Click here to switch to the map view.

The map label for this gene is talA

Identifier: 218700920

GI number: 218700920

Start: 2695437

End: 2696387

Strand: Direct

Name: talA

Synonym: ECIAI39_2601

Alternate gene names: 218700920

Gene position: 2695437-2696387 (Clockwise)

Preceding gene: 218700902

Following gene: 218700921

Centisome position: 52.52

GC content: 49.63

Gene sequence:

>951_bases
ATGAACGAGTTAGACGGCATCAAACAGTTCACCACTGTCGTGGCAGACAGCGGCGATATTGAGTCCATTCGCCATTATCA
TCCCCAGGATGCCACCACCAATCCTTCGCTGTTACTCAAGGCTGCCGGATTATCACAATATGAGCATTTAATAGACGATG
CTATCGCCTGGGGTAGAAAAAATGGCAAAACCCAGGAACAACAGGTGGTCGCAGCGTGTGACAAACTGGCGGTCAATTTC
GGTGCTGAAATTCTCAAAATCGTACCCGGTCGCGTGTCAACAGAAGTTGATGCACGCCTCTCTTTTGATAAAGAAAAGAG
TATTGAAAAGGCCCGCCATCTGGTGGACTTGTATCAGCAACAAGGCGTTGAGAAATCACGCATTTTGATCAAGCTGGCTT
CAACCTGGGAAGGAATTCGCGCGGCAGAAGAACTGGAAAAAGAAGGTATTAACTGCAACCTGACGCTGCTGTTTTCTTTT
GCCCAGGCGCGGGCCTGTGCAGAAGCAGGCGTTTTTCTGATTTCGCCGTTTGTCGGGCGTATTTATGACTGGTATCAGGC
ACGCAAGCCGATGGACCCGTATGTGGTGGAAGAAGATCCAGGCGTTAAATCAGTACGCAATATCTACGACTACTATAAGC
AACACCACTATGAAACCATTGTGATGGGCGCGAGCTTCCGTCGCACCGAACAAATCCTCGCCTTAACCGGCTGCGATCGA
CTGACTATCGCACCGAATTTGCTGAAGGAGCTGCAGGAAAAAGTTTCGCCAGTGGTACGTAAATTAATCCCACCTTCTCA
GACGTTCCCACGCCCAGCTCCCATGAGCGAAGCGGAGTTCCGTTGGGAGCACAATCAGGATGCAATGGCGGTAGAAAAAC
TGTCTGAAGGCATTCGTCTGTTCGCCGTTGATCAACGCAAACTGGAAGATCTTCTTGCCGCCAAACTATAA

Upstream 100 bases:

>100_bases
ATGCCTGTCTGCTATGCTTTTTTGATGCGTTTAGCGAAATTTCTCAGAAGTGTGAATTAACGCACTCATCTAACACTTTA
CTTTTCAAGGAGTATTTCCT

Downstream 100 bases:

>100_bases
ACCAGCCACGGAGTGTTATATGTCCCGAAAAGACCTTGCCAATGCGATTCGCGCACTCAGTATGGATGCGGTACAAAAAG
CCAATTCTGGTCATCCCGGC

Product: transaldolase A

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 316; Mature: 316

Protein sequence:

>316_residues
MNELDGIKQFTTVVADSGDIESIRHYHPQDATTNPSLLLKAAGLSQYEHLIDDAIAWGRKNGKTQEQQVVAACDKLAVNF
GAEILKIVPGRVSTEVDARLSFDKEKSIEKARHLVDLYQQQGVEKSRILIKLASTWEGIRAAEELEKEGINCNLTLLFSF
AQARACAEAGVFLISPFVGRIYDWYQARKPMDPYVVEEDPGVKSVRNIYDYYKQHHYETIVMGASFRRTEQILALTGCDR
LTIAPNLLKELQEKVSPVVRKLIPPSQTFPRPAPMSEAEFRWEHNQDAMAVEKLSEGIRLFAVDQRKLEDLLAAKL

Sequences:

>Translated_316_residues
MNELDGIKQFTTVVADSGDIESIRHYHPQDATTNPSLLLKAAGLSQYEHLIDDAIAWGRKNGKTQEQQVVAACDKLAVNF
GAEILKIVPGRVSTEVDARLSFDKEKSIEKARHLVDLYQQQGVEKSRILIKLASTWEGIRAAEELEKEGINCNLTLLFSF
AQARACAEAGVFLISPFVGRIYDWYQARKPMDPYVVEEDPGVKSVRNIYDYYKQHHYETIVMGASFRRTEQILALTGCDR
LTIAPNLLKELQEKVSPVVRKLIPPSQTFPRPAPMSEAEFRWEHNQDAMAVEKLSEGIRLFAVDQRKLEDLLAAKL
>Mature_316_residues
MNELDGIKQFTTVVADSGDIESIRHYHPQDATTNPSLLLKAAGLSQYEHLIDDAIAWGRKNGKTQEQQVVAACDKLAVNF
GAEILKIVPGRVSTEVDARLSFDKEKSIEKARHLVDLYQQQGVEKSRILIKLASTWEGIRAAEELEKEGINCNLTLLFSF
AQARACAEAGVFLISPFVGRIYDWYQARKPMDPYVVEEDPGVKSVRNIYDYYKQHHYETIVMGASFRRTEQILALTGCDR
LTIAPNLLKELQEKVSPVVRKLIPPSQTFPRPAPMSEAEFRWEHNQDAMAVEKLSEGIRLFAVDQRKLEDLLAAKL

Specific function: Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway [H]

COG id: COG0176

COG function: function code G; Transaldolase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the transaldolase family. Type 1 subfamily [H]

Homologues:

Organism=Homo sapiens, GI5803187, Length=317, Percent_Identity=59.6214511041009, Blast_Score=371, Evalue=1e-103,
Organism=Escherichia coli, GI1788807, Length=316, Percent_Identity=99.6835443037975, Blast_Score=654, Evalue=0.0,
Organism=Escherichia coli, GI1786189, Length=312, Percent_Identity=64.1025641025641, Blast_Score=421, Evalue=1e-119,
Organism=Caenorhabditis elegans, GI25153750, Length=320, Percent_Identity=53.4375, Blast_Score=338, Evalue=3e-93,
Organism=Caenorhabditis elegans, GI25153752, Length=166, Percent_Identity=53.0120481927711, Blast_Score=170, Evalue=1e-42,
Organism=Caenorhabditis elegans, GI17570473, Length=98, Percent_Identity=51.0204081632653, Blast_Score=87, Evalue=1e-17,
Organism=Saccharomyces cerevisiae, GI6323386, Length=321, Percent_Identity=58.2554517133956, Blast_Score=333, Evalue=3e-92,
Organism=Saccharomyces cerevisiae, GI6321480, Length=314, Percent_Identity=54.7770700636943, Blast_Score=333, Evalue=3e-92,
Organism=Drosophila melanogaster, GI45549185, Length=319, Percent_Identity=56.7398119122257, Blast_Score=357, Evalue=7e-99,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013785
- InterPro:   IPR001585
- InterPro:   IPR004730
- InterPro:   IPR018225 [H]

Pfam domain/function: PF00923 Transaldolase [H]

EC number: =2.2.1.2 [H]

Molecular weight: Translated: 35687; Mature: 35687

Theoretical pI: Translated: 6.19; Mature: 6.19

Prosite motif: PS01054 TRANSALDOLASE_1 ; PS00958 TRANSALDOLASE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNELDGIKQFTTVVADSGDIESIRHYHPQDATTNPSLLLKAAGLSQYEHLIDDAIAWGRK
CCHHHHHHHHHHHHCCCCCHHHHHHCCCCCCCCCHHHEEECCCHHHHHHHHHHHHHHCCC
NGKTQEQQVVAACDKLAVNFGAEILKIVPGRVSTEVDARLSFDKEKSIEKARHLVDLYQQ
CCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHCCCHHHHHHHHHHHHHHHHH
QGVEKSRILIKLASTWEGIRAAEELEKEGINCNLTLLFSFAQARACAEAGVFLISPFVGR
CCCCHHHHHEEEHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHCCHHHHHHHHHH
IYDWYQARKPMDPYVVEEDPGVKSVRNIYDYYKQHHYETIVMGASFRRTEQILALTGCDR
HHHHHHHCCCCCCEEECCCCCHHHHHHHHHHHHHHCCCEEEECCCHHHHHHHHHHCCCCC
LTIAPNLLKELQEKVSPVVRKLIPPSQTFPRPAPMSEAEFRWEHNQDAMAVEKLSEGIRL
EEECHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHCCCCCCCHHHHHHHHCCCEE
FAVDQRKLEDLLAAKL
EEECHHHHHHHHHHCC
>Mature Secondary Structure
MNELDGIKQFTTVVADSGDIESIRHYHPQDATTNPSLLLKAAGLSQYEHLIDDAIAWGRK
CCHHHHHHHHHHHHCCCCCHHHHHHCCCCCCCCCHHHEEECCCHHHHHHHHHHHHHHCCC
NGKTQEQQVVAACDKLAVNFGAEILKIVPGRVSTEVDARLSFDKEKSIEKARHLVDLYQQ
CCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHCCCHHHHHHHHHHHHHHHHH
QGVEKSRILIKLASTWEGIRAAEELEKEGINCNLTLLFSFAQARACAEAGVFLISPFVGR
CCCCHHHHHEEEHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHCCHHHHHHHHHH
IYDWYQARKPMDPYVVEEDPGVKSVRNIYDYYKQHHYETIVMGASFRRTEQILALTGCDR
HHHHHHHCCCCCCEEECCCCCHHHHHHHHHHHHHHCCCEEEECCCHHHHHHHHHHCCCCC
LTIAPNLLKELQEKVSPVVRKLIPPSQTFPRPAPMSEAEFRWEHNQDAMAVEKLSEGIRL
EEECHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHCCCCCCCHHHHHHHHCCCEE
FAVDQRKLEDLLAAKL
EEECHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA