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The map label for this gene is nanE

Identifier: 218698108

GI number: 218698108

Start: 5018143

End: 5018832

Strand: Direct

Name: nanE

Synonym: EC55989_4918

Alternate gene names: 218698108

Gene position: 5018143-5018832 (Clockwise)

Preceding gene: 218698107

Following gene: 218698109

Centisome position: 97.35

GC content: 54.78

Gene sequence:

>690_bases
ATGAAAACTGTACTGGATTCCCTGAAAGGTAAATTAATCGTCTCCTGTCAGGCTCTGGAAAATGAGCCTCTACATAGTCC
GTTTATTATGTCACGTATGGCGCTGGCGGCAGCACAAGGTGGTGCTGCAGGTATCCGTGCCAACAGCGTGGCGGATATTA
GTGCTATCAAAGAGATTGTCTCCCTTCCGATGATAGGGATTATCAAACGCGATTACCCTGGCAGTGAGGTGTTTATCACG
GCCACTCTCCGGGAAGTGGATGAGTTGATGACCGTTGAGCCGGAAATTATTGCCCTGGATGCTACTGCGCGCCCGCGCCC
TGGTGGTCAGACGCTGGAAGAACTGGTCACGCAGATCCGCGCTCGCTACCCGTCCGTACTTCTGATGGCAGATATAGCAA
CAGTAGAAGAGGCGGTGACAGCTGAACGTCTGGGTTTTGACTGTGTGGGCACTACGCTCTACGGCTATACCGCAGAAACT
GCCAGGCATGTGCTGGCGGAAAATGACTGTGGATTCTTACGTGAGGTCCTGGCAGCGGTCAGCGTTCCGGTTGTGGCGGA
AGGGAACGTCGATACCCCGGAACGTGCCGCACGTTGCCTGACATTAGGCGCTCATACCGTGGTGGTTGGGGGGGCAATCA
CTCGTCCGCAGCAGATAACGACACGCTTTATCGCGGCGATCGCCTCGTAA

Upstream 100 bases:

>100_bases
CCGGAGCGCGTGGCGTGATTATTCGCGGCAACGGCGTTCAGGTGATTTATGGCCCTCATGTCACCATCATTAAAAACGAA
GTCGAAGAGATTTTATCGTA

Downstream 100 bases:

>100_bases
AGCACCGATGGGGTATGATACTTTGGTGGGGATAAGCGATAATTATCGCTTATCCCCATATTGAGAGTGTTATGCAGTAC
CCGATTAGCTAGATTTTCCA

Product: N-acetylmannosamine-6-phosphate 2-epimerase

Products: NA

Alternate protein names: ManNAc-6-P epimerase [H]

Number of amino acids: Translated: 229; Mature: 229

Protein sequence:

>229_residues
MKTVLDSLKGKLIVSCQALENEPLHSPFIMSRMALAAAQGGAAGIRANSVADISAIKEIVSLPMIGIIKRDYPGSEVFIT
ATLREVDELMTVEPEIIALDATARPRPGGQTLEELVTQIRARYPSVLLMADIATVEEAVTAERLGFDCVGTTLYGYTAET
ARHVLAENDCGFLREVLAAVSVPVVAEGNVDTPERAARCLTLGAHTVVVGGAITRPQQITTRFIAAIAS

Sequences:

>Translated_229_residues
MKTVLDSLKGKLIVSCQALENEPLHSPFIMSRMALAAAQGGAAGIRANSVADISAIKEIVSLPMIGIIKRDYPGSEVFIT
ATLREVDELMTVEPEIIALDATARPRPGGQTLEELVTQIRARYPSVLLMADIATVEEAVTAERLGFDCVGTTLYGYTAET
ARHVLAENDCGFLREVLAAVSVPVVAEGNVDTPERAARCLTLGAHTVVVGGAITRPQQITTRFIAAIAS
>Mature_229_residues
MKTVLDSLKGKLIVSCQALENEPLHSPFIMSRMALAAAQGGAAGIRANSVADISAIKEIVSLPMIGIIKRDYPGSEVFIT
ATLREVDELMTVEPEIIALDATARPRPGGQTLEELVTQIRARYPSVLLMADIATVEEAVTAERLGFDCVGTTLYGYTAET
ARHVLAENDCGFLREVLAAVSVPVVAEGNVDTPERAARCLTLGAHTVVVGGAITRPQQITTRFIAAIAS

Specific function: Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P) (Potential) [H]

COG id: COG3010

COG function: function code G; Putative N-acetylmannosamine-6-phosphate epimerase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the nanE family [H]

Homologues:

Organism=Escherichia coli, GI1789617, Length=220, Percent_Identity=41.3636363636364, Blast_Score=131, Evalue=5e-32,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013785
- InterPro:   IPR007260
- InterPro:   IPR011060 [H]

Pfam domain/function: PF04131 NanE [H]

EC number: =5.1.3.9 [H]

Molecular weight: Translated: 24315; Mature: 24315

Theoretical pI: Translated: 4.80; Mature: 4.80

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKTVLDSLKGKLIVSCQALENEPLHSPFIMSRMALAAAQGGAAGIRANSVADISAIKEIV
CCCHHHHCCCEEEEEEEHHCCCCCCCHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHH
SLPMIGIIKRDYPGSEVFITATLREVDELMTVEPEIIALDATARPRPGGQTLEELVTQIR
HCCHHHEEECCCCCCEEEEEHHHHHHHHHHCCCCCEEEEECCCCCCCCHHHHHHHHHHHH
ARYPSVLLMADIATVEEAVTAERLGFDCVGTTLYGYTAETARHVLAENDCGFLREVLAAV
HHCCCEEEHHHHHHHHHHHHHHHHCCHHHHHHHHCCHHHHHHHHHHCCCHHHHHHHHHHH
SVPVVAEGNVDTPERAARCLTLGAHTVVVGGAITRPQQITTRFIAAIAS
CCCEEECCCCCCHHHHHHHHHCCCCEEEECCCCCCCHHHHHHHHHHHCC
>Mature Secondary Structure
MKTVLDSLKGKLIVSCQALENEPLHSPFIMSRMALAAAQGGAAGIRANSVADISAIKEIV
CCCHHHHCCCEEEEEEEHHCCCCCCCHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHH
SLPMIGIIKRDYPGSEVFITATLREVDELMTVEPEIIALDATARPRPGGQTLEELVTQIR
HCCHHHEEECCCCCCEEEEEHHHHHHHHHHCCCCCEEEEECCCCCCCCHHHHHHHHHHHH
ARYPSVLLMADIATVEEAVTAERLGFDCVGTTLYGYTAETARHVLAENDCGFLREVLAAV
HHCCCEEEHHHHHHHHHHHHHHHHCCHHHHHHHHCCHHHHHHHHHHCCCHHHHHHHHHHH
SVPVVAEGNVDTPERAARCLTLGAHTVVVGGAITRPQQITTRFIAAIAS
CCCEEECCCCCCHHHHHHHHHCCCCEEEECCCCCCCHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA