Click here to switch to the map view.

The map label for this gene is yphH

Identifier: 218696177

GI number: 218696177

Start: 2906216

End: 2907409

Strand: Direct

Name: yphH

Synonym: EC55989_2836

Alternate gene names: 218696177

Gene position: 2906216-2907409 (Clockwise)

Preceding gene: 218696170

Following gene: 218696179

Centisome position: 56.38

GC content: 51.17

Gene sequence:

>1194_bases
ATGAGAGCCTGCATTAACAATCAACAGATTCGCCACCATAACAAATGCGTGATTCTGGAACTGCTGTACCGGCAAAAGCG
CGCCAATAAATCAACGCTGGCCCGGCTGGCGCAAATTTCGATTCCGGCAGTCAGTAATATTTTGCAGGAACTGGAAAGCG
AAAAACGGGTGGTGAATATCGACGATGAAAGCCAGACGCGCGGGCATAGTAGCGGTACATGGCTGATTGCGCCGGAAGGT
GACTGGACGCTGTGCCTGAACGTGACGCCCACCAGTATTGAGTGTCAGGTTGCTAATGCTTGTTTAAGTCCGAAAGGCGA
ATTTGAGTATTTACAGATTGATGTACCGACGCCGCAGGCGCTGCTGTCCGAAATCGAAAAATGCTGGCATCGCCACCGTA
AATTGTGGCCGGACCGCACCATCAATCTGGCGCTGGCAATCCACGGTCAGGTTGATCCAGTGACAGGAGTGTCGCAAACC
ATGCCGCAAGCGCCGTGGACAACGCCGGTTGAGGTGAAGTATCTGCTGGAAGAGAAGCTGGGCATTCGGGTGATGGTCGA
TAATGACTGCGTGATGCTGGCGCTGGCGGAAAAATGGCAAAATAATACGCAGGAACGGGATTTCTGCGTGATCAACGTTG
ATTACGGCATTGGCTCGTCGTTCGTGATTAACGAGCAAATTTATCGCGGCAGTTTGTATGGTAGCGGACAGATTGGTCAC
ACCATCGTTAATCCGGATGGCGTCGTCTGCGACTGTGGACGTTACGGCTGCCTGGAAACCGTCGCCTCGTTAAGCGCATT
AAAAAAACAGGCGCGGGTATGGCTAAAATCACAACCGGTTAATACTCAGCTTGATCCTGAAAAATTGACTACCGCGCAGT
TAATCGCTGCCTGGCAGAGTGGAGAACCGTGGATCACCAGCTGGGTTGACCGCAGTGCCAATGCCATTGGTTTGAGTCTG
TATAACTTCCTCAACATCCTCAATATTAATCAGATTTGGTTGTACGGTCGCAGTTGTGCCTTTGGTGAGAACTGGCTTAA
TACTATTATTCGCCAGACGGGATTTAACCCGTTCGACCGCGACGAAGGACCGAGCGTGAAAGCGACGCAAATTGGCTTCG
GGCAATTAAGCCGCGCACAACAGGTGCTGGGAATTGGCTATTTGTATGTTGAGGCGCAGTTACGACAGATTTGA

Upstream 100 bases:

>100_bases
CAAGACATACTGAATTAAAAGATTTGTGGCAGTGTATTGAACAATCTGGCAATGTTTTCGCGGAATAATCACGCAATTAA
CTAAACAAGGTTTAGTGAAG

Downstream 100 bases:

>100_bases
TGGCGCGATAACGTAGAAAGGCTTCCCGAAGGAAGCCTTTTTTCAACAGATTAACCGTTTCGCTTATGCGTAAACCGGGT
AACGTGCGCAGATGTCGAGA

Product: putative DNA-binding transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 397; Mature: 397

Protein sequence:

>397_residues
MRACINNQQIRHHNKCVILELLYRQKRANKSTLARLAQISIPAVSNILQELESEKRVVNIDDESQTRGHSSGTWLIAPEG
DWTLCLNVTPTSIECQVANACLSPKGEFEYLQIDVPTPQALLSEIEKCWHRHRKLWPDRTINLALAIHGQVDPVTGVSQT
MPQAPWTTPVEVKYLLEEKLGIRVMVDNDCVMLALAEKWQNNTQERDFCVINVDYGIGSSFVINEQIYRGSLYGSGQIGH
TIVNPDGVVCDCGRYGCLETVASLSALKKQARVWLKSQPVNTQLDPEKLTTAQLIAAWQSGEPWITSWVDRSANAIGLSL
YNFLNILNINQIWLYGRSCAFGENWLNTIIRQTGFNPFDRDEGPSVKATQIGFGQLSRAQQVLGIGYLYVEAQLRQI

Sequences:

>Translated_397_residues
MRACINNQQIRHHNKCVILELLYRQKRANKSTLARLAQISIPAVSNILQELESEKRVVNIDDESQTRGHSSGTWLIAPEG
DWTLCLNVTPTSIECQVANACLSPKGEFEYLQIDVPTPQALLSEIEKCWHRHRKLWPDRTINLALAIHGQVDPVTGVSQT
MPQAPWTTPVEVKYLLEEKLGIRVMVDNDCVMLALAEKWQNNTQERDFCVINVDYGIGSSFVINEQIYRGSLYGSGQIGH
TIVNPDGVVCDCGRYGCLETVASLSALKKQARVWLKSQPVNTQLDPEKLTTAQLIAAWQSGEPWITSWVDRSANAIGLSL
YNFLNILNINQIWLYGRSCAFGENWLNTIIRQTGFNPFDRDEGPSVKATQIGFGQLSRAQQVLGIGYLYVEAQLRQI
>Mature_397_residues
MRACINNQQIRHHNKCVILELLYRQKRANKSTLARLAQISIPAVSNILQELESEKRVVNIDDESQTRGHSSGTWLIAPEG
DWTLCLNVTPTSIECQVANACLSPKGEFEYLQIDVPTPQALLSEIEKCWHRHRKLWPDRTINLALAIHGQVDPVTGVSQT
MPQAPWTTPVEVKYLLEEKLGIRVMVDNDCVMLALAEKWQNNTQERDFCVINVDYGIGSSFVINEQIYRGSLYGSGQIGH
TIVNPDGVVCDCGRYGCLETVASLSALKKQARVWLKSQPVNTQLDPEKLTTAQLIAAWQSGEPWITSWVDRSANAIGLSL
YNFLNILNINQIWLYGRSCAFGENWLNTIIRQTGFNPFDRDEGPSVKATQIGFGQLSRAQQVLGIGYLYVEAQLRQI

Specific function: Unknown

COG id: COG1940

COG function: function code KG; Transcriptional regulator/sugar kinase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ROK (nagC/xylR) family [H]

Homologues:

Organism=Homo sapiens, GI298566315, Length=222, Percent_Identity=27.4774774774775, Blast_Score=73, Evalue=4e-13,
Organism=Homo sapiens, GI298566325, Length=222, Percent_Identity=27.4774774774775, Blast_Score=73, Evalue=4e-13,
Organism=Homo sapiens, GI190014632, Length=222, Percent_Identity=27.4774774774775, Blast_Score=73, Evalue=5e-13,
Organism=Homo sapiens, GI4885285, Length=222, Percent_Identity=27.4774774774775, Blast_Score=73, Evalue=5e-13,
Organism=Escherichia coli, GI87082127, Length=397, Percent_Identity=98.992443324937, Blast_Score=814, Evalue=0.0,
Organism=Escherichia coli, GI1787878, Length=333, Percent_Identity=24.024024024024, Blast_Score=99, Evalue=6e-22,
Organism=Escherichia coli, GI1786891, Length=345, Percent_Identity=24.3478260869565, Blast_Score=82, Evalue=6e-17,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000600
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00480 ROK [H]

EC number: NA

Molecular weight: Translated: 44609; Mature: 44609

Theoretical pI: Translated: 6.61; Mature: 6.61

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.0 %Cys     (Translated Protein)
1.0 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
3.0 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRACINNQQIRHHNKCVILELLYRQKRANKSTLARLAQISIPAVSNILQELESEKRVVNI
CCCCCCCCHHHHCCCEEEHHHHHHHHCCCHHHHHHHHHHCHHHHHHHHHHHHCCCCEEEC
DDESQTRGHSSGTWLIAPEGDWTLCLNVTPTSIECQVANACLSPKGEFEYLQIDVPTPQA
CCCHHCCCCCCCEEEEEECCCEEEEEEECCCCEEEEEEHHHCCCCCCEEEEEEECCCHHH
LLSEIEKCWHRHRKLWPDRTINLALAIHGQVDPVTGVSQTMPQAPWTTPVEVKYLLEEKL
HHHHHHHHHHHHHHCCCCCEEEEEEEEECCCCCCCCHHHHCCCCCCCCCHHHHHEEHHCC
GIRVMVDNDCVMLALAEKWQNNTQERDFCVINVDYGIGSSFVINEQIYRGSLYGSGQIGH
CEEEEECCCEEEEEEHHHHCCCCCCCCEEEEEECCCCCCEEEEECHHEECCCCCCCCCCC
TIVNPDGVVCDCGRYGCLETVASLSALKKQARVWLKSQPVNTQLDPEKLTTAQLIAAWQS
EEECCCCCEECCCCCHHHHHHHHHHHHHHHHHHEEECCCCCCCCCHHHHHHHHHHHHHCC
GEPWITSWVDRSANAIGLSLYNFLNILNINQIWLYGRSCAFGENWLNTIIRQTGFNPFDR
CCCHHHHHHHCCCCEEHHHHHHHHHHCCCCEEEEEECCCCCCHHHHHHHHHHCCCCCCCC
DEGPSVKATQIGFGQLSRAQQVLGIGYLYVEAQLRQI
CCCCCEEEEEECCHHHHHHHHHHHEEEEEEEEHHHCC
>Mature Secondary Structure
MRACINNQQIRHHNKCVILELLYRQKRANKSTLARLAQISIPAVSNILQELESEKRVVNI
CCCCCCCCHHHHCCCEEEHHHHHHHHCCCHHHHHHHHHHCHHHHHHHHHHHHCCCCEEEC
DDESQTRGHSSGTWLIAPEGDWTLCLNVTPTSIECQVANACLSPKGEFEYLQIDVPTPQA
CCCHHCCCCCCCEEEEEECCCEEEEEEECCCCEEEEEEHHHCCCCCCEEEEEEECCCHHH
LLSEIEKCWHRHRKLWPDRTINLALAIHGQVDPVTGVSQTMPQAPWTTPVEVKYLLEEKL
HHHHHHHHHHHHHHCCCCCEEEEEEEEECCCCCCCCHHHHCCCCCCCCCHHHHHEEHHCC
GIRVMVDNDCVMLALAEKWQNNTQERDFCVINVDYGIGSSFVINEQIYRGSLYGSGQIGH
CEEEEECCCEEEEEEHHHHCCCCCCCCEEEEEECCCCCCEEEEECHHEECCCCCCCCCCC
TIVNPDGVVCDCGRYGCLETVASLSALKKQARVWLKSQPVNTQLDPEKLTTAQLIAAWQS
EEECCCCCEECCCCCHHHHHHHHHHHHHHHHHHEEECCCCCCCCCHHHHHHHHHHHHHCC
GEPWITSWVDRSANAIGLSLYNFLNILNINQIWLYGRSCAFGENWLNTIIRQTGFNPFDR
CCCHHHHHHHCCCCEEHHHHHHHHHHCCCCEEEEEECCCCCCHHHHHHHHHHCCCCCCCC
DEGPSVKATQIGFGQLSRAQQVLGIGYLYVEAQLRQI
CCCCCEEEEEECCHHHHHHHHHHHEEEEEEEEHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9205837; 9278503 [H]