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The map label for this gene is elaD

Identifier: 218695872

GI number: 218695872

Start: 2584736

End: 2585956

Strand: Direct

Name: elaD

Synonym: EC55989_2517

Alternate gene names: 218695872

Gene position: 2584736-2585956 (Clockwise)

Preceding gene: 218695871

Following gene: 218695873

Centisome position: 50.14

GC content: 35.79

Gene sequence:

>1221_bases
ATGATGGTTACAGTTGTCAGCAATTATTGTCAATTATCTCAAAAGCAACTCAGTCAGACATTTGCAGAAAAATTTACTGT
GACCGAGGAATTACTGCAGTCTTTAAAAAAAACAGCGTTATCCGGAGATGAAGAAAGCATTGAGTTACTGCATAATATTG
CGTTAGGTTATGATAAATTTGGAAAAGAAGCTGAAGACATTCTTTACCATATTGTTAGAAACCCAACAAATGAGACCCTA
TCGATTATCCGACTTATCAAAAATGCTTGTTTAAAATTATATAATTTGGCACATACCGCAACCAACTTCCCCCTTAAACC
AACTGGTCCGGATAATTCAGATGTTCTCCTGTTCAAAAAGCTATTCTCCCCTTCGAAATTAATGACAATTATCGGTGATG
AAATTCCTCTTATATCTGAAAAACAGTCGCTTTCGAAGGTGCTTTTAAATGATGAGAATAATGAACTGAGTGATGGTACA
AACTTCTGGGATAAAAATCGTCAATTAACCACAGATGAAATAGATTGCTATCTTCAGAAGATCGCCGCTAATGCAAAAAA
TACTGAAGTCAATTATCCTACTGGTCTCTACGTCCCCTACTCCACCAGAACTCACCTGGAAGACGCTCTCAATGAAAATA
TTAAGAGCGATCCATCATGGCCGAAAGCAGTCCAGTTATTCCCCATAAATACTGGCGGACACTGGATATTAGTTTCGCTA
CAGAAAATAGTAAATGAAAAAAATAATACACAACAAATAAAATGCGTCATATTCAACTCATTGCGCGCACTAGGCCATGA
TAAAGAAAATTCACTTAAGCGTGTCATTAATAGTTTTAATTCTGAATTCATGGGAGAAATGTCTAATAATAATATAAAAG
TTCATTTAACTGAACCCGAGATAATATTTTTACATGCCGATCTTCAGCAATATTTAAGCCAAAGTTGCGGTGCATTTGTG
TGCATGGCAGCCCAGGAAGTGATTGAACAAAGGGAAAGCAATTCTGACAGCGCCCCCTATACGTTATTAAAAAACTATGC
TGACAGATTTAAAAAATATTCAGCAGAAGAGCAGTACGAAATTGATTTTCAACATAGACTGGTAAACAGAAATTGTTATT
TAGATAAATATGGCGATGCACGAATCAATGCTTCTTATACACAATTAGAAATAAAACACTCACAACCCAAAAATAGAGCA
TCCGGCAAAAGAGTGAGTTAA

Upstream 100 bases:

>100_bases
ATTTTTGATATTTATTCATCTCCTCACGCACTATATTCAGAGCAATAAGTTGCCTCTATTTATCTTGATTCAGCACAACC
TTTGCAACTAAAAGGAGCCC

Downstream 100 bases:

>100_bases
CATCATTGTTAATTAATTCGACCAGTCAGCAAATATGCTGACTGGTCGAACATAGTTTGCTAAACAGTCATCACTGACTG
ATGTCAGTCACACCATCCGC

Product: deubiquitinase

Products: NA

Alternate protein names: Deubiquitinase; Deubiquitinating enzyme; DUB; Deubiquitinating protease

Number of amino acids: Translated: 406; Mature: 406

Protein sequence:

>406_residues
MMVTVVSNYCQLSQKQLSQTFAEKFTVTEELLQSLKKTALSGDEESIELLHNIALGYDKFGKEAEDILYHIVRNPTNETL
SIIRLIKNACLKLYNLAHTATNFPLKPTGPDNSDVLLFKKLFSPSKLMTIIGDEIPLISEKQSLSKVLLNDENNELSDGT
NFWDKNRQLTTDEIDCYLQKIAANAKNTEVNYPTGLYVPYSTRTHLEDALNENIKSDPSWPKAVQLFPINTGGHWILVSL
QKIVNEKNNTQQIKCVIFNSLRALGHDKENSLKRVINSFNSEFMGEMSNNNIKVHLTEPEIIFLHADLQQYLSQSCGAFV
CMAAQEVIEQRESNSDSAPYTLLKNYADRFKKYSAEEQYEIDFQHRLVNRNCYLDKYGDARINASYTQLEIKHSQPKNRA
SGKRVS

Sequences:

>Translated_406_residues
MMVTVVSNYCQLSQKQLSQTFAEKFTVTEELLQSLKKTALSGDEESIELLHNIALGYDKFGKEAEDILYHIVRNPTNETL
SIIRLIKNACLKLYNLAHTATNFPLKPTGPDNSDVLLFKKLFSPSKLMTIIGDEIPLISEKQSLSKVLLNDENNELSDGT
NFWDKNRQLTTDEIDCYLQKIAANAKNTEVNYPTGLYVPYSTRTHLEDALNENIKSDPSWPKAVQLFPINTGGHWILVSL
QKIVNEKNNTQQIKCVIFNSLRALGHDKENSLKRVINSFNSEFMGEMSNNNIKVHLTEPEIIFLHADLQQYLSQSCGAFV
CMAAQEVIEQRESNSDSAPYTLLKNYADRFKKYSAEEQYEIDFQHRLVNRNCYLDKYGDARINASYTQLEIKHSQPKNRA
SGKRVS
>Mature_406_residues
MMVTVVSNYCQLSQKQLSQTFAEKFTVTEELLQSLKKTALSGDEESIELLHNIALGYDKFGKEAEDILYHIVRNPTNETL
SIIRLIKNACLKLYNLAHTATNFPLKPTGPDNSDVLLFKKLFSPSKLMTIIGDEIPLISEKQSLSKVLLNDENNELSDGT
NFWDKNRQLTTDEIDCYLQKIAANAKNTEVNYPTGLYVPYSTRTHLEDALNENIKSDPSWPKAVQLFPINTGGHWILVSL
QKIVNEKNNTQQIKCVIFNSLRALGHDKENSLKRVINSFNSEFMGEMSNNNIKVHLTEPEIIFLHADLQQYLSQSCGAFV
CMAAQEVIEQRESNSDSAPYTLLKNYADRFKKYSAEEQYEIDFQHRLVNRNCYLDKYGDARINASYTQLEIKHSQPKNRA
SGKRVS

Specific function: Protease that can act as an efficient and specific deubiquitinating enzyme in vitro. Does not possess desumoylating and deneddylating activities. The physiological substrate is unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase C79 family

Homologues:

Organism=Escherichia coli, GI1788604, Length=406, Percent_Identity=93.1034482758621, Blast_Score=770, Evalue=0.0,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): ELAD_ECO24 (A7ZP88)

Other databases:

- EMBL:   CP000800
- RefSeq:   YP_001463617.1
- ProteinModelPortal:   A7ZP88
- STRING:   A7ZP88
- EnsemblBacteria:   EBESCT00000020096
- GeneID:   5588470
- GenomeReviews:   CP000800_GR
- KEGG:   ecw:EcE24377A_2566
- NMPDR:   fig|331111.3.peg.302
- eggNOG:   NOG13740
- GeneTree:   EBGT00050000009525
- HOGENOM:   HBG467152
- ProtClustDB:   PRK11836
- BioCyc:   ECOL331111:ECE24377A_2566-MONOMER
- GO:   GO:0006508
- InterPro:   IPR003653

Pfam domain/function: PF02902 Peptidase_C48

EC number: NA

Molecular weight: Translated: 46291; Mature: 46291

Theoretical pI: Translated: 6.51; Mature: 6.51

Prosite motif: NA

Important sites: ACT_SITE 234-234 ACT_SITE 316-316

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MMVTVVSNYCQLSQKQLSQTFAEKFTVTEELLQSLKKTALSGDEESIELLHNIALGYDKF
CEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCHHHH
GKEAEDILYHIVRNPTNETLSIIRLIKNACLKLYNLAHTATNFPLKPTGPDNSDVLLFKK
CCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCEEEEHH
LFSPSKLMTIIGDEIPLISEKQSLSKVLLNDENNELSDGTNFWDKNRQLTTDEIDCYLQK
HCCCHHHHHHHCCCCCCCCCHHHHHHHHHCCCCCCCCCCCCHHCCCCCCCHHHHHHHHHH
IAANAKNTEVNYPTGLYVPYSTRTHLEDALNENIKSDPSWPKAVQLFPINTGGHWILVSL
HHCCCCCCCCCCCCEEEEECCCHHHHHHHHHCCCCCCCCCCCEEEEEEECCCCCEEEEEH
QKIVNEKNNTQQIKCVIFNSLRALGHDKENSLKRVINSFNSEFMGEMSNNNIKVHLTEPE
HHHHCCCCCCCEEEHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCC
IIFLHADLQQYLSQSCGAFVCMAAQEVIEQRESNSDSAPYTLLKNYADRFKKYSAEEQYE
EEEEECHHHHHHHHCCHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHCCCCCCEE
IDFQHRLVNRNCYLDKYGDARINASYTQLEIKHSQPKNRASGKRVS
CCHHHHHHCCCCEEECCCCCEECCCEEEEEEECCCCCCCCCCCCCC
>Mature Secondary Structure
MMVTVVSNYCQLSQKQLSQTFAEKFTVTEELLQSLKKTALSGDEESIELLHNIALGYDKF
CEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCHHHH
GKEAEDILYHIVRNPTNETLSIIRLIKNACLKLYNLAHTATNFPLKPTGPDNSDVLLFKK
CCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCEEEEHH
LFSPSKLMTIIGDEIPLISEKQSLSKVLLNDENNELSDGTNFWDKNRQLTTDEIDCYLQK
HCCCHHHHHHHCCCCCCCCCHHHHHHHHHCCCCCCCCCCCCHHCCCCCCCHHHHHHHHHH
IAANAKNTEVNYPTGLYVPYSTRTHLEDALNENIKSDPSWPKAVQLFPINTGGHWILVSL
HHCCCCCCCCCCCCEEEEECCCHHHHHHHHHCCCCCCCCCCCEEEEEEECCCCCEEEEEH
QKIVNEKNNTQQIKCVIFNSLRALGHDKENSLKRVINSFNSEFMGEMSNNNIKVHLTEPE
HHHHCCCCCCCEEEHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCC
IIFLHADLQQYLSQSCGAFVCMAAQEVIEQRESNSDSAPYTLLKNYADRFKKYSAEEQYE
EEEEECHHHHHHHHCCHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHCCCCCCEE
IDFQHRLVNRNCYLDKYGDARINASYTQLEIKHSQPKNRASGKRVS
CCHHHHHHCCCCEEECCCCCEECCCEEEEEEECCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA