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The map label for this gene is aapQ

Identifier: 218702041

GI number: 218702041

Start: 3934671

End: 3935852

Strand: Direct

Name: aapQ

Synonym: ECIAI39_3770

Alternate gene names: 218702041

Gene position: 3934671-3935852 (Clockwise)

Preceding gene: 218702040

Following gene: 218702042

Centisome position: 76.67

GC content: 50.34

Gene sequence:

>1182_bases
ATGTCTCATCGCCGCTCAACCGTTAAAGGCTCACTCTCCTTTGCCAACCCTACGGTTCGCGCCTGGTTATTCCAGATCCT
TGCCGTTGTTGCTGTTGTCGGCATTGTTGGTTGGCTATTTCACAACACTGTGACGAATCTCAGTAATCGTGGCATTACTT
CAGGTTTTGCCTTTCTGGATCGCGGCGCTGGCTTCGGTATTGTCCAGCATTTGATCGATTACCAGCAGGGTGATACCTAC
GGACGCGTTTTCATTGTTGGCTTACTCAATACGCTACTGGTTTCTGCATTGTGTATTGTATTCGCTTCTGTTCTGGGCTT
CTTTATCGGTCTGGCGCGACTTTCGGATAACTGGCTGCTACGAAAGCTTTCCACAATTTATATTGAGATCTTCCGTAATA
TTCCGCCGCTGCTGCAAATCTTCTTCTGGTACTTTGCCGTGTTGCGCAATTTGCCCGGACCACGCCAGGCAGTGAGTGCG
TTTGATCTGGCCTTTTTGAGCAATCGTGGGCTTTATATTCCGTCGCCGCAGCTGGGAGACGGATTTATTGCGTTTATCCT
GGCTGTTGTTATGGCTATAGTCCTTTCTGTTGGGCTATTCCTCTTTAATAAAACATACCAGATAAAAACCGGACAACTGC
GCCGCACCTGGCCGATCGCCGCAGTGTTGATCATAGGTTTGCCTTTACTGGCGCAATGGCTTTTTGGCGCAGCACTACAC
TGGGATGTCCCAGCCTTACGAGGCTTTAACTTCCGTGGCGGGATGGTTTTAATTCCTGAACTGGCAGCCTTAACGCTGGC
ACTTTCGGTTTATACCTCTGCATTTATCGCCGAGATTATCCGCGCTGGGATCCAGGCAGTGCCTTATGGTCAACATGAAG
CGGCTCGGTCACTGGGATTACCCAATCCGGTTACGCTACGCCAGGTCATTATTCCCCAGGCACTGCGAGTGATCATTCCG
CCGTTAACCAGCCAGTATCTCAACATCGTCAAAAACTCCTCTCTTGCCGCCGCTATTGGCTATCCGGATATGGTTTCGCT
GTTTGCTGGCACCGTGCTGAACCAGACGGGGCAAGCCATCGAGACGATAGCCATGACCATGTCGGTCTATCTGATTATCA
GCCTGACTATCTCGCTGCTGATGAATATCTATAACCGCCGCATCGCGATCGTTGAACGCTAA

Upstream 100 bases:

>100_bases
GGCGGTATTCAGTACGCACCGCCCGTGCGTTAAGTCGGTGTGAGGTAACGAGCGTCGCTACGGCGGCGCTCTCTTCAGCG
TTATGCTTTCCGAGGTTTCT

Downstream 100 bases:

>100_bases
GGAGTCATGATGACAAAAGTATTGCTGTCTCATCCCCCGCGCCCGGCGAGCCATAACTCAAGCCGCGCGATGGTGTGGGT
GCGAAAAAATCTGTTCTCCA

Product: amino-acid ABC transporter membrane protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 393; Mature: 392

Protein sequence:

>393_residues
MSHRRSTVKGSLSFANPTVRAWLFQILAVVAVVGIVGWLFHNTVTNLSNRGITSGFAFLDRGAGFGIVQHLIDYQQGDTY
GRVFIVGLLNTLLVSALCIVFASVLGFFIGLARLSDNWLLRKLSTIYIEIFRNIPPLLQIFFWYFAVLRNLPGPRQAVSA
FDLAFLSNRGLYIPSPQLGDGFIAFILAVVMAIVLSVGLFLFNKTYQIKTGQLRRTWPIAAVLIIGLPLLAQWLFGAALH
WDVPALRGFNFRGGMVLIPELAALTLALSVYTSAFIAEIIRAGIQAVPYGQHEAARSLGLPNPVTLRQVIIPQALRVIIP
PLTSQYLNIVKNSSLAAAIGYPDMVSLFAGTVLNQTGQAIETIAMTMSVYLIISLTISLLMNIYNRRIAIVER

Sequences:

>Translated_393_residues
MSHRRSTVKGSLSFANPTVRAWLFQILAVVAVVGIVGWLFHNTVTNLSNRGITSGFAFLDRGAGFGIVQHLIDYQQGDTY
GRVFIVGLLNTLLVSALCIVFASVLGFFIGLARLSDNWLLRKLSTIYIEIFRNIPPLLQIFFWYFAVLRNLPGPRQAVSA
FDLAFLSNRGLYIPSPQLGDGFIAFILAVVMAIVLSVGLFLFNKTYQIKTGQLRRTWPIAAVLIIGLPLLAQWLFGAALH
WDVPALRGFNFRGGMVLIPELAALTLALSVYTSAFIAEIIRAGIQAVPYGQHEAARSLGLPNPVTLRQVIIPQALRVIIP
PLTSQYLNIVKNSSLAAAIGYPDMVSLFAGTVLNQTGQAIETIAMTMSVYLIISLTISLLMNIYNRRIAIVER
>Mature_392_residues
SHRRSTVKGSLSFANPTVRAWLFQILAVVAVVGIVGWLFHNTVTNLSNRGITSGFAFLDRGAGFGIVQHLIDYQQGDTYG
RVFIVGLLNTLLVSALCIVFASVLGFFIGLARLSDNWLLRKLSTIYIEIFRNIPPLLQIFFWYFAVLRNLPGPRQAVSAF
DLAFLSNRGLYIPSPQLGDGFIAFILAVVMAIVLSVGLFLFNKTYQIKTGQLRRTWPIAAVLIIGLPLLAQWLFGAALHW
DVPALRGFNFRGGMVLIPELAALTLALSVYTSAFIAEIIRAGIQAVPYGQHEAARSLGLPNPVTLRQVIIPQALRVIIPP
LTSQYLNIVKNSSLAAAIGYPDMVSLFAGTVLNQTGQAIETIAMTMSVYLIISLTISLLMNIYNRRIAIVER

Specific function: Probably part of the binding-protein-dependent transport system ydhWXYZ for an amino acid; probably responsible for the translocation of the substrate across the membrane [H]

COG id: COG4597

COG function: function code E; ABC-type amino acid transport system, permease component

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transmembrane type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI48994930, Length=393, Percent_Identity=99.4910941475827, Blast_Score=773, Evalue=0.0,
Organism=Escherichia coli, GI1786874, Length=123, Percent_Identity=39.8373983739837, Blast_Score=97, Evalue=1e-21,
Organism=Escherichia coli, GI1788226, Length=171, Percent_Identity=35.0877192982456, Blast_Score=80, Evalue=2e-16,
Organism=Escherichia coli, GI1786873, Length=130, Percent_Identity=34.6153846153846, Blast_Score=80, Evalue=3e-16,
Organism=Escherichia coli, GI87082239, Length=120, Percent_Identity=33.3333333333333, Blast_Score=70, Evalue=2e-13,
Organism=Escherichia coli, GI1787030, Length=134, Percent_Identity=31.3432835820896, Blast_Score=69, Evalue=7e-13,
Organism=Escherichia coli, GI1788645, Length=162, Percent_Identity=27.7777777777778, Blast_Score=63, Evalue=3e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010065
- InterPro:   IPR000515 [H]

Pfam domain/function: PF00528 BPD_transp_1 [H]

EC number: NA

Molecular weight: Translated: 43192; Mature: 43061

Theoretical pI: Translated: 10.68; Mature: 10.68

Prosite motif: PS50928 ABC_TM1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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HHHHHHHHHHHHHHHHHHHHHHHHCCEEEEEEC
>Mature Secondary Structure 
SHRRSTVKGSLSFANPTVRAWLFQILAVVAVVGIVGWLFHNTVTNLSNRGITSGFAFLD
CCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHH
RGAGFGIVQHLIDYQQGDTYGRVFIVGLLNTLLVSALCIVFASVLGFFIGLARLSDNWLL
CCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHH
RKLSTIYIEIFRNIPPLLQIFFWYFAVLRNLPGPRQAVSAFDLAFLSNRGLYIPSPQLGD
HHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCEECCCCCCCC
GFIAFILAVVMAIVLSVGLFLFNKTYQIKTGQLRRTWPIAAVLIIGLPLLAQWLFGAALH
HHHHHHHHHHHHHHHHHHHHHHCCCEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
WDVPALRGFNFRGGMVLIPELAALTLALSVYTSAFIAEIIRAGIQAVPYGQHEAARSLGL
CCCHHHCCCCCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHCCC
PNPVTLRQVIIPQALRVIIPPLTSQYLNIVKNSSLAAAIGYPDMVSLFAGTVLNQTGQAI
CCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCEEECCCHHHHHHHHHHHHHHHHHHH
ETIAMTMSVYLIISLTISLLMNIYNRRIAIVER
HHHHHHHHHHHHHHHHHHHHHHHHCCEEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9278503 [H]