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The map label for this gene is ptsG

Identifier: 218698107

GI number: 218698107

Start: 5016548

End: 5018143

Strand: Direct

Name: ptsG

Synonym: EC55989_4917

Alternate gene names: 218698107

Gene position: 5016548-5018143 (Clockwise)

Preceding gene: 218698105

Following gene: 218698108

Centisome position: 97.32

GC content: 51.94

Gene sequence:

>1596_bases
ATGGTAAAAATTTTTATCAATGATCAGGGAGATGAAAAAATGATGCAAATATTTAGCGGCGCTTCGTCAGGCGCATGGTT
TGAAAAAGCGCAGCGGTTCGGCAAATCGTTCATGCTGCCGATTGCGGTATTGCCCGCAGCGGGGTTGTTGTTGGGGATTG
GTGGGGCTCTGTCGAATCCCAATACGTTGACGGCCTACCCATTCTTGAATGTCGACTGGCTGCAGGCAATCTTCACAATC
ATGACCAGCGCAGGTTCTATTGTGTTTGCCAACCTGTCGGTACTCTTTGCGGTCGGCGTCGCCGTGGGGCTGGCGAAATC
GGATAAAGGCACTGCCGGGCTTGCGGCATTGCTAGCGTTTCTGGTGATGAATGCTACCATCAACGCCTTATTAACGCTAA
ATGGAACGTTGGCGCACAAGAACCCCGGTTCAGTTGGCCAGGGGATGACGCTTGGTATTCAGACACTGGAAACTGGTGTG
TTTGGTGGGGTGGTGATTGGTCTCGTCACCTGCACGTTACATAGCCGTTTCAATAAAGTCTCACTACCTCAGTTTCTCGG
TTTTTTTAGTGGTTCTCGTTTTGTACCCATTATCAGCTCCCTTGCCGCGATAGTAGTGGGTGCGGTTATGACGGTGGTGT
GGCCGCATTTCCAGAAACTCATTTTTGGACTGGGCGGCCTGGTGGATGCGACGGGCTATCTGGGGACGCTGTTGTACGGC
TTCATCCTGCGTATGCTTGGTCCACTGGGTTTACACCATATCTTTTATTTGCCGTTCTGGACGACGGCGCTGGGCGGCAG
TGAAATCGTCAACGGCCAGTTGGTTGAAGGTACGCAGCGGATTTTCTTTGCCCAACTTGCCGATCCGAATACGCAGCAGT
TCTACGCGGGTACCGCTCGCTTTATGTCCGGGCGCTTTATCACCATGATGTTTGGCCTGCTTGGCGCATGTCTGGCAATG
TACCATACGGCAAAGCCGGAGAATAGAAAGGTTGTCGCCGGACTACTTTTGTCGGCAGCCTTGACCTCTTTCCTGACGGG
AATCACTGAGCCTGTTGAGTTCTCCTTCCTGTTTGTCGCGCCCGTATTATACGTAATTCACGCCTTCTTCGATGGTCTGG
CGTTTATGGTCGCCCATATTTTACATATCACTATTGGGCAAACCTTTTCGGGCGGGCTTATCGATTTCCTTCTCTTCGGC
GTGTTGCAGGGGGAATCTAAAACAAACTGGATGTATGTCCCCATAGTGGGAATACCGTGGTTCTTCCTTTACTACTTCAC
TTTCCGCTATTTGATTAACCGCTTTGGCTGGCTGACGCCGGGTCGTGAGAACGTAACCCTGGTTGAATCCGGCCAGCCTC
AGAGTGAACGCGCAGCGGCAGTCATTGCCGGGCTGGGAGGCAAAGAGAATCTGGAAGAGGTGGACTGTTGCGCCACGCGC
CTGCGCGTGACGGTTAAAGAGAGCAGTAAGGTAGATGAAGCTGCGCTGAAAGTGACCGGAGCGCGTGGCGTGATTATTCG
CGGCAACGGCGTTCAGGTGATTTATGGCCCTCATGTCACCATCATTAAAAACGAAGTCGAAGAGATTTTATCGTAA

Upstream 100 bases:

>100_bases
CGATAGTGTGGCGGAAAGTAGGGGAGAGATGCCAGTCATTTTAAAAAAGTATGATCGGTGTCTTGGTTTTTGATGGTAAT
TTTCATTTTTAAAATTAGTT

Downstream 100 bases:

>100_bases
TGAAAACTGTACTGGATTCCCTGAAAGGTAAATTAATCGTCTCCTGTCAGGCTCTGGAAAATGAGCCTCTACATAGTCCG
TTTATTATGTCACGTATGGC

Product: PTS system, glucose-specific enzyme II, ABC component

Products: NA

Alternate protein names: EII-Glc/EIII-Glc; EIICBA-Glc; Glucose permease IIC component; PTS system glucose-specific EIIC component; Glucose-specific phosphotransferase enzyme IIB component; PTS system glucose-specific EIIB component; Glucose-specific phosphotransferase enzyme IIA component; PTS system glucose-specific EIIA component [H]

Number of amino acids: Translated: 531; Mature: 531

Protein sequence:

>531_residues
MVKIFINDQGDEKMMQIFSGASSGAWFEKAQRFGKSFMLPIAVLPAAGLLLGIGGALSNPNTLTAYPFLNVDWLQAIFTI
MTSAGSIVFANLSVLFAVGVAVGLAKSDKGTAGLAALLAFLVMNATINALLTLNGTLAHKNPGSVGQGMTLGIQTLETGV
FGGVVIGLVTCTLHSRFNKVSLPQFLGFFSGSRFVPIISSLAAIVVGAVMTVVWPHFQKLIFGLGGLVDATGYLGTLLYG
FILRMLGPLGLHHIFYLPFWTTALGGSEIVNGQLVEGTQRIFFAQLADPNTQQFYAGTARFMSGRFITMMFGLLGACLAM
YHTAKPENRKVVAGLLLSAALTSFLTGITEPVEFSFLFVAPVLYVIHAFFDGLAFMVAHILHITIGQTFSGGLIDFLLFG
VLQGESKTNWMYVPIVGIPWFFLYYFTFRYLINRFGWLTPGRENVTLVESGQPQSERAAAVIAGLGGKENLEEVDCCATR
LRVTVKESSKVDEAALKVTGARGVIIRGNGVQVIYGPHVTIIKNEVEEILS

Sequences:

>Translated_531_residues
MVKIFINDQGDEKMMQIFSGASSGAWFEKAQRFGKSFMLPIAVLPAAGLLLGIGGALSNPNTLTAYPFLNVDWLQAIFTI
MTSAGSIVFANLSVLFAVGVAVGLAKSDKGTAGLAALLAFLVMNATINALLTLNGTLAHKNPGSVGQGMTLGIQTLETGV
FGGVVIGLVTCTLHSRFNKVSLPQFLGFFSGSRFVPIISSLAAIVVGAVMTVVWPHFQKLIFGLGGLVDATGYLGTLLYG
FILRMLGPLGLHHIFYLPFWTTALGGSEIVNGQLVEGTQRIFFAQLADPNTQQFYAGTARFMSGRFITMMFGLLGACLAM
YHTAKPENRKVVAGLLLSAALTSFLTGITEPVEFSFLFVAPVLYVIHAFFDGLAFMVAHILHITIGQTFSGGLIDFLLFG
VLQGESKTNWMYVPIVGIPWFFLYYFTFRYLINRFGWLTPGRENVTLVESGQPQSERAAAVIAGLGGKENLEEVDCCATR
LRVTVKESSKVDEAALKVTGARGVIIRGNGVQVIYGPHVTIIKNEVEEILS
>Mature_531_residues
MVKIFINDQGDEKMMQIFSGASSGAWFEKAQRFGKSFMLPIAVLPAAGLLLGIGGALSNPNTLTAYPFLNVDWLQAIFTI
MTSAGSIVFANLSVLFAVGVAVGLAKSDKGTAGLAALLAFLVMNATINALLTLNGTLAHKNPGSVGQGMTLGIQTLETGV
FGGVVIGLVTCTLHSRFNKVSLPQFLGFFSGSRFVPIISSLAAIVVGAVMTVVWPHFQKLIFGLGGLVDATGYLGTLLYG
FILRMLGPLGLHHIFYLPFWTTALGGSEIVNGQLVEGTQRIFFAQLADPNTQQFYAGTARFMSGRFITMMFGLLGACLAM
YHTAKPENRKVVAGLLLSAALTSFLTGITEPVEFSFLFVAPVLYVIHAFFDGLAFMVAHILHITIGQTFSGGLIDFLLFG
VLQGESKTNWMYVPIVGIPWFFLYYFTFRYLINRFGWLTPGRENVTLVESGQPQSERAAAVIAGLGGKENLEEVDCCATR
LRVTVKESSKVDEAALKVTGARGVIIRGNGVQVIYGPHVTIIKNEVEEILS

Specific function: The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS), a major carbohydrate active -transport system, catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. This

COG id: COG1263

COG function: function code G; Phosphotransferase system IIC components, glucose/maltose/N-acetylglucosamine-specific

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PTS EIIC type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI1787908, Length=516, Percent_Identity=43.0232558139535, Blast_Score=389, Evalue=1e-109,
Organism=Escherichia coli, GI1787343, Length=504, Percent_Identity=43.0555555555556, Blast_Score=365, Evalue=1e-102,
Organism=Escherichia coli, GI1786894, Length=513, Percent_Identity=35.672514619883, Blast_Score=258, Evalue=7e-70,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011055
- InterPro:   IPR018113
- InterPro:   IPR004719
- InterPro:   IPR001127
- InterPro:   IPR001996
- InterPro:   IPR003352
- InterPro:   IPR013013
- InterPro:   IPR011535
- InterPro:   IPR011299 [H]

Pfam domain/function: PF00358 PTS_EIIA_1; PF00367 PTS_EIIB; PF02378 PTS_EIIC [H]

EC number: =2.7.1.69 [H]

Molecular weight: Translated: 57116; Mature: 57116

Theoretical pI: Translated: 8.57; Mature: 8.57

Prosite motif: PS01035 PTS_EIIB_TYPE_1_CYS ; PS51098 PTS_EIIB_TYPE_1 ; PS51103 PTS_EIIC_TYPE_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVKIFINDQGDEKMMQIFSGASSGAWFEKAQRFGKSFMLPIAVLPAAGLLLGIGGALSNP
CEEEEECCCCHHHHHHHHCCCCCCHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCCCCCC
NTLTAYPFLNVDWLQAIFTIMTSAGSIVFANLSVLFAVGVAVGLAKSDKGTAGLAALLAF
CCEEEECCCCHHHHHHHHHHHHCCCCEEEHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHH
LVMNATINALLTLNGTLAHKNPGSVGQGMTLGIQTLETGVFGGVVIGLVTCTLHSRFNKV
HHHHHHHHEEEEECCEEECCCCCCCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
SLPQFLGFFSGSRFVPIISSLAAIVVGAVMTVVWPHFQKLIFGLGGLVDATGYLGTLLYG
CHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHH
FILRMLGPLGLHHIFYLPFWTTALGGSEIVNGQLVEGTQRIFFAQLADPNTQQFYAGTAR
HHHHHHHHHHHHHHHHHHHHHHHCCCCHHCCCEEECCHHHEEEEECCCCCCHHHHHHHHH
FMSGRFITMMFGLLGACLAMYHTAKPENRKVVAGLLLSAALTSFLTGITEPVEFSFLFVA
HHCCHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHH
PVLYVIHAFFDGLAFMVAHILHITIGQTFSGGLIDFLLFGVLQGESKTNWMYVPIVGIPW
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHCCCCCCCEEEEEEHHHHH
FFLYYFTFRYLINRFGWLTPGRENVTLVESGQPQSERAAAVIAGLGGKENLEEVDCCATR
HHHHHHHHHHHHHHHCCCCCCCCCEEEEECCCCCHHHHHHHEECCCCCCCHHHHHHHHHH
LRVTVKESSKVDEAALKVTGARGVIIRGNGVQVIYGPHVTIIKNEVEEILS
HEEEECCCCCHHHHHHEEECCCEEEEECCCEEEEECCEEEEEHHHHHHHCC
>Mature Secondary Structure
MVKIFINDQGDEKMMQIFSGASSGAWFEKAQRFGKSFMLPIAVLPAAGLLLGIGGALSNP
CEEEEECCCCHHHHHHHHCCCCCCHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCCCCCC
NTLTAYPFLNVDWLQAIFTIMTSAGSIVFANLSVLFAVGVAVGLAKSDKGTAGLAALLAF
CCEEEECCCCHHHHHHHHHHHHCCCCEEEHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHH
LVMNATINALLTLNGTLAHKNPGSVGQGMTLGIQTLETGVFGGVVIGLVTCTLHSRFNKV
HHHHHHHHEEEEECCEEECCCCCCCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
SLPQFLGFFSGSRFVPIISSLAAIVVGAVMTVVWPHFQKLIFGLGGLVDATGYLGTLLYG
CHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHH
FILRMLGPLGLHHIFYLPFWTTALGGSEIVNGQLVEGTQRIFFAQLADPNTQQFYAGTAR
HHHHHHHHHHHHHHHHHHHHHHHCCCCHHCCCEEECCHHHEEEEECCCCCCHHHHHHHHH
FMSGRFITMMFGLLGACLAMYHTAKPENRKVVAGLLLSAALTSFLTGITEPVEFSFLFVA
HHCCHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHH
PVLYVIHAFFDGLAFMVAHILHITIGQTFSGGLIDFLLFGVLQGESKTNWMYVPIVGIPW
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHCCCCCCCEEEEEEHHHHH
FFLYYFTFRYLINRFGWLTPGRENVTLVESGQPQSERAAAVIAGLGGKENLEEVDCCATR
HHHHHHHHHHHHHHHCCCCCCCCCEEEEECCCCCHHHHHHHEECCCCCCCHHHHHHHHHH
LRVTVKESSKVDEAALKVTGARGVIIRGNGVQVIYGPHVTIIKNEVEEILS
HEEEECCCCCHHHHHHEEECCCEEEEECCCEEEEECCEEEEEHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 1508157; 9384377; 2497294; 2120236; 1911744; 1906345; 9593197 [H]