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The map label for this gene is ydhM

Identifier: 218699783

GI number: 218699783

Start: 1480623

End: 1481138

Strand: Reverse

Name: ydhM

Synonym: ECIAI39_1407

Alternate gene names: 218699783

Gene position: 1481138-1480623 (Counterclockwise)

Preceding gene: 218699786

Following gene: 218699782

Centisome position: 28.86

GC content: 52.33

Gene sequence:

>516_bases
ATGGGGCTAAGCGAACTCCTAAAAACTGCTGAAGTGCCGAAAGGGTCCTTCTATCACTACTTTCGCTCTAAAGAAGCGTT
TGGCGTTGCCATGCTTGAGCGCCATTACGCCGCATATCACCAGCGACTGACTGAGTTGCTGCAATCCGGCGAAGGTAACT
ACCGCGACCGCATACTGGCTTATTACCAGCAAACACTGAACCAGTTTTGCCAACATGGAACCATCAGTGGTTGCCTGACA
GTAAAACTCTCTGCCGAAGTGTGCGATCTGTCAGAAGATATGCGTAGCGCGATGGATAAAGGCGCTCGCGGCGTGATCGC
CCTGCTCTCGCAGGCGCTGGAAAATGGCCGTGATAGCCATTGTTTAACCTTTTGTGGCGAACCGCTGCAACAGGCACAAG
TGCTTTACGCTCTATGGCTGGGTGCGAATCTGCAGGCCAAAATTTCGCGCAATTCCGAGCCACTGGAAAACGCGCTGGCA
CATGTAAAAACCATTATTGCGACGCCTGCCGTTTAG

Upstream 100 bases:

>100_bases
TACTACACTCCAACGCATGAACAAACACACCGAACATGATACTCGCGAACATCTCCTGGCGACGGGCGAGCAACTTTGCC
TGCAACGTGGATTCACCGGG

Downstream 100 bases:

>100_bases
CAGGCATTTTTTATCACCAGACGACCGGGAGCCTTTATGTCATCTGAAAAACTGTATTCCCCACTGAAAGTGGGCGCGAT
CACGGCGGCAAACCGTATTT

Product: putative DNA-binding transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 171; Mature: 170

Protein sequence:

>171_residues
MGLSELLKTAEVPKGSFYHYFRSKEAFGVAMLERHYAAYHQRLTELLQSGEGNYRDRILAYYQQTLNQFCQHGTISGCLT
VKLSAEVCDLSEDMRSAMDKGARGVIALLSQALENGRDSHCLTFCGEPLQQAQVLYALWLGANLQAKISRNSEPLENALA
HVKTIIATPAV

Sequences:

>Translated_171_residues
MGLSELLKTAEVPKGSFYHYFRSKEAFGVAMLERHYAAYHQRLTELLQSGEGNYRDRILAYYQQTLNQFCQHGTISGCLT
VKLSAEVCDLSEDMRSAMDKGARGVIALLSQALENGRDSHCLTFCGEPLQQAQVLYALWLGANLQAKISRNSEPLENALA
HVKTIIATPAV
>Mature_170_residues
GLSELLKTAEVPKGSFYHYFRSKEAFGVAMLERHYAAYHQRLTELLQSGEGNYRDRILAYYQQTLNQFCQHGTISGCLTV
KLSAEVCDLSEDMRSAMDKGARGVIALLSQALENGRDSHCLTFCGEPLQQAQVLYALWLGANLQAKISRNSEPLENALAH
VKTIIATPAV

Specific function: Represses the transcription of the nemRA operon by binding to the nemR box [H]

COG id: COG1309

COG function: function code K; Transcriptional regulator

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH tetR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI145693141, Length=171, Percent_Identity=97.0760233918129, Blast_Score=345, Evalue=7e-97,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR009057
- InterPro:   IPR015893
- InterPro:   IPR011075
- InterPro:   IPR001647 [H]

Pfam domain/function: PF00440 TetR_N [H]

EC number: NA

Molecular weight: Translated: 18983; Mature: 18852

Theoretical pI: Translated: 7.10; Mature: 7.10

Prosite motif: PS50977 HTH_TETR_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.9 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
5.3 %Cys+Met (Translated Protein)
2.9 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGLSELLKTAEVPKGSFYHYFRSKEAFGVAMLERHYAAYHQRLTELLQSGEGNYRDRILA
CCHHHHHHHHCCCCCHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHH
YYQQTLNQFCQHGTISGCLTVKLSAEVCDLSEDMRSAMDKGARGVIALLSQALENGRDSH
HHHHHHHHHHHCCCCCCEEEEEECHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCC
CLTFCGEPLQQAQVLYALWLGANLQAKISRNSEPLENALAHVKTIIATPAV
HHHHCCCHHHHHHHHHHHHHCCCCEEECCCCCCHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure 
GLSELLKTAEVPKGSFYHYFRSKEAFGVAMLERHYAAYHQRLTELLQSGEGNYRDRILA
CHHHHHHHHCCCCCHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHH
YYQQTLNQFCQHGTISGCLTVKLSAEVCDLSEDMRSAMDKGARGVIALLSQALENGRDSH
HHHHHHHHHHHCCCCCCEEEEEECHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCC
CLTFCGEPLQQAQVLYALWLGANLQAKISRNSEPLENALAHVKTIIATPAV
HHHHCCCHHHHHHHHHHHHHCCCCEEECCCCCCHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12471157 [H]