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The map label for this gene is yhaO

Identifier: 218696817

GI number: 218696817

Start: 3610255

End: 3611523

Strand: Reverse

Name: yhaO

Synonym: EC55989_3528

Alternate gene names: 218696817

Gene position: 3611523-3610255 (Counterclockwise)

Preceding gene: 218696818

Following gene: 218696816

Centisome position: 70.06

GC content: 50.28

Gene sequence:

>1269_bases
ATGAGTGAGAGCGAGTGGCGAGAAGCGATCAAATTCGACAGTACTGACACCGGCTGGGTGATTATGAGTATCGGGATGGC
GATTGGCGCGGGGATTGTTTTTCTCCCGGTGCAGGTCGGTTTGATGGGATTGTGGGTATTTTTGCTCTCATCGGTGATTG
GTTACCCGGCAATGTATCTGTTTCAGCGGTTGTTTATTAATACGCTGGCAGAATCACCAGAATGTAAAGATTACCCGAGT
GTCATTAGCGGTTATTTAGGTAAAAACTGGGGCATCCTGTTAGGTGCGCTCTATTTCGTAATGCTGGTGATTTGGATGTT
CGTCTATTCCACCGCCATCACCAACGATAGTGCTTCCTATCTGCATACCTTCGGCGTGACGGAAGGGTTGCTGTCAGACA
GTCCCTTTTATGGTCTGGTACTGATTTGCATTCTGGTGGCGATCTCTTCACGCGGCGAGAAATTGTTATTCAAAATTTCG
ACCGGCATGGTGCTGACCAAGCTGCTGGTGGTCGCGGCGCTGGGCGTGTCGATGGTGGGAATGTGGCATCTGTATAACGT
CGGTTCGCTACCGCCGCTGGGGCTGCTGGTGAAAAACGCCATTATTACGCTGCCGTTTACCCTGACGTCGATTCTGTTTA
TCCAGACGTTAAGCCCGATGGTGATCTCTTATCGCTCGCGGGAAAAATCAATTGAAGTGGCGCGGCATAAAGCATTGCGG
GCAATGAATATCGCGTTTGGCATTTTGTTTGTCACCGTCTTTTTCTACGCCGTGTCGTTCACGCTGGCGATGGGACATGA
CGAAGCGGTAAAAGCCTATGAGCAGAATATTTCCGCGCTGGCGATTGCCGCACAGTTTATTAGCGGTGACGGCGCAGCGT
GGGTGAAAGTGGTCAGCGTCATTCTCAATATCTTTGCTGTCATGACTGCATTCTTTGGCGTCTATTTAGGCTTTCGCGAA
GCAACGCAAGGGATCGTAATGAACATCCTGCGTCGCAAGATGCCTGCCGAGAAGATTAACGAAAATCTCGTTCAGCGCGG
CATCATGATTTTCGCCATTTTGCTGGCCTGGAGCGCCATCGTACTGAACGCACCGGTGTTGAGCTTCACCTCTATCTGTA
GCCCGATTTTCGGCATGGTAGGGTGCCTGATCCCGGCGTGGCTGGTTTACAAAGTACCGGCATTGCACAAATACAAAGGG
ATGTCTCTGTACCTGATTATCGTCACTGGTTTGTTGCTTTGTGTTTCTCCGTTCCTGGCATTTTCTTGA

Upstream 100 bases:

>100_bases
AAAATAATAAGCCCTACAAAATATTGAGCGAGAAATTATGGAAATTGCATCGAATAAAGGCGTCATTGCAGACGCTTCGA
CCCCGGCGGGTCGTGCTGGA

Downstream 100 bases:

>100_bases
TTAACCTGAAATTTTAAGGTTTTTAATATGTTTGATTCGACTTTAAATCCGTTATGGCAGCGTTACATCCTTGCAGTTCA
GGAGGAAGTAAAACCGGCGC

Product: putative transporter

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 422; Mature: 421

Protein sequence:

>422_residues
MSESEWREAIKFDSTDTGWVIMSIGMAIGAGIVFLPVQVGLMGLWVFLLSSVIGYPAMYLFQRLFINTLAESPECKDYPS
VISGYLGKNWGILLGALYFVMLVIWMFVYSTAITNDSASYLHTFGVTEGLLSDSPFYGLVLICILVAISSRGEKLLFKIS
TGMVLTKLLVVAALGVSMVGMWHLYNVGSLPPLGLLVKNAIITLPFTLTSILFIQTLSPMVISYRSREKSIEVARHKALR
AMNIAFGILFVTVFFYAVSFTLAMGHDEAVKAYEQNISALAIAAQFISGDGAAWVKVVSVILNIFAVMTAFFGVYLGFRE
ATQGIVMNILRRKMPAEKINENLVQRGIMIFAILLAWSAIVLNAPVLSFTSICSPIFGMVGCLIPAWLVYKVPALHKYKG
MSLYLIIVTGLLLCVSPFLAFS

Sequences:

>Translated_422_residues
MSESEWREAIKFDSTDTGWVIMSIGMAIGAGIVFLPVQVGLMGLWVFLLSSVIGYPAMYLFQRLFINTLAESPECKDYPS
VISGYLGKNWGILLGALYFVMLVIWMFVYSTAITNDSASYLHTFGVTEGLLSDSPFYGLVLICILVAISSRGEKLLFKIS
TGMVLTKLLVVAALGVSMVGMWHLYNVGSLPPLGLLVKNAIITLPFTLTSILFIQTLSPMVISYRSREKSIEVARHKALR
AMNIAFGILFVTVFFYAVSFTLAMGHDEAVKAYEQNISALAIAAQFISGDGAAWVKVVSVILNIFAVMTAFFGVYLGFRE
ATQGIVMNILRRKMPAEKINENLVQRGIMIFAILLAWSAIVLNAPVLSFTSICSPIFGMVGCLIPAWLVYKVPALHKYKG
MSLYLIIVTGLLLCVSPFLAFS
>Mature_421_residues
SESEWREAIKFDSTDTGWVIMSIGMAIGAGIVFLPVQVGLMGLWVFLLSSVIGYPAMYLFQRLFINTLAESPECKDYPSV
ISGYLGKNWGILLGALYFVMLVIWMFVYSTAITNDSASYLHTFGVTEGLLSDSPFYGLVLICILVAISSRGEKLLFKIST
GMVLTKLLVVAALGVSMVGMWHLYNVGSLPPLGLLVKNAIITLPFTLTSILFIQTLSPMVISYRSREKSIEVARHKALRA
MNIAFGILFVTVFFYAVSFTLAMGHDEAVKAYEQNISALAIAAQFISGDGAAWVKVVSVILNIFAVMTAFFGVYLGFREA
TQGIVMNILRRKMPAEKINENLVQRGIMIFAILLAWSAIVLNAPVLSFTSICSPIFGMVGCLIPAWLVYKVPALHKYKGM
SLYLIIVTGLLLCVSPFLAFS

Specific function: Unknown

COG id: COG0814

COG function: function code E; Amino acid permeases

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the amino acid/polyamine transporter 2 family. SdaC/TdcC subfamily

Homologues:

Organism=Escherichia coli, GI145693183, Length=422, Percent_Identity=100, Blast_Score=846, Evalue=0.0,
Organism=Escherichia coli, GI1789961, Length=408, Percent_Identity=44.6078431372549, Blast_Score=364, Evalue=1e-102,
Organism=Escherichia coli, GI1789160, Length=422, Percent_Identity=28.6729857819905, Blast_Score=134, Evalue=1e-32,
Organism=Escherichia coli, GI1789504, Length=436, Percent_Identity=25.6880733944954, Blast_Score=100, Evalue=1e-22,
Organism=Escherichia coli, GI1789211, Length=411, Percent_Identity=22.6277372262774, Blast_Score=94, Evalue=1e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): YHAO_ECOLI (P42628)

Other databases:

- EMBL:   U18997
- EMBL:   U00096
- EMBL:   AP009048
- RefSeq:   AP_003658.1
- RefSeq:   YP_026203.3
- ProteinModelPortal:   P42628
- STRING:   P42628
- EnsemblBacteria:   EBESCT00000003100
- EnsemblBacteria:   EBESCT00000016515
- GeneID:   947628
- GenomeReviews:   AP009048_GR
- GenomeReviews:   U00096_GR
- KEGG:   ecj:JW5519
- KEGG:   eco:b3110
- EchoBASE:   EB2609
- EcoGene:   EG12754
- eggNOG:   COG0814
- GeneTree:   EBGT00050000008986
- HOGENOM:   HBG297876
- OMA:   AMYLFQK
- ProtClustDB:   CLSK880592
- BioCyc:   EcoCyc:YHAO-MONOMER
- Genevestigator:   P42628
- InterPro:   IPR004694
- TIGRFAMs:   TIGR00814

Pfam domain/function: NA

EC number: NA

Molecular weight: Translated: 46317; Mature: 46186

Theoretical pI: Translated: 9.01; Mature: 9.01

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0x1cafd5b8)-; HASH(0x1c7f0460)-; HASH(0x1cbdb744)-; HASH(0x95e1f88)-; HASH(0x1c27d5d8)-; HASH(0x1cbca76c)-; HASH(0x1c8b5a30)-; HASH(0x1be69084)-; HASH(0x1c3e9a9c)-; HASH(0x16ed3204)-; HASH(0x1c61ef14)-;

Cys/Met content:

1.2 %Cys     (Translated Protein)
4.5 %Met     (Translated Protein)
5.7 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
4.3 %Met     (Mature Protein)
5.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSESEWREAIKFDSTDTGWVIMSIGMAIGAGIVFLPVQVGLMGLWVFLLSSVIGYPAMYL
CCHHHHHHHHHCCCCCCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHCCHHHHH
FQRLFINTLAESPECKDYPSVISGYLGKNWGILLGALYFVMLVIWMFVYSTAITNDSASY
HHHHHHHHHHCCCCCCCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHH
LHTFGVTEGLLSDSPFYGLVLICILVAISSRGEKLLFKISTGMVLTKLLVVAALGVSMVG
HHHHCCHHHHCCCCCHHHHHHHHHHHHHHCCCCEEEEEEHHHHHHHHHHHHHHHHHHHHH
MWHLYNVGSLPPLGLLVKNAIITLPFTLTSILFIQTLSPMVISYRSREKSIEVARHKALR
HHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AMNIAFGILFVTVFFYAVSFTLAMGHDEAVKAYEQNISALAIAAQFISGDGAAWVKVVSV
HHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHH
ILNIFAVMTAFFGVYLGFREATQGIVMNILRRKMPAEKINENLVQRGIMIFAILLAWSAI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHH
VLNAPVLSFTSICSPIFGMVGCLIPAWLVYKVPALHKYKGMSLYLIIVTGLLLCVSPFLA
HHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHCCCHHHHHHHHHHHHHHHHHHH
FS
CH
>Mature Secondary Structure 
SESEWREAIKFDSTDTGWVIMSIGMAIGAGIVFLPVQVGLMGLWVFLLSSVIGYPAMYL
CHHHHHHHHHCCCCCCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHCCHHHHH
FQRLFINTLAESPECKDYPSVISGYLGKNWGILLGALYFVMLVIWMFVYSTAITNDSASY
HHHHHHHHHHCCCCCCCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHH
LHTFGVTEGLLSDSPFYGLVLICILVAISSRGEKLLFKISTGMVLTKLLVVAALGVSMVG
HHHHCCHHHHCCCCCHHHHHHHHHHHHHHCCCCEEEEEEHHHHHHHHHHHHHHHHHHHHH
MWHLYNVGSLPPLGLLVKNAIITLPFTLTSILFIQTLSPMVISYRSREKSIEVARHKALR
HHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AMNIAFGILFVTVFFYAVSFTLAMGHDEAVKAYEQNISALAIAAQFISGDGAAWVKVVSV
HHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHH
ILNIFAVMTAFFGVYLGFREATQGIVMNILRRKMPAEKINENLVQRGIMIFAILLAWSAI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHH
VLNAPVLSFTSICSPIFGMVGCLIPAWLVYKVPALHKYKGMSLYLIIVTGLLLCVSPFLA
HHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHCCCHHHHHHHHHHHHHHHHHHH
FS
CH

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9278503