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The map label for this gene is dsdX

Identifier: 218700833

GI number: 218700833

Start: 2599649

End: 2600986

Strand: Direct

Name: dsdX

Synonym: ECIAI39_2508

Alternate gene names: 218700833

Gene position: 2599649-2600986 (Clockwise)

Preceding gene: 218700831

Following gene: 218700834

Centisome position: 50.65

GC content: 49.03

Gene sequence:

>1338_bases
ATGCACTCTCAAATCTGGGTTGTGAGCACGCTGCTTATCAGCATCGTGTTAATTGTACTGACCATCGTGAAGTTCAAATT
CCACCCGTTTCTGGCGCTGTTGCTGGCCAGCTTCTTCGTGGGAACGATGATGGGTATGGGACCACTGGATATGGTAAATG
CTATTGAAAGTGGAATTGGCGGAACGCTGGGGTTCCTTGCTGCGGTTATCGGCCTGGGCACGATACTGGGAAAAATGATG
GAAGTATCCGGGGCCGCAGAAAGAATTGGTCTGACACTTCAACGCTGTCGCTGGCTTTCAGCTGATGTCATTATGGTGCT
GGTTGGCCTGATTTGCGGCATCACGCTGTTTGTTGAAGTGGGCGTCGTGCTATTGATTCCTCTGGCTTTTTCAATTGCCA
AAAAAACCAATACCTCATTGTTAAAGCTGGCCATTCCGCTGTGTACCGCATTGATGGCAGTGCATTGCGTGGTTCCCCCA
CATCCGGCTGCTTTATATGTTGCCAATAAGCTGGGCGCAGATATCGGTTCGGTGATCGTCTACGGTTTGCTGGTTGGGCT
GATGGCATCACTGATCGGTGGCCCACTTTTCCTTAAATTTCTGGGTCAACGACTGCCCTTTAAACCTGTACCCACAGAGT
TTGCCGATCTCAAAGTTCGCGATGAAAAAACACTACCGTCATTAGGCGCAACGTTATTCACCATACTGCTACCCATTGCG
CTGATGTTGGTTAAAACGATTGCCGAATTGAATATGGCGCGTGAGAGTGGTTTGTATACCTTGCTTGAGTTTATTGGCAA
CCCTATTACTGCCATGTTTATCGCCGTGTTTGTCGCCTATTATGTGTTGGGTATACGCCAGCATATGAGCATGGGGACAA
TGCTCACACATACGGAAAATGGCTTCGGTTCTATTGCTAATATTTTGCTGATTATCGGGGCCGGAGGCGCATTCAACGCC
ATTTTAAAAAGCAGCAGTCTCGCTGATACGCTGGCAGTTATTCTCTCCAATATGCATATGCACCCGATTCTTCTGGCCTG
GTTGGTGGCACTTATTCTGCATGCTGCAGTGGGCTCCGCTACGGTGGCAATGATGGGGGCAACGGCAATTGTTGCACCCA
TGCTGCCGCTGTATCCCGACATCAGCCCGGAAATTATTGCGATTGCTATCGGTTCAGGTGCGATTGGCTGCACGATCGTT
ACGGACTCGCTTTTCTGGCTGGTGAAGCAATATTGCGGCGCTACGCTCAATGAAACATTTAAATACTATACGACAGCGAC
ATTTATCGCTTCAGTCATCGCTCTGGCGGGCACATTCCTGCTGTCATTTATCATCTAA

Upstream 100 bases:

>100_bases
GATGCAATTTAGCTCATGTGAAAGGCAAATTTTATCGTTTGTCAGCCTGCGTTGTTTTTTTGTCCAATATCATCAGGTTA
ATCACAGGGGAAGGTGAGAT

Downstream 100 bases:

>100_bases
GCGCAAAGAGACGTACTATGGAAAACGCTAAAATGAACTCGCTCATCGCCCAGTATCCGTTGGTAAAGGATCTGGTTGCT
CTTAAAGAAACCACCTGGTT

Product: permease DsdX

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 445; Mature: 445

Protein sequence:

>445_residues
MHSQIWVVSTLLISIVLIVLTIVKFKFHPFLALLLASFFVGTMMGMGPLDMVNAIESGIGGTLGFLAAVIGLGTILGKMM
EVSGAAERIGLTLQRCRWLSADVIMVLVGLICGITLFVEVGVVLLIPLAFSIAKKTNTSLLKLAIPLCTALMAVHCVVPP
HPAALYVANKLGADIGSVIVYGLLVGLMASLIGGPLFLKFLGQRLPFKPVPTEFADLKVRDEKTLPSLGATLFTILLPIA
LMLVKTIAELNMARESGLYTLLEFIGNPITAMFIAVFVAYYVLGIRQHMSMGTMLTHTENGFGSIANILLIIGAGGAFNA
ILKSSSLADTLAVILSNMHMHPILLAWLVALILHAAVGSATVAMMGATAIVAPMLPLYPDISPEIIAIAIGSGAIGCTIV
TDSLFWLVKQYCGATLNETFKYYTTATFIASVIALAGTFLLSFII

Sequences:

>Translated_445_residues
MHSQIWVVSTLLISIVLIVLTIVKFKFHPFLALLLASFFVGTMMGMGPLDMVNAIESGIGGTLGFLAAVIGLGTILGKMM
EVSGAAERIGLTLQRCRWLSADVIMVLVGLICGITLFVEVGVVLLIPLAFSIAKKTNTSLLKLAIPLCTALMAVHCVVPP
HPAALYVANKLGADIGSVIVYGLLVGLMASLIGGPLFLKFLGQRLPFKPVPTEFADLKVRDEKTLPSLGATLFTILLPIA
LMLVKTIAELNMARESGLYTLLEFIGNPITAMFIAVFVAYYVLGIRQHMSMGTMLTHTENGFGSIANILLIIGAGGAFNA
ILKSSSLADTLAVILSNMHMHPILLAWLVALILHAAVGSATVAMMGATAIVAPMLPLYPDISPEIIAIAIGSGAIGCTIV
TDSLFWLVKQYCGATLNETFKYYTTATFIASVIALAGTFLLSFII
>Mature_445_residues
MHSQIWVVSTLLISIVLIVLTIVKFKFHPFLALLLASFFVGTMMGMGPLDMVNAIESGIGGTLGFLAAVIGLGTILGKMM
EVSGAAERIGLTLQRCRWLSADVIMVLVGLICGITLFVEVGVVLLIPLAFSIAKKTNTSLLKLAIPLCTALMAVHCVVPP
HPAALYVANKLGADIGSVIVYGLLVGLMASLIGGPLFLKFLGQRLPFKPVPTEFADLKVRDEKTLPSLGATLFTILLPIA
LMLVKTIAELNMARESGLYTLLEFIGNPITAMFIAVFVAYYVLGIRQHMSMGTMLTHTENGFGSIANILLIIGAGGAFNA
ILKSSSLADTLAVILSNMHMHPILLAWLVALILHAAVGSATVAMMGATAIVAPMLPLYPDISPEIIAIAIGSGAIGCTIV
TDSLFWLVKQYCGATLNETFKYYTTATFIASVIALAGTFLLSFII

Specific function: Probable permease for an unknown substrate [H]

COG id: COG2610

COG function: function code GE; H+/gluconate symporter and related permeases

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the gntP permease family [H]

Homologues:

Organism=Escherichia coli, GI1788707, Length=445, Percent_Identity=99.1011235955056, Blast_Score=870, Evalue=0.0,
Organism=Escherichia coli, GI48994935, Length=440, Percent_Identity=36.8181818181818, Blast_Score=267, Evalue=1e-72,
Organism=Escherichia coli, GI1790716, Length=430, Percent_Identity=32.5581395348837, Blast_Score=246, Evalue=2e-66,
Organism=Escherichia coli, GI1790776, Length=446, Percent_Identity=31.1659192825112, Blast_Score=222, Evalue=3e-59,
Organism=Escherichia coli, GI2367370, Length=427, Percent_Identity=33.7236533957845, Blast_Score=219, Evalue=3e-58,
Organism=Escherichia coli, GI48994939, Length=429, Percent_Identity=35.6643356643357, Blast_Score=207, Evalue=1e-54,
Organism=Escherichia coli, GI1789097, Length=437, Percent_Identity=29.7482837528604, Blast_Score=166, Evalue=3e-42,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003474 [H]

Pfam domain/function: PF02447 GntP_permease [H]

EC number: NA

Molecular weight: Translated: 47152; Mature: 47152

Theoretical pI: Translated: 8.14; Mature: 8.14

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
4.7 %Met     (Translated Protein)
6.1 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
4.7 %Met     (Mature Protein)
6.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MHSQIWVVSTLLISIVLIVLTIVKFKFHPFLALLLASFFVGTMMGMGPLDMVNAIESGIG
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCC
GTLGFLAAVIGLGTILGKMMEVSGAAERIGLTLQRCRWLSADVIMVLVGLICGITLFVEV
HHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHH
GVVLLIPLAFSIAKKTNTSLLKLAIPLCTALMAVHCVVPPHPAALYVANKLGADIGSVIV
HHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHCCHHHHHHH
YGLLVGLMASLIGGPLFLKFLGQRLPFKPVPTEFADLKVRDEKTLPSLGATLFTILLPIA
HHHHHHHHHHHHCHHHHHHHHHCCCCCCCCCCCHHCCEECCCCCCHHHHHHHHHHHHHHH
LMLVKTIAELNMARESGLYTLLEFIGNPITAMFIAVFVAYYVLGIRQHMSMGTMLTHTEN
HHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHCHHHEECCC
GFGSIANILLIIGAGGAFNAILKSSSLADTLAVILSNMHMHPILLAWLVALILHAAVGSA
CHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHH
TVAMMGATAIVAPMLPLYPDISPEIIAIAIGSGAIGCTIVTDSLFWLVKQYCGATLNETF
HHHHHHHHHHHHHHHHCCCCCCCCEEEEEECCCCCCHHHHHHHHHHHHHHHHCCCHHHHH
KYYTTATFIASVIALAGTFLLSFII
HHHHHHHHHHHHHHHHHHHHHHHHC
>Mature Secondary Structure
MHSQIWVVSTLLISIVLIVLTIVKFKFHPFLALLLASFFVGTMMGMGPLDMVNAIESGIG
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCC
GTLGFLAAVIGLGTILGKMMEVSGAAERIGLTLQRCRWLSADVIMVLVGLICGITLFVEV
HHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHH
GVVLLIPLAFSIAKKTNTSLLKLAIPLCTALMAVHCVVPPHPAALYVANKLGADIGSVIV
HHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHCCHHHHHHH
YGLLVGLMASLIGGPLFLKFLGQRLPFKPVPTEFADLKVRDEKTLPSLGATLFTILLPIA
HHHHHHHHHHHHCHHHHHHHHHCCCCCCCCCCCHHCCEECCCCCCHHHHHHHHHHHHHHH
LMLVKTIAELNMARESGLYTLLEFIGNPITAMFIAVFVAYYVLGIRQHMSMGTMLTHTEN
HHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHCHHHEECCC
GFGSIANILLIIGAGGAFNAILKSSSLADTLAVILSNMHMHPILLAWLVALILHAAVGSA
CHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHH
TVAMMGATAIVAPMLPLYPDISPEIIAIAIGSGAIGCTIVTDSLFWLVKQYCGATLNETF
HHHHHHHHHHHHHHHHCCCCCCCCEEEEEECCCCCCHHHHHHHHHHHHHHHHCCCHHHHH
KYYTTATFIASVIALAGTFLLSFII
HHHHHHHHHHHHHHHHHHHHHHHHC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7592420; 3275618; 9205837; 9278503; 3029015; 1659648; 12218016 [H]