGGGTCTTCATC
CACGAACGATTTGGTCAGTTTATGTATGGGCTTTACCCACACGACCAACGCTGGCGAATTAACCTCGCATTACTGATTGG
GCTTGTGTCGATCGCACCAATGTTCTGGAAAATACTCCCGCATCGCGGTCGCTATATTGCGGTATGGGCGGTGATTTACC
CACTGATTGTCTGGTGGCTGATGTATGGCGGGTTTCTTGGTCTTGAGCGGGTTGAAACCCGGCAATGGGGCGGGCTGACG
CTAACTTTAATTATTGCATCAGTTGGGATTGCGGGGGCGCTGCCGTGGGGGATCTTACTGGCGTTAGGTCGCCGCTCCCA
TATGCCGATTGTGCGTATCTTATCGGTCATTTTTATCGAGTTCTGGCGCGGTGTACCGCTGATTACCGTTCTGTTTATGT
CTTCGGTCATGCTGCCGTTGTTTATGGCAGAAGGCACCAGTATCGACAAATTGATCCGCGCGCTGGTTGGCGTGATCCTG
TTTCAGTCAGCATATGTTGCGGAAGTCGTGCGAGGCGGATTACAGGCGCTGCCTAAAGGGCAATATGAAGCGGCAGAGTC
GCTGGCGTTGGGTTACTGGAAAACCCAGGGGCTGGTTATTCTGCCACAGGCGTTGAAGCTGGTGATTCCTGGGCTGGTAA
ATACCATCATCGCACTCTTCAAAGATACCAGCCTGGTGATCATCATCGGGTTGTTCGATCTTTTCAGTAGCGTTCAGCAA
GCAACCGTTGATCCCGCCTGGTTGGGTATGTCGACGGAAGGGTATGTTTTCGCCGCACTGATCTACTGGATCTTCTGTTT
CAGCATGTCACGTTATAGCCAACATCTGGAAAAACGTTTTAACACCGGGCGTACACCGCATTGA

Upstream 100 bases:

>100_bases
CATGACCATGTCGGTCTATCTGATTATCAGCCTGACTATCTCGCTGCTGATGAATATCTATAACCGCCGCATCGCGATCG
TTGAACGCTAAGGAGTCATG

Downstream 100 bases:

>100_bases
GGACACTATGAGCCAAATTTTACTGCAACCTGCTAACGCGATGATTACGCTGGAAAACGTCAATAAATGGTATGGGCAAT
TCCATGTTTTGAAAAATATA

Product: amino-acid ABC transporter membrane protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 367; Mature: 366

Protein sequence:

>367_residues
MTKVLLSHPPRPASHNSSRAMVWVRKNLFSSWSNSLLTIGCIWLMWELIPPLLNWAFLQANWVGSTRADCTKAGACWVFI
HERFGQFMYGLYPHDQRWRINLALLIGLVSIAPMFWKILPHRGRYIAVWAVIYPLIVWWLMYGGFLGLERVETRQWGGLT
LTLIIASVGIAGALPWGILLALGRRSHMPIVRILSVIFIEFWRGVPLITVLFMSSVMLPLFMAEGTSIDKLIRALVGVIL
FQSAYVAEVVRGGLQALPKGQYEAAESLALGYWKTQGLVILPQALKLVIPGLVNTIIALFKDTSLVIIIGLFDLFSSVQQ
ATVDPAWLGMSTEGYVFAALIYWIFCFSMSRYSQHLEKRFNTGRTPH

Sequences:

>Translated_367_residues
MTKVLLSHPPRPASHNSSRAMVWVRKNLFSSWSNSLLTIGCIWLMWELIPPLLNWAFLQANWVGSTRADCTKAGACWVFI
HERFGQFMYGLYPHDQRWRINLALLIGLVSIAPMFWKILPHRGRYIAVWAVIYPLIVWWLMYGGFLGLERVETRQWGGLT
LTLIIASVGIAGALPWGILLALGRRSHMPIVRILSVIFIEFWRGVPLITVLFMSSVMLPLFMAEGTSIDKLIRALVGVIL
FQSAYVAEVVRGGLQALPKGQYEAAESLALGYWKTQGLVILPQALKLVIPGLVNTIIALFKDTSLVIIIGLFDLFSSVQQ
ATVDPAWLGMSTEGYVFAALIYWIFCFSMSRYSQHLEKRFNTGRTPH
>Mature_366_residues
TKVLLSHPPRPASHNSSRAMVWVRKNLFSSWSNSLLTIGCIWLMWELIPPLLNWAFLQANWVGSTRADCTKAGACWVFIH
ERFGQFMYGLYPHDQRWRINLALLIGLVSIAPMFWKILPHRGRYIAVWAVIYPLIVWWLMYGGFLGLERVETRQWGGLTL
TLIIASVGIAGALPWGILLALGRRSHMPIVRILSVIFIEFWRGVPLITVLFMSSVMLPLFMAEGTSIDKLIRALVGVILF
QSAYVAEVVRGGLQALPKGQYEAAESLALGYWKTQGLVILPQALKLVIPGLVNTIIALFKDTSLVIIIGLFDLFSSVQQA
TVDPAWLGMSTEGYVFAALIYWIFCFSMSRYSQHLEKRFNTGRTPH

Specific function: Probably part of the binding-protein-dependent transport system ydhWXYZ for an amino acid; probably responsible for the translocation of the substrate across the membrane [H]

COG id: COG0765

COG function: function code E; ABC-type amino acid transport system, permease component

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transmembrane type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI87082239, Length=367, Percent_Identity=98.9100817438692, Blast_Score=732, Evalue=0.0,
Organism=Escherichia coli, GI1788226, Length=212, Percent_Identity=38.6792452830189, Blast_Score=112, Evalue=3e-26,
Organism=Escherichia coli, GI1786873, Length=208, Percent_Identity=31.25, Blast_Score=109, Evalue=3e-25,
Organism=Escherichia coli, GI1787030, Length=204, Percent_Identity=32.3529411764706, Blast_Score=87, Evalue=1e-18,
Organism=Escherichia coli, GI1788645, Length=212, Percent_Identity=27.8301886792453, Blast_Score=72, Evalue=8e-14,
Organism=Escherichia coli, GI48994930, Length=120, Percent_Identity=33.3333333333333, Blast_Score=70, Evalue=2e-13,
Organism=Escherichia coli, GI1786874, Length=169, Percent_Identity=25.4437869822485, Blast_Score=67, Evalue=2e-12,
Organism=Escherichia coli, GI1787087, Length=184, Percent_Identity=29.3478260869565, Blast_Score=65, Evalue=8e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010065
- InterPro:   IPR000515 [H]

Pfam domain/function: PF00528 BPD_transp_1 [H]

EC number: NA

Molecular weight: Translated: 41439; Mature: 41308

Theoretical pI: Translated: 10.19; Mature: 10.19

Prosite motif: PS50928 ABC_TM1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTKVLLSHPPRPASHNSSRAMVWVRKNLFSSWSNSLLTIGCIWLMWELIPPLLNWAFLQA
CCCCCCCCCCCCCCCCCCCEEEHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHEE
NWVGSTRADCTKAGACWVFIHERFGQFMYGLYPHDQRWRINLALLIGLVSIAPMFWKILP
CCCCCCCCHHHCCCCCEEHHHHHHHHHHHCCCCCCCCCEEHHHHHHHHHHHHHHHHHHCC
HRGRYIAVWAVIYPLIVWWLMYGGFLGLERVETRQWGGLTLTLIIASVGIAGALPWGILL
CCCCEEEHHHHHHHHHHHHHHHCCHHCHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHH
ALGRRSHMPIVRILSVIFIEFWRGVPLITVLFMSSVMLPLFMAEGTSIDKLIRALVGVIL
HHCCCCCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHH
FQSAYVAEVVRGGLQALPKGQYEAAESLALGYWKTQGLVILPQALKLVIPGLVNTIIALF
HHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHEEECCCEEEEHHHHHHHHHHHHHHHHHHH
KDTSLVIIIGLFDLFSSVQQATVDPAWLGMSTEGYVFAALIYWIFCFSMSRYSQHLEKRF
CCCCCEEHHHHHHHHHHHHHHCCCHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
NTGRTPH
CCCCCCC
>Mature Secondary Structure 
TKVLLSHPPRPASHNSSRAMVWVRKNLFSSWSNSLLTIGCIWLMWELIPPLLNWAFLQA
CCCCCCCCCCCCCCCCCCEEEHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHEE
NWVGSTRADCTKAGACWVFIHERFGQFMYGLYPHDQRWRINLALLIGLVSIAPMFWKILP
CCCCCCCCHHHCCCCCEEHHHHHHHHHHHCCCCCCCCCEEHHHHHHHHHHHHHHHHHHCC
HRGRYIAVWAVIYPLIVWWLMYGGFLGLERVETRQWGGLTLTLIIASVGIAGALPWGILL
CCCCEEEHHHHHHHHHHHHHHHCCHHCHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHH
ALGRRSHMPIVRILSVIFIEFWRGVPLITVLFMSSVMLPLFMAEGTSIDKLIRALVGVIL
HHCCCCCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHH
FQSAYVAEVVRGGLQALPKGQYEAAESLALGYWKTQGLVILPQALKLVIPGLVNTIIALF
HHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHEEECCCEEEEHHHHHHHHHHHHHHHHHHH
KDTSLVIIIGLFDLFSSVQQATVDPAWLGMSTEGYVFAALIYWIFCFSMSRYSQHLEKRF
CCCCCEEHHHHHHHHHHHHHHCCCHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
NTGRTPH
CCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9278503 [H]