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The map label for this gene is yhjH

Identifier: 218697234

GI number: 218697234

Start: 4043581

End: 4044348

Strand: Reverse

Name: yhjH

Synonym: EC55989_3971

Alternate gene names: 218697234

Gene position: 4044348-4043581 (Counterclockwise)

Preceding gene: 218697237

Following gene: 218697233

Centisome position: 78.46

GC content: 53.12

Gene sequence:

>768_bases
ATGATAAGGCAGGTTATCCAGCGAATAAGCAACCCTGAAGCAAGCATCGAGAGCTTGCAGGAACGGCGTTTTTGGTTGCA
GTGTGAGCGTGCTTACACCTGGCAGCCGATCTATCAAACATGCGGGCGGTTAATGGCCGTGGAGCTATTAACGGTGGTCA
CGCATCCCTTGAACCCTTCGCAACGCCTGCCGCCGGATCGCTATTTTACTGAAATCACCGTCAGCCATCGGATGGAGGTT
GTGAAAGAGCAGATTGATTTGTTGGCGCAAAAAGCCGACTTCTTTATAGAGCACGGCCTGCTGGCATCGGTCAATATTGA
TGGCCCTACGCTCATCGCCCTGCGTCAGCAACCAAAAATCCTGCGCCAGATTGAGCGTCTTCCCTGGCTGCGTTTCGAAC
TGGTGGAACACATCCGCCTGCCGAAAGATTCAACCTTTGCCTCGATGTGTGAATTTGGCCCGCTGTGGCTGGATGATTTT
GGCACCGGGATGGCAAATTTCTCTGCGCTAAGTGAAGTGCGTTATGACTACATCAAAATCGCGCGAGAGCTGTTCGTGAT
GCTGCGTCAGTCGCCGGAAGGCCGCACACTCTTTTCTCAGCTTTTACATCTAATGAATCGCTATTGTCGCGGGGTGATTG
TCGAGGGCGTAGAAACACCGGAAGAGTGGCGTGATGTTCAGAACTCGCCCGCATTCGCCGCACAAGGCTGGTTTCTTTCA
CGCCCGGCACCGATAGAAACGCTGAATACGGCGGTTCTGGCGCTATAA

Upstream 100 bases:

>100_bases
GAGGAAATTTACCCCGGCCAGGCGGTAAAGTTCTGCCCTTACGCGCCGATAATCTTTGTCGAGTCCGGGCAGCATCACTT
TTAAACACAGGACATCTTTG

Downstream 100 bases:

>100_bases
GCTGCCTCATTTTCCGCCTGGCTGGACTATCTTTAGGACTGGCACAGGAAGAATATGAGGAAGCGAACGATGAGCAAGGC
AGGCAAAATAACCGCTGCGA

Product: EAL domain-containing protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 255; Mature: 255

Protein sequence:

>255_residues
MIRQVIQRISNPEASIESLQERRFWLQCERAYTWQPIYQTCGRLMAVELLTVVTHPLNPSQRLPPDRYFTEITVSHRMEV
VKEQIDLLAQKADFFIEHGLLASVNIDGPTLIALRQQPKILRQIERLPWLRFELVEHIRLPKDSTFASMCEFGPLWLDDF
GTGMANFSALSEVRYDYIKIARELFVMLRQSPEGRTLFSQLLHLMNRYCRGVIVEGVETPEEWRDVQNSPAFAAQGWFLS
RPAPIETLNTAVLAL

Sequences:

>Translated_255_residues
MIRQVIQRISNPEASIESLQERRFWLQCERAYTWQPIYQTCGRLMAVELLTVVTHPLNPSQRLPPDRYFTEITVSHRMEV
VKEQIDLLAQKADFFIEHGLLASVNIDGPTLIALRQQPKILRQIERLPWLRFELVEHIRLPKDSTFASMCEFGPLWLDDF
GTGMANFSALSEVRYDYIKIARELFVMLRQSPEGRTLFSQLLHLMNRYCRGVIVEGVETPEEWRDVQNSPAFAAQGWFLS
RPAPIETLNTAVLAL
>Mature_255_residues
MIRQVIQRISNPEASIESLQERRFWLQCERAYTWQPIYQTCGRLMAVELLTVVTHPLNPSQRLPPDRYFTEITVSHRMEV
VKEQIDLLAQKADFFIEHGLLASVNIDGPTLIALRQQPKILRQIERLPWLRFELVEHIRLPKDSTFASMCEFGPLWLDDF
GTGMANFSALSEVRYDYIKIARELFVMLRQSPEGRTLFSQLLHLMNRYCRGVIVEGVETPEEWRDVQNSPAFAAQGWFLS
RPAPIETLNTAVLAL

Specific function: A bis-(3'-5') cyclic diguanylic acid (c-di-GMP) phosphodiesterase involved in regulating the levels of c-di-GMP that control cell motility (the flagella) and adhesion (adhesive curli fimbriae). The YhjH effect on flagella is controlled via the c-di-GMP-bi

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 EAL domain

Homologues:

Organism=Escherichia coli, GI87082280, Length=255, Percent_Identity=100, Blast_Score=525, Evalue=1e-150,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): YHJH_ECOLI (P37646)

Other databases:

- EMBL:   U00039
- EMBL:   U00096
- EMBL:   AP009048
- PIR:   H65150
- RefSeq:   AP_004268.1
- RefSeq:   NP_417982.2
- ProteinModelPortal:   P37646
- IntAct:   P37646
- STRING:   P37646
- EnsemblBacteria:   EBESCT00000004859
- EnsemblBacteria:   EBESCT00000015632
- GeneID:   948042
- GenomeReviews:   AP009048_GR
- GenomeReviews:   U00096_GR
- KEGG:   ecj:JW3493
- KEGG:   eco:b3525
- EchoBASE:   EB2162
- EcoGene:   EG12252
- eggNOG:   COG2200
- GeneTree:   EBGT00050000008783
- HOGENOM:   HBG417163
- OMA:   MMIRQVI
- ProtClustDB:   PRK11596
- BioCyc:   EcoCyc:EG12252-MONOMER
- BioCyc:   MetaCyc:EG12252-MONOMER
- Genevestigator:   P37646
- InterPro:   IPR001633
- SMART:   SM00052

Pfam domain/function: PF00563 EAL

EC number: =3.1.4.52

Molecular weight: Translated: 29602; Mature: 29602

Theoretical pI: Translated: 6.36; Mature: 6.36

Prosite motif: PS50883 EAL

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIRQVIQRISNPEASIESLQERRFWLQCERAYTWQPIYQTCGRLMAVELLTVVTHPLNPS
CHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCC
QRLPPDRYFTEITVSHRMEVVKEQIDLLAQKADFFIEHGLLASVNIDGPTLIALRQQPKI
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCEEEEECCCCHH
LRQIERLPWLRFELVEHIRLPKDSTFASMCEFGPLWLDDFGTGMANFSALSEVRYDYIKI
HHHHHHCCCHHHHHHHHHCCCCCCHHHHHHHCCCCCHHHHCCCHHHHHHHHHHHHHHHHH
ARELFVMLRQSPEGRTLFSQLLHLMNRYCRGVIVEGVETPEEWRDVQNSPAFAAQGWFLS
HHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHEEECCCCCCHHHHHCCCCCCCEECCCCCC
RPAPIETLNTAVLAL
CCCCHHHHHHHHHCC
>Mature Secondary Structure
MIRQVIQRISNPEASIESLQERRFWLQCERAYTWQPIYQTCGRLMAVELLTVVTHPLNPS
CHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCC
QRLPPDRYFTEITVSHRMEVVKEQIDLLAQKADFFIEHGLLASVNIDGPTLIALRQQPKI
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCEEEEECCCCHH
LRQIERLPWLRFELVEHIRLPKDSTFASMCEFGPLWLDDFGTGMANFSALSEVRYDYIKI
HHHHHHCCCHHHHHHHHHCCCCCCHHHHHHHCCCCCHHHHCCCHHHHHHHHHHHHHHHHH
ARELFVMLRQSPEGRTLFSQLLHLMNRYCRGVIVEGVETPEEWRDVQNSPAFAAQGWFLS
HHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHEEECCCCCCHHHHHCCCCCCCEECCCCCC
RPAPIETLNTAVLAL
CCCCHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8041620; 9278503