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The map label for this gene is ypdA

Identifier: 218696023

GI number: 218696023

Start: 2731050

End: 2732747

Strand: Direct

Name: ypdA

Synonym: EC55989_2676

Alternate gene names: 218696023

Gene position: 2731050-2732747 (Clockwise)

Preceding gene: 218696021

Following gene: 218696024

Centisome position: 52.98

GC content: 50.82

Gene sequence:

>1698_bases
GTGCACGAAATATTCAACATGCTGCTGGCGGTCTTCGATCGGGCAGCGTTAATGCTTATCTGCCTGTTCTTTCTCATCCG
TATCCGCCTGTTTCGCGAACTGTTGCACAAGTCGGCGCACTCCCCAAAAGAATTGCTCGCCGTTACCGCCATTTTCTCGC
TGTTCGCCCTGTTCAGCACCTGGTCCGGCGTTCCCGTAGAAGGCTCGCTGGTGAACGTACGTATTATCGCGGTGATGTCC
GGCGGGATTCTGTTTGGCCCGTGGGTAGGCATCATTACCGGCGTGATTGCGGGTATTCACCGGTATTTAATTGATATCGG
CGGCGTGACGGCGATCCCCTGCTTTATCACCAGCATTCTGGCGGGTTGTATATCAGGCTGGATAAACCTGAAAATCCCCA
AAGCACAGCGCTGGCGCGTCGGTATTCTCGGCGGCATGTTGTGTGAGACGTTGACCATGATTCTGGTAATTGTCTGGGCA
CCAACTACCGCGTTGGGGATCGATATCGTCTCTAAAATCGGCATTCCAATGATCCTCGGTAGCGTCTGTATCGGCTTTAT
TGTGCTTCTGGTGCAAAGCGTTGAGGGCGAAAAAGAGGCCAGCGCCGCGCGGCAGGCCAAGCTGGCGCTGGATATCGCCA
ACAAAACGCTACCTCTGTTTCGCCATGTCAATAGCGAGTCATTACGCAAAGTTTGTGAAATTATTCGCGATGACATTCAC
GCCGATGCGGTGGCGATTACCAATACCGATCATGTGCTGGCCTATGTTGGCGTGGGTGAACATAACTATCAGAATGGCGA
TGACTTCATTAGCCCGACTACCCGTCAGGCGATGAATTACGGAAAAATCATCATTAAAAACAATGATGAAGCCCACCGCA
CACCAGAGATTCATTCCATGCTGGTGATCCCATTGTGGGAGAAAGGCGTTGTGACCGGAACGCTGAAAATTTACTACTGC
CACGCGCATCAGATCACCTCGTCATTACAGGAAATGGCGGTCGGTCTGTCGCAAATCATCTCCACCCAACTGGAGGTTTC
ACGCGCCGAGCAGCTACGTGAAATGGCAAATAAGGCAGAGCTTCGCGCCCTGCAAAGCAAAATTAATCCCCATTTCCTGT
TTAACGCTTTGAACGCTATTTCATCATCAATCCGTCTGAATCCGGATACTGCTCGCCAGCTGATCTTTAATCTGTCGCGT
TATCTGCGCTATAACATTGAATTAAAAGACGATGAGCAAATCGATATCAAAAAAGAGCTGTATCAAATTAAAGACTATAT
TGCCATTGAGCAGGCCCGCTTTGGCGACAAGCTGACGGTTATCTATGATATTGATGAAGAGGTGAATTGCTGCATTCCCA
GCCTGCTGATCCAGCCGTTGGTGGAGAATGCCATTGTCCACGGTATTCAGCCTTGCAAAGGTAAAGGCGTTGTCACCATC
AGCGTTGCAGAGTGCGGCAATCGGGTACGCATTGCGGTGCGGGATACCGGGCACGGCATCGATCCAAAGGTGATTGAGCG
GGTCGAAGCGAATGAAATGCCGGGCAATAAAATTGGCCTGCTGAATGTTCATCATCGCGTGAAGTTATTGTATGGCGAGG
GGCTGCATATCCGCCGCCTGGAACCAGGAACGGAAATTGCGTTTTACATTCCTAACCAACGCACCCCAGTCGCCTCACAG
GCTACGTTATTGCTTTGA

Upstream 100 bases:

>100_bases
ATCCCCTTTTAAATTTATGGTTTTTCCTCAAAAACGGCCTGCTGGTCATCAGCCTTCAGGTTACCTATCATAGAGGTTTA
ATCCTTATTCAGAGTCACCC

Downstream 100 bases:

>100_bases
GCCGGAGTGATATTGTGAAAGTCATCATTGTTGAAGACGAATTCCTGGCACAACAGGAACTGAGCTGGCTAATTAAAGAG
CACAGCCAGATGGAGATTGT

Product: putative sensory kinase in two-component system with YpdB

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 565; Mature: 565

Protein sequence:

>565_residues
MHEIFNMLLAVFDRAALMLICLFFLIRIRLFRELLHKSAHSPKELLAVTAIFSLFALFSTWSGVPVEGSLVNVRIIAVMS
GGILFGPWVGIITGVIAGIHRYLIDIGGVTAIPCFITSILAGCISGWINLKIPKAQRWRVGILGGMLCETLTMILVIVWA
PTTALGIDIVSKIGIPMILGSVCIGFIVLLVQSVEGEKEASAARQAKLALDIANKTLPLFRHVNSESLRKVCEIIRDDIH
ADAVAITNTDHVLAYVGVGEHNYQNGDDFISPTTRQAMNYGKIIIKNNDEAHRTPEIHSMLVIPLWEKGVVTGTLKIYYC
HAHQITSSLQEMAVGLSQIISTQLEVSRAEQLREMANKAELRALQSKINPHFLFNALNAISSSIRLNPDTARQLIFNLSR
YLRYNIELKDDEQIDIKKELYQIKDYIAIEQARFGDKLTVIYDIDEEVNCCIPSLLIQPLVENAIVHGIQPCKGKGVVTI
SVAECGNRVRIAVRDTGHGIDPKVIERVEANEMPGNKIGLLNVHHRVKLLYGEGLHIRRLEPGTEIAFYIPNQRTPVASQ
ATLLL

Sequences:

>Translated_565_residues
MHEIFNMLLAVFDRAALMLICLFFLIRIRLFRELLHKSAHSPKELLAVTAIFSLFALFSTWSGVPVEGSLVNVRIIAVMS
GGILFGPWVGIITGVIAGIHRYLIDIGGVTAIPCFITSILAGCISGWINLKIPKAQRWRVGILGGMLCETLTMILVIVWA
PTTALGIDIVSKIGIPMILGSVCIGFIVLLVQSVEGEKEASAARQAKLALDIANKTLPLFRHVNSESLRKVCEIIRDDIH
ADAVAITNTDHVLAYVGVGEHNYQNGDDFISPTTRQAMNYGKIIIKNNDEAHRTPEIHSMLVIPLWEKGVVTGTLKIYYC
HAHQITSSLQEMAVGLSQIISTQLEVSRAEQLREMANKAELRALQSKINPHFLFNALNAISSSIRLNPDTARQLIFNLSR
YLRYNIELKDDEQIDIKKELYQIKDYIAIEQARFGDKLTVIYDIDEEVNCCIPSLLIQPLVENAIVHGIQPCKGKGVVTI
SVAECGNRVRIAVRDTGHGIDPKVIERVEANEMPGNKIGLLNVHHRVKLLYGEGLHIRRLEPGTEIAFYIPNQRTPVASQ
ATLLL
>Mature_565_residues
MHEIFNMLLAVFDRAALMLICLFFLIRIRLFRELLHKSAHSPKELLAVTAIFSLFALFSTWSGVPVEGSLVNVRIIAVMS
GGILFGPWVGIITGVIAGIHRYLIDIGGVTAIPCFITSILAGCISGWINLKIPKAQRWRVGILGGMLCETLTMILVIVWA
PTTALGIDIVSKIGIPMILGSVCIGFIVLLVQSVEGEKEASAARQAKLALDIANKTLPLFRHVNSESLRKVCEIIRDDIH
ADAVAITNTDHVLAYVGVGEHNYQNGDDFISPTTRQAMNYGKIIIKNNDEAHRTPEIHSMLVIPLWEKGVVTGTLKIYYC
HAHQITSSLQEMAVGLSQIISTQLEVSRAEQLREMANKAELRALQSKINPHFLFNALNAISSSIRLNPDTARQLIFNLSR
YLRYNIELKDDEQIDIKKELYQIKDYIAIEQARFGDKLTVIYDIDEEVNCCIPSLLIQPLVENAIVHGIQPCKGKGVVTI
SVAECGNRVRIAVRDTGHGIDPKVIERVEANEMPGNKIGLLNVHHRVKLLYGEGLHIRRLEPGTEIAFYIPNQRTPVASQ
ATLLL

Specific function: Unknown

COG id: COG3275

COG function: function code T; Putative regulator of cell autolysis

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Escherichia coli, GI1788723, Length=565, Percent_Identity=100, Blast_Score=1154, Evalue=0.0,
Organism=Escherichia coli, GI1788446, Length=516, Percent_Identity=29.4573643410853, Blast_Score=202, Evalue=6e-53,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): YPDA_ECO57 (P0AA94)

Other databases:

- EMBL:   AE005174
- EMBL:   BA000007
- PIR:   D91036
- PIR:   F85880
- RefSeq:   NP_288950.1
- RefSeq:   NP_311287.1
- ProteinModelPortal:   P0AA94
- SMR:   P0AA94
- EnsemblBacteria:   EBESCT00000028016
- EnsemblBacteria:   EBESCT00000059631
- GeneID:   915638
- GeneID:   957579
- GenomeReviews:   AE005174_GR
- GenomeReviews:   BA000007_GR
- KEGG:   ece:Z3645
- KEGG:   ecs:ECs3260
- GeneTree:   EBGT00050000008644
- HOGENOM:   HBG724694
- OMA:   VIYDIDD
- ProtClustDB:   CLSK880374
- BioCyc:   ECOL83334:ECS3260-MONOMER
- InterPro:   IPR003594
- InterPro:   IPR003018
- InterPro:   IPR010559
- InterPro:   IPR011620
- Gene3D:   G3DSA:3.30.565.10
- SMART:   SM00065
- SMART:   SM00387

Pfam domain/function: PF07694 5TM-5TMR_LYT; PF02518 HATPase_c; PF06580 His_kinase; SSF55874 ATP_bd_ATPase

EC number: 2.7.3.-

Molecular weight: Translated: 62658; Mature: 62658

Theoretical pI: Translated: 7.77; Mature: 7.77

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0x1a8a3884)-; HASH(0x1b7bf5f4)-; HASH(0x1ae12a64)-; HASH(0x1b746bc8)-; HASH(0x1b3b4f7c)-; HASH(0x1a4f5c18)-;

Cys/Met content:

1.9 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MHEIFNMLLAVFDRAALMLICLFFLIRIRLFRELLHKSAHSPKELLAVTAIFSLFALFST
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHC
WSGVPVEGSLVNVRIIAVMSGGILFGPWVGIITGVIAGIHRYLIDIGGVTAIPCFITSIL
CCCCCCCCCEEEEEEEEEEECCEEEHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHH
AGCISGWINLKIPKAQRWRVGILGGMLCETLTMILVIVWAPTTALGIDIVSKIGIPMILG
HHHHCCCEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCHHHHHH
SVCIGFIVLLVQSVEGEKEASAARQAKLALDIANKTLPLFRHVNSESLRKVCEIIRDDIH
HHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCHHHHHCCCHHHHHHHHHHHHHHHC
ADAVAITNTDHVLAYVGVGEHNYQNGDDFISPTTRQAMNYGKIIIKNNDEAHRTPEIHSM
CCEEEEECCCCEEEEEECCCCCCCCCCCCCCCCHHHHHCCCEEEEECCCCCCCCCCHHCE
LVIPLWEKGVVTGTLKIYYCHAHQITSSLQEMAVGLSQIISTQLEVSRAEQLREMANKAE
EEEEECCCCEEEEEEEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LRALQSKINPHFLFNALNAISSSIRLNPDTARQLIFNLSRYLRYNIELKDDEQIDIKKEL
HHHHHHHCCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHEEEEEECCCCCCHHHHHH
YQIKDYIAIEQARFGDKLTVIYDIDEEVNCCIPSLLIQPLVENAIVHGIQPCKGKGVVTI
HHHHHHHHHHHHCCCCEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEE
SVAECGNRVRIAVRDTGHGIDPKVIERVEANEMPGNKIGLLNVHHRVKLLYGEGLHIRRL
EHHHCCCEEEEEEECCCCCCCHHHHHHHHCCCCCCCEEEEEEECEEEEEEECCCEEEEEE
EPGTEIAFYIPNQRTPVASQATLLL
CCCCEEEEEECCCCCCCCCCCEECH
>Mature Secondary Structure
MHEIFNMLLAVFDRAALMLICLFFLIRIRLFRELLHKSAHSPKELLAVTAIFSLFALFST
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHC
WSGVPVEGSLVNVRIIAVMSGGILFGPWVGIITGVIAGIHRYLIDIGGVTAIPCFITSIL
CCCCCCCCCEEEEEEEEEEECCEEEHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHH
AGCISGWINLKIPKAQRWRVGILGGMLCETLTMILVIVWAPTTALGIDIVSKIGIPMILG
HHHHCCCEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCHHHHHH
SVCIGFIVLLVQSVEGEKEASAARQAKLALDIANKTLPLFRHVNSESLRKVCEIIRDDIH
HHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCHHHHHCCCHHHHHHHHHHHHHHHC
ADAVAITNTDHVLAYVGVGEHNYQNGDDFISPTTRQAMNYGKIIIKNNDEAHRTPEIHSM
CCEEEEECCCCEEEEEECCCCCCCCCCCCCCCCHHHHHCCCEEEEECCCCCCCCCCHHCE
LVIPLWEKGVVTGTLKIYYCHAHQITSSLQEMAVGLSQIISTQLEVSRAEQLREMANKAE
EEEEECCCCEEEEEEEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LRALQSKINPHFLFNALNAISSSIRLNPDTARQLIFNLSRYLRYNIELKDDEQIDIKKEL
HHHHHHHCCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHEEEEEECCCCCCHHHHHH
YQIKDYIAIEQARFGDKLTVIYDIDEEVNCCIPSLLIQPLVENAIVHGIQPCKGKGVVTI
HHHHHHHHHHHHCCCCEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEE
SVAECGNRVRIAVRDTGHGIDPKVIERVEANEMPGNKIGLLNVHHRVKLLYGEGLHIRRL
EHHHCCCEEEEEEECCCCCCCHHHHHHHHCCCCCCCEEEEEEECEEEEEEECCCEEEEEE
EPGTEIAFYIPNQRTPVASQATLLL
CCCCEEEEEECCCCCCCCCCCEECH

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796